CSHL Golf Tournament again raises nearly $700,000
News
Despite a rainy forecast, the event honoring CSHL Association Director Errol Kitt brought out more than 300 golfers and supporters. Read the story »
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CSHL Stories and Media
The Adenovirus Gazebo
Blog
It’s not just any gazebo—it’s a meeting place, a scenic overlook, and a monument to CSHL’s decades of revolutionary genetics research. Read the story »
A new body of knowledge
Get a guided tour of the world’s first hands-on cancer neuroscience course, and meet the scientists pioneering this new field of research. Watch the video »
Arkarup Banerjee named 2025 McKnight Scholar
News
The CSHL neuroscientist will receive $225,000 over three years for his lab's studies of the neural mechanisms underlying vocal communication. Read the story »
Cocktails & Chromosomes: Heresy in genetics
Imagine everything you learned about DNA wasn’t quite wrong, but was only a fraction of the truth. Now, get more of the whole story. Watch the video »
A recipe to reverse cancer’s sweet tooth
News
Researchers reveal the first 3D structures of the kinase FN3K in different states, which may inform future therapeutics for a variety of cancers. Read the story »
Exposomics: Holistic health without the snake oil
News
After gathering at Cold Spring Harbor Laboratory’s Banbury Center, the field’s leading minds issue a rallying cry heard across biology and medicine. Read the story »
Lessons learned in time: CSHL’s Symposium on aging
Look behind the scenes at the 89th CSHL Symposium and see some of science’s most brilliant minds share their insights on aging and senescence. Watch the video »
At the Lab: An evening out with the brain and body
Ever go to a neuroscience talk and wish it had more sound effects? Then this is the episode for you. Listen to the podcast »
A CSHL Symposium for the ages
News
We recap the 89th Cold Spring Harbor Laboratory Symposium on Quantitative Biology, which, for the first time, focused on aging and senescence. Read the story »
‘The bridge between hope and healing’
News
The Cosmopolitan Club hosts an inspiring event featuring CSHL Professor Alea Mills and Dr. John Boockvar of Netflix’s Lenox Hill and Emergency NYC. Read the story »
At the Lab: Catch me if you cancer
You’ve seen her on FOX and the cover of Newsday. Now, hear about the knowledge gaps that make her discovery so crucial and the noble goals driving it. Listen to the podcast »
President’s essay: We are science, and science is crucial
Feature
With public research funding under threat in the U.S., CSHL President Bruce Stillman outlines the stakes for people in our communities and abroad. Read the story »
Waltz of the Polypeptides
Blog
You need an electron microscope to see the birth of a protein anywhere else. At CSHL, it’s a short walk from Grace Auditorium—no microscope required. Read the story »
In nature’s math, freedoms are fundamental
News
CSHL quantitative biologists have developed a unified theory that could have countless applications, from plant breeding to drug discovery. Read the story »
At the Lab: The human Microprocessor
There’s a Microprocessor inside you. Actually, there are trillions. Only they’re not computer processors. They’re much smaller and far more complex. Listen to the podcast »
Cocktails & Chromosomes: Am I a neural network?
What are the core differences between AI and human intelligence? CSHL postdoc Ari Benjamin pulls back the curtain on today’s large language models. Watch the video »
At the Lab: AI evolves
CSHL neuroscientists discuss the biological brain’s multibillion-year advantage over AI—and the new algorithm they built based on that concept. Listen to the podcast »
Science and sustainability go hand in hand
Feature
At CSHL, the foundations for the future of bioscience are built on energy efficiency and environmental stewardship. What does that look like? Read the story »
Pancakes may never taste this good again
Blog
Graduate student Lucía Téllez Pérez reflects on her experience attending the recent CSHL meeting Cancer Genetics: History & Consequences. Read the story »
At the Lab: UTIs in women’s health
Why do breast cancer researchers focused on pregnancy start looking into urinary tract infections? The backstory is as intriguing as the story itself. Listen to the podcast »
CSHL to honor Chris Evert, Martina Navratilova & Bob Langer
News
Cold Spring Harbor Laboratory will host its 20th annual Double Helix Medals dinner on November 19 at the American Museum of Natural History. Read the story »
Sever named to TIME100 Health list
News
Sever is recognized for his leading role in establishing the independent, nonprofit openRxiv to ensure fast and free science communication worldwide. Read the story »
SBS awards honorary degree to accomplished biologist
Feature
James L. Manley is the Julian Clarence Levi Professor of Life Sciences at Columbia University and a leading expert in eukaryotic gene expression. Read the story »
CSHL celebrates SBS Class of 2025
News
The CSHL School of Biological Sciences conferred nine Ph.D.s and one honorary Doctor of Science degree during its 22nd commencement ceremony. Read the story »
At the Lab: The nuclear speckle option
Speckles sound innocent enough, like little spots. But don’t be fooled. These tiny structures could someday have big implications for cancer care. Listen to the podcast »
The CSHL School of Biological Sciences’ class of 2025
Feature
The School of Biological Sciences awarded Ph.D. degrees to nine students this year. Read some of their stories and reflections on their time at CSHL. Read the story »
Endometriosis Foundation of America commits $10 million to CSHL
News
EndoFound partners with CSHL to open the Seckin Endometriosis Research Center for Women’s Health at Cold Spring Harbor Laboratory. Read the story »
At the Lab: Dancing with fire
What happens to our brain receptors’ “dance routines” when the brain comes under immune system attack? Tune in to find out. Listen to the podcast »
Moses elected Fellow of Learned Society of Wales
News
