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Science self-corrects: cancer gene does not pass reproducibility test

Science self-corrects: cancer gene does not pass reproducibility test

February 13th, 2018

News
Research

CSHL Fellow Jason Sheltzer and his research team use CRISPR to discover that MELK is not actually involved in cancer....

Autism genetics study calls attention to impaired motor skills, general cognitive impairment

Autism genetics study calls attention to impaired motor skills, general cognitive impairment

February 7th, 2018

News
Research

New research on the genetic causes of autism calls attention to diminished motor skills and suggests the importance of broad cognitive impairment...

PLOS and CSHL enter agreement to enable preprint posting on bioRxiv

PLOS and CSHL enter agreement to enable preprint posting on bioRxiv

February 6th, 2018

News
Institutional

The Public Library of Science (PLOS) will now be automatically posting papers submitted to its journal on bioRxiv, CSHL's preprint server...

Welcome to the real world of science, I’ll be your guide

Welcome to the real world of science, I’ll be your guide

February 5th, 2018

Blog
Institutional

Jackie Novatt was determined to show the people on her campus tours how science really works—and landed her dream job in the process....

Dr. Leemor Joshua-Tor honored with Mildred Cohn Award from ASBMB

Dr. Leemor Joshua-Tor honored with Mildred Cohn Award from ASBMB

February 2nd, 2018

News
Institutional

Professor Leemor Joshua-Tor receives the American Society for Biochemistry and Molecular Biology’s 2018 Mildred Cohn Award in Biological Chemistry....

More rice, please: 13 rice genomes reveal ways to keep up with ever-growing population

More rice, please: 13 rice genomes reveal ways to keep up with ever-growing population

February 1st, 2018

News
Research

Rice provides 20% of calories consumed. As the population grows toward 9 billion and the climate shifts, we'll need to grow more rice in more places....

At CSHL, Congressman Suozzi celebrates scientific achievements of local HS students

At CSHL, Congressman Suozzi celebrates scientific achievements of local HS students

January 29th, 2018

News
Education

Congressman Suozzi hosts congratulatory event at CSHL for high school science competition winners, including two Partners for the Future participants...

Evolving sets of gene regulators explain some of our differences from other primates

Evolving sets of gene regulators explain some of our differences from other primates

January 29th, 2018

News
Research

What makes us different from our primate relatives? Gene regulation is one important evolutionary factor...

New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes

New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes

January 26th, 2018

News
Research

CSHL scientists have designed software that enables biologists to determine with unprecedented accuracy how much protein a given cell is making...

45 years later, a scientist realizes he’s a star

45 years later, a scientist realizes he’s a star

January 24th, 2018

Blog
Education

David Haas was stunned to learn the impact of work he abandoned decades ago. He took a CSHL course to see it for himself....

Christina Renna Foundation raises $30,000 for continuing pediatric cancer research at CSHL

Christina Renna Foundation raises $30,000 for continuing pediatric cancer research at CSHL

January 22nd, 2018

News
Giving Institutional

The Christina Renna Foundation donates over $30,000 for rhabdomyosarcoma research, and honors Associate Professor Chris Vakoc with its research award...

CSHL’s Rob Martienssen honored with prestigious Barbara McClintock Prize

CSHL’s Rob Martienssen honored with prestigious Barbara McClintock Prize

January 19th, 2018

News
Institutional

Plant geneticist Rob Martienssen awarded prestigious McClintock Prize...

Counting chromosomes: Plant scientists solve a century-old mystery about reproduction

Counting chromosomes: Plant scientists solve a century-old mystery about reproduction

January 18th, 2018

News
Research

Geneticists have solved a century-old mystery by discovering a remarkable mechanism that enables plants to count their chromosomes...

Turning off the immune system is hard. Turning it on against cancer is easier.

Turning off the immune system is hard. Turning it on against cancer is easier.

January 10th, 2018

Blog
Research

How Professor Doug Fearon’s experiences with autoimmune disease patients contributed to the discovery of a new potential immunotherapy for cancer...

YouTube videos earned her school a new lab from CSHL. Here’s how.

YouTube videos earned her school a new lab from CSHL. Here’s how.

January 10th, 2018

News
Education

Student wins back-to-back prizes from Silicon Valley. One such prize, a lab designed by CSHL’s DNA Learning Center, was awarded to her high school....

Three Strohm Sisters Family Foundation donates $5,000 for research on lung cancer recurrence

Three Strohm Sisters Family Foundation donates $5,000 for research on lung cancer recurrence

January 8th, 2018

News
Giving

On December 18, a representative of the Three Strohm Sisters Family Foundation gave $5,000 for lung cancer recurrence research in Mikala Egeblad's lab...

Molecular decoy helps researchers halt and reverse acute leukemia in mice

Molecular decoy helps researchers halt and reverse acute leukemia in mice

January 8th, 2018

News
Research

By throwing a molecular wrench into the gears of a machine that sets genes into motion, researchers were able to get leukemias to 'melt away.'...

<em>A Cure Within</em> documents the human stories behind cancer immunotherapy

A Cure Within documents the human stories behind cancer immunotherapy

December 28th, 2017

News
Institutional

Immunotherapy as a cancer treatment may be cutting-edge, but it has a history. It’s the result of years of work by many dedicated researchers, some...

CSHL’s Bo Li receives BRAIN Initiative funding

CSHL’s Bo Li receives BRAIN Initiative funding

December 28th, 2017

News
Research

CSHL Professor Bo Li and two collaborators at Oregon Health & Science University (OHSU) have been awarded a new grant under the BRAIN Initiative...

Seahawks help CSHL tackle autism

Seahawks help CSHL tackle autism

December 19th, 2017

News
Giving

CSH Seahawks Varsity football team present Professor Michael Ronemus with a check for $5,000 toward autism research...

A lesson in class

A lesson in class

December 15th, 2017

Feature
Research

In this episode of Base Pairs, we discuss how genetic information is changing how we define important categories....

David Spector is named ASCB Fellow

David Spector is named ASCB Fellow

December 11th, 2017

News
Institutional

David L. Spector was named a fellow of The American Society for Cell Biology...

Dr. Anne Churchland honored with Marshall Award for promoting women in science

Dr. Anne Churchland honored with Marshall Award for promoting women in science

December 11th, 2017

News
Institutional

Associate Professor Anne Churchland was honored with The Louise Hanson Marshall Special Recognition Award...

Next Generation Lyme disease tests found efficacious and ready for clinical arena

Next Generation Lyme disease tests found efficacious and ready for clinical arena

December 7th, 2017

News
Banbury Research

Experts find that current protocols for Lyme disease lacks the accuracy and sensitivity that next-generation testing can provide....

A spot at the podium: The Women in Biology Speakers List

A spot at the podium: The Women in Biology Speakers List

December 5th, 2017

Blog
Education

The gender imbalance in slates of invited speakers for scientific conferences is an issue that CSHL's Women in Science and Engineering (WiSE) group...

New method to determine <em>before</em> surgery which prostate tumors pose a lethal threat

New method to determine before surgery which prostate tumors pose a lethal threat

December 1st, 2017

News
Research

The news about prostate cancer can be confusing. It’s the third most common cancer type among Americans...

