Seungtai (Chris) Yoon

Seungtai (Chris) Yoon

Research Assistant Professor

Ph.D., Stony Brook University, 2006

yoon@cshl.edu | 516-367-5024

Genetics contribute to Autism in large degree. Modern genetics research demands an interdisciplinary approach to interpreting data generated from various high-throuput technologies. We are developing computational and statistical methods to analyze genomic data, with the goal of identifying mechanisms that cause genetic changes underlying autism.

Autism has been known for high heritability. Recently, high-throughput technologies such as microarray and next-generation sequencing enabled identification of de novo mutations associated with autism in simplex cohorts. Thus, the Yoon lab is working on finding de novo CNVs (Copy Number Variations) in higher resolution from sequencing data. Furthermore, causal mechanisms due to those mutations can be found by various approaches such as single-cell sequencing and RNA analysis. Thus, the Yoon lab is also analyzing data from these various platforms to explain genetic etiology of autism.

Building publication list.