The Welshman immigrated to the U.S. in 2020. He uses a revolutionary process called click chemistry to identify and test potential cancer treatments. Read the story »
Branching out: CSHL partners with LIAA to preserve grounds
News
Long Island Arboricultural Association volunteers gave CSHL and its historic 120-acre campus a spring refresh just in time for Arbor Day. Read the story »
At the Lab: Products of an unseen environment
You may have read about their fascinating research in
Lessons of the past, leaders of tomorrow
Feature
From March 26–29, CSHL’s Center for Humanities and History of Modern Biology hosted Cancer Genetics: History & Consequences. Read the story »
Cancer Genetics: History & Consequences
Hear from some of the field’s leading voices, including Mary-Claire King, Brian Druker, Stephen Elledge, and Nobel Prize winner Carol Greider. Watch the video »
Ludmila Pollock named AAAS Fellow
News
The CSHL Library & Archives leader was recognized for her efforts to promote humanistic understandings of modern biology and medicine. Read the story »
At the Lab: Science for lovers
You can’t spell evolution without l-o-v-e. A tale of passion and curiosity takes us from New York to Australia, France, the U.K., and South America. Listen to the podcast »
It’s not you—it’s cancer
News
CSHL Associate Professor Tobias Janowitz and colleagues discover the brain-body connection underlying apathy in the late stages of cancer. Read the story »
Cocktails & Chromosomes: Hormones on my mind
How do estrogen and testosterone influence mood, behavior, and health? CSHL neuroscientist Jessica Tollkuhn breaks it down for viewers young and old. Watch the video »
At the Lab: A vitamin for prostate cancer
For the Season 2 premiere of our podcast, we sit down with CSHL Professor Lloyd Trotman to discuss what could be a major breakthrough in men’s health. Listen to the podcast »
In pancreatic cancer, a race against time
News
By the time it’s diagnosed, it’s often too late. Now, Cold Spring Harbor Laboratory researchers have found a way to intercept the deadly disease. Read the story »
The food and fuel that farms itself
News
Duckweed can grow practically anywhere there’s sun and standing water. CSHL plant biologists identify the genes behind some of its most useful traits. Read the story »
Lucas Cheadle awarded $750K MIND Prize
News
Support from the Pershing Square Foundation empowers the CSHL neuroscientist to take a bold, new view of Alzheimer’s disease. Read the story »
Knowledge for life
CSHL School of Biological Sciences alumni look back on how their experiences prepared them for success in research, academia, and industry. Watch the video »
A perception quiz to blow your mind
Ready to think differently about how you see, smell, hear, taste, touch, and make sense of the world around you? Take the quiz »
CSHL holds first-ever cancer neuroscience course
News
How does one study the nervous system’s influence on cancer? They come to CSHL. The field is so new there hasn’t been any formal training—until now. Read the story »
Cocktails & Chromosomes: The hidden world inside our cells
What are nuclear speckles and how might these mysterious structures impact your DNA? Get an inside look from CSHL Assistant Professor Kate Alexander. Watch the video »
Anne Churchland donates $50K prize to CSHL student
News
The donation, made possible by the National Academy of Sciences, supports Zarmeena Dawood, a neuroscientist and M.D.-Ph.D. student in the Albeanu lab. Read the story »
The greatest challenge in the universe
Feature
How does the brain turn sensory information into world-building neural responses? New answers could open the door to AI-powered therapeutics. Read the story »
The other side of the harbor
Blog
Affordable, nearby, off-campus housing ensures CSHL’s young scientists can focus on pursuing lifesaving, world-changing research. Read the story »
The natural evolution of bioRxiv and medRxiv
News
Independent nonprofit openRxiv launches to secure the long-term sustainability of biomedical research–sharing platforms bioRxiv and medRxiv. Read the story »
Rohini Guin elected president of APSA
News
Guin, an M.D.-Ph.D. candidate in the Janowitz lab, will serve a three-year term on the student-led organization’s Executive Committee. Read the story »
CSHL and global collaborators map Solanum pan-genome
News
Landmark study carves a path for plant breeders to improve crops across the globe and expand the variety of produce available in grocery stores. Read the story »
Banerjee named NAS Kavli Fellow
News
The National Academy of Sciences selects CSHL Assistant Professor Ararkup Banerjee to participate in its annual Kavli Frontiers of Science Symposium. Read the story »
CSHL high schoolers named top Regeneron Scholars
News
CSHL volunteer Ishana Chadha and Partners for the Future participant Keita Takahashi are among the top student scientists in the U.S. Read the story »
Cocktails & Chromosomes: Where nature meets nurture
Cold Spring Harbor Laboratory neuroscientist Gabrielle Pouchelon puts a new spin on an age-old question during our first public science talk of 2025. Watch the video »
Aboff’s Paints donates $50K to CSHL breast cancer research
News
Assistant Professor Camila dos Santos and her colleagues in the CSHL Cancer Center thank the local family business for their continuing support. Read the story »
CSHL receives $100K for leukemia research
News
The Don Monti Memorial Research Foundation’s donation supports the Zhang lab’s ongoing research on several variants of the deadly blood cancer. Read the story »
Williams receives GSA Excellence in Education Award
News
CSHL’s Jason Williams joins a distinguished group of recipients honored for advancing science through teaching, mentoring, and public outreach. Read the story »
CRISPR manipulates plants’ flower powers
News
CSHL Professor Zachary Lippman and postdoc Amy Lanctot have discovered how similar fragments of DNA control flowering in distantly related plants. Read the story »
Deciphering brain diseases with click chemistry
Cold Spring Harbor Laboratory Professors John Moses and Hiro Furukawa speak at the CSHL Association’s 2025 Annual Meeting. Watch the video »
Ketamine: From club drug to antidepressant?
