My research team studies the genes that determine when and where, and thus how many, flowers are produced on plants. Flowers form on branches called inflorescences, which originate from stem cells. By studying the genes that control how stem cells become inflorescences, we are able to manipulate flower production to improve crop yields.
Zachary Lippman’s research focuses on the process of flowering and flower production in plants, which are major contributors to reproductive success and crop yield. Specifically, Lippman’s research program integrates development, genetics, genomics, and gene editing to explore the mechanisms that determine how plant stem cells become shoots and flowers. The lab takes advantage of extensive natural and mutant variation in inflorescence production and architecture in tomato and related nightshade species (e.g. potato, pepper, groundcherry) to explore how differences in these processes explain the remarkable diversity in the architectures of flower-bearing shoots (inflorescences) observed in nature and agriculture. Recent discoveries on the genes and networks underlying this diversity have led to broader questions on the significance of genomic structural variation, gene redundancy, and epistasis in development, domestication, and breeding. Based on our fundamental discoveries, Lippman is developing and applying innovative concepts and tools for crop improvement.
A home like no other, Cold Spring Harbor Laboratory
November 7, 2019
Hear why our campus, our community, and our collaborative nature makes us a place that so many scientists call "home."
Zachary Lippman named 2019 MacArthur Fellow
September 25, 2019
Cold Spring Harbor Laboratory Professor and HHMI Investigator Zachary Lippman has been named a 2019 MacArthur Fellow.
The next agricultural revolution is here
September 19, 2019
After reviewing decades of plant research, scientists suggest that with past lessons and modern tools, the next agricultural revolution is at hand.
An essay from the President: Biology for the planet
May 16, 2019
CSHL plant scientists are looking for solutions to the biggest questions in agriculture as environments are reshaped by climate change.
Cryptic mutation is cautionary tale for crop gene editing
May 6, 2019
Unexpected interactions between mutations can be a thorn in the side for plant breeders. Scientists unveil what drove one infamous “cryptic” mutation.
Cold Spring Harbor Laboratory announces exclusive license with plant breeding start-up Inari
April 16, 2019
CSHL announced a licensing agreement with partner Inari, a company that is advancing plant breeding by tapping nature’s genetic diversity.
To protect stem cells, plants have diverse genetic backup plans
April 15, 2019
Experts discover how an essential genetic circuit found in all flowering plants, regardless of species, is protected in startlingly different ways.
The year of CRISPR
December 26, 2018
A look at the various labs across CSHL that utilize CRISPR in their research, and the groundbreaking discoveries they help uncover.
CRISPR could bring groundcherries to market
October 1, 2018
CSHL Professor Zachary Lippman uses CRISPR to make the groundcherry more suitable for large-scale farming
A science writer’s quest to understand heredity
May 30, 2018
LabDish spoke with science writer Carl Zimmer about what he learned about heredity as he zig-zagged through CSHL while writing his new book.