Research profile: Leemor Joshua-Tor

Research profile: Leemor Joshua-Tor

November 27th, 2017

Feature
Research

A CSHL faculty member since 1995, a professor since 2005, Joshua-Tor is among the most distinguished members of the Laboratory community....

Next-gen cancer test

Next-gen cancer test

November 24th, 2017

Feature
Research

Knowing that cancers become lethal when they spread, investigators at Cold Spring Harbor Laboratory seek a way of detecting tumors much earlier ...

One experiment: A beautiful brain, neuron by neuron

One experiment: A beautiful brain, neuron by neuron

November 22nd, 2017

Feature
Research

Associate Professor Pavel Osten and colleagues discovered using their qBrain method is discerned by probing hidden relations among the dots....

A transformative partnership

A transformative partnership

November 22nd, 2017

News
Institutional

New York Governor Andrew M. Cuomo visited Cold Spring Harbor Laboratory to break ground on the new $75 million Center for Therapeutics Research....

“Hi, my name is Brian”…“and I’m Andrea”

“Hi, my name is Brian”…“and I’m Andrea”

November 22nd, 2017

News
Research

We’re the hosts of Base Pairs, a podcast from Cold Spring Harbor Laboratory that tells stories about the power of genetic information—past, present an...

Hungry for science

Hungry for science

November 22nd, 2017

News
Giving Institutional

The 12th annual Women’s Partnership for Science luncheon celebrated honorary director of the CSHL Association Freddie Staller....

Double Helix Medals dinner

Double Helix Medals dinner

November 21st, 2017

Feature
Institutional

The 2017 Double Helix Medals were presented to Tom Brokaw and Helen Ann and Charles Dolan....

Welcome back, Dr. Myat

Welcome back, Dr. Myat

November 21st, 2017

News
Education WSBS

Monn Monn Myat, Ph.D., is the new Associate Dean of the Watson School of Biological Sciences....

Additional brain power

Additional brain power

November 21st, 2017

News
Research

For neuroscientists, the brain presents an almost endless number of mysteries to be solved....

Toasting serendipity

Toasting serendipity

November 21st, 2017

News
Research

Four decades ago, scientists made a discovery that “completely transformed all of biology,” according to Nobelist James Watson. ...

Light, cryptochromes, action…

Light, cryptochromes, action…

November 21st, 2017

News
Research

Assistant Professor Ullas Pedmale has received the National Institutes of Health "Outstanding Investigator Award."...

Hannon named director of Cancer Research UK Cambridge Institute

Hannon named director of Cancer Research UK Cambridge Institute

November 21st, 2017

News
Education WSBS

Dr. Greg Hannon has been named the new director of the Cancer Research UK Cambridge Institute, effective February 1, 2018....

12th Double Helix Medals dinner raises $4.5 million for research & education at Cold Spring Harbor Laboratory

12th Double Helix Medals dinner raises $4.5 million for research & education at Cold Spring Harbor Laboratory

November 16th, 2017

News
Giving Institutional

More than $4.5 million was raised last night at Cold Spring Harbor Laboratory’s (CSHL) 12th Double Helix Medals dinner (DHMD)....

Big decisions

Big decisions

November 15th, 2017

Feature
Research

David Micklos of the DNA Learning Center, and Miriam Rich, a research scholar, talk about the big issues of eugenics....

Friends of T.J. present $50,000 gift for ongoing rhabdomyosarcoma research

Friends of T.J. present $50,000 gift for ongoing rhabdomyosarcoma research

November 7th, 2017

News
Giving Institutional WSBS

The Friends of T.J. Foundation presented CSHL Associate Professor Chris Vakoc with a check for $50,000 for his ongoing rhabdomysarcoma research...

Fantastic journey: how newborn neurons find their proper place in the brain

Fantastic journey: how newborn neurons find their proper place in the brain

November 2nd, 2017

News
Research

Neuroscientists have clarified the mechanism used by newly born neurons in mice to migrate to very specific areas....

For brain cells, you are who you speak to

For brain cells, you are who you speak to

October 31st, 2017

Blog
Research

Tracking a person entails searching through their email, phone, and other means of communication to map out their network. To do this for a brain cell...

New leadership roles in BRAIN Initiative and International Brain Lab reflect CSHL’s excellence in neuroscience

New leadership roles in BRAIN Initiative and International Brain Lab reflect CSHL’s excellence in neuroscience

October 24th, 2017

News
Research

The BRAIN Initiative Cell Census Network establishes a Center and a Collaboratory for the Mouse Brain Cell Atlas at Cold Spring Harbor Laboratory ...

Cryo-EM imaging suggests how the double helix separates during replication

Cryo-EM imaging suggests how the double helix separates during replication

October 23rd, 2017

News
Research

Special cryo-EM imaging helps figure out how the double helix of DNA separates when it replicates...

Research revises our knowledge of how the brain learns to fear

Research revises our knowledge of how the brain learns to fear

October 23rd, 2017

News
Research

A team at Cold Spring Harbor Laboratory led by Professor Bo Li found evidence indicating the central amygdala is key to to aversive learning....

One experiment: Bacteria-trapping DNA webs are repurposed by cancer cells

One experiment: Bacteria-trapping DNA webs are repurposed by cancer cells

October 19th, 2017

Feature
Research

Associate Professor Mikala Egeblad discovers that neutrophil extracellular traps (NETs) help cancer by creating holes in the tissue....

Masthead Cove Yacht Club raises over $6000 for CSHL research at annual race

Masthead Cove Yacht Club raises over $6000 for CSHL research at annual race

October 18th, 2017

News
Giving

Members of the Masthead Cove Yacht Club (MCYC) raised $6,700 from their annual Masthead Race on August 13....

Good genes, bad science

Good genes, bad science

October 15th, 2017

Feature
Research

On this episode, Base Pairs looks into the eugenics movement, including the record kept in CSHL....

Governor Cuomo breaks ground on $75 million Cold Spring Harbor Laboratory Center for Therapeutics Research

Governor Cuomo breaks ground on $75 million Cold Spring Harbor Laboratory Center for Therapeutics Research

October 12th, 2017

News
Institutional

NY Governor Andrew M. Cuomo visited Cold Spring Harbor Laboratory (CSHL) this morning to break ground on the new $75 million Center for Therapeutics....

First cell-type census of mouse brains: surprises about structure, male-female differences

First cell-type census of mouse brains: surprises about structure, male-female differences

October 5th, 2017

News
Research

A multiyear project in the Brain Initiative, qBrain is already revealing the brain as never before....

Do neuroscientists need to switch gears to understand how brains make choices?

Do neuroscientists need to switch gears to understand how brains make choices?

October 2nd, 2017

Feature
Research

Associate Professor Anne Churchland, co-founder the IBL along with Professor Tony Zador, explains how it could help solve a problem in neuroscience....

16th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory

16th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory

September 27th, 2017

News
Giving Institutional

Cold Spring Harbor Laboratory held the 16th annual Women's Partnership for Science luncheon, a summer staple among New York's female philanthropists....