News
CSHL Professor Hiro Furukawa proves the existence of a mysterious brain receptor known as GluN1-2B-2D and shows how it may interact with ketamine. Read the story »
No Two Plants
News
CSHL postdoc’s experimental short film honors the legacy of Barbara McClintock, a continuing source of inspiration for women and girls in science. Read the story »
Statement on NIH funding guidance
News
New NIH Guidance will severely reduce funding for research. Supporting science is an investment in our nation’s health, security, and economy. Read the story »
‘Her dream continues’
News
A night of remembrance, a generous donation, and another step closer to a cancer-free world. Read the story »
Corn’s ancient ancestors are calling
News
Cold Spring Harbor Laboratory Professors Thomas Gingeras and Rob Martienssen have launched a new genomic encyclopedia called MaizeCODE. Read the story »
Nature is trying to tell you something
Feature
Former Cold Spring Harbor Laboratory scientist Richard Roberts won the Nobel Prize in 1993. Here, he recalls the “failure” that made him famous. Read the story »
‘Nuts & Bolts’ and ‘Midnight Fair’
Blog
That’s no moon! So what is it really? Read on to find out. Read the story »
A hearing aid for … your nose?
News
CSHL Professor Florin Albeanu and postdoc Diego Hernandez Trejo have found a feedback loop in the brain that may help us make sense of new sensations. Read the story »
Janowitz elected to ASCI
News
As a physician-scientist at CSHL, Tobias Janowitz has led early-phase clinical trials to develop therapeutic strategies for patients with cancer. Read the story »
A comeback story at Genes & Development
Feature
The acclaimed science journal, published by CSHL Press, has named molecular biologist Andrew Dillin as its new editor-in-chief. Read the story »
PSEG Long Island awards CSHL $279K in energy rebates
News
Cold Spring Harbor Laboratory’s sustainability initiatives reduce the institution’s operational costs while empowering high-tech research. Read the story »
‘Is cancer immunotherapy right for me?’
It’s a question that only you and your doctor can answer. Research from CSHL’s Peter Westcott may explain why it does or doesn’t work in some cases. Watch the video »
Cocktails & Chromosomes: Best shots of 2024
The popular CSHL event series returns to Industry Lounge on January 30, 2025. In the meantime, check out some highlights from last year’s talks. Watch the video »
From trading faxes to changing lives
Feature
In 1991, then-CSHL Investigator David Beach and future CSHL Trustee Charles Sherr made a serendipitous discovery. They’d each isolated the same gene. Read the story »
Check your prostate cancer knowledge today
Take this helpful quiz to find out about CSHL’s latest cutting-edge prostate cancer research. Take the quiz »
Are pro-oxidants anti-prostate cancer?
New research from CSHL Professor Lloyd Trotman offers men of all ages a look inside the possible future of prostate cancer treatment and prevention. Watch the video »
Mixed signals: How the brain interprets social cues
News
A new discovery from CSHL’s Shea lab helps explain how the brain processes multisensory information. It may have big implications for autism research. Read the story »
A speckle of hope for cancer patients
News
Research from new CSHL Assistant Professor Katherine Alexander suggests that nuclear speckles could influence kidney cancer patient outcomes. Read the story »
Eyes on the atom
Zoom in on the Nobel Prize-winning technology students in CSHL’s Cryo-EM Course use to study the structure and function of cells. Watch the video »
CSHL mourns the passing of Charles Dolan
News
His family’s name will forever be synonymous with public science education thanks to their transformational support of CSHL’s DNA Learning Center. Read the story »
The Firehouse
Blog
A lightly used Firehouse was one of the best gifts the Laboratory received in 1930. The only problem? It was on the wrong side of the harbor. Read the story »
The 2024 CSHL Volleyball Final
Eight teams entered the season on equal footing. Now, only two remain. But there can be only one champion. Press play to watch it all unfold. Watch the video »
Cocktails & Chromosomes: Cancer’s identity crisis
CSHL Professor Christopher Vakoc shares his research with a standing-room-only crowd at Industry bar in Huntington, NY. Watch the video »
Women’s lives, breast health, and cancer
A panel discussion featuring CSHL Associate Professor Camila dos Santos and three clinical professionals specializing in women’s health. Watch the video »
Big clues emerge in small RNA mystery
News
How does the body separate “self” from “nonself?” CSHL Professor Rob Martienssen uncovers fascinating new leads in plant pollen and mouse sperm. Read the story »
Lifesaving life science with Katalin Karikó
News
Watch the 2023 Nobel laureate speak about her life’s work with acclaimed popular science author Carl Zimmer. Read the story »
2024 Double Helix Medal recipient Dr. Katalin Karikó
She created the blueprint for mRNA vaccines. This year, Cold Spring Harbor Laboratory recognized her groundbreaking research and pioneering spirit. Watch the video »
Where are they now?
