Dr. Zador wins Transformative Investigator award
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Institutional
CSHL professor Anthony Zador wins Gill Symposium prize for his innovative work on MAPseq....
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Seeding citizen science with DNA barcoding
News
Education
Teachers trained in DNA barcoding can mentor students as they become citizen scientists investigating what interests them most...
Elisabeth R. Woods Foundation donates to cancer research
News
Giving
The Elisabeth R. Woods Foundation donated $30,000 for lung cancer research at their donor gathering, hosted at CSHL...
Big plans for a tiny plant
Feature
Research
On this episode of Base Pairs, Rob Martienssen discusses how duckweed could be the next biofuel and help combat climate change...
Massive genome havoc in breast cancer is revealed
News
Research
Researchers have made a highly detailed map of 20,000 structural variations in a cancer cell’s genome...
CSHL Fellow Semir Beyaz wins three awards
News
Institutional
Semir Beyaz has won three awards for his research on the impact of dietary choices on the body’s immunity against cancer...
International camp counselors tour CSHL
News
Giving
Counselors from the North Shore Holiday House camp toured CSHL to learn about its innovative research...
Nicholas Tonks wins prestigious ASBMB award
News
Institutional
Professor Nicholas Tonks wins Earl and Thressa Stadtman Distinguished Scientist Award from the American Society for Biochemistry and Molecular Biology...
CSHL spinoff wins investment prize
News
Research
CSHL spinoff company MapNeuro Inc., which uses tech developed in Zador lab, wins 2018 Seed Capital Prize from Alexandria LaunchLabs...
Progress toward improved Wilson’s disease drug
News
Research
Encouraging early results in a potential new treatment for Wilson's disease...
CSHL receives its 17th 4-star rating from Charity Navigator
News
Giving
Cold Spring Harbor Laboratory has received Charity Navigator’s highest possible 4-star rating for the 17th time...
Researchers discover new type of lung cancer
News
Research
Researchers have discovered a new form of lung cancer....
Postdoc wins Indian National Science Academy prize
News
Institutional
Dhananjay Huilgol, a postdoc in Professor Joshua Huang’s lab, wins one of India’s highest honors for young investigators...
Hotchkiss hosts 3rd ‘Paint the Path’ autism fundraiser
News
Giving
Students from The Hotchkiss School participated in their third annual “Paint the Path to Autism Research” event and raised $2,500 for autism research...
Being a scientist means being part of a team
Blog
Education
High school senior Jerinna Solages learns what it’s really like to do scientific research in CSHL’s Partners for the Future program...
The case for open and inclusive science
Feature
Institutional
America must continue to a place where the most talented people in the world want to live, study and work...
Nation’s cancer centers endorse HPV vaccination
News
Research
Dr. Stillman and Dr. Tuveson joined with the leaders of other institutions nationwide in endorsing a statement regarding the HPV vaccine...
Alexander Dobin dives into genomic data
News
Research
Alexander Dobin joins the faculty as its newest assistant professor, working on the computational side of genomics research...
Suffrage Science award to Mikala Egeblad
News
Institutional
Egeblad and 10 other female scientists from around the world were presented with heirloom jewelry at the Suffrage Science awards ceremony...
A better way to trace neuronal pathways
News
Research
Researchers have improved a key method used to map circuits in the brain...
Microbial masterpieces win ASM Agar Art Contest
News
Education
Science-inspired artworks created at CSHL’s DNA Learning Center win in the 2018 American Society for Microbiology Agar Art Contest...
Organoid profiling personalizes treatments for pancreatic cancer
News
Research
Pancreatic organoids grown from patients' tumors make precision medicine possible...
A science writer’s quest to understand heredity
Blog
Research
LabDish spoke with science writer Carl Zimmer about what he learned about heredity as he zig-zagged through CSHL while writing his new book...
Prof. Zachary Lippman named Blavatnik Award finalist
News
Institutional
Professor Zachary Lippman was chosen as a Finalist in Life Sciences for the 2018 Blavatnik National Awards...
Scientists show how brain circuit generates anxiety
News
Research
Researchers have identified a circuit in the brain that drives anxiety...
CSHL’s Zachary Lippman named HHMI Investigator
News
Institutional
CSHL Professor Zach Lippman is selected as an HHMI investigator, in recognition of his innovative work in the field of plant genetics...
Pershing Square Sohn prize to Camila dos Santos
News
Institutional
Assistant Professor Camila dos Santos, Ph.D., has been awarded the Pershing Square Sohn Prize for Young Investigators in Cancer Research....
How do plants know when to flower?
Blog
Research
Colorful flowers are a sure sign of spring. But how do flowering plants know that it is time to bloom?...
How pancreatic cancer spreads after surgery
News
Research
Researchers have solved a mystery about how pancreatic cancer spreads...
The immune system, unleashed
Feature
Research
Cancer immunotherapy has a long and storied history, one that begins with a young woman suffering from a pain in her hand...
High schoolers reveal fraudulent herbal medicines
News
Education
Some herbal products are not what they claim to be. These high school students and their mentor used DNA to investigate...
Nature’s masterpiece: the brain
Feature
Institutional
A message from President and CEO Dr. Bruce Stillman from the Spring 2018 Harbor Transcript on the innovative research happening at CSHL...
How key brain receptor works in hostile conditions
News
Research
A structural variation enables a key brain receptor to function in a hostile environment...
Bringing immune cells back into the cancer fight
Feature
Research
Doug Fearon used a mouse model to discover how pancreatic cancer hides from the immune system...
Cold Spring Harbor Laboratory celebrates its 15th commencement
News
Education WSBS
Five students from the Watson School of Biological Sciences graduate, with special keynote speeches from Drs. David and Leon Botstein...
Therapeutic RNA corrects splicing defect that causes familial dysautonomia
News
Research
A team provides proof of concept for an RNA drug correcting an error in RNA splicing that causes familial dysautonomia (FD)...
Portrait of a Neuroscience Powerhouse
Feature
Research
A relatively small neuroscience group at CSHL is having an outsized impact on a dynamic and highly competitive field...
Watson School 2018 Ph.D.s
News
Education WSBS
CSHL celebrates its 15th commencement, with five promising Ph.D. students graduating and honorary degrees presented to David and Leon Botstein...
David Tuveson elected to the AACR Board of Directors
News
Institutional Research
CSHL Professor David Tuveson was elected to the Board of Directors of the American Association for Cancer Research for the 2018 - 2021 term...
Newly identified genetic mutation results in intellectual disability and developmental delay
News
Research
Scientists have identified a new illness caused by a genetic mutation that gives rise to a wide range of symptoms including intellectual disability...
Nobelist Jim Watson is honored on his 90th birthday
News
Giving
Dr. James D. Watson celebrated his 90th birthday on April 6 with a gala piano concert and dinner, which helped raise money for an endowment...
CSHL’s Base Pairs is a finalist for the 2018 Webby Awards
News
Institutional
CSHL's podcast Base Pairs was nominated for a prestigious Webby award for best Science and Education podcast...
Andrew Whiteley appointed VP of Business Development and Technology Transfer at CSHL
News
Institutional
Life science business leader Andrew Whiteley becomes the Vice President of CSHL's Business Development and Technology Transfer department....
Study reveals a way to make prostate cancer cells run out of energy and die
News
Research
In lethal prostate cancer, the gene PTEN is often missing. In such cases, one effective treatment may be to administer drugs that inhibit mitochondria...
Research profile: Robert Maki
Feature
Research
Straddling CSHL and Northwell Health gives Dr. Maki the perspective he needs to bring cancer research closer to the practice of treating patients...
The course to science stardom
Feature
Education
At least 10 CSHL Courses alumni have gone on to win a Nobel Prize, while others have become leaders of major scientific institutions...
Revolutionary brain-mapping technique provides new blueprint for cortical connections
News
Research
Researchers used MAPseq, a revolutionary brain mapping method, to make a discovery that will force neuroscientists to rethink how areas of the cortex ...
Evans Foundation MDS Young Investigator Award to Lingbo Zhang
News
Research
CSHL Fellow Lingbo Zhang received a Young Investigator Award from the Edward P. Evans Foundation...
One experiment: Twice the tomatoes
Feature
Research
Zachary Lippman’s team found a way to boost tomato yield by digging into the plant’s genome and fine-tuning its branching patterns....
Unique communication strategy discovered in pathway controlling plant growth
News
Research
Scientists have identified a receptor on plant stem cells that can issue different instructions about how the plant will grow....
How the mouse got its stripes
News
Education WSBS
Dr. Hopi Hoekstra, Prof. of Zoology, Harvard University, spoke at the 21st Gavin G. Borden lecture about how the African striped mouse got is stripes...
The cancer answer that wasn’t
Feature
Research
We look at the "reproducibility crisis" in science, with a cancer researcher discovering something he didn't expect while experimenting with MELK...
Ratner and Weisbrod join Cold Spring Harbor Laboratory Board of Trustees
News
Institutional
Bruce Ratner and Stuart Weisbrod were elected to the Cold Spring Harbor Laboratory Board of Trustees...
CRISPR-based system identifies important new drug targets in a deadly leukemia
News
Research
CRISPR was used to find 2 new druggable targets in a deadly leukemia...
Kids today are doing what forensics experts couldn’t just 25 years ago
Blog
Education
An 11-year-old student uses DNA testing to try to solve a 5,000-year-old murder mystery at CSHL’s DNA Learning Center...
New method identifies splicing biomarkers for liver cancer
News
Research
Researchers have developed a method for identifying splicing-based biomarkers for liver cancer...
New CSHL Fellow studies nexus of diet, metabolism, and cancer
News
Research
CSHL Fellow Semir Beyaz works on the effects of what we eat and how it affect the incidence of colorectal cancers....
One experiment: When cancer is hiding in plain sight
Feature
Research
Douglas Fearon's team is figuring out how to get immune cells to recognize—and kill—pancreatic cancer cells...
The secret to tripling the number of grains in sorghum and perhaps other staple crops
News
Research
A simple genetic modification can triple grain production in sorghum, a drought-tolerant plant that is an important source of food and animal feed....
Science self-corrects: cancer gene does not pass reproducibility test
News
Research
CSHL Fellow Jason Sheltzer and his research team use CRISPR to discover that MELK is not actually involved in cancer....
Autism genetics study calls attention to impaired motor skills, general cognitive impairment
News
Research
New research on the genetic causes of autism calls attention to diminished motor skills and suggests the importance of broad cognitive impairment...
PLOS and CSHL enter agreement to enable preprint posting on bioRxiv
News
Institutional
The Public Library of Science (PLOS) will now be automatically posting papers submitted to its journal on bioRxiv, CSHL's preprint server...