Neuron types in the brain are defined by gene activity that shapes their communication patterns

Neuron types in the brain are defined by gene activity that shapes their communication patterns

September 21st, 2017

News
Research

Neurons are defined by determining which cells they connect with and how they communicate across synapses ...

What Silicon Valley and biology research share

What Silicon Valley and biology research share

September 15th, 2017

Feature
Research

Further discussion with Associate Professor Gurinder "Mickey" Atwal about the need for more math and physics in biology....

Plant geneticists develop a new application of CRISPR to break yield barriers in crops

Plant geneticists develop a new application of CRISPR to break yield barriers in crops

September 14th, 2017

News
Research

Mutating regulatory regions varies yield traits the way a dimmer switch controls a light bulb...

Halfway around the world, a reunion of friends opens door to a cancer discovery

Halfway around the world, a reunion of friends opens door to a cancer discovery

August 31st, 2017

Blog
Research

After interviewing for a position in a pancreatic cancer lab at Cold Spring Harbor Laboratory, 7,000 miles from his hometown in South Korea, Chang-il...

Research reveals “exquisite selectivity” of neuronal wiring in the cerebral cortex

Research reveals “exquisite selectivity” of neuronal wiring in the cerebral cortex

August 21st, 2017

News
Research

Inhibitory chandelier cells receive and transmit information from different ensembles of excitatory cells in their cortical neighborhood ...

2nd Annual WiSE Summer Party provides needed networking opportunity

2nd Annual WiSE Summer Party provides needed networking opportunity

August 18th, 2017

News
Institutional

CSHL Women in Science and Engineering and the Postdoctoral Liaison Committee co-hosted the 2nd annual Greater NYC WiSE Summer Beach Party...

Realizing a dream: How a program for undergraduates placed me at the center of CRISPR research

Realizing a dream: How a program for undergraduates placed me at the center of CRISPR research

August 16th, 2017

Blog
Education

Hands-on experience using CRISPR and access to top scientists from around the world who are pioneering its use made this a memorable summer for...

Biology, behind the screens

Biology, behind the screens

August 15th, 2017

Feature
Research

Associate Professor Gurinder "Mickey" Atwal talks about the essential mystery at the center of quantitative biology....

Structural view suggests RNAi machinery multiplies its efficiency in repressing gene expression

Structural view suggests RNAi machinery multiplies its efficiency in repressing gene expression

August 3rd, 2017

News
Research

Leemor Joshua-Tor publishes atomic-resolution pictures and an analysis of RNAi machinery...

CSHL’s Kepecs receives BRAIN Initiative grant to develop tools to guide behavioral research

CSHL’s Kepecs receives BRAIN Initiative grant to develop tools to guide behavioral research

August 1st, 2017

News
Institutional

Dr. Adam Kepecs receives grant to develop conceptual infrastructure for behavioral neuroscience research...

Long-sought mechanism of metastasis is discovered in pancreatic cancer

Long-sought mechanism of metastasis is discovered in pancreatic cancer

July 27th, 2017

News
Research

An epigenetic factor reprograms gene enhancers, enabling cancer cells to “remember” an earlier developmental state and causing metastasis. ...

Team traces masculinization in mice to estrogen receptor in inhibitory neurons

Team traces masculinization in mice to estrogen receptor in inhibitory neurons

July 20th, 2017

News
Research

CSHL researchers discover when ERα receptors are deleted in the brains of male mice, they do not exhibit typical "masculine" behaviors during puberty....

Science and architecture: Back to the future!

Science and architecture: Back to the future!

July 20th, 2017

Blog
History Institutional

3D images are a throwback to the past as CSHL and Centerbrook Architects rediscover a 1950s building that has been occupied by some of the Laboratory...

Library of CRISPR targeting sequences increases power and accuracy of the gene-editing method

Library of CRISPR targeting sequences increases power and accuracy of the gene-editing method

July 20th, 2017

News
Research

New library of RNA sequences that can be used by researchers to direct the CRISPR-cas9 complex to cut DNA with unprecedented precision....

Tomato baby and its family

Tomato baby and its family

July 14th, 2017

Feature
Research

This episode of Base Pairs talks to Associate Professor Zachary Lippman about all the weird mutations that naturally occur in plants....

Eugenics used to be incredibly popular. We can’t let that happen again.

Eugenics used to be incredibly popular. We can’t let that happen again.

July 5th, 2017

Blog
History Institutional

Miriam Rich, the recipient of CSHL’s 2017-18 Sydney Brenner Research Scholarship, is determined to show how the concept of “good genes” became...

Freeze-frames of enzymes in action have implications for a new cancer treatment concept

Freeze-frames of enzymes in action have implications for a new cancer treatment concept

July 3rd, 2017

News
Research

TUTase enzymes interact with let-7, a regulator of development; targeting them could help control certain cancers....

Newly identified small RNA fragments defend the genome when it’s ‘naked’

Newly identified small RNA fragments defend the genome when it’s ‘naked’

June 29th, 2017

News
Research

Fragments snipped from tRNAs protect embryonic stem cells while they’re being epigenetically reprogrammed....

Over $300,000 raised for research and education at 24th annual golf outing

Over $300,000 raised for research and education at 24th annual golf outing

June 26th, 2017

News
Giving

Over 180 golfers took to the greens at Piping Rock Club at Cold Spring Harbor Laboratory’s 24th annual golf tournament....

Latest advances in malaria research in free eBook by Cold Spring Harbor Laboratory Press

Latest advances in malaria research in free eBook by Cold Spring Harbor Laboratory Press

June 26th, 2017

News
Institutional

J.C. Flowers Foundation grant gives practitioners in malaria-endemic areas access to a critical resource...

New statistical method finds shared ancestral gene variants involved in autism’s cause

New statistical method finds shared ancestral gene variants involved in autism’s cause

June 21st, 2017

News
Research

Researchers find children with autism are genetically more like other autistic children than their unaffected siblings....

CRISPR vs. climate change

CRISPR vs. climate change

June 15th, 2017

Feature
Research

This episode of Base Pairs looks at the issues climate change may bring to agriculture and how CRISPR can help overcome them....

How cool is science? Students use barcoded DNA to identify a weapon against antibiotic resistance

How cool is science? Students use barcoded DNA to identify a weapon against antibiotic resistance

June 14th, 2017

Blog
Education

Sometimes viruses cause harmful infections, but students in the DNA Learning Center’s Urban Barcode Research Program identified a new virus that could...

Open House brings 500+ new friends to Cold Spring Harbor Laboratory campus

Open House brings 500+ new friends to Cold Spring Harbor Laboratory campus

June 13th, 2017

News
Education Institutional

Cold Spring Harbor Laboratory (CSHL) welcomed 500+ new friends on June 10, 2017 to share the thrill of scientific discovery....

Detailed new ‘reference’ genome for maize shows the plant has deep resources for continued adaptation

Detailed new ‘reference’ genome for maize shows the plant has deep resources for continued adaptation

June 12th, 2017

News
Research

A new, much more detailed reference genome for maize, or corn, as it is called in the U.S., provides new insight into the crop....