Feature
The CSHL School of Biological Sciences opened in 1999. Today, its graduates have become leaders in research, academia, and industry. Here’s how. Read the story »
Navlakha named Simons Foundation Pivot fellow
News
The computational biologist teams with CSHL’s Hannah Meyer to explore how the immune system solves problems also common in AI. Read the story »
2024 Double Helix Medal recipients Alisa & Daniel Doctoroff
The Doctoroffs lead Target ALS, an innovative nonprofit that has sparked dramatic progress in research on Lou Gehrig’s disease. Watch the video »
The Microprocessor inside you
News
Stunning new images from CSHL’s Joshua-Tor lab reveal how the protein complex interacts with differently shaped primary microRNAs. Read the story »
Frog Pond
Blog
These hopping amphibians aren’t the only animals that call the pond home. It’s a living snapshot of our area’s diverse ecosystem. Read the story »
The next evolution of AI begins with ours
News
How do innate abilities get passed down? Cold Spring Harbor neuroscientists have devised a solution that could lead to faster artificial intelligence. Read the story »
CSHL and Range ETFs launch new partnership
News
The affiliation was announced during a historic event at the Nasdaq stock market, highlighting the importance of cancer research. Read the story »
Cocktails & Chromosomes: Long-lived creatures of the night
Bat genes may hold the keys to aging, immunity, and cancer. Find out how, as we relive a special Halloween night event with CSHL’s Dick McCombie. Watch the video »
Empowering Insights: The science behind health
Feature
“The opportunity to turn curiosity into discoveries that impact the human condition is at the core of CSHL’s mission,” writes President Stillman. Read the story »
19th annual Double Helix Medals dinner raises $7 million
News
Cold Spring Harbor Laboratory’s annual gala honors Target ALS leaders Alisa and Daniel Doctoroff and Nobel laureate Dr. Katalin Karikó. Read the story »
The 2024 CSHL Raft Race
Ten teams brave cool harbor waters, the hot August sun, and new boat-building rules in the 9th annual CSHL Raft Race. Watch the video »
100 years of the Cold Spring Harbor Laboratory Association
Feature
A look back on the remarkable history of the group that helped turn Cold Spring Harbor, NY, into a leading destination for breakthrough bioscience. Read the story »
Flipping cancer’s off switch
News
CSHL Professor Christopher Vakoc and postdoc Olaf Klingbeil have found a potential drug target for some of the most common and deadly cancers. Read the story »
The 2024 CSHL Plate Race
The latest chapter in a decades-long rivalry unfolds, and a beloved Hammerhead shark returns. Watch the video »
New DNALC program aims to improve pandemic response
News
The federally funded initiative will train undergraduate teachers in disease-tracking techniques that could help prevent future pandemics. Read the story »
CSHL’s oldest haunts
Blog
These buildings have weathered oceans of time to be here. Pull back the veil and cross over into CSHL’s storied past for a closer look. Read the story »
At the Lab Season 1 Research Rewind: AI+
This season’s final Research Rewind brings us from the realm of quantitative biology to neuroscience, genomics, and beyond. Listen to the podcast »
New Jersey gets its first DNA Learning Center
News
A 6,500-square-foot research and education facility is housed in the Passaic County Technical Institute’s John Currie Biotechnology Innovation Center. Read the story »
Vitamin K supplement slows prostate cancer in mice
News
The finding from CSHL Professor Lloyd Trotman and his team sets the stage for pilot studies in human prostate cancer patients. Read the story »
Cocktails & Chromosomes: Barcoding, bugs, and brews
See Cold Spring Harbor Laboratory’s DNA Learning Center turn a crowd of bar patrons into citizen scientists. Watch the video »
At the Lab Season 1 Research Rewind: Genetics
It’s the code for all life on Earth. This week At the Lab, we’re hacking it with the help of Cold Spring Harbor Laboratory’s geneticists. Listen to the podcast »
Putting out a brain on fire
News
CSHL Professor Hiro Furukawa sheds new light on anti-NMDAR encephalitis, a rare autoimmune disorder that may be misdiagnosed as schizophrenia. Read the story »
Great minds think AI
News
Innovators and thought leaders in the fields of artificial intelligence and neuroscience came together for a meeting at Cold Spring Harbor Laboratory. Read the story »
At the Lab Season 1 Research Rewind: Neuroscience
What do you think? How do you know? And who are you anyway? We probe each of these questions with the help of Cold Spring Harbor’s neuroscientists. Listen to the podcast »
One Experiment: The brain’s landscapers
Feature
The brain relies on cells called OPCs to refine neural connections. CSHL’s Lucas Cheadle can now look at these synapse pruners in a whole new light. Read the story »
Adrian Krainer wins Albany Prize for biomedical research
News
A pioneer in the burgeoning field of RNA therapeutics, Krainer has now received America’s second-highest prize in medicine. Read the story »
At the Lab Season 1 Research Rewind: Cancer
As the first season of our new podcast winds down, we’re revisiting all of our episodes with a focus on CSHL’s cutting-edge cancer research. Listen to the podcast »
CSHL postdoc presents breakthrough autism findings
News
Irene Sanchez Martin’s research on prenatal inflammation’s role in autism is showcased at the Society for Neuroscience’s annual meeting. Read the story »
Plants have a backup plan
News
CSHL’s Rob Martienssen and his team discovered how plants like Arabidopsis continue to reproduce even when things go wrong in chromosome division. Read the story »
At the Lab Episode 26: The golden grail of genomics
For our Season 1 finale, we invite you to step inside EN-TEx, a catalog of more than one million genomic variants. Listen to the podcast »
NeuroAI with an eye on equity
Feature
Working at the intersection of neuroscience and computer science, CSHL researchers aim to build AI that will benefit everyone, not just the lucky few. Read the story »
Among the wildflowers
Blog
Colorful native flowers, courtesy of the Lab’s grounds crew and horticulturalists, attract both pollinators and people to CSHL’s seawall each day. Read the story »
How does cancer spread? Follow the map
News
CSHL Professor Adam Siepel and postdoc Armin Scheben use genetic barcodes to map how prostate cancer spreads. Read the story »
The curious immune cells caught between worlds
News
CSHL’s Hannah Meyer shows innate-like T cells mature differently in humans and mice. Her discovery could improve preclinical immunotherapy studies. Read the story »
At the Lab Episode 25: How maize became corn
Cold Spring Harbor Laboratory solves a plant biology mystery some 4,000 years in the making. The implications may go far beyond vegetables. Listen to the podcast »
CSHL grad student wins International Birnstiel Award
News
Shushan Toneyan won the award for her thesis research in CSHL’s Koo lab. Toneyan is the co-creator of CREME, an AI-powered virtual laboratory. Read the story »
Cocktails & Chromosomes: How the brain and body communicate
Hungry? How do you know? To answer questions like this, CSHL’s Jeremy Borniger taps into the circuits controlling brain-body communication. Watch the video »
At the Lab Episode 24: Putting the brakes on brain cancer
CSHL Professor Alea Mills compares the deadly brain cancer glioblastoma to a car with its brakes cut. Her lab works to reattach them. Listen to the podcast »
Is CREME AI’s answer to CRISPR?