Welcome to the real world of science, I’ll be your guide
Blog
Institutional
Jackie Novatt was determined to show the people on her campus tours how science really works—and landed her dream job in the process....
Dr. Leemor Joshua-Tor honored with Mildred Cohn Award from ASBMB
News
Institutional
Professor Leemor Joshua-Tor receives the American Society for Biochemistry and Molecular Biology’s 2018 Mildred Cohn Award in Biological Chemistry....
More rice, please: 13 rice genomes reveal ways to keep up with ever-growing population
News
Research
Rice provides 20% of calories consumed. As the population grows toward 9 billion and the climate shifts, we'll need to grow more rice in more places....
At CSHL, Congressman Suozzi celebrates scientific achievements of local HS students
News
Education
Congressman Suozzi hosts congratulatory event at CSHL for high school science competition winners, including two Partners for the Future participants...
Evolving sets of gene regulators explain some of our differences from other primates
News
Research
What makes us different from our primate relatives? Gene regulation is one important evolutionary factor...
New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes
News
Research
CSHL scientists have designed software that enables biologists to determine with unprecedented accuracy how much protein a given cell is making...
45 years later, a scientist realizes he’s a star
Blog
Education
David Haas was stunned to learn the impact of work he abandoned decades ago. He took a CSHL course to see it for himself....
Christina Renna Foundation raises $30,000 for continuing pediatric cancer research at CSHL
News
Giving Institutional
The Christina Renna Foundation donates over $30,000 for rhabdomyosarcoma research, and honors Associate Professor Chris Vakoc with its research award...
CSHL’s Rob Martienssen honored with prestigious Barbara McClintock Prize
News
Institutional
Plant geneticist Rob Martienssen awarded prestigious McClintock Prize...
Counting chromosomes: Plant scientists solve a century-old mystery about reproduction
News
Research
Geneticists have solved a century-old mystery by discovering a remarkable mechanism that enables plants to count their chromosomes...
Turning off the immune system is hard. Turning it on against cancer is easier.
Blog
Research
How Professor Doug Fearon’s experiences with autoimmune disease patients contributed to the discovery of a new potential immunotherapy for cancer...
YouTube videos earned her school a new lab from CSHL. Here’s how.
News
Education
Student wins back-to-back prizes from Silicon Valley. One such prize, a lab designed by CSHL’s DNA Learning Center, was awarded to her high school....
Three Strohm Sisters Family Foundation donates $5,000 for research on lung cancer recurrence
News
Giving
On December 18, a representative of the Three Strohm Sisters Family Foundation gave $5,000 for lung cancer recurrence research in Mikala Egeblad's lab...
Molecular decoy helps researchers halt and reverse acute leukemia in mice
News
Research
By throwing a molecular wrench into the gears of a machine that sets genes into motion, researchers were able to get leukemias to 'melt away.'...
A Cure Within documents the human stories behind cancer immunotherapy
News
Institutional
Immunotherapy as a cancer treatment may be cutting-edge, but it has a history. It’s the result of years of work by many dedicated researchers, some...
CSHL’s Bo Li receives BRAIN Initiative funding
News
Research
CSHL Professor Bo Li and two collaborators at Oregon Health & Science University (OHSU) have been awarded a new grant under the BRAIN Initiative...
Seahawks help CSHL tackle autism
News
Giving
CSH Seahawks Varsity football team present Professor Michael Ronemus with a check for $5,000 toward autism research...
A lesson in class
Feature
Research
In this episode of Base Pairs, we discuss how genetic information is changing how we define important categories....
David Spector is named ASCB Fellow
News
Institutional
David L. Spector was named a fellow of The American Society for Cell Biology...
Dr. Anne Churchland honored with Marshall Award for promoting women in science
News
Institutional
Associate Professor Anne Churchland was honored with The Louise Hanson Marshall Special Recognition Award...
Next Generation Lyme disease tests found efficacious and ready for clinical arena
News
Banbury Research
Experts find that current protocols for Lyme disease lacks the accuracy and sensitivity that next-generation testing can provide....
A spot at the podium: The Women in Biology Speakers List
Blog
Education
The gender imbalance in slates of invited speakers for scientific conferences is an issue that CSHL's Women in Science and Engineering (WiSE) group...
New method to determine before surgery which prostate tumors pose a lethal threat
News
Research
The news about prostate cancer can be confusing. It’s the third most common cancer type among Americans...
Research profile: Leemor Joshua-Tor
Feature
Research
A CSHL faculty member since 1995, a professor since 2005, Joshua-Tor is among the most distinguished members of the Laboratory community....
Next-gen cancer test
Feature
Research
Knowing that cancers become lethal when they spread, investigators at Cold Spring Harbor Laboratory seek a way of detecting tumors much earlier ...
One experiment: A beautiful brain, neuron by neuron
Feature
Research
Associate Professor Pavel Osten and colleagues discovered using their qBrain method is discerned by probing hidden relations among the dots....
A transformative partnership
News
Institutional
New York Governor Andrew M. Cuomo visited Cold Spring Harbor Laboratory to break ground on the new $75 million Center for Therapeutics Research....
“Hi, my name is Brian”…“and I’m Andrea”
News
Research
We’re the hosts of Base Pairs, a podcast from Cold Spring Harbor Laboratory that tells stories about the power of genetic information—past, present an...
Hungry for science
News
Giving Institutional
The 12th annual Women’s Partnership for Science luncheon celebrated honorary director of the CSHL Association Freddie Staller....
Double Helix Medals dinner
Feature
Institutional
The 2017 Double Helix Medals were presented to Tom Brokaw and Helen Ann and Charles Dolan....
Welcome back, Dr. Myat
News
Education WSBS
Monn Monn Myat, Ph.D., is the new Associate Dean of the Watson School of Biological Sciences....
Additional brain power
News
Research
For neuroscientists, the brain presents an almost endless number of mysteries to be solved....
Toasting serendipity
News
Research
Four decades ago, scientists made a discovery that “completely transformed all of biology,” according to Nobelist James Watson. ...
Light, cryptochromes, action…
News
Research
Assistant Professor Ullas Pedmale has received the National Institutes of Health "Outstanding Investigator Award."...
Hannon named director of Cancer Research UK Cambridge Institute
News
Education WSBS
Dr. Greg Hannon has been named the new director of the Cancer Research UK Cambridge Institute, effective February 1, 2018....
12th Double Helix Medals dinner raises $4.5 million for research & education at Cold Spring Harbor Laboratory
News
Giving Institutional
More than $4.5 million was raised last night at Cold Spring Harbor Laboratory’s (CSHL) 12th Double Helix Medals dinner (DHMD)....
Big decisions
Feature
Research
David Micklos of the DNA Learning Center, and Miriam Rich, a research scholar, talk about the big issues of eugenics....
Friends of T.J. present $50,000 gift for ongoing rhabdomyosarcoma research
News
Giving Institutional WSBS
The Friends of T.J. Foundation presented CSHL Associate Professor Chris Vakoc with a check for $50,000 for his ongoing rhabdomysarcoma research...
Fantastic journey: how newborn neurons find their proper place in the brain
News
Research
Neuroscientists have clarified the mechanism used by newly born neurons in mice to migrate to very specific areas....
For brain cells, you are who you speak to
Blog
Research
Tracking a person entails searching through their email, phone, and other means of communication to map out their network. To do this for a brain cell...
New leadership roles in BRAIN Initiative and International Brain Lab reflect CSHL’s excellence in neuroscience
News
Research
The BRAIN Initiative Cell Census Network establishes a Center and a Collaboratory for the Mouse Brain Cell Atlas at Cold Spring Harbor Laboratory ...
Cryo-EM imaging suggests how the double helix separates during replication
News
Research
Special cryo-EM imaging helps figure out how the double helix of DNA separates when it replicates...
Research revises our knowledge of how the brain learns to fear
News
Research
A team at Cold Spring Harbor Laboratory led by Professor Bo Li found evidence indicating the central amygdala is key to to aversive learning....
One experiment: Bacteria-trapping DNA webs are repurposed by cancer cells
Feature
Research
Associate Professor Mikala Egeblad discovers that neutrophil extracellular traps (NETs) help cancer by creating holes in the tissue....
Masthead Cove Yacht Club raises over $6000 for CSHL research at annual race
News
Giving
Members of the Masthead Cove Yacht Club (MCYC) raised $6,700 from their annual Masthead Race on August 13....
Good genes, bad science
Feature
Research
On this episode, Base Pairs looks into the eugenics movement, including the record kept in CSHL....
Governor Cuomo breaks ground on $75 million Cold Spring Harbor Laboratory Center for Therapeutics Research
News
Institutional
NY Governor Andrew M. Cuomo visited Cold Spring Harbor Laboratory (CSHL) this morning to break ground on the new $75 million Center for Therapeutics....
First cell-type census of mouse brains: surprises about structure, male-female differences
News
Research
A multiyear project in the Brain Initiative, qBrain is already revealing the brain as never before....
Do neuroscientists need to switch gears to understand how brains make choices?
Feature
Research
Associate Professor Anne Churchland, co-founder the IBL along with Professor Tony Zador, explains how it could help solve a problem in neuroscience....
16th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory
News
Giving Institutional
Cold Spring Harbor Laboratory held the 16th annual Women's Partnership for Science luncheon, a summer staple among New York's female philanthropists....
Neuron types in the brain are defined by gene activity that shapes their communication patterns
News
Research
Neurons are defined by determining which cells they connect with and how they communicate across synapses ...
What Silicon Valley and biology research share
Feature
Research
Further discussion with Associate Professor Gurinder "Mickey" Atwal about the need for more math and physics in biology....
Plant geneticists develop a new application of CRISPR to break yield barriers in crops
News
Research
Mutating regulatory regions varies yield traits the way a dimmer switch controls a light bulb...
Halfway around the world, a reunion of friends opens door to a cancer discovery
Blog
Research
After interviewing for a position in a pancreatic cancer lab at Cold Spring Harbor Laboratory, 7,000 miles from his hometown in South Korea, Chang-il...
Research reveals “exquisite selectivity” of neuronal wiring in the cerebral cortex
News
Research
Inhibitory chandelier cells receive and transmit information from different ensembles of excitatory cells in their cortical neighborhood ...
2nd Annual WiSE Summer Party provides needed networking opportunity
News
Institutional
CSHL Women in Science and Engineering and the Postdoctoral Liaison Committee co-hosted the 2nd annual Greater NYC WiSE Summer Beach Party...
Realizing a dream: How a program for undergraduates placed me at the center of CRISPR research
Blog
Education
Hands-on experience using CRISPR and access to top scientists from around the world who are pioneering its use made this a memorable summer for...
