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Researchers identify gene behind spread of deadly breast cancer
News
Jackson Laboratory and Cold Spring Harbor Laboratory researchers uncovered novel targets for therapies related to deadly triple negative breast cancers. Read the story »
Making sense of the genome…at last
Feature
Quantitative biologists like Cold Spring Harbor Laboratory’s Adam Siepel are finally making sense of the flood of data contained in the human genome. Read the story »
The Lab partners with award-winning magazine
News
Nautilus, an award-winning science magazine, has partnered with CSHL to bring the story of the lab’s scientists and research to a brand-new audience. Read the story »
CSHL wins TD Ready Challenge grant for organoid facility
News
CSHL is one of the recipients of the TD Ready Challenge grant to help support the upcoming organoid facility. Read the story »
New trustees bolster CSHL board
News
Cold Spring Harbor Laboratory welcomes three new members to its Board of Trustees. Read the story »
Adrian Krainer wins 2019 Peter Speiser Award
News
Professor Adrian Krainer was awarded the Peter Speiser Award for advances in the pharmaceutical sciences. Read the story »
Nicholas Tonks named 2019 AAAS Fellow
News
CSHL Professor Nicholas Tonks is being honored as a 2019 AAAS Fellow for his work on signal transduction and the discovery of PTP. Read the story »
Fresh insights into prostate cancer surprise Movember crowd
Blog
For a special “Movember” edition of Cocktails and Chromosomes, Dr. Lloyd Trotman explained what his lab is doing to understand deadly prostate cancers. Read the story »
Movember with Lloyd Trotman—A Cocktails and Chromosomes talk about prostate cancer
In this Movember edition of Cocktails & Chromosomes, learn how new concepts of cancer evolution could turn prostate cancer into a curable disease. Watch the video »
Milestone reached in new leukemia drug
News
Salt-Inducible Kinase 3 (SIK3) could be a good therapeutic candidate for treating MLL translocation positive subtype of leukemia. Read the story »
The difference between an expert’s brain and a novice’s
News
Researchers use computational models to observe how changing neural activity can help mice learn new tasks and make better decisions. Read the story »
Research profile: Adam Siepel
Feature
Adam Siepel, Chair of the Simons Center for Quantitative Biology, uses advanced computational methods to solve complex biological questions. Read the story »
Vakoc wins Paul Marks Prize for cancer research
News
Professor Chris Vakoc was awarded The Paul Marks Prize for Cancer Research for his ongoing contributions to the understanding of cancer. Read the story »
14th annual Double Helix Medals dinner raises over $4 million
News
CSHL’s 2019 Double Helix Medals dinner honored the contributions of Dr. Nancy Wexler and Boomer Esiason. Read the story »
A home like no other, Cold Spring Harbor Laboratory
Hear why our campus, our community, and our collaborative nature makes us a place that so many scientists call "home." Watch the video »
Nancy Wexler, 2019 Double Helix Medal Recipient
For her contributions to basic research, Nancy Wexler was awarded a Double Helix Medal from Cold Spring Harbor Laboratory in 2019. Watch the video »
Scientists take action to prevent sexual harassment and bias
News
Scientists gathered at Banbury Center last year to discuss ways to prevent gender bias and sexual harassment in science. Read the story »
Boomer Esiason, 2019 Double Helix Medal Recipient
Cold Spring Harbor Laboratory awards Boomer Esiason a Double Helix Medal in 2019. Watch the video »
High school senior wins big in Breakthrough Junior Challenge
News
Winning the 2019 Breakthrough Junior Challenge, student Jeffery Chen earned his high school a $100,000 science lab designed by the DNA Learning Center. Read the story »
Historic lab at CSHL transformed for future cancer research
News
NY Governor Andrew Cuomo cut the ribbon for CSHL’s renovated Demerec lab space, marking the beginning of a new chapter for the historied building. Read the story »
CSHL named Top Long Island Workplace for second year
News
CSHL is named a Top Long Island Workplace by Newsday for the second year in a row. Read the story »
Researchers double sorghum grain number to improve food supply
News
A set of hormone-controlling genes may be the key to doubling grain number in sorghum plants. Read the story »
CSHL postdocs receive NARSAD Young Investigator Grants
News
Two CSHL neuroscience postdocs conducting neurobiological and psychiatric research received the 2019 NARSAD Young Investigators grant. Read the story »
The important role of an Uplands Farm cat
Blog
Cats, Uplands Farm’s smallest employees, have always played a big role in plant care and seed guarding. Read the story »
Nobel laureate William Kaelin draws a crowd
Blog
Nobel laureate and cancer researcher William Kaelin holds a seminar on his award-winning research at CSHL. Read the story »
Seeking better treatment for ALS, Lou Gehrig’s disease
News
Researchers found that ‘jumping genes’ were de-silenced in post-mortem tissue samples of ALS patients. Read the story »
Historic building—groundbreaking science
Feature
The Demerec building has been monumental in scientific history. Now, a $75 million renovation of this celebrated labspace will define CSHL’s future. Read the story »
One experiment: The shape of norovirus
Feature
Scientists at CSHL examine the structure of a norovirus under the cryo-electron microscope. Read the story »
Adrian Krainer elected to National Academy of Medicine
News
Professor Adrian Krainer joins the National Academy of Medicine in honor of his groundbreaking work on SMA. Read the story »
Learning about organoids at the CSHL Open House
Research Investigator Lindsey Baker, Ph.D., co-developed the organoid system for pancreatic cancer. In this video, she explains how it works. Watch the video »
BARseq builds a better brain map
News
Created by CSHL neuroscientists, BARseq is capable of mapping connections within a brain at single-neuron resolution while tracing their gene expression. Read the story »
Effective vaccines for Lyme disease are needed
News
A new report reiterates the need to stop Lyme disease and defines a strategy for developing effective vaccines against it. Read the story »
New brain research could change how concussions are treated
News
Blood vessel damage seems to be more widespread than nerve damage in patients with traumatic brain injuries. Read the story »
A new way to look at cancer with Tobias Janowitz—A Cocktails and Chromosomes talk
Given the errors that happen every time our cells divide, why don’t we get cancer all the time? Dr. Janowitz explained that and more over a beer. Watch the video »
Adrian Krainer wins Zülch Prize for lifesaving SMA Treatment
News
Professor Adrian Krainer is awarded the K-J. Zülch Prize for the development and testing of a first-of-its-kind treatment for spinal muscular atrophy. Read the story »
How Henri Termeer built a biotech giant
News
In a new biography out from CSHL Press, John Hawkins documents Henri Termeer’s legacy in biotechnology. Read the story »
Mutant cells team up to make an even deadlier blood cancer
News