News
CREME, the latest AI toolkit from CSHL, is a virtual laboratory that may help scientists find new therapeutic targets in the genome. Read the story »
New Library & Archives Chair established at CSHL
News
The Robert David Lion Gardiner Foundation establishes the Robert David Lion Gardiner Chair of Library & Archives at Cold Spring Harbor Laboratory. Read the story »
Making headlines
News
Several Cold Spring Harbor Laboratory faculty members received national mainstream media attention in 2024. Read the story »
At the Lab Episode 23: Cured with CRISPR
Victoria Gray, the first person ever cured of sickle cell, appeared on a DNA Learning Center panel featuring a clinical scientist from CSHL. Listen to the podcast »
The promise of genetics to cure disease
Victoria Gray was the first person cured of sickle cell disease with CRISPR gene-editing technology. Today, she shares her story. Watch the video »
At the Lab Episode 22: Outmuscling cancer
After 10 years, CSHL has made a breakthrough in the study of RMS, a rare pediatric cancer. How we got here is a story of innovation and perseverance. Listen to the podcast »
The nervous system’s matchmaker
News
CSHL’s Saket Navlakha has devised a new computer algorithm that could have many popular real-world applications. His inspiration: the nervous system. Read the story »
‘Earth Music III’
Blog
At 11 feet tall, this eye-catching artwork in CSHL’s Grace Auditorium is hard to miss. But what is it? Read the story »
How breast cancer goes hungry
News
CSHL Assistant Professor Michael Lukey has identified a source of breast cancer’s backup food supplies—and a way to block access. Read the story »
At the Lab Episode 21: Nature versus nurture
What makes you, you? CSHL Assistant Professor Gabrielle Pouchelon looks for answers in the brain’s earliest neural connections. Listen to the podcast »
Old chemo drug, new pancreatic cancer therapy?
News
CSHL scientists have found that folinic acid makes immunotherapy therapy more effective against pancreatic ductal adenocarcinoma in mice. Read the story »
Cocktails & Chromosomes: The whole-body health spectrum
How can a tiny tumor, often no larger than a penny, have such a big impact? CSHL’s Tobias Janowitz unpacks a complicated but highly relatable issue. Watch the video »
At the Lab Episode 20: Cleanup on IL-6
CSHL Professor Bo Li set out to study a tiny group of neurons involved in cancer cachexia. What he found astounded even him. Listen to the podcast »
Frogs: A biologist’s best friend
Get up close and personal with the exotic amphibian helping students in CSHL’s Xenopus course study how life begins and operates. Watch the video »
One Experiment: The devil in the greenhouse
Feature
CSHL’s meanest plant may help the Lippman lab tame prickly indigenous crops like Australia’s desert raisin. Read the story »
At the Lab Episode 19: Brain sex
How are sex differences defined in the brain? CSHL Associate Professor Jessica Tollkuhn delivers a thought-provoking primer on a fascinating topic. Listen to the podcast »
Science Meets Art at CSHL
News
Scientists, artists, and other luminaries came together for a summer festival celebrating CSHL’s Celia & Wally Gilbert Artist-in-Residence Program. Read the story »
Corn’s ‘missing link’
News
CSHL researchers have discovered a biological mechanism that may explain how corn spread so rapidly across the Americas 4,000 years ago. Read the story »
At the Lab Episode 18: The stress of cancer
A sobering conversation on a breakthrough discovery with potentially significant implications for cancer patients everywhere. Listen to the podcast »
Katherine Alexander joins CSHL cancer faculty
News
Her team will explore mysterious cellular structures known as nuclear speckles and their role in diseases such as cancer. Read the story »
Every rose has its thorns … or does it?
News
CSHL biologists have found a way to remove prickles from plants genetically. Their discovery could change the way we think about evolution in general. Read the story »
This protein does “The Twist”
News
CSHL Professor Hiro Furukawa has figured out how the NMDAR performs a key step in the brain’s cognitive dance. Read the story »
At the Lab Episode 17: AI SQUID
Tune in to this week’s podcast to hear about the latest artificial intelligence model coming out of Cold Spring Harbor Laboratory. Listen to the podcast »
Northern Lights shine over CSHL
Blog
The Aurora Borealis? At this time of year? In this part of the country? CSHL’s Arka Banerjee was on the scene to capture the dazzling display. Read the story »
At the Lab Episode 16: Bats!
Shriek if you must. Their remarkable genome might provide new insights into natural links between the immune system, aging, and cancer resistance. Listen to the podcast »
A century of women’s health breakthroughs
Feature
Oscar Riddle identified the hormone behind lactation in 1933. The discovery at CSHL continues to inspire research on women’s health and breast cancer. Read the story »
Cocktails & Chromosomes: Why do we age?
Humans have asked this question since the dawn of civilization. Today, we have the answer. Find out about this and more from CSHL’s Corina Amor Vegas. Watch the video »
Welcome to the summer of sequencing
News
CSHL’s DNA Learning Center and collaborators traveled cross-country to show educators the power of portable DNA sequencing. Read the story »
At the Lab Episode 15: Fruit flies’ dating lives
Can AI help us identify the Don Juan of fruit flies? CSHL’s Benjamin Cowley thinks so. Why would we want to do this? Tune in to find out. Listen to the podcast »
One Experiment: Brain-body’s feathery display
Feature
An angry peacock is no joke. Like the colorful bird and its tall tail feathers, cancer biology can make for some eye-catching images. Read the story »
The science behind Ozempic and Wegovy
Rockefeller University geneticist Jeffrey Friedman speaks about obesity’s causes and treatments at CSHL’s Brain-Body Physiology Symposium. Watch the video »
Recapping CSHL’s 88th Symposium
News
Thought leaders from around the world came together at CSHL to share and discuss the latest research in brain-body physiology. Read the story »
At the Lab Episode 14: What’s that smell?