Math teacher wins school popularity contest (again)

Math teacher wins school popularity contest (again)

June 7th, 2017

Blog
Education

Math isn’t exactly known as “everyone’s favorite subject,” yet Associate Professor Mickey Atwal has won the Watson School of Biological Science’s...

A protein that stem cells require could be a target in killing breast cancer cells

A protein that stem cells require could be a target in killing breast cancer cells

June 1st, 2017

News
Research

Cancer cells, like stem cells, have the ability to multiply indefinitely but epigenetic factor BPTF may be a shared weakness....

Hanging with Heroes and Friends Who Care raise over $17,000 to support Cold Spring Harbor Laboratory’s Breast Cancer Research

Hanging with Heroes and Friends Who Care raise over $17,000 to support Cold Spring Harbor Laboratory’s Breast Cancer Research

May 29th, 2017

News
Giving

On Saturday, April 22, 2017, 245 people attended the 4th annual Hanging with Heroes fundraiser held at Driftwood Camp in Melville. ...

Fine-tuning dosage of mutant genes unleashes long-trapped yield potential in tomato plants

Fine-tuning dosage of mutant genes unleashes long-trapped yield potential in tomato plants

May 18th, 2017

News
Research

Understanding gene interactions can enable breeders to break existing productivity barriers in agriculture....

Expert Explains: Is confidence measurable?

Expert Explains: Is confidence measurable?

May 16th, 2017

Blog
Research

Confidence is “not just a feeling,” according to neuroscientist Adam Kepecs. Finding the confidence-calculating circuitry in our brains has huge...

Redefining biologists, redefining genes

Redefining biologists, redefining genes

May 16th, 2017

Feature
Research

Drs. Molly Hammell and Thomas Gingeras talk about redefining what a biologist is and what genes are....

CSHL to lead international team developing next-generation organoid cancer research

CSHL to lead international team developing next-generation organoid cancer research

May 11th, 2017

News
Research

Cold Spring Harbor Laboratory (CSHL) has been awarded a research subcontract by Leidos Biomedical Research to lead a Cancer Model Development Center (CMDC) for pancreatic, breast, colorectal, lung, liver and other upper-gastrointestinal cancers....

Nobel laureate Dr. Carol Greider gives keynote at Cold Spring Harbor Laboratory graduation

Nobel laureate Dr. Carol Greider gives keynote at Cold Spring Harbor Laboratory graduation

May 8th, 2017

News
Education WSBS

Eight new Ph.D.s join 90 alumni who have earned a degree from the Watson School of Biological Sciences in the 18 years since its accreditation....

Newly discovered mutations impair key cell pathways in pancreatic cancer

Newly discovered mutations impair key cell pathways in pancreatic cancer

May 8th, 2017

News
Research

Researchers have found important new clues to the development of pancreatic cancer....

Pershing Square Sohn cancer research prize awarded to CSHL’s Dr. Mikala Egeblad

Pershing Square Sohn cancer research prize awarded to CSHL’s Dr. Mikala Egeblad

May 8th, 2017

News
Research

Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad, Ph.D., has been awarded the Pershing Square Sohn Prize....

CSHL’s Dr. Leemor Joshua-Tor is elected to The National Academy of Sciences

CSHL’s Dr. Leemor Joshua-Tor is elected to The National Academy of Sciences

May 2nd, 2017

News
Research

Professor Leemor Joshua-Tor has been elected to The National Academy of Sciences (NAS)....

Alexa DeAngelis didn’t see a place for herself in science, so she’s making one

Alexa DeAngelis didn’t see a place for herself in science, so she’s making one

April 28th, 2017

Blog
Education

For Alexa DeAngelis, who was recently awarded a Fulbright scholarship, combining a desire to help people with a passion for biochemistry means design...

Cold Spring Harbor Laboratory to boost sharing of global scientific research in collaboration with the Chan Zuckerberg Initiative

Cold Spring Harbor Laboratory to boost sharing of global scientific research in collaboration with the Chan Zuckerberg Initiative

April 26th, 2017

News
Institutional Research

To accelerate the pace of scientific discovery, the bioRxiv preprint service will advance free distribution of research manuscript drafts....

Everyday steps you can take for science

Everyday steps you can take for science

April 21st, 2017

Blog
Education

Effective advocacy for science is the culmination of many small steps...

Dark matter of the genome, part 2

Dark matter of the genome, part 2

April 15th, 2017

Feature
Research

This episode of Base Pairs deals with the myth of "junk DNA" and why scientists are interested in non-coding portions of the genome....

CSHL’s Dr. Leemor Joshua-Tor Elected to American Academy of Arts and Sciences

CSHL’s Dr. Leemor Joshua-Tor Elected to American Academy of Arts and Sciences

April 14th, 2017

News
Research

Professor Leemor Joshua-Tor is among 228 newly elected members of The American Academy of Arts and Sciences...

New research explains why even targeted therapies eventually fail in lung cancer

New research explains why even targeted therapies eventually fail in lung cancer

March 29th, 2017

News
Research

Dr. Sordella and her team propose a novel theory of how some cancers circumvent the killing power of targeted therapies....

Research suggests a possible role for a storm of ‘jumping genes’ in ALS

Research suggests a possible role for a storm of ‘jumping genes’ in ALS

March 27th, 2017

News
Research

New research demonstrates that some transposons are no longer effectively inhibited, resulting in a storm of jumping genes, leading to DNA damage....

What a real-life science test looks like

What a real-life science test looks like

March 24th, 2017

Blog
Research

By revealing evidence that contradicts the rationale for a new cancer drug, a pair of student scientists learns firsthand that when you do science...

Trinity College President Joins Board of Cold Spring Harbor Laboratory

Trinity College President Joins Board of Cold Spring Harbor Laboratory

March 21st, 2017

News
Institutional

Dr. Joanne Berger-Sweeney, president of Trinity College, was elected to the CSHL Board of Trustees....

Protein complex that takes first steps in human DNA replication dance is captured at high atomic resolution

Protein complex that takes first steps in human DNA replication dance is captured at high atomic resolution

March 16th, 2017

News
Research

Human ORC complex captured in action in x-ray crystallography and cryo-EM...

Dark matter of the genome, part 1

Dark matter of the genome, part 1

March 15th, 2017

Feature
Research

This episode of Base Pairs digs into "dark matter" a type of genetic information that could help scientists better understand diseases like...

Expert explains: Can we understand memories at the molecular level?

Expert explains: Can we understand memories at the molecular level?

March 13th, 2017

Blog
Research

Memories may seem intangible, but many scientists are working to figure out how they are physically stored in the brain. To achieve this, we’ll need ...

Dopamine neurons factor ambiguity into predictions that enable us to “win big and win often”

Dopamine neurons factor ambiguity into predictions that enable us to “win big and win often”

March 9th, 2017

News
Research

Researchers describe how dopamine-releasing neurons weigh the ambiguity of sensory information, indicating that neurons are highly sophisticated....