Two very different mutations have been identified as unexpected partners-in-crime for causing the deadly blood cancer acute myeloid leukemia. Read the story »
Transparent review in preprints
News
Transparent Review in Preprints (TRiP) enables journals and peer review services to post peer reviews of manuscripts on CSHL’s preprint server bioRxiv. Read the story »
How to build more trust in science
News
Some of the world’s leading custodians of scientific research integrity met at CSHL’s Banbury Center to find out new ways to build trust in science. Read the story »
Coffee day quiz
Did you know that caffeine is a drug? On international coffee day, explore the chemistry of the infamous drink with our short science quiz. Take the quiz »
Discovery could improve MDS cancer treatment
News
Researchers have discovered a promising new target for treating myelodysplastic syndrome (MDS), a common and lethal blood cancer. Read the story »
Zachary Lippman named 2019 MacArthur Fellow
News
Cold Spring Harbor Laboratory Professor and HHMI Investigator Zachary Lippman has been named a 2019 MacArthur Fellow. Read the story »
Mice, like humans, fidget when deep in thought
News
Mice seemed to fidget while making decisions, prompting neuroscientists to think more about the connection between movement and cognition. Read the story »
Peter Koo wants to understand how machines learn biology
News
Dr. Peter Koo joins the CSHL faculty as an assistant professor. His focus is on exploring how artificial intelligence integrates with biology and genomics. Read the story »
Quiz gone viral
Since the Hershey and Chase experiment, scientists have expanded their understanding of viruses. Measure your viral knowledge with our science quiz! Take the quiz »
The next agricultural revolution is here
News
After reviewing decades of plant research, scientists suggest that with past lessons and modern tools, the next agricultural revolution is at hand. Read the story »
The world of Brianna Bibel, The Bumbling Biochemist
Blog
Brianna Bibel, a third-year graduate student at WSBS, is making ripples in the science community through her social media presence. Read the story »
How one family secured the future of a laboratory
Feature
The Robertson family gifts to CSHL in the early 1970s were of extraordinary importance, for without them the Laboratory might not have survived. Read the story »
Cancer drugs don’t always work as intended, researchers warn
News
Ten experimental cancer drugs kill tumors in ways that are entirely different than how clinicians thought they did, revealing important insights. Read the story »
Overcoming resistance in pancreatic cancer
News
Controlling pancreatic tumor proliferation by targeting malignancy-specific resistance pathways in response to AKT and MAPK blockade. Read the story »
Remembering David Koch
News
CSHL Board of Trustees, faculty and administration mourn the passing of David H. Koch, a supporter of cancer researcher. Read the story »
Are smart robots a threat?
News
In a Q&A, Neuroscientist Anthony Zador explains how neuroscience can inform machine learning, and why he’s not worried about a robot apocalypse. Read the story »
Understanding the animal brain could help robots wash your dishes
News
The field of machine learning still has a lot it can glean from neuroscience, especially in how evolution shapes an animal brain. Read the story »
New brain map could improve AI algorithms for machine vision
News
A revised view of the primate visual system may serve as a future reference for understanding how vision works in humans. Read the story »
CSHL graduate student wins HHMI fellowship
News
WSBS student David Johnson won a 2019 Gilliam Fellowships for Advanced Study for leadership and diversity in science. Read the story »
How a lab and its model animals changed science
Feature
The natural history of science at Cold Spring Harbor Laboratory through the lens of animal research. Read the story »
Understanding pregnancy’s effects on breast cancer risk
News
CSHL researchers authored a review in the journal Cell covering the landscape of breast cancer research. Read the story »
A survivor’s path to cancer research
Blog
Leukemia survivor and CSHL volunteer Anya Shah talks about her drive to do cancer research and her time in Vakoc lab. Read the story »
Creature feature quiz
Animals have been the muses behind major scientific breakthroughs for ages. See how much you know about the living organisms sharing the Earth with us. Take the quiz »
Of mice and model organisms
Feature
An in-depth look at how veterinarians at CSHL help take care of the various organisms that help researchers answer fundamental biological questions. Read the story »
Urban Barcode Project showcases student research in biodiversity
News
The eighth annual Urban Barcode Project Symposium had young scientists measuring the biodiversity of New York City. Read the story »
There’s more to smell than meets the nose
Feature
Neuroscience researchers work to figure out our brains process smells, including what features are essential to identifying and separating odors. Read the story »
Quantifying how the brain smells
News
Neuroscience researchers at CSHL are trying to figure out how the brain processes smells and what features of odors are important in that process. Read the story »
Discussing breast cancer with Camila dos Santos—A Cocktails and Chromosomes talk
Women who have their 1st child before age 25 are less likely to develop breast cancer later in life. Why? Dr dos Santos discusses finding the answer. Watch the video »
Sheltzer wins Presidential Early Career Award
News
CSHL Fellow Jason Sheltzer is a recipient of the Presidential Early Career Award for Scientists and Engineers for his work in cancer research. Read the story »
Laura Slatkin elected to CSHL Board of Trustees
News
Co-founder of NEXT for AUTISM Laura Slatkin joins the Cold Spring Harbor Laboratory Board of Trustees. Read the story »
Cancer cells’ “self eating” may be new drug target
Researchers reveal how pancreatic cancer cells adapt to the low energy environment of a tumor. Watch the video »
Cancer cell’s “self eating” tactic may be its weakness
News
Pancreatic cancer cells are eating their own mitochondria to survive and spread. New research reveals how, hinting at a possible new drug target. Read the story »
Diet and Disease
Are you what you eat? Two experts explain how nutrition can influence how your body responds to a range of cancer and other illness. Watch the video »
CSHL ranked #1 in research output worldwide
News
The scientific journal Nature named Cold Spring Harbor Laboratory as the top academic research institution in its annual index. Read the story »
Lee awarded Chan Zuckerberg Initiative Human Cell Atlas grant
News
Assistant Professor Je H. Lee has been named a recipient of one of the Seed Networks for the Human Cell Atlas to study breast tissue. Read the story »
Sugars that coat proteins are a possible drug target for pancreatitis
News
CA19-9, a complex sugar structure coating proteins, represents a possible drug target for treatment of pancreatitis and prevention of pancreatic cancer. Read the story »
Can these sugars serve as a possible drug target for pancreatitis?
