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Research Highlights

Hundreds of scientists working at Cold Spring Harbor Laboratory contribute research published in major research journals, in the fields of Cancer, Neuroscience, Plant Biology, Quantitative Biology, and Genomics.

Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly

9/21/2016

Researchers have uncovered a neural circuit that processes evaluations and have succeeded in identifying its sources. Read the story »

Revolutionary method to map the brain at single-neuron resolution is successfully demonstrated

8/19/2016

MAPseq can trace the long-range projections of large numbers of individual neurons from a specific region to wherever they lead in the brain. Read the story »

Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidants

7/28/2016

Researchers demonstrate that in the specific context of pancreatic cells leading to cancer, raisin antioxidant levels should not be raised. Read the story »

To divide or not: A cellular feedback loop that enables new cells to make a fateful decision

7/21/2016

Team explains a key mechanism to prevent aberrant cell proliferation Read the story »

Discovery of new ovarian cancer signaling hub points to target for limiting metastasis

7/10/2016

A team of researchers at Cold Spring Harbor Laboratory discovers new insights into signaling events that underlie metastasis in ovarian cancer cells. Read the story »

Discovery of new stem cell pathway indicates route to much higher yields in maize, staple crops

5/16/2016

Researchers discover a new regulatory pathway that channels signals emanating from a plant's extremities to the stem cell niche. Read the story »

Our brain uses statistics to calculate confidence, make decisions

5/4/2016

The brain produces feelings of confidence that inform decisions the same way statistics pulls patterns out of noisy data. Read the story »

Neanderthals mated with modern humans much earlier than previously thought, study finds

2/12/2016

Using several different methods of DNA analysis, an international research team has found what they consider to be strong evidence of interbreeding. Read the story »

Research connects specific variations in RNA splicing with breast cancer causation

10/1/2015

Researchers have identified cellular changes that may play a role in converting normal breast cells into tumors. Read the story »

What’s behind million-dollar crop failures in oil palm? Would you believe bad karma?

9/9/2015

A way to prevent damaged plantlets from being grown, to boost yield and reduce tropical land pressure. Read the story »

Mathematical ‘Gingko trees’ reveal mutations in single cells that characterize diseases

9/4/2015

Online app could help clinicians choose the best treatments by comparing genetic fingerprints of individual cells. Read the story »

Surprised? Cholinergic neurons send brain-wide broadcasts enabling us to learn from the unexpected

8/25/2015

Researchers find dedicated neurons that rapidly informing multiple subregions in the brain of any surprising rewards or punishments. Read the story »

In mice, an experimental drug treatment for Rett syndrome suggests the disorder is reversible

7/27/2015

A team at Cold Spring Harbor Laboratory find a new approach for treating Rett syndrome, a devastating autism spectrum disorder Read the story »

An immune system marker for therapy-resistant prostate cancer

6/4/2015

Research shows how signaling by an immune system component appears to play an important role in driving particularly aggressive prostate cancer Read the story »

Scientists pinpoint genes that make stem cells in plants, revealing origin of beefsteak tomatoes

5/25/2015

Researchers identified a set of genes that control stem cell production in tomato, which affects its size. Read the story »

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