Biology, behind the screens
Feature
Research
Associate Professor Gurinder "Mickey" Atwal talks about the essential mystery at the center of quantitative biology....
Structural view suggests RNAi machinery multiplies its efficiency in repressing gene expression
News
Research
Leemor Joshua-Tor publishes atomic-resolution pictures and an analysis of RNAi machinery...
CSHL’s Kepecs receives BRAIN Initiative grant to develop tools to guide behavioral research
News
Institutional
Dr. Adam Kepecs receives grant to develop conceptual infrastructure for behavioral neuroscience research...
Long-sought mechanism of metastasis is discovered in pancreatic cancer
News
Research
An epigenetic factor reprograms gene enhancers, enabling cancer cells to “remember” an earlier developmental state and causing metastasis. ...
Team traces masculinization in mice to estrogen receptor in inhibitory neurons
News
Research
CSHL researchers discover when ERα receptors are deleted in the brains of male mice, they do not exhibit typical "masculine" behaviors during puberty....
Science and architecture: Back to the future!
Blog
History Institutional
3D images are a throwback to the past as CSHL and Centerbrook Architects rediscover a 1950s building that has been occupied by some of the Laboratory...
Library of CRISPR targeting sequences increases power and accuracy of the gene-editing method
News
Research
New library of RNA sequences that can be used by researchers to direct the CRISPR-cas9 complex to cut DNA with unprecedented precision....
Tomato baby and its family
Feature
Research
This episode of Base Pairs talks to Associate Professor Zachary Lippman about all the weird mutations that naturally occur in plants....
Eugenics used to be incredibly popular. We can’t let that happen again.
Blog
History Institutional
Miriam Rich, the recipient of CSHL’s 2017-18 Sydney Brenner Research Scholarship, is determined to show how the concept of “good genes” became...
Freeze-frames of enzymes in action have implications for a new cancer treatment concept
News
Research
TUTase enzymes interact with let-7, a regulator of development; targeting them could help control certain cancers....
Newly identified small RNA fragments defend the genome when it’s ‘naked’
News
Research
Fragments snipped from tRNAs protect embryonic stem cells while they’re being epigenetically reprogrammed....
Over $300,000 raised for research and education at 24th annual golf outing
News
Giving
Over 180 golfers took to the greens at Piping Rock Club at Cold Spring Harbor Laboratory’s 24th annual golf tournament....
Latest advances in malaria research in free eBook by Cold Spring Harbor Laboratory Press
News
Institutional
J.C. Flowers Foundation grant gives practitioners in malaria-endemic areas access to a critical resource...
New statistical method finds shared ancestral gene variants involved in autism’s cause
News
Research
Researchers find children with autism are genetically more like other autistic children than their unaffected siblings....
CRISPR vs. climate change
Feature
Research
This episode of Base Pairs looks at the issues climate change may bring to agriculture and how CRISPR can help overcome them....
How cool is science? Students use barcoded DNA to identify a weapon against antibiotic resistance
Blog
Education
Sometimes viruses cause harmful infections, but students in the DNA Learning Center’s Urban Barcode Research Program identified a new virus that could...
Open House brings 500+ new friends to Cold Spring Harbor Laboratory campus
News
Education Institutional
Cold Spring Harbor Laboratory (CSHL) welcomed 500+ new friends on June 10, 2017 to share the thrill of scientific discovery....
Detailed new ‘reference’ genome for maize shows the plant has deep resources for continued adaptation
News
Research
A new, much more detailed reference genome for maize, or corn, as it is called in the U.S., provides new insight into the crop....
Math teacher wins school popularity contest (again)
Blog
Education
Math isn’t exactly known as “everyone’s favorite subject,” yet Associate Professor Mickey Atwal has won the Watson School of Biological Science’s...
A protein that stem cells require could be a target in killing breast cancer cells
News
Research
Cancer cells, like stem cells, have the ability to multiply indefinitely but epigenetic factor BPTF may be a shared weakness....
Hanging with Heroes and Friends Who Care raise over $17,000 to support Cold Spring Harbor Laboratory’s Breast Cancer Research
News
Giving
On Saturday, April 22, 2017, 245 people attended the 4th annual Hanging with Heroes fundraiser held at Driftwood Camp in Melville. ...
Fine-tuning dosage of mutant genes unleashes long-trapped yield potential in tomato plants
News
Research
Understanding gene interactions can enable breeders to break existing productivity barriers in agriculture....
Is confidence measurable?
Blog
Research
Confidence is “not just a feeling,” according to neuroscientist Adam Kepecs. Finding the confidence-calculating circuitry in our brains has huge...
Redefining biologists, redefining genes
Feature
Research
Drs. Molly Hammell and Thomas Gingeras talk about redefining what a biologist is and what genes are....
CSHL to lead international team developing next-generation organoid cancer research
News
Research
Cold Spring Harbor Laboratory (CSHL) has been awarded a research subcontract by Leidos Biomedical Research to lead a Cancer Model Development Center (CMDC) for pancreatic, breast, colorectal, lung, liver and other upper-gastrointestinal cancers....
Nobel laureate Dr. Carol Greider gives keynote at Cold Spring Harbor Laboratory graduation
News
Education WSBS
Eight new Ph.D.s join 90 alumni who have earned a degree from the Watson School of Biological Sciences in the 18 years since its accreditation....
Newly discovered mutations impair key cell pathways in pancreatic cancer
News
Research
Researchers have found important new clues to the development of pancreatic cancer....
Pershing Square Sohn cancer research prize awarded to CSHL’s Dr. Mikala Egeblad
News
Research
Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad, Ph.D., has been awarded the Pershing Square Sohn Prize....
CSHL’s Dr. Leemor Joshua-Tor is elected to The National Academy of Sciences
News
Research
Professor Leemor Joshua-Tor has been elected to The National Academy of Sciences (NAS)....
Alexa DeAngelis didn’t see a place for herself in science, so she’s making one
Blog
Education
For Alexa DeAngelis, who was recently awarded a Fulbright scholarship, combining a desire to help people with a passion for biochemistry means design...
Cold Spring Harbor Laboratory to boost sharing of global scientific research in collaboration with the Chan Zuckerberg Initiative
News
Institutional Research
To accelerate the pace of scientific discovery, the bioRxiv preprint service will advance free distribution of research manuscript drafts....
Everyday steps you can take for science
Blog
Education
Effective advocacy for science is the culmination of many small steps...
Dark matter of the genome, part 2
Feature
Research
This episode of Base Pairs deals with the myth of "junk DNA" and why scientists are interested in non-coding portions of the genome....
CSHL’s Dr. Leemor Joshua-Tor Elected to American Academy of Arts and Sciences
News
Research
Professor Leemor Joshua-Tor is among 228 newly elected members of The American Academy of Arts and Sciences...
New research explains why even targeted therapies eventually fail in lung cancer
News
Research
Dr. Sordella and her team propose a novel theory of how some cancers circumvent the killing power of targeted therapies....
Research suggests a possible role for a storm of ‘jumping genes’ in ALS
News
Research
New research demonstrates that some transposons are no longer effectively inhibited, resulting in a storm of jumping genes, leading to DNA damage....
What a real-life science test looks like
Blog
Research
By revealing evidence that contradicts the rationale for a new cancer drug, a pair of student scientists learns firsthand that when you do science...
Trinity College President Joins Board of Cold Spring Harbor Laboratory
News
Institutional
Dr. Joanne Berger-Sweeney, president of Trinity College, was elected to the CSHL Board of Trustees....
Protein complex that takes first steps in human DNA replication dance is captured at high atomic resolution
News
Research
Human ORC complex captured in action in x-ray crystallography and cryo-EM...
Dark matter of the genome, part 1
Feature
Research
This episode of Base Pairs digs into "dark matter" a type of genetic information that could help scientists better understand diseases like...
Can we understand memories at the molecular level?
Blog
Research
Memories may seem intangible, but many scientists are working to figure out how they are physically stored in the brain. To achieve this, we’ll need ...
Dopamine neurons factor ambiguity into predictions that enable us to “win big and win often”
News
Research
Researchers describe how dopamine-releasing neurons weigh the ambiguity of sensory information, indicating that neurons are highly sophisticated....
New art supplies for visualizing tiny machines in the brain
Blog
Research
An unusual, but beautiful sight can be found among the figures of a recent scientific paper about some of the tiny machines in our brain: watercolor...
The Children’s Heart Foundation awards $50,000 to CSHL researcher
News
Giving Institutional
The New York Chapter of The Children’s Heart Foundation (CHF) presented Dr. Michael Ronemus of Cold Spring Harbor Laboratory (CSHL) a $50,000 grant....
Glen Cove CARES donates $7,000 to breast cancer research at CSHL
News
Giving
Marilyn Abrams and Lorri Prince of Glen Cove CARES presented a $7,000 check to Dr. Mikala Egeblad, Professor at Cold Spring Harbor Laboratory to support her breast cancer research...
Discovery of distinct cell subtypes around tumors helps explain why pancreatic cancer is so hard to treat
News
Research
Researchers finds that stroma,“wound”-like tissue that surrounds the tumors, helps explain why pancreatic cancer is so resistant to treatment....
Researchers identify “Achilles’ heel” of PTEN that helps drive prostate cancer progression
News
Research
Researchers at CSHL have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it....
CSHL statement regarding Executive Order on border security and immigration
News
Institutional
CSHL statement regarding Executive Order on border security and immigration...
Molecules and a mission
Feature
Research
A special bonus episode of Base Pairs offering an explanation of why the name "Base Pairs" was chosen...
In mouse model of Rett syndrome, research reveals how adult learning is impaired in females
News
Research
Researchers found that the failure of the Mecp2 gene, which leads to Rett syndrome, has biological consequences later in life....
Cancer research biobank formed by Northwell Health and Indivumed will enhance CSHL-Northwell alliance
News
Institutional
Northwell Health and Indivumed collaborate to greatly expand cancer biobanking activities within Northwell Health to develop medical approaches....
Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments
News
Research
Pre-malignant aneuploid cells grew more slowly and formed smaller tumors than comparable cells with normal chromosome number, CSHL researchers found....
CSHL joins NCI-designated cancer centers in endorsing updated HPV vaccination recommendations
News
Institutional
Dr. Stillman and Dr. Tuveson joined with the leaders of other institutions nationwide in endorsing a statement regarding the HPV vaccine....
Plus-sized fly: a model to understand the mechanisms underlying human obesity
News
Research
The fly sheds light on how the brain acts to signal “fullness” and the possibility of conferring resilience against the impact of high-fat diets...