CSHL Tuveson lab member Dani Engle explains how sugars serve as a possible drug target for pancreatitis. Watch the video »
2019 CSHL Open House was a hit!
News
Over 650 neighbors and science enthusiasts visited the 2019 Open House at CSHL. Read the story »
Special fibroblasts help pancreatic cancer cells evade immune detection
News
Researchers found a specific type of cancer-associated fibroblast interacts with the immune system to help pancreatic cancer cells stay under the radar. Read the story »
Cryo-EM illuminates intricate designs of noroviruses
Feature
Researchers reconstruct four different strains of the food-poisoning causing norovirus using the groundbreaking cryo-electron microscope. Read the story »
Norovirus structures could help develop treatments for food poisoning
News
Researchers at CSHL used cryo-EM to reconstruct the structures of four different strains of human noroviruses, which cause food poisoning. Read the story »
Fighting cancer in 3D
News
David Tuveson, Director of the CSHL Cancer Center, shares insights about his work on organoid technology. Read the story »
New preprint server for the health sciences announced today
News
CSHL, Yale University, and BMJ launch medRxiv, a free preprint service for the medical and health sciences. Read the story »
Plan Universal calls on funders to encourage preprints
News
bioRxiv founders propose new plan to encourage organizations to make research readily available via preprint servers. Read the story »
Interview with a neuroscientist
Feature
CSHL Professor Bo Li’s lab studies the biology behind mental disorders. Learn more about how Li’s work is changing the way we think about mental health. Read the story »
Building a song: A look at CSHL’s Choir
Hard practice pays off. CSHL’s choir performs the WSBS alma mater, while we look at the community they’ve built around music. Watch the video »
Hitting the high notes at the Lab
Blog
The CSHL choir is a cherished tradition, bringing song to some of the Lab’s most important occasions. Learn more about the history of this storied group. Read the story »
CSHL celebrates 20 years of graduate school at 2019 commencement
News
The Watson School of Biological Sciences held its 16th commencement, with seven researchers graduating with doctoral degrees. Read the story »
Leading discovery
Feature
Current discoveries about DNA and human genome position CSHL scientists to make life-changing breakthroughs that will improve the human condition. Read the story »
Honorary degrees to former CSHL leaders
News
From pioneering eukaryotic gene regulation to directing cancer research, here are the alumni being awarded honorary Doctor of Science degrees. Read the story »
Watson School alumni spotlights
News
This year, Watson School celebrates the 20th anniversary of its first entering class and looks back at some notable alumni from over the years. Read the story »
Watson School 2019 Ph.D.s
News
Seven students were awarded Ph.D. degrees from Watson School this May. Here, they reflect on their time at the Laboratory as they look to the future. Read the story »
An essay from the President: Biology for the planet
Feature
CSHL plant scientists are looking for solutions to the biggest questions in agriculture as environments are reshaped by climate change. Read the story »
Enzyme PHLPP2 could be a viable drug target for treating prostate cancer
News
Researchers have identified an enzyme called Phlpp2 as an attractive drug target for treating prostate cancer. Read the story »
Remembering John Cairns, CSHL Director, 1963-1968
News
CSHL celebrates the achievements of the late Dr. John Cairns, lab director from 1963 to 1968. Read the story »
Profile: Doreen Ware champions the plant genome
Feature
Molecular biologist Doreen Ware uses computer science to parse out the genetic roadmaps of plants. Read the story »
Cryptic mutation is cautionary tale for crop gene editing
Feature
Unexpected interactions between mutations can be a thorn in the side for plant breeders. Scientists unveil what drove one infamous “cryptic” mutation. Read the story »
How do plants sense their environment?