New art supplies for visualizing tiny machines in the brain

New art supplies for visualizing tiny machines in the brain

March 1st, 2017

Blog
Research

An unusual, but beautiful sight can be found among the figures of a recent scientific paper about some of the tiny machines in our brain: watercolor...

The Children’s Heart Foundation awards $50,000 to CSHL researcher

The Children’s Heart Foundation awards $50,000 to CSHL researcher

February 28th, 2017

News
Giving Institutional

The New York Chapter of The Children’s Heart Foundation (CHF) presented Dr. Michael Ronemus of Cold Spring Harbor Laboratory (CSHL) a $50,000 grant....

Glen Cove CARES donates $7,000 to breast cancer research at CSHL

Glen Cove CARES donates $7,000 to breast cancer research at CSHL

February 27th, 2017

News
Giving

Marilyn Abrams and Lorri Prince of Glen Cove CARES presented a $7,000 check to Dr. Mikala Egeblad, Professor at Cold Spring Harbor Laboratory to support her breast cancer research...

Discovery of distinct cell subtypes around tumors helps explain why pancreatic cancer is so hard to treat

Discovery of distinct cell subtypes around tumors helps explain why pancreatic cancer is so hard to treat

February 23rd, 2017

News
Research

Researchers finds that stroma,“wound”-like tissue that surrounds the tumors, helps explain why pancreatic cancer is so resistant to treatment....

Researchers identify ‘Achilles’ heel’ of PTEN that helps drive prostate cancer progression

Researchers identify ‘Achilles’ heel’ of PTEN that helps drive prostate cancer progression

February 13th, 2017

News
Research

Researchers at CSHL have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it....

CSHL statement regarding Executive Order on border security and immigration

CSHL statement regarding Executive Order on border security and immigration

February 1st, 2017

News
Institutional

CSHL statement regarding Executive Order on border security and immigration...

Molecules and a mission

Molecules and a mission

January 27th, 2017

Feature
Research

A special bonus episode of Base Pairs offering an explanation of why the name "Base Pairs" was chosen...

In mouse model of Rett syndrome, research reveals how adult learning is impaired in females

In mouse model of Rett syndrome, research reveals how adult learning is impaired in females

January 18th, 2017

News
Research

Researchers found that the failure of the Mecp2 gene, which leads to Rett syndrome, has biological consequences later in life....

Cancer research biobank formed by Northwell Health and Indivumed will enhance CSHL-Northwell alliance

Cancer research biobank formed by Northwell Health and Indivumed will enhance CSHL-Northwell alliance

January 17th, 2017

News
Institutional

Northwell Health and Indivumed collaborate to greatly expand cancer biobanking activities within Northwell Health to develop medical approaches....

Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments

Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments

January 12th, 2017

News
Research

Pre-malignant aneuploid cells grew more slowly and formed smaller tumors than comparable cells with normal chromosome number, CSHL researchers found....

CSHL joins NCI-designated cancer centers in endorsing updated HPV vaccination recommendations

CSHL joins NCI-designated cancer centers in endorsing updated HPV vaccination recommendations

January 11th, 2017

News
Institutional

Dr. Stillman and Dr. Tuveson joined with the leaders of other institutions nationwide in endorsing a statement regarding the HPV vaccine....

Plus-sized fly: a model to understand the mechanisms underlying human obesity

Plus-sized fly: a model to understand the mechanisms underlying human obesity

January 10th, 2017

News
Research

The fly sheds light on how the brain acts to signal “fullness” and the possibility of conferring resilience against the impact of high-fat diets...

Austin’s Purpose Raises $10,000 for Cold Spring Harbor Laboratory Neuroscience

Austin’s Purpose Raises $10,000 for Cold Spring Harbor Laboratory Neuroscience

January 4th, 2017

News
Giving

Austin’s Purpose presented CSHL Hiro Furukawa with a donation to continue NMDA research....

Cold Spring Harbor Laboratory Sarcoma Research Update

Cold Spring Harbor Laboratory Sarcoma Research Update

January 4th, 2017

News
Giving

Over the last two years, CSHL has applied its excellence in basic research and innovative technology development to understanding the rare but intractable sarcoma cancers. ...

FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL

FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL

December 24th, 2016

News
Research

Nusinersen (Spinraza) will be used to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA)....

Join Glen Cove CARES for their 20th Anniversary

Join Glen Cove CARES for their 20th Anniversary

December 20th, 2016

News
Giving Institutional

Join Glen Cove CARES for their 20th Anniversary celebration....

MWCABC donates $65,000 to breast cancer research at CSHL

MWCABC donates $65,000 to breast cancer research at CSHL

December 14th, 2016

News
Giving

The Manhasset Women's Coalition Against Breast Cancer presented a check to support Dr. Camila dos Santos' breast cancer research....

The brain atlas

The brain atlas

December 14th, 2016

Feature
Research

This episode of BasePairs looks at the problems of neuropsychiatric drug discovery, and the method by which they may soon be resolved....

Cold Spring Harbor HS Football Player donates CSHL’s breast cancer research

Cold Spring Harbor HS Football Player donates CSHL’s breast cancer research

December 13th, 2016

News
Giving

Eli Gordon, kicker for the Cold Spring Harbor football team, presented a check today for $1,000.00 for breast cancer research....

Dr. Robert Maki joins Northwell Health Cancer Institute and CSHL to direct Center for New Cancer Therapies

Dr. Robert Maki joins Northwell Health Cancer Institute and CSHL to direct Center for New Cancer Therapies

December 12th, 2016

News
Research

Dr. Robert G. Maki an internationally-renowned sarcoma cancer physician and researcher, joins the leadership of the Northwell Health Cancer Institute....

For Alan Alda, science communication is a state of mind

For Alan Alda, science communication is a state of mind

December 9th, 2016

Blog
Institutional

An interview with actor and science communication advocate Alan Alda about his work at the Alda Center for Communicating Science....

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

December 9th, 2016

News
Research

Truncated p53 proteins, presumed unimportant, now point to new drug targets for some of "the hardest cancers"...

Annual Appeal letter

Annual Appeal letter

December 7th, 2016

News
Giving

When you give to Cold Spring Harbor Laboratory, you are making an investment in the careers of young scientists....

Gene editing yields tomatoes that flower and ripen weeks earlier

Gene editing yields tomatoes that flower and ripen weeks earlier

December 5th, 2016

News
Research

Researchers use CRISPR to expand the geographical range of important food crops....

11th Double Helix Medals raises $4.3 million for biomedical research and education at Cold Spring Harbor Laboratory

11th Double Helix Medals raises $4.3 million for biomedical research and education at Cold Spring Harbor Laboratory

December 2nd, 2016

News
Giving Institutional

More than $4.3 million was raised last night at Cold Spring Harbor Laboratory’s 11th Double Helix Medals dinner, honoring Alan Alda and P. Roy Vagelos...

One experiment: A drug for SMA visibly repairs defective cells

One experiment: A drug for SMA visibly repairs defective cells

December 1st, 2016

Feature
Research

Professor Adrian Krainer develops a treatment for spinal muscular atrophy, the leading genetic cause of infant death....

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

December 1st, 2016

News
Research

Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia....