Austin’s Purpose Raises $10,000 for Cold Spring Harbor Laboratory Neuroscience
News
Giving
Austin’s Purpose presented CSHL Hiro Furukawa with a donation to continue NMDA research....
Cold Spring Harbor Laboratory Sarcoma Research Update
News
Giving
Over the last two years, CSHL has applied its excellence in basic research and innovative technology development to understanding the rare but intractable sarcoma cancers. ...
FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL
News
Research
Nusinersen (Spinraza) will be used to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA)....
Join Glen Cove CARES for their 20th Anniversary
News
Giving Institutional
Join Glen Cove CARES for their 20th Anniversary celebration....
MWCABC donates $65,000 to breast cancer research at CSHL
News
Giving
The Manhasset Women's Coalition Against Breast Cancer presented a check to support Dr. Camila dos Santos' breast cancer research....
The brain atlas
Feature
Research
This episode of BasePairs looks at the problems of neuropsychiatric drug discovery, and the method by which they may soon be resolved....
Cold Spring Harbor HS Football Player donates CSHL’s breast cancer research
News
Giving
Eli Gordon, kicker for the Cold Spring Harbor football team, presented a check today for $1,000.00 for breast cancer research....
Dr. Robert Maki joins Northwell Health Cancer Institute and CSHL to direct Center for New Cancer Therapies
News
Research
Dr. Robert G. Maki an internationally-renowned sarcoma cancer physician and researcher, joins the leadership of the Northwell Health Cancer Institute....
For Alan Alda, science communication is a state of mind
Blog
Institutional
An interview with actor and science communication advocate Alan Alda about his work at the Alda Center for Communicating Science....
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
News
Research
Truncated p53 proteins, presumed unimportant, now point to new drug targets for some of "the hardest cancers"...
Annual Appeal letter
News
Giving
When you give to Cold Spring Harbor Laboratory, you are making an investment in the careers of young scientists....
Gene editing yields tomatoes that flower and ripen weeks earlier
News
Research
Researchers use CRISPR to expand the geographical range of important food crops....
11th Double Helix Medals raises $4.3 million for biomedical research and education at Cold Spring Harbor Laboratory
News
Giving Institutional
More than $4.3 million was raised last night at Cold Spring Harbor Laboratory’s 11th Double Helix Medals dinner, honoring Alan Alda and P. Roy Vagelos...
One experiment: A drug for SMA visibly repairs defective cells
Feature
Research
Professor Adrian Krainer develops a treatment for spinal muscular atrophy, the leading genetic cause of infant death....
Detailed images of NMDA receptor show how zinc and a potential drug affect its function
News
Research
Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia....
Dr. David Tuveson named Director, NCI-Designated Cancer Center at Cold Spring Harbor Laboratory
News
Institutional
Dr. David Tuveson, M.D., Ph.D., succeeds Dr. Bruce Stillman as Director of the Cold Spring Harbor Laboratory (CSHL) Cancer Center....
When antioxidants are pro-cancer
Feature
Research
For Pancreatic Cancer Awareness Month, Base Pairs looks at the science of antioxidants and cancer....
No (real) moustache required to join the “Movember” party
Blog
Research
Members of Trotman don fake moustaches in order to raise money for prostate cancer research during Movember. ...
Focus on quiescent cells brings to light the essential role of RNA interference in transcription control
News
Research
RNAi and other epigenetic processes induce changes in where and when specific genes are expressed without altering their genetic code....
Pancreas and colon tumors reprogram the liver, causing wasting and short-circuiting body’s immune response
News
Research
Research reveals a mechanism that causes wasting in cancer and tests a way to reverse it....
Gene network controls how many flowers and fruits plants will produce during critical growth window
News
Research
Researchers use RNA sequencing to identify a network of genes that work together to determine the duration of a critical window for growth....
The Claire Friedlander Family Foundation Donates $200,000 for New Sequencer
News
Giving
Claire Friedlander Family Foundation donated $200,000 for new equipment at the Woodbury Genome Center....
The “secret” science center where openness is everything
Blog
Banbury Research
Lyme disease researcher Steven Schutzer talks about the important meetings held in the Banbury Center....
A theoretical physicist’s approach to breast cancer
Blog
Research
Associate Professor Mickey Atwal explains how exploring numbers and patterns could lead to a new cancer treatment strategy....
Our most common infection-fighting white blood cells can be hijacked to support cancer spread
News
Research
Neutrophils, the most common type of white blood cell, can be taken over by cancer cells and used as an aid in metastasis....
Masthead Cove Yacht Club raises over $7000 for CSHL research at annual race
News
Giving Institutional
Members of the Masthead Cove Yacht Club (MCYC) raised $7,007 from their annual Masthead Race on August 14, 2016....
“Sink or swim”
Feature
Research
This episode of Base Pairs follows Professor Adrian Krainer and his experience as the first CSHL fellow....
What’s the connection between antioxidants and cancer?
Blog
Research
David Tuveson discusses the relationship between antioxidants and cancer, and how the former doesn't necessarily prevent the latter....
Non-coding portions of genome are found to play role in cancer
News
Research
CSHL scientists test an antisense method of targeting long noncoding RNAs overexpressed in breast cancers....
Three words I heard from my pediatric oncologist that still haunt me
Blog
Research
Kayla Funk, a childhood cancer survivor, on her experiences with pediatric cancer and the push for more funding for research....
Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly
News
Research
Researchers have uncovered a neural circuit that processes evaluations and have succeeded in identifying its sources....
Innovative tools will shed clarifying light on inhibitory neurons
News
Research
Researchers at Cold Spring Harbor Laboratory created a set of tools that combine genetic markers and virus particles to target GABA cell types....
15th Women’s Partnership for Science luncheon features Lasker Prize winner Evelyn Witkin
News
Institutional
15th Annual Women's Partnership raises over $200,000 for disease research at Cold Spring Harbor Laboratory...
LI2Day Walk supports Cold Spring Harbor Laboratory’s breast cancer research
News
Giving
LI2Day donated $2,000 to CSHL, having donated nearly $300,000 to support breast cancer research at the CSHL since 2004....
Stand Up for Suzanne donates $10,000 to Cold Spring Harbor Laboratory
News
Giving
Regina Caliendo and Doris Jelinek presented a $10,000 check to Dr. Sarah Diermeier for breast cancer research....
Why calling childhood cancers “rare” is missing the point
Blog
Research
Associate Professor Christopher Vakoc on why calling pediatric cancers "rare" actually hurts their chances of being studied....
The people problem
Feature
Research
This episode of Base Pairs looks at the rising population, plant biology, and the future of food....
How a cold-causing virus and inexplicable experiments helped revolutionize thinking about the genome
Blog
Research
Nobel laureate Richard Roberts discusses the importance of RNA splicing and how scientists can learn from "failed" experiments....
Preprint server bioRxiv receives additional major funding
News
Institutional
Increased support will fuel continued growth and technical development of the increasingly prominent biomedical preprint service....
Painting with microbes brings an unseen world into public view
Blog
Education
We live in exciting times. Until recently, the microscope was the only way for scientists to take a closer look at microorganisms. ...
Revolutionary method to map the brain at single-neuron resolution is successfully demonstrated
News
Research
MAPseq can trace the long-range projections of large numbers of individual neurons from a specific region to wherever they lead in the brain....
Non-modern family
Feature
Education Research
This episode on Base Pairs explores how genetic information to better understand human history....
Candidate drug for spinal muscular atrophy, with roots in CSHL research, passes major hurdle
News
Research
Biotechnology firms Biogen and Ionis Pharmaceuticals cut short a phase-3 clinical trial for the investigational drug nusinersen as it met endpoint....
Riding out of the shadows of ALS, toward better treatments
Blog
Research
Graduate student Lisa Krug discusses her research and personal connection to ALS, and Ride for Life, a not-for-profit organization for ALS research....
Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidants
News
Research
Researchers demonstrate that in the specific context of pancreatic cells leading to cancer, raisin antioxidant levels should not be raised....
To divide or not: a cellular feedback loop that enables new cells to make a fateful decision
News
Research
Team explains a key mechanism to prevent aberrant cell proliferation...
Science is hard, and these high schoolers are fine with that
Blog
Education
With DNA barcoding, high school seniors Sydney Lyncook and Tanjil Uddin realized that they had the power to show whether the manufacturers of ...
Corn controversy
Feature
Research
This episode of Base Pairs covers the contentious genetics and history of America’s corn production....
Discovery of new ovarian cancer signaling hub points to target for limiting metastasis
News
Research
A team of researchers at Cold Spring Harbor Laboratory discovers new insights into signaling events that underlie metastasis in ovarian cancer cells....
Academic-industry collaboration generates elegant way of pinpointing how a new drug exerts beneficial effects
News
Research
Researchers identify a new drug target in leukemia and creation of a candidate drug that hits the target....
One experiment: How the breast “remembers” a first pregnancy
Feature
Research
Professor Greg Hannon and his team, including Assistant Professor Camila dos Santos, learn more about breast cells and tissue....
Basic research needs your support
News
Research
CSHL partners with Research!America to find out where political candidates stand on support for basic research....
Cancer researcher Camila dos Santos of CSHL is named a Rita Allen Foundation Scholar
News
Institutional
Assistant Professor Camila dos Santos of Cold Spring Harbor Laboratory (CSHL) has been selected as one of seven 2016 Rita Allen Foundation Scholars. ...
“Amazing protein diversity” is discovered in the maize plant
News
Research
The genome of the corn plant “is a lot more exciting” than scientists have previously believed....
From phages to faces
Feature
Research
In the pilot episode of Base Pairs, two stories of DNA research that show how far the field has come...
Pew Trusts name CSHL’s Daniel Rodríguez-Leal a Latin American Fellow in Biomedical Sciences
News
Institutional
Daniel Rodríguez-Leal, Ph.D., a postdoctoral investigator was selected for the Pew Latin American Fellows in the Biomedical Sciences...
Don’t fall into the culture gap between science and business
Blog
Education
Key takeaways from the lecture “Bench to Bioscience Enterprise” which talks about the connections between business and science....
CSHL receives its 15th 4-star rating from Charity Navigator
News
Giving
Cold Spring Harbor Laboratory has received Charity Navigator’s highest possible 4-star rating for the 15th time...
The WTFC Foundation supports breast cancer research at CSHL
News
Giving
The WTFC Foundation held its 10th Annual "The Breast of Everything" fundraiser, raising over $40,000 to support breast cancer research...
DIY neuroscience opens up a universe of possibilities in Transylvania
Blog
Education
Do-it-yourself (“DIY”) science evokes images of amateur scientists tinkering with test tubes in garages on the weekends. So, at first, the picture of ...