CSHL plant scientist Ullas Pedmale details how plants sense the world we share. Watch the video »
Andrea Schorn zooms in on small RNAs in the cell
News
Dr. Andrea Schorn joins CSHL faculty as research assistant professor. Her focus is exploring transposable elements in the genome of mammalian cells. Read the story »
DNA and pop culture quiz
When artistic expression meets gene expression, how well does art imitate life? Take our five-question science IQ quiz to find out. Take the quiz »
Seeing with sequencing—A public lecture with three CSHL experts
Quantitative biologists discuss how physics, modern computing power, and a new perspective on biology can make sense of our complex genomes. Watch the video »
Cold Spring Harbor Laboratory announces exclusive license with plant breeding start-up Inari
News
CSHL announced a licensing agreement with partner Inari, a company that is advancing plant breeding by tapping nature’s genetic diversity. Read the story »
Rob Martienssen wins Martin Gibbs Medal for plant research
News
CSHL Professor Rob Martienssen wins the 2019 Martin Gibbs Medal for his contributions to plant biology. Read the story »
To protect stem cells, plants have diverse genetic backup plans
News
Experts discover how an essential genetic circuit found in all flowering plants, regardless of species, is protected in startlingly different ways. Read the story »
NIH grant awarded for interneuron research
News
CSHL postdoc Maggie Crow will use her NIH grant to pursue the quantification and analysis of specific types of neurons in the brain. Read the story »
President Bruce Stillman wins prestigious Gairdner Award
News
Dr. Bruce Stillman, President & CEO of CSHL, has been awarded the 2019 Canada Gairdner International Award for his work on eukaryotic DNA replication. Read the story »
Crop yield in maize influenced by unexpected gene ‘moonlighting’
News
Yield of the maize plant is tied to activity of a gene called RAMOSA3, but new evidence suggests the gene performs other unexpected functions Read the story »
Hannah Meyer joins CSHL Quantitative Biology faculty
News
Hannah Meyer is the newest Quantitative Biology Fellow at CSHL, studying how our immune system learns to identify and fight pathogens. Read the story »
CSHL President elected as AACR Academy Fellow
News
CSHL President and CEO Dr. Bruce Stillman has been elected to the AACR Academy as part of the 2019 Fellows class. Read the story »
One experiment: Observing cancer’s progress in a mouse prostate
Feature
Using a technique originally designed for mapping brains, two CSHL labs have worked together to image cancer progression in a mouse prostate. Read the story »
Banbury meeting addresses neurotechnology concerns
News
A white paper written after an important Banbury Center meeting discusses the lack of oversight in direct-to-consumer neurotechnologies. Read the story »
New cell subtypes classified in mouse brain
News
To map a brain, an intuitive system for classifying neuron types is necessary. Now, a promising approach reveals new cell subtypes in the mouse brain. Read the story »
Adrian Krainer wins RNA Society’s Lifetime Achievement Award
News
Professor Adrian Krainer was awarded the RNA Society’s Lifetime Achievement Award for his life-saving research. Read the story »
Congressman Suozzi congratulates CSHL Partner for the Future
News
Partner for the Future Pragati Muthukumar received a special commendation from Congressman Tom Suozzi. Read the story »
Genetic ‘usual suspects’ identified in researchers’ new list
News
An exhaustive ranked list of “usual suspect” genes involved in disease may prove invaluable for future research and drug discovery. Read the story »
Chandelier neuron requires ‘Velcro-like’ molecule to form connections
News
How do brain cells network? Researchers have discovered an essential ingredient that facilitates one type of neuron’s many neighborly connections. Read the story »
Detailed new primate brain atlas could lead to disease insights
News
An international effort has mapped the marmoset brain at an unprecedented level of detail, which brings us closer to understanding the human brain. Read the story »
Science is a lesson in ‘eye-opening’ for students and teachers
Blog
WSBS graduate student Bruno Gegenhuber embraced teaching at the DNA Learning Center as a learning experience in itself. Read the story »
What does sight mean to a cancer researcher?
Blog
Postdoc Leah Banks discusses vision’s role in cancer research, and how nearly losing her sight gave her a new perspective on her work. Read the story »
David McCandlish named Sloan Research Fellow
News
Assistant Professor David McCandlish has been named a 2019 Sloan Research Fellow for his promising work in the field of quantitative biology. Read the story »
bioRxiv surpasses one million monthly downloads
News
A recent study illustrates the success of bioRxiv, CSHL’s biology preprint server. Read the story »
Christina Renna Foundation gives $35k for pediatric cancer research
News
The Christina Renna Foundation donated $35,000 to CSHL for continued work on Sarcoma Research Project and research into RMS. Read the story »
CSHL Scientific Advisory Council member wins Vilcek Prize
News
Dr. Angelika Amon, a member of the CSHL Scientific Advisory Council, wins the Vilcek Foundation Prize for her important work in cell biology. Read the story »
How does math help us understand the brain?
Feature
An exploration of how computational neuroscientist Tatiana Engel uses math to understand how the brain makes decisions. Read the story »
CSHL Fellow Jason Sheltzer wins innovation award
News
CSHL Fellow Jason Sheltzer wins the Damon Runyon-Rachleff Innovation Award for his work on cancer. Read the story »
CSHL Scientific Advisory Council member wins NAS honor
News
Dr. Eve Marder of the CSHL Scientific Advisory Council wins the National Academy of Sciences Award in the Neurosciences. Read the story »
Rob Martienssen special talk: Barbara McClintock’s Controlling Elements, Then and Now
Rob Martienssen's special lecture on Barbara McClintock's 'Controlling Elements, Then and Now,' given at the CSHL Library Szybalski Reading Room. Watch the video »
Rethinking cancer medicine
Tobias Janowitz, M.D., Ph.D. presents “how tumors interact with the entire body” and how understanding this, leads to “the questions that matter.” Watch the video »
CSHL donates sheets to veterans in need
News
CSHL donated 75 bags of sheets to the United Veterans Beacon House, with the aid of the Lindenhurst Rotary Club and the Christina Renna Foundation. Read the story »
Targeting ‘hidden pocket’ for treatment of stroke and seizure
News
Researchers have identified a hidden molecular “pocket” in a special neuron receptor, which could lead to better treatments for stroke and seizures. Read the story »
Austin’s Purpose donates $10k to neuroscience research
News
Epilepsy research-supporting organization Austin’s Purpose makes a donation to continue key neuroscience research in Professor Hiro Furukawa’s lab. Read the story »
Statement by Cold Spring Harbor Laboratory addressing remarks by Dr. James D. Watson in “American Masters: Decoding Watson”
News
Statement by Cold Spring Harbor Laboratory addressing remarks by Dr. James D. Watson in “American Masters: Decoding Watson.” Read the story »
Reflecting on progress for women in STEM
Nancy Hopkins, Professor of Biology emerita, MIT, spent an afternoon at CSHL discussing the progress of women's rights and gender equality in science. Watch the video »
The year of CRISPR
Feature
A look at the various labs across CSHL that utilize CRISPR in their research, and the groundbreaking discoveries they help uncover. Read the story »
How does natural selection affect the genome?