Dr. David Tuveson named Director, NCI-Designated Cancer Center at Cold Spring Harbor Laboratory

Dr. David Tuveson named Director, NCI-Designated Cancer Center at Cold Spring Harbor Laboratory

November 29th, 2016

News
Institutional

Dr. David Tuveson, M.D., Ph.D., succeeds Dr. Bruce Stillman as Director of the Cold Spring Harbor Laboratory (CSHL) Cancer Center....

When antioxidants are pro-cancer

When antioxidants are pro-cancer

November 15th, 2016

Feature
Research

For Pancreatic Cancer Awareness Month, Base Pairs looks at the science of antioxidants and cancer....

No (real) moustache required to join the “Movember” party

No (real) moustache required to join the “Movember” party

November 15th, 2016

Blog
Research

Members of Trotman don fake moustaches in order to raise money for prostate cancer research during Movember. ...

Focus on quiescent cells brings to light the essential role of RNA interference in transcription control

Focus on quiescent cells brings to light the essential role of RNA interference in transcription control

November 9th, 2016

News
Research

RNAi and other epigenetic processes induce changes in where and when specific genes are expressed without altering their genetic code....

Pancreas and colon tumors reprogram the liver, causing wasting and short-circuiting body’s immune response

Pancreas and colon tumors reprogram the liver, causing wasting and short-circuiting body’s immune response

November 8th, 2016

News
Research

Research reveals a mechanism that causes wasting in cancer and tests a way to reverse it....

Gene network controls how many flowers and fruits plants will produce during critical growth window

Gene network controls how many flowers and fruits plants will produce during critical growth window

November 7th, 2016

News
Research

Researchers use RNA sequencing to identify a network of genes that work together to determine the duration of a critical window for growth....

The Claire Friedlander Family Foundation Donates $200,000 for New Sequencer

The Claire Friedlander Family Foundation Donates $200,000 for New Sequencer

October 28th, 2016

News
Giving

Claire Friedlander Family Foundation donated $200,000 for new equipment at the Woodbury Genome Center....

The “secret” science center where openness is everything

The “secret” science center where openness is everything

October 27th, 2016

Blog
Banbury Research

Lyme disease researcher Steven Schutzer talks about the important meetings held in the Banbury Center....

A theoretical physicist’s approach to breast cancer

A theoretical physicist’s approach to breast cancer

October 21st, 2016

Blog
Research

Associate Professor Mickey Atwal explains how exploring numbers and patterns could lead to a new cancer treatment strategy....

Our most common infection-fighting white blood cells can be hijacked to support cancer spread

Our most common infection-fighting white blood cells can be hijacked to support cancer spread

October 19th, 2016

News
Research

Neutrophils, the most common type of white blood cell, can be taken over by cancer cells and used as an aid in metastasis....

Masthead Cove Yacht Club raises over $7000 for CSHL research at annual race

Masthead Cove Yacht Club raises over $7000 for CSHL research at annual race

October 19th, 2016

News
Giving Institutional

Members of the Masthead Cove Yacht Club (MCYC) raised $7,007 from their annual Masthead Race on August 14, 2016....

“Sink or swim”

“Sink or swim”

October 15th, 2016

Feature
Research

This episode of Base Pairs follows Professor Adrian Krainer and his experience as the first CSHL fellow....

Expert explains: What’s the connection between antioxidants and cancer?

Expert explains: What’s the connection between antioxidants and cancer?

October 14th, 2016

Blog
Research

David Tuveson discusses the relationship between antioxidants and cancer, and how the former doesn't necessarily prevent the latter....

Non-coding portions of genome are found to play role in cancer

Non-coding portions of genome are found to play role in cancer

September 27th, 2016

News
Research

CSHL scientists test an antisense method of targeting long noncoding RNAs overexpressed in breast cancers....

Three words I heard from my pediatric oncologist that still haunt me

Three words I heard from my pediatric oncologist that still haunt me

September 26th, 2016

Blog
Research

Kayla Funk, a childhood cancer survivor, on her experiences with pediatric cancer and the push for more funding for research....

Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly

Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly

September 21st, 2016

News
Research

Researchers have uncovered a neural circuit that processes evaluations and have succeeded in identifying its sources....

Innovative tools will shed clarifying light on inhibitory neurons

Innovative tools will shed clarifying light on inhibitory neurons

September 21st, 2016

News
Research

Researchers at Cold Spring Harbor Laboratory created a set of tools that combine genetic markers and virus particles to target GABA cell types....

15th Women’s Partnership for Science luncheon features Lasker Prize winner Evelyn Witkin

15th Women’s Partnership for Science luncheon features Lasker Prize winner Evelyn Witkin

September 21st, 2016

News
Institutional

15th Annual Women's Partnership raises over $200,000 for disease research at Cold Spring Harbor Laboratory...

LI2Day Walk supports Cold Spring Harbor Laboratory’s breast cancer research

LI2Day Walk supports Cold Spring Harbor Laboratory’s breast cancer research

September 19th, 2016

News
Giving

LI2Day donated $2,000 to CSHL, having donated nearly $300,000 to support breast cancer research at the CSHL since 2004....

Stand Up for Suzanne donates $10,000 to Cold Spring Harbor Laboratory

Stand Up for Suzanne donates $10,000 to Cold Spring Harbor Laboratory

September 19th, 2016

News
Giving

Regina Caliendo and Doris Jelinek presented a $10,000 check to Dr. Sarah Diermeier for breast cancer research....

Why calling childhood cancers “rare” is missing the point

Why calling childhood cancers “rare” is missing the point

September 19th, 2016

Blog
Research

Associate Professor Christopher Vakoc on why calling pediatric cancers "rare" actually hurts their chances of being studied....

The people problem

The people problem

September 15th, 2016

Feature
Research

This episode of Base Pairs looks at the rising population, plant biology, and the future of food....

How a cold-causing virus and inexplicable experiments helped revolutionize thinking about the genome

How a cold-causing virus and inexplicable experiments helped revolutionize thinking about the genome

September 6th, 2016

Blog
Research

Nobel laureate Richard Roberts discusses the importance of RNA splicing and how scientists can learn from "failed" experiments....

Preprint server bioRxiv receives additional major funding

Preprint server bioRxiv receives additional major funding

August 26th, 2016

News
Institutional

Increased support will fuel continued growth and technical development of the increasingly prominent biomedical preprint service....

Painting with microbes brings an unseen world into public view

Painting with microbes brings an unseen world into public view

August 24th, 2016

Blog
Education

We live in exciting times. Until recently, the microscope was the only way for scientists to take a closer look at microorganisms. ...

Revolutionary method to map the brain at single-neuron resolution is successfully demonstrated

Revolutionary method to map the brain at single-neuron resolution is successfully demonstrated

August 19th, 2016

News
Research

MAPseq can trace the long-range projections of large numbers of individual neurons from a specific region to wherever they lead in the brain....

Non-modern family

Non-modern family

August 15th, 2016

Feature
Education Research

This episode on Base Pairs explores how genetic information to better understand human history....

