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Science is the answer

image of HT magazine logo summer 2020 edition
Curiosity driven research done here at CSHL and by scientists around the world is why the scientific community has been able to respond so rapidly to the challenges of the COVID-19 pandemic. In this time of crisis, CSHL reiterates its research focus on molecular biology and genetics in the fields of cancer, neuroscience, genomics & quantitative biology, and plant biology.”

2019 Research highlights

Hundreds of scientists working in Cold Spring Harbor Laboratory’s 50-plus laboratory groups contributed to research that in 2019 was published in the world’s major research journals. Their efforts reflect the full spectrum of this institution’s scientific activity in cancer, neuroscience, genomics & quantitative biology, and plant biology. The following is a sampling of this year’s important findings.

Research area by funding

Practical applications of research

The Laboratory’s 130 years are rich with discoveries in biology and genetics that have had major impacts on society in human health, agricultural production, and the environment. Grounded in basic research, CSHL’s multi-disciplinary approach to cancer, neuroscience, genomics & quantitative biology, and plant biology continues to enhance our understanding of life.

The Office of Technology Transfer actively supports our scientists to partner with companies, investors and others in order to achieve this mission and make a positive impact on society. The Laboratory is engaged in technology transfer as one way of delivering important discoveries to the public.


Understanding fundamental cellular processes that are the basis of life, and how they go wrong in cancer. Improving diagnosis and treatment of all major cancers: brain, breast, colon, leukemia, lung, lymphoma, melanoma, ovarian, pancreatic, and prostate.


Exploring the brain to identify the neural networks involved in sensory processing, cognition, and decision-making. Providing insight into disorders such as Alzheimer’s, autism, schizophrenia, bipolar disorder, and depression.

Genomics & Quantitative Biology

Using cutting-edge technology to read the genome of organisms, tumors, or even single cells. Creating innovative data analysis tools to develop disease diagnostics and therapeutics.

Plant Biology

Investigating the mechanisms of plant development and genetics. Improving crop yields, increasing biodiversity, and developing biofuels.

graphic of a word cloud built around the diseases studied by CSHL researchers