Adam Siepel explains how natural selection can tell researchers how informative sifting through the complex human genome will be. Watch the video »
How much are we learning? Natural selection is science’s best critic
News
Researchers determine that natural selection and our evolutionary history may be the best guides for future research. Read the story »
Larry Norton—2018 Double Helix Medal recipient
Here is why CSHL so deeply admires and appreciates 2018 CSHL Double Helix Medal recipient, Larry Norton, M.D. Watch the video »
Taking uncertainty out of cancer prognosis
An analysis of 20,000 patients has revealed that copy number variations in specific gene sites can help predict how deadly a cancer will be. Watch the video »
Taking uncertainty out of cancer prognosis
News
CSHL Fellow Jason Sheltzer has analyzed nearly 20,000 cancer patient histories and genetic data to take the guesswork out of prognosis. Read the story »
National Academy of Inventors Fellow, Adrian Krainer
News
Professor Adrian Krainer has been named a NAI 2018 Fellow for his work on the first FDA-approved treatment for spinal muscular atrophy. Read the story »
Big bold dreamers
Feature
Dreamers drive discoveries. CSHL honors its many scientists making big impacts in their respective fields. Read the story »
Marilyn Simons elected Cold Spring Harbor Laboratory chair
News
Dr. Marilyn Simons becomes the chair of the CSHL Board of Trustees, new officers are elected, and three new trustees join the board. Read the story »
Breakthrough Prize laureates meet at CSHL
News
Breakthrough Prize winner Adrian Krainer & C. Frank Bennett reunite for the first time since their award ceremony at CSHL to discuss further project. Read the story »
Molly Hammell wins CZI award for ALS study
News
Associate Professor Molly Hammell wins award for proposed study to find transposable elements that are implicated in ALS. Read the story »
How the brain hears and fears
News
Researchers are studying how the brain reacts to sounds that it associates with fear, and how easy it is for the brain to learn and unlearn. Read the story »
Inconspicuous protein key to deadly blood cancer
Researchers have revealed the remarkably common protein behind an aggressive blood cancer’s drivers. By taking it away, the disease collapses. Watch the video »
Inconspicuous protein key to deadly blood cancer
News
Associate Professor Chris Vakoc and his team find that an aggressive type of leukemia is heavily-dependent on a common protein. Read the story »
AAAS names two CSHL faculty as 2018 Fellows
News
David Jackson and Jan A. Witkowski were both named 2018 AAAS Fellows for their work in the fields of agriculture and biology. Read the story »
Pancreatic cancer’s addiction could be its end
Researchers have discovered that an inappropriately-produced protein may be why some pancreatic cancer patients die exceptionally early. Watch the video »
Pancreatic cancer’s addiction could be its end
News
Researchers may have found a link between improper protein production and the spread of pancreatic cancer. Read the story »
13th Double Helix Medals dinner raises over $4 million
News
Dr. Priscilla Chan, Mark Zuckerberg, and Dr. Larry Norton were honored for their contributions to basic research at the Double Helix Medals dinner. Read the story »
Turning cells against pancreatic cancer
Researchers have identified the special signals that encourage normal cells to either help protect pancreatic cancer, or—ideally—hinder it. Watch the video »
From many mice, unexpected genius
A massive study of mouse behavior has revealed that some individual animals are far more clever than studying only a small group might imply. Watch the video »
A great place to work!
News
CSHL is named a 2018 Top Long Island Workplace by Newsday through the use of employee surveys. Read the story »
From many mice, unexpected genius
News
Researchers find that some individual mice are smarter than their fellow rodents, which can provide insights into decision-making. Read the story »
Thanks, National Grid Foundation for hands-on science!
News
The DNA Learning Center has completed the National Grid Advanced Genetics Program (NGAGP) in the Central Islip school district. Read the story »
Turning cells against pancreatic cancer
News
Researchers have found a way to turn cancer-supporting cells into cells that restrict the cancerous growth in the pancreas. Read the story »
New regulators of nitrogen use in plants identified
News
A team of CSHL plant biologists identify gene regulators that may help plants utilize nitrogen better and prevent excess nitrogen in soil. Read the story »
Genetic privacy: A friend or foe?