Candidate drug for spinal muscular atrophy, with roots in CSHL research, passes major hurdle

Candidate drug for spinal muscular atrophy, with roots in CSHL research, passes major hurdle

August 4th, 2016

News
Research

Biotechnology firms Biogen and Ionis Pharmaceuticals cut short a phase-3 clinical trial for the investigational drug nusinersen as it met endpoint....

Riding out of the shadows of ALS, toward better treatments

Riding out of the shadows of ALS, toward better treatments

August 1st, 2016

Blog
Research

Graduate student Lisa Krug discusses her research and personal connection to ALS, and Ride for Life, a not-for-profit organization for ALS research....

Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidants

Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidants

July 28th, 2016

News
Research

Researchers demonstrate that in the specific context of pancreatic cells leading to cancer, raisin antioxidant levels should not be raised....

To divide or not: a cellular feedback loop that enables new cells to make a fateful decision

To divide or not: a cellular feedback loop that enables new cells to make a fateful decision

July 21st, 2016

News
Research

Team explains a key mechanism to prevent aberrant cell proliferation...

Science is hard, and these high schoolers are fine with that

Science is hard, and these high schoolers are fine with that

July 20th, 2016

Blog
Education

With DNA barcoding, high school seniors Sydney Lyncook and Tanjil Uddin realized that they had the power to show whether the manufacturers of ...

Corn controversy

Corn controversy

July 15th, 2016

Feature
Research

This episode of Base Pairs covers the contentious genetics and history of America’s corn production....

Discovery of new ovarian cancer signaling hub points to target for limiting metastasis

Discovery of new ovarian cancer signaling hub points to target for limiting metastasis

July 10th, 2016

News
Research

A team of researchers at Cold Spring Harbor Laboratory discovers new insights into signaling events that underlie metastasis in ovarian cancer cells....

Academic-industry collaboration generates elegant way of pinpointing how a new drug exerts beneficial effects

Academic-industry collaboration generates elegant way of pinpointing how a new drug exerts beneficial effects

July 5th, 2016

News
Research

Researchers identify a new drug target in leukemia and creation of a candidate drug that hits the target....

One experiment: How the breast “remembers” a first pregnancy

One experiment: How the breast “remembers” a first pregnancy

July 2nd, 2016

Feature
Research

Professor Greg Hannon and his team, including Assistant Professor Camila dos Santos, learn more about breast cells and tissue....

Basic research needs your support

Basic research needs your support

June 30th, 2016

News
Research

CSHL partners with Research!America to find out where political candidates stand on support for basic research....

Cancer researcher Camila dos Santos of CSHL is named a Rita Allen Foundation Scholar

Cancer researcher Camila dos Santos of CSHL is named a Rita Allen Foundation Scholar

June 29th, 2016

News
Institutional

Assistant Professor Camila dos Santos of Cold Spring Harbor Laboratory (CSHL) has been selected as one of seven 2016 Rita Allen Foundation Scholars. ...

“Amazing protein diversity” is discovered in the maize plant

“Amazing protein diversity” is discovered in the maize plant

June 24th, 2016

News
Research

The genome of the corn plant “is a lot more exciting” than scientists have previously believed....

From phages to faces

From phages to faces

June 15th, 2016

Feature
Research

In the pilot episode of Base Pairs, two stories of DNA research that show how far the field has come...

Pew Trusts name CSHL’s Daniel Rodríguez-Leal a Latin American Fellow in Biomedical Sciences

Pew Trusts name CSHL’s Daniel Rodríguez-Leal a Latin American Fellow in Biomedical Sciences

June 9th, 2016

News
Institutional

Daniel Rodríguez-Leal, Ph.D., a postdoctoral investigator was selected for the Pew Latin American Fellows in the Biomedical Sciences...

Don’t fall into the culture gap between science and business

Don’t fall into the culture gap between science and business

June 8th, 2016

Blog
Education

Key takeaways from the lecture “Bench to Bioscience Enterprise” which talks about the connections between business and science....

CSHL receives its 15th 4-star rating from Charity Navigator

CSHL receives its 15th 4-star rating from Charity Navigator

June 6th, 2016

News
Giving

Cold Spring Harbor Laboratory has received Charity Navigator’s highest possible 4-star rating for the 15th time...

The WTFC Foundation supports breast cancer research at CSHL

The WTFC Foundation supports breast cancer research at CSHL

June 6th, 2016

News
Giving

The WTFC Foundation held its 10th Annual "The Breast of Everything" fundraiser, raising over $40,000 to support breast cancer research...

DIY neuroscience opens up a universe of possibilities in Transylvania

DIY neuroscience opens up a universe of possibilities in Transylvania

June 1st, 2016

Blog
Education

Do-it-yourself (“DIY”) science evokes images of amateur scientists tinkering with test tubes in garages on the weekends. So, at first, the picture of ...

Pershing Square Sohn Cancer Research Alliance awards prize to CSHL’s  Christopher Vakoc

Pershing Square Sohn Cancer Research Alliance awards prize to CSHL’s Christopher Vakoc

May 27th, 2016

News
Institutional

Associate Professor Christopher Vakoc of Cold Spring Harbor Laboratory is among seven winners of the third annual Pershing Square Sohn Prize...

ALS Ride for Life comes to Cold Spring Harbor Laboratory

ALS Ride for Life comes to Cold Spring Harbor Laboratory

May 23rd, 2016

News
Giving Institutional

CSHL gathered to welcome Chris Pendergast and his ALS Ride for Life team to campus on Monday, May 16....

Discovery of new stem cell pathway indicates route to much higher yields in maize, staple crops

Discovery of new stem cell pathway indicates route to much higher yields in maize, staple crops

May 16th, 2016

News
Research

Researchers discover a new regulatory pathway that channels signals emanating from a plant's extremities to the stem cell niche....

Our brain uses statistics to calculate confidence, make decisions

Our brain uses statistics to calculate confidence, make decisions

May 4th, 2016

News
Research

The brain produces feelings of confidence that inform decisions the same way statistics pulls patterns out of noisy data....

Alumnus Josh Sanders makes neuroscience research tools open and affordable

Alumnus Josh Sanders makes neuroscience research tools open and affordable

May 2nd, 2016

News
Education WSBS

Josh Sanders developed a series of tools for neuroscience research that filled major needs in the field....

Cold Spring Harbor Laboratory confers 90th Ph.D.

Cold Spring Harbor Laboratory confers 90th Ph.D.

May 2nd, 2016

News
Education WSBS

On May 1, proud friends and family mingled with distinguished scientists at the 13th commencement ceremony of the Watson School of Biological Sciences...

WSBS Teaching Award 2016 for Mickey Atwal

WSBS Teaching Award 2016 for Mickey Atwal

May 2nd, 2016

News
Education WSBS

Mickey Atwal is the third two-time winner of the Winship Herr Award for Excellence and Creativity in Teaching....

First structural views of the NMDA receptor in action will aid drug development

First structural views of the NMDA receptor in action will aid drug development

May 2nd, 2016

News
Research

Structural biologists obtained snapshots of the activation of an important type of brain-cell receptor....