Pershing Square Sohn Cancer Research Alliance awards prize to CSHL’s Christopher Vakoc
News
Institutional
Associate Professor Christopher Vakoc of Cold Spring Harbor Laboratory is among seven winners of the third annual Pershing Square Sohn Prize...
ALS Ride for Life comes to Cold Spring Harbor Laboratory
News
Giving Institutional
CSHL gathered to welcome Chris Pendergast and his ALS Ride for Life team to campus on Monday, May 16....
Discovery of new stem cell pathway indicates route to much higher yields in maize, staple crops
News
Research
Researchers discover a new regulatory pathway that channels signals emanating from a plant's extremities to the stem cell niche....
Our brain uses statistics to calculate confidence, make decisions
News
Research
The brain produces feelings of confidence that inform decisions the same way statistics pulls patterns out of noisy data....
Alumnus Josh Sanders makes neuroscience research tools open and affordable
News
Education WSBS
Josh Sanders developed a series of tools for neuroscience research that filled major needs in the field....
Cold Spring Harbor Laboratory confers 90th Ph.D.
News
Education WSBS
On May 1, proud friends and family mingled with distinguished scientists at the 13th commencement ceremony of the Watson School of Biological Sciences...
WSBS Teaching Award 2016 for Mickey Atwal
News
Education WSBS
Mickey Atwal is the third two-time winner of the Winship Herr Award for Excellence and Creativity in Teaching....
First structural views of the NMDA receptor in action will aid drug development
News
Research
Structural biologists obtained snapshots of the activation of an important type of brain-cell receptor....
Graduation 2016
News
WSBS
Watson School awards seven Ph.D. degrees, to students who studied topics ranging from single-cell sequence data analysis to acute myeloid leukemia....
Why is autism more common in boys?
Blog
Research
Ivan Iossifov talks about some of the reasons why autism disproportionately effects boys on a genetic level....
Cold Spring Harbor Laboratory launches $75 million Center for Therapeutics Research to develop new drugs
News
Institutional
CSHL announced the Center for Therapeutics Research project, applying biomedical expertise towards advancing therapeutics for genetic diseases....
What do autism “risk genes” do?
Blog
Research
A discussion with Ivan Iossifov with what exactly the term "risk genes" means and what they do....
Adrian Krainer of Cold Spring Harbor Laboratory elected to American Academy of Arts and Sciences
News
Institutional
Adrian Krainer was elected to the American Academy of Arts and Sciences....
Executive in Residence to mentor scientific entrepreneurs at Cold Spring Harbor Laboratory
News
Institutional
Andrew Whiteley joined the Cold Spring Harbor Laboratory Office of Technology Transfer as the first Executive in Residence....
How many autism “risk genes” have scientists found?
Blog
Research
A look at the research which points to the different genes potentially at the root of autism....
CSHL scientists Bo Li and Je Lee win HFSP Research Grant awards
News
Research
Associate Professor Bo Li and Assistant Professor Je Lee, are among 25 teams that have won Human Frontier Science Program Research Program Grants...
Where does autism come from when it doesn’t run in the family?
Blog
Research
Associate Professor Ivan Iossifov discusses how parents who are not autistic can pass autism onto their children through their genes....
U.S. Patent Office denies all 4 petitions filed by Benitec Biopharma against CSHL’s shRNA patents
News
Institutional
U.S. Patent & Trademark Office has denied all 4 petitions filed by Benitec Biopharma Ltd seeking to invalidate CSHL's patents directed to shRNA....
Imaging hundreds of neurons using ultrafast lasers hints at how brains make decisions
Blog
Research
Neuroscientist Matt Kaufman uses brief, ultrafast laser pulses to understand how the brain makes sensory-guided decisions....
If you thought all neuroscientists work with neurons, you’re wrong
Blog
Research
Neuroscientists talk about the importance of the intersections between theory and experiment, and how it has shaped their work....
Joni Gladowsky Foundation to hold breast cancer fundraiser for CSHL
News
Giving
The Joni Gladowsky Foundation holds its annual Winter Classic Hockey Tournament....
Student Lisa Krug quells the transposon storm of ALS
News
WSBS
Lisa Krug defended her Ph.D. thesis, in which she studied the molecular basis of ALS in a model organism: the fruit fly Drosophila melanogaster....
Neanderthals mated with modern humans much earlier than previously thought, study finds
News
Research
Using several different methods of DNA analysis, an international research team has found what they consider to be strong evidence of interbreeding....
Ancient gene network helps plants adapt to their environments
News
Research
Reseachers discovered the purpose of a tool present in both mosses and flowering plants, organisms whose common ancestor dates back 450 million years....
How healthy cells might help cancer survive
Blog
Research
A story on Mikala Egeblad's breast cancer research and the importance of the tumor microenvironment....
Stand Up for Suzanne’s annual luncheon will support breast cancer research at CSHL
News
Giving
Stand Up for Suzanne, a Long Island-based group founded to support cutting edge research at Cold Spring Harbor Laboratory held their annual luncheon...
A consortium to map the brain is launched
News
Research
The Wyss Institute for Biologically Inspired Engineering announced a cross-institutional consortium to map the brain's neural circuits....
Christina Renna Foundation Raises $35,000 for pediatric cancer research at CSHL
News
Giving Institutional
The Christina Renna Foundation presented $35,000 to Cold Spring Harbor Laboratory (CSHL) at its 9th annual Angel's Wish Gala....
CSHL joins nation’s cancer centers in endorsement of HPV vaccination for cancer prevention
News
Institutional
Cold Spring Harbor Laboratory joined 68 other top cancer centers in issuing a statement urging increased HPV vaccination for the prevention of cancer...
Partners Profile: High School Senior Tamanna Bhatia on becoming a scientist
Blog
Education
An interview with Partners for the Future participant Tamanna Bhatia and her work in Alea Mill's lab studying cancer cells....
The iPlant Collaborative is now called CyVerse
News
Institutional
The enhanced NSF project will now provide data management and computation across scientific disciplines...
bioRxiv preprints can now be submitted directly to leading research journals
News
Research
Cold Spring Harbor Laboratory announced that authors of manuscripts posted on its preprint server can now submit papers directly to leading journals....
A new way to fear: Lady lab rats raise important questions for behavioral research
Blog
Research
A discussion of female rats as research subjects and how their hormonal cycle comes into play....
Solving the problem with penicillin
Blog
History Institutional
In celebration of scientist Milislav Demerec, a look at how he discovered a strain of Penicillium that more effectively produced pencillin....
Clark Gillies Foundation gives $50,000 for sarcoma research at CSHL
News
Giving Institutional
The Clark Gillies Foundation presented $50,000 to Cold Spring Harbor Laboratory (CSHL) in support of the Sarcoma Research Project...
Unusual drug target and drug generate exciting preclinical results in mouse models of metastatic breast cancer
News
Research
Researchers publish preclinical data suggesting the promise of a novel drug directed against a novel target n malignant mammary tumors....
5th Graders spend a day as young scientists
Blog
Education
Students from the West Side Elementary School learn about the history and workings of Cold Spring Harbor Laboratory....
New method prevents cells from prematurely halting protein production in certain genetic illnesses
News
Research
Research team succeeds in paradoxically inhibiting a process cells have evolved to prevent imperfect proteins from being synthesized...
Saving our food supply with alumna Michelle Cilia
News
WSBS
Dr. Michelle Cilia has made it her mission to understand the bacteria and viruses that strike plants—and how to stop them...
DNA Justice—How the courtroom can learn from science
Blog
History
The case of Marvin Lamont Anderson, who was exonerated through the use of DNA evidence....
Discovery of a new X-linked intellectual disability syndrome is aided by web communication tools
News
Research
A geneticist uses social media and online tools to help confirm, document and describe in precise clinical detail a new genetic syndrome in young ...
First direct evidence for synaptic plasticity in fruit fly brain
News
Research
Researchers have for the first time observed direct evidence of synaptic plasticity in fruit flies while they learn....
CSHL neuroscientist Anthony Zador is named a “Top 100 Global Thinker” of 2015
News
Institutional
Anthony Zador was selected by the editors of the prestigious journal Foreign Policy as one of the Top 100 Leading Global Thinkers of 2015....
Unassuming “Swiss Army knife”-like protein proves lynchpin in a new cancer drug’s therapeutic action
News
Research
Researchers report a surprising mechanism through which an important new candidate drug against leukemia exerts its therapeutic effect....
High School students support pancreatic cancer research in a big way
Blog
Research
Local high school students raise over $3,500 for pancreatic cancer research during the Long Island Pancreatic Cancer Research Walk....
Masthead Cove Yacht Club raises over $7000 for CSHL cancer research at annual race
News
Giving Institutional
Members of the Masthead Cove Yacht Club (MCYC) raised $7,124 from their annual Masthead Race....
Movember: Fighting for health in the Lab and the gym
Blog
Research
Dawid Nowak discusses the difficulties and challenges involved in understanding pancreatic cancer....
Regeneron’s Dr. George D. Yancopoulos elected to Cold Spring Harbor Laboratory Board of Trustees
News
Institutional
Cold Spring Harbor Laboratory announced the election of George D. Yancopoulos, M.D., Ph.D to its Board of Trustees....
Addition of sugars plays a key developmental role in distantly related plants
News
Research
Researchers found deleting the genes for enzymes in two plants widely separated in evolutionary time resulted in similar defects....
Breast cancer survivors show Camila dos Santos what’s important about her research
Blog
Research
Camila dos Santos talks about what she has learned by talking with breast cancer survivors....
10th Double Helix Medals Dinner raises record $4.5 million for biomedical research at Cold Spring Harbor Laboratory
News
Giving Institutional
The 10th Double Helix Medals dinner honored Katie Couric, Anne Wojcicki and David Botstein, champions of research to benefit mankind....
Student wins 1st Breakthrough Junior Challenge prize and his school gets a new state-of-the-art science lab designed by CSHL
News
Education
High school senior Ryan Chester was awarded the first-ever Breakthrough Junior Challenge prize....
Finding huge promise in a single cell with student Robert Aboukhalil
News
WSBS
Robert Aboukhalil use his skills as a computational biologist to make single-cell genomic data easy for scientists and clinicians to access and use....
Breaking down breast cancer at CSHL
Blog
Research
A look at how several researchers at CSHL contribute to the field of breast cancer research....
Who (else) was at Banbury in 1989 setting the stage for the Human Genome Project?
Blog
Education History
A historical look back at the 1989 meeting at the Banbury Center which sparked the idea of the Human Genome Project....