How concerned should you be about keeping your DNA private? Watch the video »
Adrian Krainer, ganador del Breakthough Prize
Profesor Adrian Krainer desarrolló un tratamiento para la Atrofia Muscular Espinal. Por su trabajo, recibió el prestigioso el Breakthrough Prize. Watch the video »
The big problem of small data: A new approach
News
You’ve heard of “big data” but what about small? Researches have crafted a modern approach that could solve a decades-old problem in statistics. Read the story »
The hope of a Breakthough Prize Winner
Professor Adrian Krainer describes the hope he fulfilled with the development of the first effective therapy for the neurodegenerative disease SMA. Watch the video »
Breakthrough Prize to CSHL professor for SMA research
Professor Adrian Krainer recently received the 2019 Breakthrough Prize in Life Sciences for the development of a life-saving treatment for SMA. Watch the video »
Breakthrough Prize to CSHL professor for SMA research
News
Professor Adrian Krainer has received a Breakthrough Prize in Life Sciences for his work on the first FDA-approved treatment of SMA. Read the story »
Base Pairs Episode 17.5: Special interview with Yaniv Erlich
We sat down with Dr. Yaniv Erlich, chief scientific officer at MyHeritage DNA, to get his unique perspective on the use of personal genetic info. Listen to the podcast »
Cancer research from a different perspective
News
CSHL Assistant Professor Tobias Janowitz discusses his patient-centric approach to studying cancer Read the story »
What’s that smell? Neuroscientists are figuring it out
News
Neuroscientists Florin Albeanu and Alexei Koulakov win the NIH Director’s Transformative Research Award for their project on the olfactory system. Read the story »
CRISPR could bring groundcherries to market
News
CSHL Professor Zachary Lippman uses CRISPR to make the groundcherry more suitable for large-scale farming Read the story »
Computational neuroscientist wins BRAIN grant
News
Assistant Professor Tatiana Engel earns grant to build tools that will help build better models of the brain Read the story »
CSHL podcast wins prestigious PR News award
News
CSHL’s Base Pairs podcast wins the Platinum PR Award for Best Podcast from PR News Read the story »
How a sleeping cancer awakens and metastasizes
News
Chronic inflammation can reawaken dormant cancer cells and spur metastasis. It may be preventable Read the story »
Future scientists take to the bench
News
The latest class of the Partners for the Future program visit the Lab and meet their mentors as they get to work Read the story »
Base Pairs Episode 17: Genomes, justice, and the journey here
A look at how gene-mapping works, what scientists can tell by looking at your genome, and what it means for your privacy. Listen to the podcast »
Genomes, justice, and the journey here
Feature
CSHL Professor W. Richard McCombie discusses genomic privacy and sequencing technology in this episode of Base Pairs. Read the story »
Path to cancer in the brain set by protein CHD5
News
Researchers find that protein keeps neural stem cells from activating too soon and hindering brain development Read the story »
From workshops to lab work—right next door
Blog
College student James Korossy’s journey from taking workshops at the DNA Learning Center to working at the bench in CSHL Fellow Lingbo Zhang’s lab. Read the story »
Predicting how splicing errors impact disease risk
News
New research helps correlate genetic mutations with errors in RNA splicing that can cause serious illness Read the story »
CSHL team wins scientific case competition
News
Five CSHL postdocs and graduate students won first place at the fifth annual Tufts New England Case Competition (TUNECC). Read the story »
CSHL helps ring opening bell at Nasdaq
News
CSHL Professor Adrian Krainer and his team join the Spinal Muscular Atrophy (SMA) Foundation in ringing the Nasdaq opening bell Read the story »
Undergrad symposium highlights lessons in the lab
News
The 2018 Undergraduate Research Program class presents their projects after working for ten weeks in various labs across campus. Read the story »
What does it mean to be an URP?
A quick chat with a student and his mentor reveals how much the work of our undergraduate researchers mean to CSHL. Hint: A whole lot. Watch the video »
The miracle of brain development
Feature
In a series of 8 stunning images, CSHL scientists enable us to share the miracle of a brain as it self-assembles Read the story »
One experiment: Building a brain
Feature
A genetic program precisely guides development of a part of the brain Read the story »
Base Pairs Episode 16.5: Fuels of the fuels
Rob Martienssen explains how genetic modification and advances in technology factor into the future of fuel as well as cinematic sci-fi fuels. Listen to the podcast »
Dr. Zador wins Transformative Investigator award
News
CSHL professor Anthony Zador wins Gill Symposium prize for his innovative work on MAPseq Read the story »
Possible treatment for Wilson’s disease unexpectedly identified
Dr. Nicholas Tonks describes how the serendipity inherent to basic research played its part in discovering a potential treatment for Wilson's disease. Watch the video »
Seeding citizen science with DNA barcoding
News
Teachers trained in DNA barcoding can mentor students as they become citizen scientists investigating what interests them most. Read the story »
Base Pairs Episode 16: Big plans for a tiny plant
As temperatures around the globe continue to rise, scientists are working hard to develop solutions that deal with the consequences of climate change Listen to the podcast »
Big plans for a tiny plant
Feature
On this episode of Base Pairs, Rob Martienssen discusses how duckweed could be the next biofuel and help combat climate change Read the story »
Massive genome havoc in breast cancer is revealed
News
Researchers have made a highly detailed map of 20,000 structural variations in a cancer cell’s genome Read the story »
CSHL Fellow Semir Beyaz wins three awards
News
Semir Beyaz has won three awards for his research on the impact of dietary choices on the body’s immunity against cancer Read the story »
Nicholas Tonks wins prestigious ASBMB award
News
Professor Nicholas Tonks wins Earl and Thressa Stadtman Distinguished Scientist Award from the American Society for Biochemistry and Molecular Biology Read the story »
CSHL spinoff wins investment prize
News
CSHL spinoff company MapNeuro Inc., which uses tech developed in Zador lab, wins 2018 Seed Capital Prize from Alexandria LaunchLabs Read the story »
Researchers discover new type of lung cancer
In discovering a new form of small cell lung cancer, a research team at CSHL has identified a potential target for personalized treatments. Watch the video »
Progress toward improved Wilson’s disease drug
News
Encouraging early results in a potential new treatment for Wilson's disease. Read the story »
Researchers discover new type of lung cancer
News
Researchers have discovered a new form of lung cancer. Read the story »
Postdoc wins Indian National Science Academy prize
News
