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Partha Mitra

Partha P. Mitra

Professor

Ph.D., Harvard University, 1993

mitra@cshl.edu | 516-367-6942

Mitra Lab Website   Faculty Profile

A theoretical physicist by training, my research is centered around intelligent machines. I do both theoretical and experimental work. The theoretical work is focussed on analyzing distributed/networked algorithms in the context of control theory and machine learning, using tools from statistical physics. My lab is involved in brain-wide mesoscale circuit mapping in the Mouse as well as in the Marmoset. An organizing idea behind my research is that there may be common underlying mathematical principles that constrain evolved biological systems and human-engineered systems.

Partha Mitra is interested in understanding intelligent machines that are products of biological evolution (particularly animal brains), with the basic hypothesis that common underlying principles may govern these “wet” intelligent machines and the “dry” intelligent machines that are transforming the present economy. Dr Mitra initiated the idea of brain-wide mesoscale circuit mapping, and his laboratory is involved in carrying out such mapping in the Mouse (http://mouse.brainarchitecture.org) and the Marmoset (in collaboration with Japanese and Australian scientists at the RIKEN Brain Science Institute and Monash University).

Dr Mitra spent ten years as a member of the theory department at Bell Laboratories and holds a visiting professorship at IIT Madras where he is helping establish the Center for Computational Brain Research. He has an active theoretical research program in machine learning and control theory, wheren he is using tools from statistical physics to analyze the performance of distributed/networked algorithms in the “thermodynamic” limit of many variables.

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Selected Publications

Fitting elephants in modern machine learning by statistically consistent interpolation