Long Island man continues the fight against breast cancer in memory of his fiancé
News
Giving
Michael Maringo established the Carissa Maringo Fund to support breast cancer research at Cold Spring Harbor Laboratory...
Rhabdomyosarcoma (RMS) research bolstered by $50,000 gift from Friends of TJ
News
Giving Institutional
The Friends of TJ Foundation presented a check for $50,000 to CSHL Associate Professor Chris Vakoc...
Ride For Life gives $300,000 for ALS research at Cold Spring Harbor Laboratory (CSHL)
News
Giving Institutional
ALS Ride For Life this month presented $300,000 to CSHL Assistant Professor Molly Hammell and Associate Professor Josh Dubnau...
Introducing the mighty Panoramix–defender of genomes!
News
Research
Scientists have identified a protein the Piwi system uses to guide a cell's gene-silencing machinery to the right spots in the genome....
Breast Cancer Awareness Month: Mary-Claire King’s trailblazing research
Blog
Research
A look at the career of Mary-Claire King a geneticist who worked on the causes of breast cancer....
Approach or buzz off: brain cells in fruit fly hold secret to individual odor preferences
News
Research
Scientists have discovered the point at which incoming sensory information begins to transform into a neural signal that instructs a fly's response....
CSHL Fellow wins 2015 NIH Early Independence Award for cancer research
News
Research
CSHL Lab Fellow Jason Sheltzer won the 2015 Early Independence Award from the National Institutes of Health High Risk, High Reward Research Program...
The Human Genome Project opened a new era of science
Blog
Education History
A look back at the start of the Human Genome Project and CSHL's James Watson's role in it....
Research connects specific variations in RNA splicing with breast cancer causation
News
Research
Researchers have identified cellular changes that may play a role in converting normal breast cells into tumors....
14th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory
News
Giving Institutional
Cold Spring Harbor Laboratory (CSHL) held the 14th annual Women's Partnership for Science luncheon....
Genetic analysis supports prediction that spontaneous rare mutations cause half of autism
News
Research
Scientists find evidence suggesting that devastating “ultra-rare” mutations play a causal role in roughly half of all autism spectrum disorders....
Scientists sequence genome of worm that can regrow body parts, seek stem cell insights
News
Research
Worm’s genome could lead to better understanding of its regenerative prowess and advance stem cell biology....
Research bench to writing desk with alum Darren Burgess
News
WSBS
A look at the career of an editor at a prestigious scientific journal....
What’s behind million-dollar crop failures in oil palm? Would you believe bad karma?
News
Research
A way to prevent damaged plantlets from being grown, to boost yield and reduce tropical land pressure....
Dr. Evelyn Witkin, ‘golden age’ Cold Spring Harbor geneticist, wins Lasker at age 94
News
Institutional
Dr. Evelyn Witkin was honored at age 94 with a Lasker Award for achievement in Basic Science...
Mathematical ‘Gingko trees’ reveal mutations in single cells that characterize diseases
News
Research
Online app could help clinicians choose the best treatments by comparing genetic fingerprints of individual cells...
Scientific inspiration with third-year student Annabel Romero Hernandez
News
WSBS
Graduate student Annabel Romero Hernandez spent 244 days portraying the world around her on a very small scale....
Stand Up for Suzanne to hold fundraiser in support of breast cancer research at CSHL
News
Giving
Stand Up for Suzanne to hold fundraiser in support of breast cancer research at CSHL...
12th annual LI2DAY Walk raises over $400,000
News
Institutional
The $19,000 donation received by CSHL will support breast cancer research in the laboratory of Professor Alea Mills....
CSHL’s 22nd annual golf tournament raises $230,000 for research and education
News
Giving
184 golfers took to the greens at Piping Rock Club for Cold Spring Harbor Laboratory's 22nd annual golf tournament...
Surprised? Cholinergic neurons send brain-wide broadcasts enabling us to learn from the unexpected
News
Research
Researchers find dedicated neurons that rapidly informing multiple subregions in the brain of any surprising rewards or punishments....
Continuing Professional Education course to be held at CSHL on 10/6/15
News
Giving
2 credit continuing education class for accountants on Estate Planning will be held at Cold Spring Harbor Laboratory on 10/6/15....
Swim Across America fundraiser supports lung cancer research at CSHL
News
Giving
Swim Across America held its annual "Cove to Sound" swim at Morgan's Park in Glen Cove, NY on August 8, 2015...
Third-year student Abram Handly Santana explores the pancreatic tumor microenvironment
News
WSBS
Abram Handly Santana wants to understand how the tumor microenvironment contributes to pancreas cancer...
In mice, an experimental drug treatment for Rett syndrome suggests the disorder is reversible
News
Research
A team at Cold Spring Harbor Laboratory find a new approach for treating Rett syndrome, a devastating autism spectrum disorder...
Joni Gladowsky Breast Cancer Foundation donates $80,000 to Cold Spring Harbor Laboratory
News
Giving
These proceeds will support breast cancer research in the laboratory of CSHL Professor Nicholas Tonks....
Painting a colorful path of support for autism research
Blog
Education Giving
Stephanie de Lesseps organizes a color run that earned $10,000 for autism research at CSHL....
Luis A. Mejia, Ph.D., is named 2015 Arnold O. Beckman Postdoctoral Fellow
News
Institutional
Mejia will receive funding for at least two years from the Foundation, works in the laboratory of Dr. Bo Li...
Alumna Elizabeth Murchison follows the evolutionary path of contagious cancer
News
WSBS
Watson School of Biological Science ‘07 alumna Dr. Elizabeth Murchison studies cancers in domestic dogs, soft-shell clams and Tasmanian devils...
The biggest beast in the Big Data forest? One field’s astonishing growth is, well, ‘genomical’!
News
Research
Scientists work to figure out how to capture, store, process and interpret all that genome-encoded biological information....
Alumna Monica Dus discovers the cookie-brain connection
News
WSBS
A look at alumna Dr. Monica Dus....
Revised view of brain circuit reveals how we avoid being overwhelmed by powerful odors
Research
Researchers discover neural circuit in the mouse olfactory bulb that shows how our mammalian cousins adjust to intense odors....
July 7, 1890 – Official start of first course at the Laboratory
News
Institutional
July 7 marks the first day of the first course given at The Brooklyn Institute's Laboratory of Biological Research at Cold Spring Harbor Laboratory. ...
Lending a shore to fellow LI researchers
Blog
Research
Long Island University - Post and Adelphi University researchers team up with CSHL to study the Asian shorecrab....
Third-year student Tyler Garvin brings together engineering and medicine to help save lives
News
WSBS
Student researches non-coding mutations responsible for changes in human gene expression....
Joni Gladowsky Breast Cancer Foundation donates $20,000 to CSHL
News
Giving
The event was held at Syosset-Woodbury Community Park and included a Junior Outdoor Hockey Game, an Adult Outdoor Hockey Game and 2 Family Open Skates...
From the Laboratory of Barbara McClintock–Nobel tools inspire award-winning art
Blog
History Institutional
Celebrating Barbara McClintock's birthday with a painting by Elizabeth Turnbull inspired by the Nobel laureate....
125th Anniversary Open House draws hundreds to explore Cold Spring Harbor Laboratory
News
Institutional
Over 600 people converged on CSHL this past Saturday for the Laboratory’s 125th Anniversary Open House....
Alumnus Niraj Tolia works toward a modern malaria vaccine
News
WSBS
Alumnus receives five-year Investigators in the Pathogenesis of Infectious Disease Burroughs Wellcome Fund grant to fight malaria...
An immune system marker for therapy-resistant prostate cancer
News
Research
Research shows how signaling by an immune system component appears to play an important role in driving particularly aggressive prostate cancer...
Neuroscientists discover how feedback from the cortex helps mammals make fine distinctions about odors
Research
Researchers study the feedback loop of the olfactory bulb sends output to and receives feedback from multiple parts of the brain...
Pershing Square Foundation establishes $10 million endowment to support CSHL life science research
News
Giving Institutional
The uniquely structured grant reflects a commitment by The Pershing Square Foundation to support exceptional leadership and innovative organizations....
“Science is our candle in the dark”
Blog
Education WSBS
The remarks of Jack Walleshauser at the 2015 Watson School of Biological Sciences graduation....
Tumor surroundings are shown to affect progression of different cancer subtypes
News
Research
Researchers discover that cancer progress differently based on characteristics of the tumor microenvironment....
Scientists pinpoint genes that make stem cells in plants, revealing origin of beefsteak tomatoes
News
Research
Researchers identified a set of genes that control stem cell production in tomato, which affects its size....
Dr. Marja Timmermans, plant geneticist, begins Alexander von Humboldt Professorship in Germany
News
Institutional
Timmermans was one of five foreign researchers awarded an Alexander von Humboldt Professorship ...
Scientists discover how a promising anti-leukemia drug harms cancer cells
News
Research
Inhibiting a protein called BRD4 critical to the survival of acute myeloid leukemia (AML) cells has shown to be an effective therapeutic strategy....
Drs. Kepecs and Li honored with 2015 NARSAD Independent Investigator grant awards
News
Research
Dr. Kepecs and Dr. Li received two-year grants to fund their important research....
Using CRISPR, biologists find a way to comprehensively identify anti-cancer drug targets
News
Research
Researchers use CRISPR to find binding pockets inside cancer cells, that when blocked, prevent the cells from proliferating and cause them to die....
Scientists show the mammary gland ‘remembers’ prior pregnancy, spurring milk production
News
Research
Anecdotal reports of nursing mothers have long suggested that giving milk is a lot easier in second and subsequent pregnancies....
Report shows Cold Spring Harbor Laboratory’s research and education power Long Island, State economies
News
Institutional
CSHL annually generates $150 million in economic output and accounts for 1,629 jobs and $93 million in earnings; more expected in the future...
WSBS Teaching Award 2015 for Bo Li
News
WSBS
Associate Professor Bo Li wins the Winship Herr Award in 2015....
New signaling pathway discovered in HER2-positive breast cancer, and two potentially powerful drug targets
News
Research
Rsearchers discovered a new pathway, which contains at least two potentially powerful drug targets...
Cold Spring Harbor Laboratory’s 12th commencement ceremony to honor science advocates
News
Education WSBS
Charlie Rose, Dr. Hanna Gray, Lord David Sainsbury receive honorary degrees...
Graduation 2015
News
WSBS
Sunday, April 19, marks the 12th Watson School commencement, and fittingly, we are awarding twelve Ph.D. degrees....
Cancer researcher Dr. Chris Vakoc to receive AACR’s Outstanding Achievement Award
News
Institutional
Assistant Professor Christopher R. Vakoc, receives the 35th annual AACR Outstanding Achievement in Cancer Research Award...