You might not realize, but that question is central to the human experience. On this week’s podcast, CSHL’s Saket Navlakha sniffs out answers. Listen to the podcast »
How to stop cancer cachexia? Start at the top
News
Professor Bo Li and a team of collaborators from four CSHL labs have discovered a new potential drug target for the lethal wasting disease. Read the story »
CSHL’s 30th Annual Golf Tournament raises nearly $700,000
News
It was another record-breaker for the summer fundraiser, which this year honored Paul Paternoster, a longtime supporter of sarcoma research. Read the story »
At the Lab Episode 13: A more sustainable chemistry
For this week’s podcast, CSHL Professor John Moses bridges the gap between chemistry and biology in less than three minutes. Listen to the podcast »
Finding the sweet spot in brain development
News
Short-lived neural connections in the mouse brain can have long-lasting effects on how the animal senses and interacts with the world. Read the story »
CSHL to host first person cured of sickle cell
News
Join us July 13 at 1 p.m. for “Students Talk Science” with Victoria Gray, the first patient treated using CRISPR gene-editing technology. Read the story »
Table for 32
News
CSHL was excited to partner with Boy Scouts Troop 32 to help a young community member interested in science complete his Eagle Scout project. Read the story »
At the Lab Episode 12: Cancer cops
In this week’s podcast, CSHL Assistant Professor Semir Beyaz reveals how metastatic breast cancer ‘corrupts’ the body’s immune system. Listen to the podcast »
Catching Cancer When It’s Curable
CSHL Trustee Bruce Ratner discusses his new book during a fireside chat with Professor and Cancer Center Director David Tuveson. Watch the video »
SQUID pries open AI black box
News
CSHL’s Koo and Kinney labs have built a tool to suss out how AI analyzes the genome. What sets it apart? Decades of quantitative genetics knowledge. Read the story »
Can AI learn like us?
News
CSHL NeuroAI Scholar Kyle Daruwalla has created an AI neural network that can retain and recall knowledge much like we do. Read the story »
Pancreatic cancer’s cellular amnesia
News
New study from CSHL Professor Christopher Vakoc and former postdoc Diogo Maia-Silva shows how basal-like cancer cells lose their original identity. Read the story »
Barbara McClintock’s corn
Blog
You’ve heard about Barbara McClintock’s Nobel Prize-winning research on corn genetics, but what about the corn itself? Read the story »
Cocktails & Chromosomes: Of mice and moms
The latest installment in our public science talk series fell right between Mother’s Day and Father’s Day. CSHL’s Stephen Shea took it from there. Watch the video »
Wrexham University awards John Moses Honorary Fellowship
News
CSHL Professor John Moses returned to his hometown of Wrexham, Wales, where he was recognized for his contributions to science. Read the story »
At the Lab Episode 11: AI brainiacs
What is neuroAI, and how does it help both neuroscientists and computer scientists? In this week’s podcast, CSHL’s Kyle Daruwalla explains. Listen to the podcast »
RNA splicing’s spotters
News
RNA therapeutics pioneer CSHL Professor Adrian Krainer has discovered a link between two important regulator proteins, SRSF1 and DDX23. Read the story »
Meet Xenopus, the African clawed frog
News
Many popular technologies used in biology and medicine have froggy origins, and this CSHL course has helped keep the field hopping. Read the story »
At the Lab Episode 10: The time of our lives
“You wouldn’t start making the fingernails on an arm until you had started to make the arm,” says CSHL’s Christopher Hammell. How’s that for a visual? Listen to the podcast »
Mapping the mind with BARseq
News
CSHL Professor Anthony Zador’s powerful brain-mapping tool has received a major upgrade. Instead of thousands of neurons, it can now map millions. Read the story »
The Louise Lindsay Read paperbark maple
Blog
Like the Chinese maple outside Blackford Hall, the roots of CSHL’s broad intellectual family tree run deep. Read the story »
President’s essay: The continuous cycle of discovery
Feature
CSHL President & CEO Bruce Stillman discusses our institution’s societal impacts and global connections as forces for further scientific progress. Read the story »
At the Lab Episode 9: Musical mice
We put the ‘mice’ in ‘maestro,’ with singing lessons from Cold Spring Harbor Laboratory neuroscientist Arkarup Banerjee. Listen to the podcast »
New AI accurately predicts fly behavior
News
CSHL’s Benjamin Cowley trained an artificial intelligence model to predict how real-life fruit flies will act in response to specific visual stimuli. Read the story »
At the Lab Episode 8: Birds of a feather
How did some birds get such distinct colors? CSHL Professor Adam Siepel joins us for a journey across evolution’s “islands of differentiation.” Listen to the podcast »
Cocktails & Chromosomes: Immune cells’ brainy convos
CSHL Assistant Professor Lucas Cheadle invites you to listen in to the ongoing conversation between your immune system and your brain. Watch the video »
Autism genetics: The faces behind the data
Feature
CSHL research on autism involves massive databases with thousands of genomes. Meet a few of the brave individuals who help make this work possible. Read the story »
At the Lab Episode 7: Women in STEM
CSHL is no stranger to successful female scientists. Today, we remember the life of Martha Chase, famously known for the Hershey-Chase experiment. Listen to the podcast »
The Great North American Eclipse
CSHL faculty, students, and staff came together to witness one of the most breathtaking celestial events of our lifetime—a total solar eclipse. Watch the video »
On the passing of Jim Simons
News
We are saddened to share the passing of Jim Simons, a CSHL Honorary Trustee and one of our institution’s most significant supporters and donors. Read the story »
Tour CSHL’s Foundations for the Future project
Join New York Governor Kathy Hochul and CSHL President & CEO Bruce Stillman for an aerial tour of CSHL’s Foundations for the Future expansion project. Watch the video »
Governor Hochul announces $15 million for CSHL expansion
News
The funding will help pay for a new pancreatic cancer center—part of CSHL’s Foundations for the Future project. Read the story »
CSHL celebrates SBS Class of 2024
News
The CSHL School of Biological Sciences conferred 11 Ph.D.s and one honorary Doctor of Science degree during its 21st commencement ceremony. Read the story »
At the Lab Episode 6: Supermoms to the rescue
Happy almost Mother’s Day! What drives a supermom to come to the rescue when her child is upset? CSHL’s Stephen Shea shares the biological backstory. Listen to the podcast »
DNA Day at DNA Learning Center NYC
News
Community leaders from across New York came together in Brooklyn to celebrate CSHL’s achievements in making STEM education accessible for all. Read the story »
Senator Schumer visits DNA Learning Center NYC
Community leaders from across New York came together in Brooklyn to celebrate CSHL’s achievements in making STEM education accessible for all. Watch the video »
CSHL awards honorary degree to esteemed neurobiologist
Feature
The CSHL School of Biological Sciences awarded its honorary Doctor of Science degree to neuroscientist and geneticist Cori Bargmann Ph.D. Read the story »
The CSHL School of Biological Sciences’ class of 2024
Feature
The School of Biological Sciences awarded Ph.D. degrees to 11 students this year. Here are some stories and reflections from their time at CSHL. Read the story »
A link between breast changes and . . . UTIs?