Dhananjay Huilgol, a postdoc in Professor Joshua Huang’s lab, wins one of India’s highest honors for young investigators Read the story »
Metastasis & immunity
How immune cells can help cancer spread, or stop it in its tracks—A free Public Lecture featuring Mikala Egeblad, Ph.D. and Sylvia Adams, M.D. Watch the video »
Base Pairs Episode 15.5: Cellular hide and seek
Learn how William Coley's daughter founded the Cancer Research Institute, Professor Fearon on the immune system, and white blood cells on screen. Listen to the podcast »
Energy from thin air: Basic research to biofuels
A plant scientist and an industry innovator discuss how simple duckweed may help address climate change and energy needs. Watch the video »
Being a scientist means being part of a team
Blog
High school senior Jerinna Solages learns what it’s really like to do scientific research in CSHL’s Partners for the Future program. Read the story »
The case for open and inclusive science
Feature
America must continue to a place where the most talented people in the world want to live, study and work. Read the story »
Nation’s cancer centers endorse HPV vaccination
News
Dr. Stillman and Dr. Tuveson joined with the leaders of other institutions nationwide in endorsing a statement regarding the HPV vaccine Read the story »
Alexander Dobin dives into genomic data
News
Alexander Dobin joins the faculty as its newest assistant professor, working on the computational side of genomics research Read the story »
Suffrage Science award to Mikala Egeblad
News
Egeblad and 10 other female scientists from around the world were presented with heirloom jewelry at the Suffrage Science awards ceremony. Read the story »
A better way to trace neuronal pathways
News
Researchers have improved a key method used to map circuits in the brain Read the story »
Microbial masterpieces win ASM Agar Art Contest
News
Science-inspired artworks created at CSHL’s DNA Learning Center win in the 2018 American Society for Microbiology Agar Art Contest Read the story »
Organoids predict treatment response for pancreatic cancer
3D balls of cancer cells quickly and accurately predict how patients with pancreatic cancer respond to a variety of treatments. Watch the video »
Organoid profiling personalizes treatments for pancreatic cancer
News
Pancreatic organoids grown from patients' tumors make precision medicine possible Read the story »
A science writer’s quest to understand heredity
Blog
LabDish spoke with science writer Carl Zimmer about what he learned about heredity as he zig-zagged through CSHL while writing his new book. Read the story »
Prof. Zachary Lippman named Blavatnik Award finalist
News
Professor Zachary Lippman was chosen as a Finalist in Life Sciences for the 2018 Blavatnik National Awards Read the story »
Scientists show how brain circuit generates anxiety
News
Researchers have identified a circuit in the brain that drives anxiety Read the story »
CSHL’s Zachary Lippman named HHMI Investigator
News
CSHL Professor Zach Lippman is selected as an HHMI investigator, in recognition of his innovative work in the field of plant genetics Read the story »
Pershing Square Sohn prize to Camila dos Santos
News
Assistant Professor Camila dos Santos, Ph.D., has been awarded the Pershing Square Sohn Prize for Young Investigators in Cancer Research. Read the story »
How do plants know when to flower?
Blog
Colorful flowers are a sure sign of spring. But how do flowering plants know that it is time to bloom? Read the story »
How pancreatic cancer spreads after surgery
News
Researchers have solved a mystery about how pancreatic cancer spreads Read the story »
How deadly cancer spreads after surgery
Scientists have solved an important mystery about how pancreatic cancer spreads to the liver even after a successful surgery. Watch the video »
A promising new strategy to combat familial dysautonomia
Scientists determine how to correct the error in RNA splicing that causes familial dysautonomia, a rare inherited neurodegenerative disorder. Watch the video »
The immune system, unleashed
Feature
Cancer immunotherapy has a long and storied history, one that begins with a young woman suffering from a pain in her hand Read the story »
Base Pairs Episode 15: The immune system unleashed
Cancer immunotherapy has a long and storied history, one that begins with a young woman suffering from a pain in her hand Listen to the podcast »
High schoolers reveal fraudulent herbal medicines
News
Some herbal products are not what they claim to be. These high school students and their mentor used DNA to investigate Read the story »
Nature’s masterpiece: the brain
Feature
A message from President and CEO Dr. Bruce Stillman from the Spring 2018 Harbor Transcript on the innovative research happening at CSHL Read the story »
How key brain receptor works in hostile conditions
News
A structural variation enables a key brain receptor to function in a hostile environment Read the story »
Bringing immune cells back into the cancer fight
Feature
Doug Fearon used a mouse model to discover how pancreatic cancer hides from the immune system. Read the story »
Cold Spring Harbor Laboratory celebrates its 15th commencement
News
Five students from the Watson School of Biological Sciences graduate, with special keynote speeches from Drs. David and Leon Botstein Read the story »
Therapeutic RNA corrects splicing defect that causes familial dysautonomia
News
A team provides proof of concept for an RNA drug correcting an error in RNA splicing that causes familial dysautonomia (FD) Read the story »
Portrait of a Neuroscience Powerhouse
Feature
A relatively small neuroscience group at CSHL is having an outsized impact on a dynamic and highly competitive field Read the story »
Watson School 2018 Ph.D.s
News
CSHL celebrates its 15th commencement, with five promising Ph.D. students graduating and honorary degrees presented to David and Leon Botstein Read the story »
Base Pairs Episode 14.5: Medicine and mad scientists
A follow-up discussion with CSHL Fellow Jason Sheltzer from Base Pairs episode 14, “The cancer answer that wasn’t.” Listen to the podcast »
David Tuveson elected to the AACR Board of Directors
News
CSHL Professor David Tuveson was elected to the Board of Directors of the American Association for Cancer Research for the 2018 - 2021 term Read the story »
Newly identified genetic mutation results in disability
Scientists have identified a new illness caused by a genetic mutation that gives rise to a wide range of symptoms including intellectual disability. Watch the video »
Newly identified genetic mutation results in intellectual disability and developmental delay
News
Scientists have identified a new illness caused by a genetic mutation that gives rise to a wide range of symptoms including intellectual disability Read the story »
CSHL’s Base Pairs is a finalist for the 2018 Webby Awards
News
CSHL's podcast Base Pairs was nominated for a prestigious Webby award for best Science and Education podcast Read the story »
Andrew Whiteley appointed VP of Business Development and Technology Transfer at CSHL
News
Life science business leader Andrew Whiteley becomes the Vice President of CSHL's Business Development and Technology Transfer department. Read the story »