WSBS Dean Alexander Gann awarded Guggenheim Fellowship in science writing
News
Institutional WSBS
Alexander Gann has been awarded a 2015 Guggenheim Fellowship in science writing....
Study revises standard theory of how PTEN, a critical tumor suppressor, shuts off growth signals
News
Research
Scientists discover new evidence explaining precisely how the protein encoded by PTEN (called PTEN) works...
One experiment: Cellular highways carry anti-cancer cargoes
Feature
Research
The gene called PTEN is one of the most important of the body’s natural tumor suppressors....
Thinking about cognition with recent graduate Kristen Delevich
News
WSBS
Watson School graduate Kristen Delevich studies how different brain regions communicate with one another ...
Tumor cells that mimic blood vessels could help breast cancer spread to other sites
News
Research
“Vascular mimicry” observed in mice could be helping tumors evade anti-angiogenesis drugs...
Scientists discover important communication mechanism between two brain areas implicated in schizophrenia
News
Research
Researchers discover an inhibitory connection between certain brain areas that can control the timing of information flow to the prefrontal cortex ...
Cold Spring Harbor Laboratory thanks Nobelist James Watson for $1 million donation
News
Giving Institutional
Dr. Watson donates $1million to the Laboratory in support of biomedical research and education programs....
Cold Spring Harbor Laboratory and North Shore-LIJ announce strategic affiliation to accelerate benefits of cancer research to patients
News
Institutional
Cold Spring Harbor Laboratory and the North Shore-LIJ Health System announced a strategic affiliation....
Swartz Centers Dedication
News
Giving
An official recognition of Jerome Swartz for his 25+ years of friendship and generous support of Cold Spring Harbor Laboratory neuroscience programs ...
Local business raises over $10,000 for Cold Spring Harbor Laboratory breast cancer research
News
Giving Institutional
Aboff’s presented a check this month for $10,107 to Cold Spring Harbor Laboratory for breast cancer research....
Cold Spring Harbor Laboratory engages Hairpin Technologies Inc. to license its short hairpin RNA (shRNA) technology
News
Institutional
Cold Spring Harbor Laboratory engaged Hairpin Technologies Inc. to expand the commercial distribution and research use of short hairpin RNA....
When thinking about numbers, people estimate a range rather than a single value
News
Research
Representing numbers as a range of possible values allows people to utilize multiple streams of information, leading to improved decisions...
A unique partnership
Blog
Education Research
The story of a high school student working with Michael Schatz to create an app that analyzes DNA....
Cold Spring Harbor Laboratory and GSK to develop diabetes and obesity therapeutic
News
Institutional Research
CSHL announced a collaboration with GSK to develop a treatment for obesity and type 2 diabetes....
Long Island Ph.D. student wins 2015 Harold M. Weintraub award
News
Institutional WSBS
Ian Peikon is the 4th Cold Spring Harbor Laboratory graduate student to win the Harold M. Weintraub award...
LI pharma executive joins Cold Spring Harbor Laboratory as General Counsel
News
Institutional
Charles S. Ryan joins CSHL as the Laboratory’s new General Counsel...
Cancer metabolism and country music with first-year student Jackie Giovanniello
News
WSBS
Student Jackie Giovanniello works to develop better treatment options for patients....
Twin copies of a gene pair up in embryonic stem cells at a critical moment in their differentiation
News
Research
Team finds that both copies of the Oct4 gene come together just as embryonic stem cells begin to develop into tissue-specific cell types...
22nd Annual Golf Tournament to be held June 16
News
Giving
Cold Spring Harbor Laboratory honors Trudy and Tom Calabrese and celebrates its 22nd Annual Golf Tournament at Piping Rock Club...
Mind-readers: scientists crack a piece of the neural code for learning and memory
Research
Postmortem brain slices can be “read” to determine how a mouse was trained to behave in response to specific sounds ...
Join CSHL’s TEAM and raise money for breast cancer research
Giving
Join CSHL's TEAM and raise money for breast cancer research...
Stand Up for Suzanne holds breast cancer fundraiser for CSHL
News
Giving
Stand Up for Suzanne held its 2nd annual fundraiser at The Milleridge Cottage....
CSHL quantitative biologist Michael Schatz awarded 2015 Sloan Foundation Research Fellowship
News
Research
Associate Professor Michael Schatz receives a 2015 Alfred P. Sloan Foundation Research Fellowship...
Joni Gladowsky Breast Cancer Foundation donates $60,000 to CSHL
News
Giving
Cold Spring Harbor Laboratory is the proud recipient of proceeds from the Joni Gladowsky Breast Cancer Foundation's Tenth Annual Golf Outing...
Making decisions with fourth-year student Kachi Odoemene
News
WSBS
Student Kachi Odoemene works on studying repression of neuronal activity and contributes to decision-making...
Girls who code (at Cold Spring Harbor)
Blog
Education WSBS
Cold Spring Harbor Laboratory joins with Girls Who Code to empower girls into a future in STEM and technology....
In a role reversal, RNAs proofread themselves
News
Research
Molecular photographs of an enzyme bound to RNA reveal a new, inherent quality control mechanism...
Christina Renna Foundation Raises $30,000 for pediatric cancer research at CSHL
News
Giving Institutional
The Christina Renna Foundation presented $30,000 to Cold Spring Harbor Laboratory (CSHL) at their 8th annual Angel's Wish Gala...
Harnessing data from Nature’s great evolutionary experiment
News
Research
Scientists develop a computational method to estimate the importance of each letter in the human genome...
Fighting pediatric cancer
Blog
Research
A discussion on the mission of Christina Renna Foundation and its fight against pediatric cancers....
A new brain circuit that controls fear is identified
News
Research
Researchers discover a pathway in that mouse brain that regulates fear memory and behavior ...
3D culture system for pancreatic cancer has potential to change therapeutic approaches
News
Research
Organoid technology with human tissue provides a model for full progression of the disease...
Mechanistic insights into spinal muscular atrophy suggest new paths for treatment
News
Research
Researchers find that in mouse models of the disease subcutaneous drug administration is sufficient to treat SMA ...
New research on what the nose ‘knows’ reveals an unexpected simplicity
Research
In rats, olfactory bulb neurons use simple ‘linear summation’ to make sense of fluctuating odor inputs from the surrounding environment...
A novel biomarker for mutant p53 could help pathologists assessing tumors during surgery
News
Research
New discovery may make it easy for cancer surgeons to determine if a patient has a potentially lethal mutation....
Imaging method linking brainwide cell activation & behavior shows what it means for mice to have sex in mind
News
Research
Automated method detects activity of neurons during specific behaviors, brainwide, at cellular resolution...
Manhasset Women’s Coalition Against Breast Cancer raises $100,000 to support breast cancer research at CSHL
News
Giving Institutional
Manhasset Women’s Coalition Against Breast Cancer raises $100,000 to support breast cancer research...
Pink Ribbon Bagels bring nearly $8,500 for breast cancer research at CSHL
News
Giving Institutional
The Breast Cancer Research Program as among the beneficiaries of this year's annual Pink Ribbon Bagel campaign....
Neuronal circuits filter out distractions in the brain
News
Research
Scientists identify a neural pathway that controls attention, with implications for psychiatric disorders ...
Three new trustees elected to Cold Spring Harbor Laboratory Board
News
Institutional
The Board of Directors of Cold Spring Harbor Laboratory (CSHL) elected three new trustees at its November 2014 meeting....
RNA and U with fifth-year student Jack Walleshauser
News
WSBS
Jack Walleshauser wins the student poster prize at the 2014 in-house symposium....
CSHL team finds a way to make shRNA gene knockdown more effective
News
Research
Scientists devised a powerful algorithm that improves the effectiveness of research technology harnessing RNA interference ...
One experiment: McClintock’s historic discovery
Feature
Research
Four decades after this photo was taken, a Nobel Prize was awarded to McClintock, acknowledging her discovery that genetic material is not fixed...
Variation in expression of thousands of genes is kept under tight constraint in mice and humans, in all cells and tissues
Research
Researchers have identified some 6600 genes whose level of expression varies within a comparatively restricted range in humans and mice...
New investigators join CSHL
Blog
Research
An interview with newly hired investigators Scott Lyons and Lingbo Zhang....
Double Helix gala raises record $4 million for biomedical research at Cold Spring Harbor Laboratory
News
Giving Institutional
More than $4 million was raised the evening of November 12 for Cold Spring Harbor Laboratory’s (CSHL) research and education programs....
New junior faculty join CSHL
Blog
Research
Interviews with new junior faculty members Jessica Tollkuhn and Je Lee...
New senior faculty join CSHL
Blog
Research
Interviews with new faculty Adam Siepel and Douglas Fearon....
Re-learning how to read a genome
Research
Study suggests a unified model for how DNA is read, offering insight into how genes evolve...
Some neurons can multitask, raising questions about the importance of specialization
Research
New findings challenge assumptions about how information is encoded in the brain...
Mapping the brain with recent graduate Ian Peikon
News
Education WSBS
Ian Peikon, inventor of DIATROL, looks to map all the connections between all of the neurons in the entire brain....
Getting more out of Nature: genetic toolkit finds new maximum for crop yields
Research
An array of gene variants provides “breakthrough benefits” in tomato yield for breeders; other crops next...
Election Day: making medical research a priority
Blog
Institutional
CSHL partnered Research!America in a bipartisan effort to find out where political candidates stand on research funding....
Cold Spring Harbor Laboratory faces off against a rare cancer with launch of Sarcoma Research Project
News
Giving Institutional
CSHL is launching a highly targeted effort to combat a rare and deadly type of sarcoma called rhabdomyosarcoma....
Missing sponge gene is found at ‘ghost’ site, proving our oldest common ancestor was more complex than believed
Research
The last common ancestor of all animals, some 600 million years old, was not as primitive as most experts have assumed....
New study casts sharpest light yet on genetic mysteries of autism
News
Research
Our picture of how genetic errors contribute to autism has just gotten sharper....
Experts convene at CSHL to scrutinize, assess low-dose CT screening for lung cancer
Research
Nearly two dozen physicians and researchers took a close scientific view of lung cancer progression for diagnostic purposes....
How a molecular Superman protects the genome from damage
News
Research
Scientists find a new role for RNAi protein Dicer in preventing collisions during DNA replication....
In a battle of brains, bigger isn’t always better
Research
Scientists are surprised to find that rats and mice perform similarly in cognitive tests....
Universe to smelliverse with second-year student Daniel Kepple
News
WSBS
Daniel Kepple hopes to figure out the chemical and neuronal rules that determine what something smells like...