News
CSHL breast cancer researchers, led by Associate Professor Camila dos Santos, made a surprise discovery while investigating urinary tract infections. Read the story »
At the Lab Episode 5: A heart of golf
A 500-year-old mystery stumbled on by Leonardo da Vinci has been solved using modern clinical data. Meet the CSHL scientist at the heart of it all. Listen to the podcast »
CSHL and Northwell Health extend strategic affiliation
News
Historic agreement aims to translate basic bioscience into a clinical setting, providing cancer patients greater access to personalized healthcare. Read the story »
Hazen Tower
Blog
The Italian-style bell tower anchors CSHL’s Neuroscience Center. Its bell has rung out every hour on the hour, from 8 a.m. to 8 p.m., since 1991. Read the story »
David Klindt joins CSHL neuroAI team
News
The new assistant professor will study how our brains navigate a continuously changing sensory environment: His goal: build more sensible AI. Read the story »
Tuveson elected to American Academy of Arts & Sciences
News
CSHL Cancer Center Director and Professor David Tuveson joins an elite membership roster whose historic ranks include names like Darwin and Einstein. Read the story »
At the Lab Episode 4: DNA sequencing for all
CSHL Dolan DNA Learning Center’s Jason Williams teaches us about a portable DNA sequencer that may turn the tide for genetics education. Listen to the podcast »
Environmental science’s Cold Spring Harbor origin
Feature
In 1929, Ruth Patrick came to CSHL to study plant life. She’d meet her future husband here and go on to pioneer an entirely new field of biology. Read the story »
Cocktails & Chromosomes: Through the eyes of a fruit fly
CSHL Assistant Professor Benjamin Cowley takes us inside the mind’s eye, using an AI model of this tiny insect’s brain. Watch the video »
Mitra Javadzadeh joins CSHL neuroscience faculty
News
Javadzadeh is the newest Cold Spring Harbor Laboratory fellow. Her lab studies how the brain processes visual information. Read the story »
At the Lab Episode 3: Autism Awareness Month
It’s Autism Awareness Month! CSHL Professor Ivan Iossofiv shares what researchers know about autism so far and how they plan to uncover its origins. Listen to the podcast »
Nobel laureate honored at CSHL chemistry symposium
News
“The Future of Click Chemistry” brought together two-time Nobelist K. Barry Sharpless with his former apprentices John Moses and David Tuveson. Read the story »
Up close and personal with cryo-EM
News
CSHL’s Cryo-Electron Microscopy course teaches the next generation of scientists to study life at the atomic level. Read the story »
At the Lab Episode 2: Molecular puppetry
CSHL neuroscientist Hiro Furukawa shows us a part of the brain that actually works like a puppet master. What could this mean for mental health? Listen to the podcast »
CSHL goes to the White House for Easter EGGucation
News
CSHL plant scientists taught kids the basics of plant biology and its role in the environment at an event hosted by First Lady Jill Biden. Read the story »
Click, click, boom—150 new molecules
News
CSHL Professor John Moses premieres an expansive line of new click chemistry products, uncovering leads for better antibiotics and cancer drugs. Read the story »
CSHL’s Thomas Gingeras awarded $2 million NSF grant
News
Climate change threatens crops with acidic soils and aluminum toxicity. Gingeras leads an international team tackling this problem head-on. Read the story »
At the Lab Episode 1: The tomato of tomorrow
In the premiere episode of At the Lab, we visit CSHL Professor & HHMI Investigator Zachary Lippman to glimpse the future of food and farming. Listen to the podcast »
Inside Jones Laboratory
Blog
Jones is CSHL’s oldest building. Since 1893, its exterior has remained virtually unchanged. Inside is a different story. Read the story »
One Experiment: Pancreatic mucus
Feature
That’s not the Starship Enterprise burning up in space. It’s an up-close look at precancerous pancreatic lesions and the mucus they produce. Read the story »
From plant genomics to a bioscience revolution
Feature
CSHL played a lead role in mapping the first plant genome. Today, that breakthrough fuels a whole new understanding of life on Earth. Read the story »
Better cancer trials could be around the corner
News
CSHL researchers have developed a new data-driven approach that cancer centers may use to expand patient recruitment efforts. Read the story »
Women’s health quiz
CSHL research has yielded insights into a number of women’s health topics, from menopause to breast cancer. Take this quiz to see how far we’ve come. Take the quiz »
New hope in the fight against neurofibromatosis
News
A partnership between CSHL and the Penny’s Flight Foundation aims to find a cure for NF1, the world’s most common single-gene neurological disorder. Read the story »
A call for support of trans scientists
News
CSHL Postdoctoral Fellow Simón(e) Sun has co-authored an article titled “Rigorous Science Demands Support of Transgender Scientists.” Read the story »
Cocktails & Chromosomes: Molecules to change the world
What is CSHL’s John Moses doing with that glowing liquid? Watch our expert chemist get a reaction from the crowd at Industry bar in Huntington, NY. Watch the video »