1 May 2021 | Nature Machine Intelligence | 3(5):378-386
Mitra, P

A multimodal cell census and atlas of the mammalian primary motor cortex

21 Oct 2020 | bioRxiv
BRAIN Initiative Cell Census Network (BICCN), Adkins, Ricky, Aldridge, Andrew, Allen, Shona, Ament, Seth, An, Xu, Armand, Ethan, Ascoli, Giorgio, Bakken, Trygve, Bandrowski, Anita, Banerjee, Samik, Barkas, Nikolaos, Bartlett, Anna, Bateup, Helen, Behrens, Margarita, Berens, Philipp, Berg, Jim, Bernabucci, Matteo, Bernaerts, Yves, Bertagnolli, Darren, Biancalani, Tommaso, Boggeman, Lara, Booeshaghi, Sina, Bowman, Ian, Bravo, Héctor, Cadwell, Cathryn, Callaway, Edward, Carlin, Benjamin, O'Connor, Carolyn, Carter, Robert, Casper, Tamara, Castanon, Rosa, Castro, Jesus, Chance, Rebecca, Chatterjee, Apaala, Chen, Huaming, Chun, Jerold, Colantuoni, Carlo, Crabtree, Jonathan, Creasy, Heather, Crichton, Kirsten, Crow, Megan, D'Orazi, Florence, Daigle, Tanya, Dalley, Rachel, Dee, Nick, Degatano, Kylee, Dichter, Benjamin, Diep, Dinh, Ding, Liya, Ding, Song-Lin, Dominguez, Bertha, Dong, Hong-Wei, Dong, Weixiu, Dougherty, Elizabeth, Dudoit, Sandrine, Ecker, Joseph, Eichhorn, Stephen, Fang, Rongxin, Felix, Victor, Feng, Guoping, Feng, Zhao, Fischer, Stephan, Fitzpatrick, Conor, Fong, Olivia, Foster, Nicholas, Galbavy, William, Gee, James, Ghosh, Satrajit, Giglio, Michelle, Gillespie, Thomas, Gillis, Jesse, Goldman, Melissa, Goldy, Jeff, Gong, Hui, Gou, Lin, Grauer, Michael, Halchenko, Yaroslav, Harris, Julie, Hartmanis, Leonard, Hatfield, Joshua, Hawrylycz, Mike, Helba, Brian, Herb, Brian, Hertzano, Ronna, Hintiryan, Houri, Hirokawa, Karla, Hockemeyer, Dirk, Hodge, Rebecca, Hood, Greg, Horwitz, Gregory, Hou, Xiaomeng, Hu, Lijuan, Hu, Qiwen, Huang, Josh, Huo, Bingxing, Ito-Cole, Tony, Jacobs, Matthew, Jia, Xueyan, Jiang, Shengdian, Jiang, Tao, Jiang, Xiaolong, Jin, Xin, Jorstad, Nikolas, Kalmbach, Brian, Kancherla, Jayaram, Keene, Dirk, Kelly, Kathleen, Khajouei, Farzaneh, Kharchenko, Peter, Kim, Gukhan, Ko, Andrew, Kobak, Dmitry, Konwar, Kishori, Kramer, Daniel, Krienen, Fenna, Kroll, Matthew, Kuang, Xiuli, Kuo, Hsien-Chi, Lake, Blue, Larsen, Rachael, Lathia, Kanan, Laturnus, Sophie, Lee, Angus, Lee, Cheng-Ta, Lee, Kuo-Fen, Lein, Ed, Lesnar, Phil, Li, Anan, Li, Xiangning, Li, Xu, Li, Yang, Li, Yaoyao, Li, Yuanyuan, Lim, Byungkook, Linnarsson, Sten, Liu, Christine, Liu, Hanqing, Liu, Lijuan, Lucero, Jacinta, Luo, Chongyuan, Luo, Qingming, Macosko, Evan, Mahurkar, Anup, Martone, Maryann, Matho, Katherine, McCarroll, Steven, McCracken, Carrie, McMillen, Delissa, Miranda, Elanine, Mitra, Partha, Miyazaki, Paula, Mizrachi, Judith, Mok, Stephanie, Mukamel, Eran, Mulherkar, Shalaka, Nadaf, Naeem, Naeemi, Maitham, Narasimhan, Arun, Nery, Joseph, Ng, Lydia, Ngai, John, Nguyen, Thuc, Nickel, Lance, Nicovich, Philip, Niu, Sheng-Yong, Ntranos, Vasilis, Nunn, Michael, Olley, Dustin, Orvis, Joshua, Osteen, Julia, Osten, Pavel, Owen, Scott, Pachter, Lior, Palaniswamy, Ramesh, Palmer, Carter, Pang, Yan, Peng, Hanchuan, Pham, Thanh, Pinto-Duarte, Antonio, Plongthongkum, Nongluk, Poirion, Olivier, Preissl, Sebastian, Purdom, Elizabeth, Qu, Lei, Rashid, Mohammad, Reed, Nora, Regev, Aviv, Ren, Bing, Ren, Miao, Rimorin, Christine, Risso, Davide, Rivkin, Angeline, Muñoz-Castañeda, Rodrigo, Romanow, William, Ropelewski, Alexander, Roux de Bézieux, Hector, Ruan, Zongcai, Sandberg, Rickard, Savoia, Steven, Scala, Federico, Schor, Michael, Shen, Elise, Siletti, Kimberly, Smith, Jared, Smith, Kimberly, Somasundaram, Saroja, Song, Yuanyuan, Sorensen, Staci, Stafford, David, Street, Kelly, Sulc, Josef, Sunkin, Susan, Svensson, Valentine, Tan, Pengcheng, Tan, Zheng, Tasic, Bosiljka, Thompson, Carol, Tian, Wei, Tickle, Timothy, Tieu, Michael, Ting, Jonathan, Tolias, Andreas, Torkelson, Amy, Tung, Herman, Vaishnav, Eeshit, Van den Berge, Koen, van Velthoven, Cindy, Vanderburg, Charles, Veldman, Matthew, Vu, Minh, Wakeman, Wayne, Wang, Peng, Wang, Quanxin, Wang, Xinxin, Wang, Yimin, Wang, Yun, Welch, Joshua, White, Owen, Williams, Elora, Xie, Fangming, Xie, Peng, Xiong, Feng, Yang, William, Yanny, Anna, Yao, Zizhen, Yin, Lulu, Yu, Yang, Yuan, Jing, Z, Hongkui

Cellular Anatomy of the Mouse Primary Motor Cortex

2 Oct 2020 | bioRxiv
Muñoz-Castañeda, Rodrigo, Zingg, Brian, Matho, Katherine, Wang, Quanxin, Chen, Xiaoyin, Foster, Nicholas, Narasimhan, Arun, Li, Anan, Hirokawa, Karla, Huo, Bingxing, Bannerjee, Samik, Korobkova, Laura, Park, Chris, Park, Young-Gyun, Bienkowski, Michael, Chon, Uree, Wheeler, Diek, Li, Xiangning, Wang, Yun, Kelly, Kathleen, An, Xu, Attili, Sarojini, Bowman, Ian, Bludova, Anastasiia, Cetin, Ali, Ding, Liya, Drewes, Rhonda, D’Orazi, Florence, Elowsky, Corey, Fischer, Stephan, Galbavy, William, Gao, Lei, Gillis, Jesse, Groblewski, Peter, Gou, Lin, Hahn, Joel, Hatfield, Joshua, Hintiryan, Houri, Huang, Jason, Kondo, Hideki, Kuang, Xiuli, Lesnar, Philip, Li, Xu, Li, Yaoyao, Lin, Mengkuan, Liu, Lijuan, Lo, Darrick, Mizrachi, Judith, Mok, Stephanie, Naeemi, Maitham, Nicovich, Philip, Palaniswamy, Ramesh, Palmer, Jason, Qi, Xiaoli, Shen, Elise, Sun, Yu-Chi, Tao, Huizhong, Wakemen, Wayne, Wang, Yimin, Xie, Peng, Yao, Shenqin, Yuan, Jin, Zhu, Muye, Ng, Lydia, Zhang, Li, Lim, Byung, Hawrylycz, Michael, Gong, Hui, Gee, James, Kim, Yongsoo, Peng, Hanchuan, Chuang, Kwanghun, Yang, William, Luo, Qingming, Mitra, Partha, Zador, Anthony, Zeng, Hongkui, Ascoli, Giorgio, Huang, Josh, Osten, Pavel, Harris, Julie, Dong, Hong-Wei