Rally for medical research Capitol Hill Day
Blog
Research
Cristina Aguirre-Chen, Ph.D., a postdoc in Assistant Professor Chris Hammell’s lab discusses her experience at the Rally for Medical Research....
4 CSHL scientists will contribute to President’s BRAIN Initiative under new NIH grants
News
Research
Four scientists at Cold Spring Harbor Laboratory (CSHL) will perform research in President Obama’s BRAIN Initiative under two new CSHL grants...
Masthead Cove Yacht Club raises $9,500 for CSHL cancer research at annual race
News
Giving Institutional
The proceeds were donated to support cancer research conducted by CSHL Professor Nicholas Tonks. ...
13th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory
News
Giving Institutional
CSHL neuroscientist Dr. Anne Churchland delivers keynote on decision-making ...
Gambling with confidence: Are you sure about that?
News
Research
Scientists uncover the neural basis of confidence in the rat brain...
Scientists looking across human, fly and worm genomes find shared biology
Research
Researchers found that human, fly, and worm genomes have a number of key genomic processes in common, reflecting their shared ancestry....
Welcome to the Watson School
Blog
Education WSBS
A graduate student from the Watson School of Biological Sciences talks about the school's history and programs....
11th annual LI2DAY Walk raises over $525,000 for breast cancer
News
Giving Institutional
Cold Spring Harbor Laboratory and 17 other breast cancer beneficiary groups received over $525,000 in funding for breast cancer research....
New understanding of a mechanism by which cells try to arrest oncogene action
News
Research
What happens inside cells when they detect the activation of a cancer-inducing gene? ...
CSHL’s Florin Albeanu, Partha Mitra awarded NSF ‘Early Concept’ grants for neuroscience
Institutional
Award supports exploratory research with potential for transformative insights – part of BRAIN Initiative...
A shift in the code: new method reveals hidden genetic landscape
News
Research
Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD...
More than just X and Y: a new genetic basis for sex determination
Research
Researchers identify microRNAs that differentiate male and female fruit flies...
Knowing what to keep and what to trash: how an enzyme distinguishes cellular messages
Research
Molecular structure reveals how a protein reads RNAs to preserve stem cell identity ...
CSHL quantitative biologist Michael Schatz wins prestigious NSF Early CAREER Award
News
Institutional Research
The National Science Foundation (NSF) has selected Assistant Professor Michael Schatz, Ph.D to receive its prestigious CAREER Award....
Research may explain how the body’s foremost anti-cancer ‘guardian’ protein learned to switch sides
News
Research
Researchers have discovered a new function of the body’s most important tumor-suppressing protein....
“When I grow up…”
Blog
Education
Today, scientists at Cold Spring Harbor Laboratory are working with the community to make sure that kids are exposed to research at a young age...
In development, it’s all about the timing
News
Research
Closely related organisms share most of their genes, but these similarities belie major differences in behavior, intelligence, and physical appearance...
Scientists propose how antioxidants can accelerate cancers and why they don’t protect against them
Research
In several trials, antioxidant supplementation has been linked with increased rates of certain cancers....
A summer splicing with first-year student Lital Chartarifsky
News
WSBS
Lital Chartarifsky, a former URP, and her journey to neuroscience research....
21st annual golf tournament raises over $270,000 for research and education at CSHL
News
Giving Institutional
Laboratory Trustee Ed Travaglianti honored for longstanding service at annual golf outing....
CSHL receives $50 million to establish Simons Center for Quantitative Biology
News
Institutional
CSHL announced a $50 million gift from Jim and Marilyn Simons to establish the Simons Center for Quantitative Biology....
CSHL’s Dr. Molly Hammell named 2014 Rita Allen Foundation Scholar
News
Institutional
Dr. Hammell wins an award for young investigators for innovative biomedical research...
CSHL’s Anne Churchland named Pew Scholar and Klingenstein-Simons Fellow
News
Research
Dr. Churchland receives award that honors excellence in neuroscience and biomedical research ...
Neuroscientists explain how mutated X-linked mental retardation protein impairs neuronal function
News
Research
There are new clues about malfunctions in brain cells that contribute to intellectual disability and possibly other developmental brain disorders. ...
Big Data meets DNA
Blog
Research
Postdoctoral researcher Michael Hübner discusses how big data is being used in genomics and disease research....
CSHL breast cancer researcher Mikala Egeblad wins DoD Era of Hope Scholar Award
News
Institutional Research
Dr. Egeblad receives a multi-year, $2.5 million Department of Defense grant to advance cutting-edge breast cancer research ...
High school students learn the fascinating story of Henrietta Lacks
Blog
Education
CSHL Director of Research Professor David Spector discusses his visit to the Horace Mann School....
Cold Spring Harbor Laboratory announces settlement in patent malpractice case against Ropes & Gray
Institutional
CSHL ramps up licensing of its short-hairpin RNA technology already used widely in cancer research and drug development...
One experiment: Sometimes our cells express only one gene copy. Why?
Feature
Research
Professor David L. Spector and team discover some monoallelically expressed genes encoded extra RNA, even though they are missing their other gene....
Unprecedented detail of intact neuronal receptor offers blueprint for drug developers
News
Research
NMDA receptor malfunction is implicated in Alzheimer’s, Parkinson’s, depression, schizophrenia, autism, and stroke...
Dealing with stress—to cope or to quit?
News
Research
Researchers identify neurons that determine whether an individual will be depressed or resilient ...
Searching for cancer cures with first-year student Georgi Yordanov
News
WSBS
Student Georgi Yordanov looks to study how cancer cells communicate with the normal cells surrounding them in a tumor....
Putting together the genome with first-year student Maria Nattestad
News
WSBS
Student Maria Nattestad looks to develop a fast and accurate way of putting short DNA sequences back together into the long, linear sequences...
Watson School Graduation 2014
News
WSBS
11 students graduate from the Watson School of Biological Sciences...
Team reports validation of potentially powerful new way to treat HER2-positive breast cancer
News
Research
Researchers report a discovery that they hope will lead to the development of a powerful new way of treating an aggressive form of breast cancer....
A bad neighborhood for cancer
Blog
Research
Miriam Fein, a graduate student working in Egeblad lab, ...
Male infertility: it’s all about the package
Research
Scientists find a protein that controls DNA organization during sperm development ...
Dr. David Spector, CSHL Professor, is elected to European Molecular Biology Organization
Institutional
European Molecular Biology Organization, has elected CSHL Professor David L. Spector, Ph.D., to its ranks....
Watson School of Biological Sciences celebrates 15th year, confers Ph.D.s on 11th graduating class
News
Institutional WSBS
Watson School celebrates its 15th classes graduation, and Dr. Richard Burgess is awarded an honorary degree ...
Lloyd Trotman receives Pershing Square Sohn Prize for Cancer Research
News
Institutional
Associate Professor Award encourages young investigators to take risks in search of a cure...
Finding the genes that underlie autism
Blog
Research
Research Assistant Professor Mike Ronemus talks about the importance of understanding the genetics of autism....
Research sees overlap in altered genes found in schizophrenia, autism and intellectual disability
News
Research
New evidence supports theory that some cases of schizophrenia and autism have malfunctions in some of the same genes are contributing to pathology....
CSHL’s Dr. David Spector is elected to the American Academy of Arts and Sciences
News
Institutional Research
Professor David L. Spector, Ph.D. has been elected to the American Academy of Arts and Sciences....
Dr. Bruce Stillman, CSHL President, wins 2014 Herbert Tabor Research Award
News
Institutional
Dr. Bruce Stillman, President of Cold Spring Harbor Laboratory (CSHL), is the 2014 winner of the Herbert Tabor Research Award....
An interview with cancer’s ‘biographer’
Blog
Research
An interview with The Emperor of Maladies author Siddartha Mukherjee...
National Science Foundation-sponsored CureNet and CSHL team to improve undergrad research in biology
News
Education
More than 100 faculty and administrators meet to discuss how to involve more undergraduate students in science research....
Don Monti Memorial Research Foundation gives $500,000 for cancer research at CSHL
News
Giving Institutional
President of the Don Monti Memorial Research Foundation presented Cold Spring Harbor Laboratory with a donation of $500,000....
Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood
Research
New research indicates a link between certain kinds of early stress and dysfunction in the neuroendocrine system....
For neurons in the brain, identity can be used to predict location
Research
A new mathematical model uses gene expression data to predict where neurons are located throughout the brain...
Newly identified small-RNA pathway defends genome against the enemy within
Research
microRNAs are found to target ‘jumping genes’ in reproductive cells, protecting against genomic damage...
Celebrating Brain Awareness Week with DNALC’s 3D Brain–revolutionizing education in the classroom and the doctor’s office
Blog
Education Research
The 3D Brain app is an interactive, three-dimensional model of the human brain...
Unravelling a mystery in the ‘histone code’ shows how gene activity is inherited
News
Research
Why is histone H3.3 associated with active genes, but histone H3.1 is not?...
What makes a great scientist tick?
Blog
Education Research
Cold Spring Harbor High School student Skyler Palatnick interviews David L. Spector on his career as a cancer researcher....
Ohr Pharmaceutical and CSHL Announce Joint Venture to Develop Trodusquemine and Related Analogs
News
Institutional
Ohr Pharmaceutical and CSHL announce a new joint venture to develop trodusquemine and related analogs....
CSHL lung cancer researcher receives $70,000 from Swim Across America-Nassau Suffolk
News
Giving Institutional
Swim Across America (SAA) Nassau Suffolk Committee distributed the net proceeds of its 2013 Swims to six Long Island and metro area beneficiaries....
Research reveals first glimpse of a brain circuit that helps experience to shape perception
Research
For the first time, scientists monitor inhibitory neurons that link sense of smell with memory and cognition in mice...
Nobelist James Watson proposes an unconventional view of type 2 diabetes causation
Research
A new hypothesis of type 2 diabetes causation published in the British medical journal The Lancet...
Like mom or like dad? Some cells randomly express one parent’s version of a gene over the other
Research
Team finds that some cells activate only one of their two gene copies during development, altering protein yields and raising new questions...
Researchers propose new way to make sense of ‘Big Data’
News
Research
New application of a classic concept challenges the latest statistical tools....
Scientists discover a new pathway for fear deep within the brain
News
Research
‘Far-reaching’ neurons connect the amygdala with fear response center to control behavior...
Scientists develop powerful new animal model for metastatic prostate cancer
Research
The new model, known as RapidCaP, reveals a cancer-gene ‘switch’ that drives metastasis ...
Unprecedented structural insights reveal how NMDA receptors can be blocked, to limit neurotoxicity
Research
Structural biologists have obtained important scientific results likely to advance efforts to develop new drugs targeting NMDA receptors in the brain...