Alien language: CSHL returns to Cinema Arts Centre
News
March 26: CSHL neuroscientist Arkarup Banerjee discusses “Mysteries of Language & Communication” at a special screening of sci-fi blockbuster Arrival. Read the story »
Women in science on women’s health
Feature
CSHL’s Camila dos Santos and Jessica Tollkuhn offer empowering insights into breast cancer prevention, pregnancy, menopause, and hormone therapy. Read the story »
Why some RNA drugs work better than others
News
CSHL’s Justin Kinney and Spinraza inventor Adrian Krainer tested the newly approved SMA treatment, risdiplam, and another RNA therapeutic, branaplam. Read the story »
An evolutionary mystery 125 million years in the making
News
CSHL plant biologists have stumbled on a peculiar case involving a gene that’s key for controlling growth in tomatoes and other crops. Read the story »
Pancreatic cancer lives on mucus
News
Mucus is not just snot. CSHL scientists have discovered some pancreatic cancer cells depend on it. The finding may open a new therapeutic avenue. Read the story »
Can AI uncover breast cancer risk factors?
This question lies at the heart of a new interdisciplinary collaboration between CSHL’s Camila dos Santos and Peter Koo. Watch the video »
Chronic stress spreads cancer … here’s how
News
CSHL researchers have discovered a new link between chronic stress and cancer metastasis, providing a possible path forward for new treatments. Read the story »
‘Twisting Dendrites’
Blog
It’s not a sea creature. It’s in your brain. For over 20 years, this sculpture has inspired cutting-edge neuroscience research at CSHL. Read the story »
The immune system’s moonlighters
News
A tiny protein sequence with the potential to unlock new therapies against autoimmune diseases has been hiding in plain sight— until now. Read the story »
Cocktails & Chromosomes: Sequencing suds
CSHL’s series of fun, interactive science talks returns to Industry bar in Huntington, NY, with a demonstration of today’s DNA sequencing technology. Watch the video »
Pancreatic cancer hijacks a brain-building protein
News
CSHL researchers have found that EN-1, a protein involved in neurodevelopment, can help pancreatic cancer spread throughout the body. Read the story »
Genome sequencing for kids, one LEGO at a time
News
The CSHL DNA Learning Center’s LEGO DNA sequencer makes learning about the genome fun and easy for students of all ages, even kindergarteners. Read the story »
From novel discovery to anti-aging therapy
Feature
Former CSHL Fellow Carol Greider’s Nobel-winning research has led to new cancer treatments. Now, it’s helping us unravel the mysteries of aging. Read the story »
Angel’s Wish raises $45K for CSHL cancer research
News
The Christina Renna Foundation’s generous gift supports Professor Christopher Vakoc’s pioneering sarcoma research. Read the story »
CSHL PFF student named Regeneron scholar
News
Griffin Hon, a senior at Syosset High School, studied bowel disease alongside CSHL Assistant Professor Semir Beyaz using single-cell sequencing. Read the story »
How diet may impact cancer and possible treatments
Feature
Researchers at the CSHL Cancer Center study the links between disease and nutrition in hopes of uncovering new treatment and prevention strategies. Read the story »
How a mouse’s brain bends time
News
How does the brain govern communication? It’s all about timing. CSHL investigates with the help of a “musical” mouse from Costa Rica. Read the story »
A quiz for the ages
Want to know the secret to a long life? So do CSHL scientists. Take this short quiz to see what they’ve found out about aging and longevity. Take the quiz »
Bald eagles fight in flight
Blog
There’s been a surge of bald eagle sightings on campus. CSHL’s Vlad Drozdoff brings us an amazing close-up look at these birds in action. Read the story »
The fountain of youth is … a T cell?
News
CSHL's Corina Amor Vegas discovers that CAR T cells can act as a “living” drug, causing young mice to age more slowly and old mice to rejuvenate. Read the story »
One Experiment: The brain’s power lines
Feature
Everyone is “wired” differently. CSHL Associate Professor Jessica Tollkuhn maps the genes sex hormones use to shape developing brains. Read the story »
From cancer genetics to cancer treatments
Feature
One cancer gene, one cancer genome, two Cold Spring Harbor Laboratory discoveries that helped shape the face of modern cancer medicine. Read the story »
Cocktails & Chromosomes: Best shots of 2023
After a four-year hiatus, Cocktails & Chromosomes returned in 2023. Relive the past year’s best moments and see what’s in store for 2024. Watch the video »
Penicillin: From limited wonder drug to worldwide lifesaver
Feature
How Cold Spring Harbor Laboratory’s research on penicillin in the 1940s helped the U.S. win World War II and changed medicine forever. Read the story »
Where history connects
News
A recent workshop at the CSHL Library & Archives shed light on the interwoven histories of the Laboratory, Long Island, NY, and the greater U.S. Read the story »
COO Report: One for the record books
Feature
In 2023, Cold Spring Harbor Laboratory revenues achieved their second highest level ever. Read the story »
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