Semantic segmentation of microscopic neuroanatomical data by combining topological priors with encoder-decoder deep networks

Oct 2020 | Nature Machine Intelligence | 2(10):585-+
Banerjee, Samik, Magee, Lucas, Wang, Dingkang, Li, Xu, Huo, Bing-Xing, Jayakumar, Jaikishan, Matho, Katherine, Lin, Meng-Kuan, Ram, Keerthi, Sivaprakasam, Mohanasankar, Huang, Josh, Wang, Yusu, Mitra, Partha

ZEBrA: Zebra finch Expression Brain Atlas-A resource for comparative molecular neuroanatomy and brain evolution studies

Aug 2020 | Journal of Comparative Neurology | 528(12):2099-2131
Lovell, P, Wirthlin, M, Kaser, T, Buckner, A, Carleton, J, Snider, B, McHugh, A, Tolpygo, A, Mitra, P, Mello, C

All Publications

The molecular cytoarchitecture of the adult mouse brain

Dec 2023 | Nature | 624(7991):333-342
Langlieb, Jonah, Sachdev, Nina, Balderrama, Karol, Nadaf, Naeem, Raj, Mukund, Murray, Evan, Webber, James, Vanderburg, Charles, Gazestani, Vahid, Tward, Daniel, Mezias, Chris, Li, Xu, Flowers, Katelyn, Cable, Dylan, Norton, Tabitha, Mitra, Partha, Chen, Fei, Macosko, Evan

AI without networks

9 Dec 2023 | bioRxiv
Mitra, Partha, Sire, Clément

Transcriptomic cytoarchitecture reveals principles of human neocortex organization

13 Oct 2023 | Science | 382(6667):eadf6812
Jorstad, Nikolas, Close, Jennie, Johansen, Nelson, Yanny, Anna, Barkan, Eliza, Travaglini, Kyle, Bertagnolli, Darren, Campos, Jazmin, Casper, Tamara, Crichton, Kirsten, Dee, Nick, Ding, Song-Lin, Gelfand, Emily, Goldy, Jeff, Hirschstein, Daniel, Kiick, Katelyn, Kroll, Matthew, Kunst, Michael, Lathia, Kanan, Long, Brian, Martin, Naomi, McMillen, Delissa, Pham, Trangthanh, Rimorin, Christine, Ruiz, Augustin, Shapovalova, Nadiya, Shehata, Soraya, Siletti, Kimberly, Somasundaram, Saroja, Sulc, Josef, Tieu, Michael, Torkelson, Amy, Tung, Herman, Callaway, Edward, Hof, Patrick, Keene, C, Levi, Boaz, Linnarsson, Sten, Mitra, Partha, Smith, Kimberly, Hodge, Rebecca, Bakken, Trygve, Lein, Ed

Wide field block face imaging using deep ultraviolet induced autofluorescence of the human brain

1 Sep 2023 | Journal of Neuroscience Methods | 397:109921
Karthik, Srinivasa, Joseph, Jayaraj, Jayakumar, Jaikishan, Manoj, Rahul, Shetty, Mahesh, Bota, Mihail, Verma, Richa, Mitra, Partha, Sivaprakasam, Mohanasankar

Full-Spectrum Neuronal Diversity and Stereotypy through Whole Brain Morphometry.

25 Jul 2023
Peng, Hanchuan, Liu, Yufeng, Jiang, Shengdian, Li, Yingxin, Zhao, Sujun, Yun, Zhixi, Zhao, Zuo-Han, Zhang, Lingli, Wang, Gaoyu, Chen, Xin, Manubens-Gil, Linus, Hang, Yuning, Garcia-Forn, Marta, Wang, Wei, De Rubeis, Silvia, Wu, Zhuhao, Osten, Pavel, Gong, Hui, Hawrylycz, Michael, Mitra, Partha, Dong, Hong-Wei, Luo, Qingming, Ascoli, Giorgio, Zeng, Hongkui, Liu, Lijuan

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