Study reveals a way to make prostate cancer cells run out of energy and die
News
In lethal prostate cancer, the gene PTEN is often missing. In such cases, one effective treatment may be to administer drugs that inhibit mitochondria Read the story »
Research profile: Robert Maki
Feature
Straddling CSHL and Northwell Health gives Dr. Maki the perspective he needs to bring cancer research closer to the practice of treating patients Read the story »
The course to science stardom
Feature
At least 10 CSHL Courses alumni have gone on to win a Nobel Prize, while others have become leaders of major scientific institutions Read the story »
Revolutionary brain mapping: hundreds of neurons tracked in a week
Researchers used MAPseq, a revolutionary brain mapping method, to make a discovery that will force neuroscientists to rethink how areas of the cortex. Watch the video »
Revolutionary brain-mapping technique provides new blueprint for cortical connections
News
Researchers used MAPseq, a revolutionary brain mapping method, to make a discovery that will force neuroscientists to rethink how areas of the cortex Read the story »
Evans Foundation MDS Young Investigator Award to Lingbo Zhang
News
CSHL Fellow Lingbo Zhang received a Young Investigator Award from the Edward P. Evans Foundation. Read the story »
CRISPR-based system highlights new drug targets in a deadly leukemia
CRISPR was used to find 2 new druggable targets in a deadly leukemia. Watch the video »
One experiment: Twice the tomatoes
Feature
Zachary Lippman’s team found a way to boost tomato yield by digging into the plant’s genome and fine-tuning its branching patterns. Read the story »
Unique communication strategy discovered in pathway controlling plant growth
News
Scientists have identified a receptor on plant stem cells that can issue different instructions about how the plant will grow. Read the story »
The cancer answer that wasn’t
Feature
We look at the "reproducibility crisis" in science, with a cancer researcher discovering something he didn't expect while experimenting with MELK Read the story »
Base Pairs Episode 14: The cancer answer that wasn’t
We look at the "reproducibility crisis" in science, with a cancer researcher discovering something he didn't expect while experimenting with MELK Listen to the podcast »
Ratner and Weisbrod join Cold Spring Harbor Laboratory Board of Trustees
News
Bruce Ratner and Stuart Weisbrod were elected to the Cold Spring Harbor Laboratory Board of Trustees Read the story »
CRISPR-based system identifies important new drug targets in a deadly leukemia
News
CRISPR was used to find 2 new druggable targets in a deadly leukemia Read the story »
Kids today are doing what forensics experts couldn’t just 25 years ago
Blog
An 11-year-old student uses DNA testing to try to solve a 5,000-year-old murder mystery at CSHL’s DNA Learning Center. Read the story »
New method identifies splicing biomarkers for liver cancer
News
Researchers have developed a method for identifying splicing-based biomarkers for liver cancer Read the story »
New CSHL Fellow studies nexus of diet, metabolism, and cancer
News
CSHL Fellow Semir Beyaz works on the effects of what we eat and how it affect the incidence of colorectal cancers. Read the story »
One experiment: When cancer is hiding in plain sight
Feature
Douglas Fearon's team is figuring out how to get immune cells to recognize—and kill—pancreatic cancer cells Read the story »
The secret to tripling the number of grains in sorghum and perhaps other staple crops
News
A simple genetic modification can triple grain production in sorghum, a drought-tolerant plant that is an important source of food and animal feed. Read the story »
Science self-corrects: cancer gene does not pass reproducibility test
News
CSHL Fellow Jason Sheltzer and his research team use CRISPR to discover that MELK is not actually involved in cancer. Read the story »
Autism genetics study calls attention to impaired motor skills, general cognitive impairment
News
New research on the genetic causes of autism calls attention to diminished motor skills and suggests the importance of broad cognitive impairment Read the story »
PLOS and CSHL enter agreement to enable preprint posting on bioRxiv
News
The Public Library of Science (PLOS) will now be automatically posting papers submitted to its journal on bioRxiv, CSHL's preprint server Read the story »
Welcome to the real world of science, I’ll be your guide
Blog
Jackie Novatt was determined to show the people on her campus tours how science really works—and landed her dream job in the process. Read the story »
Dr. Leemor Joshua-Tor honored with Mildred Cohn Award from ASBMB
News
Professor Leemor Joshua-Tor receives the American Society for Biochemistry and Molecular Biology’s 2018 Mildred Cohn Award in Biological Chemistry. Read the story »
More rice, please: 13 rice genomes reveal ways to keep up with ever-growing population
News
Rice provides 20% of calories consumed. As the population grows toward 9 billion and the climate shifts, we'll need to grow more rice in more places. Read the story »
At CSHL, Congressman Suozzi celebrates scientific achievements of local HS students
News
Congressman Suozzi hosts congratulatory event at CSHL for high school science competition winners, including two Partners for the Future participants. Read the story »
Evolving sets of gene regulators explain some of our differences from other primates
News
What makes us different from our primate relatives? Gene regulation is one important evolutionary factor Read the story »
New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes
News
CSHL scientists have designed software that enables biologists to determine with unprecedented accuracy how much protein a given cell is making. Read the story »
45 years later, a scientist realizes he’s a star
Blog
David Haas was stunned to learn the impact of work he abandoned decades ago. He took a CSHL course to see it for himself. Read the story »
Visualizing how new DNA is born
CSHL President Bruce Stillman researches how cells are unfathomably busy making millions of copies of your DNA. Watch the video »
Christina Renna Foundation raises $30,000 for continuing pediatric cancer research at CSHL
News
The Christina Renna Foundation donates over $30,000 for rhabdomyosarcoma research, and honors Associate Professor Chris Vakoc with its research award Read the story »
CSHL’s Rob Martienssen honored with prestigious Barbara McClintock Prize
News
Plant geneticist Rob Martienssen awarded prestigious McClintock Prize. Read the story »
Counting chromosomes: Plant scientists solve a century-old mystery about reproduction
News
Geneticists have solved a century-old mystery by discovering a remarkable mechanism that enables plants to count their chromosomes Read the story »
Turning off the immune system is hard. Turning it on against cancer is easier.
Blog
How Professor Doug Fearon’s experiences with autoimmune disease patients contributed to the discovery of a new potential immunotherapy for cancer. Read the story »
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