Research Highlights

Hundreds of scientists working at Cold Spring Harbor Laboratory contribute research published in major research journals, in the fields of Cancer, Neuroscience, Plant Biology, Quantitative Biology, and Genomics.

CSHL team solves molecular structure of NMDA receptor subunit that could be target for drugs against neurological diseases

11/13/2009

A domain of the NR2B subunit of the NMDA receptor is mapped in exquisite detail. Read the story »

CSHL study shows that malignant tumors can be shut down after all

11/9/2009

Aggressive tumors lacking p53 protein stop dead in their tracks when p53’s sister protein—TAp63—steps in. Read the story »

Researchers identify drug candidate for treating spinal muscular atrophy

11/4/2009

A chemical cousin of the common antibiotic tetracycline might be useful in treating spinal muscular atrophy (SMA) Read the story »

CSHL scientists identify protein that enhances long-term memory by controlling rest periods

10/1/2009

Discovery could lead to treatments for learning and memory deficits, particularly Noonan’s syndrome Read the story »

Protein linked to mental retardation is found to control synapse maturation, plasticity by CSHL neuroscientists

6/1/2009

Oligophrenin-1, a Rho-GTPase-activating protein, stabilizes postsynaptic AMPA receptors Read the story »

Immunocytochemical analysis Aub AGO3 Piwi

CSHL scientists discover specific small RNA pathways protecting the germ line from genetic parasites

5/5/2009

In the fruit fly ovary, germ line and somatic cells use different piRNA pathways in transposon defense. Read the story »

CSHL team develops mouse models of leukemia that accurately predict response to chemotherapy

4/1/2009

p53 gene network is key determinant of response; its attenuation causes drug resistance. Read the story »

Scientists at CSHL discover mobile small RNAs that set up leaf patterning in plants

3/1/2009

Small RNAs act like morphogens in helping to define the boundary between the top and bottom sides of leaves Read the story »

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