Graduation 2016

Graduation 2016

April 29th, 2016

News
WSBS

Watson School awards seven Ph.D. degrees, to students who studied topics ranging from single-cell sequence data analysis to acute myeloid leukemia....

Expert explains: Why is autism more common in boys?

Expert explains: Why is autism more common in boys?

April 29th, 2016

Blog
Research

Ivan Iossifov talks about some of the reasons why autism disproportionately effects boys on a genetic level....

Cold Spring Harbor Laboratory launches $75 million Center for Therapeutics Research to develop new drugs

Cold Spring Harbor Laboratory launches $75 million Center for Therapeutics Research to develop new drugs

April 22nd, 2016

News
Institutional

CSHL announced the Center for Therapeutics Research project, applying biomedical expertise towards advancing therapeutics for genetic diseases....

Expert explains: What do autism “risk genes” do?

Expert explains: What do autism “risk genes” do?

April 21st, 2016

Blog
Research

A discussion with Ivan Iossifov with what exactly the term "risk genes" means and what they do....

Adrian Krainer of Cold Spring Harbor Laboratory elected to American Academy of Arts and Sciences

Adrian Krainer of Cold Spring Harbor Laboratory elected to American Academy of Arts and Sciences

April 20th, 2016

News
Institutional

Adrian Krainer was elected to the American Academy of Arts and Sciences....

Executive in Residence to mentor scientific entrepreneurs at Cold Spring Harbor Laboratory

Executive in Residence to mentor scientific entrepreneurs at Cold Spring Harbor Laboratory

April 15th, 2016

News
Institutional

Andrew Whiteley joined the Cold Spring Harbor Laboratory Office of Technology Transfer as the first Executive in Residence....

Expert explains: How many autism “risk genes” have scientists found?

Expert explains: How many autism “risk genes” have scientists found?

April 14th, 2016

Blog
Research

A look at the research which points to the different genes potentially at the root of autism....

CSHL scientists Bo Li and Je Lee win HFSP Research Grant awards

CSHL scientists Bo Li and Je Lee win HFSP Research Grant awards

April 12th, 2016

News
Research

Associate Professor Bo Li and Assistant Professor Je Lee, are among 25 teams that have won Human Frontier Science Program Research Program Grants...

Expert explains: Where does autism come from when it doesn’t run in the family?

Expert explains: Where does autism come from when it doesn’t run in the family?

April 7th, 2016

Blog
Research

Associate Professor Ivan Iossifov discusses how parents who are not autistic can pass autism onto their children through their genes....

U.S. Patent Office denies all 4 petitions filed by Benitec Biopharma against CSHL’s shRNA patents

U.S. Patent Office denies all 4 petitions filed by Benitec Biopharma against CSHL’s shRNA patents

April 6th, 2016

News
Institutional

U.S. Patent & Trademark Office has denied all 4 petitions filed by Benitec Biopharma Ltd seeking to invalidate CSHL's patents directed to shRNA....

Imaging hundreds of neurons using ultrafast lasers hints at how brains make decisions

Imaging hundreds of neurons using ultrafast lasers hints at how brains make decisions

March 15th, 2016

Blog
Research

Neuroscientist Matt Kaufman uses brief, ultrafast laser pulses to understand how the brain makes sensory-guided decisions....

If you thought all neuroscientists work with neurons, you’re wrong

If you thought all neuroscientists work with neurons, you’re wrong

February 25th, 2016

Blog
Research

Neuroscientists talk about the importance of the intersections between theory and experiment, and how it has shaped their work....

Joni Gladowsky Foundation to hold breast cancer fundraiser for CSHL

Joni Gladowsky Foundation to hold breast cancer fundraiser for CSHL

February 25th, 2016

News
Giving

The Joni Gladowsky Foundation holds its annual Winter Classic Hockey Tournament....

Student Lisa Krug quells the transposon storm of ALS

Student Lisa Krug quells the transposon storm of ALS

February 22nd, 2016

News
WSBS

Lisa Krug defended her Ph.D. thesis, in which she studied the molecular basis of ALS in a model organism: the fruit fly Drosophila melanogaster....

Neanderthals mated with modern humans much earlier than previously thought, study finds

Neanderthals mated with modern humans much earlier than previously thought, study finds

February 12th, 2016

News
Research

Using several different methods of DNA analysis, an international research team has found what they consider to be strong evidence of interbreeding....

Ancient gene network helps plants adapt to their environments

Ancient gene network helps plants adapt to their environments

February 9th, 2016

News
Research

Reseachers discovered the purpose of a tool present in both mosses and flowering plants, organisms whose common ancestor dates back 450 million years....

How healthy cells might help cancer survive

How healthy cells might help cancer survive

February 4th, 2016

Blog
Research

A story on Mikala Egeblad's breast cancer research and the importance of the tumor microenvironment....

Stand Up for Suzanne’s annual luncheon will support breast cancer research at CSHL

Stand Up for Suzanne’s annual luncheon will support breast cancer research at CSHL

February 3rd, 2016

News
Giving

Stand Up for Suzanne, a Long Island-based group founded to support cutting edge research at Cold Spring Harbor Laboratory held their annual luncheon...

A consortium to map the brain is launched

A consortium to map the brain is launched

February 2nd, 2016

News
Research

The Wyss Institute for Biologically Inspired Engineering announced a cross-institutional consortium to map the brain's neural circuits....

Christina Renna Foundation Raises $35,000 for pediatric cancer research at CSHL

Christina Renna Foundation Raises $35,000 for pediatric cancer research at CSHL

January 29th, 2016

News
Giving Institutional

The Christina Renna Foundation presented $35,000 to Cold Spring Harbor Laboratory (CSHL) at its 9th annual Angel's Wish Gala....

CSHL joins nation’s cancer centers in endorsement of HPV vaccination for cancer prevention

CSHL joins nation’s cancer centers in endorsement of HPV vaccination for cancer prevention

January 27th, 2016

News
Institutional

Cold Spring Harbor Laboratory joined 68 other top cancer centers in issuing a statement urging increased HPV vaccination for the prevention of cancer...

Partners Profile: High School Senior Tamanna Bhatia on becoming a scientist

Partners Profile: High School Senior Tamanna Bhatia on becoming a scientist

January 26th, 2016

Blog
Education

An interview with Partners for the Future participant Tamanna Bhatia and her work in Alea Mill's lab studying cancer cells....

The iPlant Collaborative is now called CyVerse

The iPlant Collaborative is now called CyVerse

January 15th, 2016

News
Institutional

The enhanced NSF project will now provide data management and computation across scientific disciplines...

bioRxiv preprints can now be submitted directly to leading research journals

bioRxiv preprints can now be submitted directly to leading research journals

January 15th, 2016

News
Research

Cold Spring Harbor Laboratory announced that authors of manuscripts posted on its preprint server can now submit papers directly to leading journals....

A new way to fear: Lady lab rats raise important questions for behavioral research

A new way to fear: Lady lab rats raise important questions for behavioral research

January 12th, 2016

Blog
Research

A discussion of female rats as research subjects and how their hormonal cycle comes into play....

Solving the problem with penicillin

Solving the problem with penicillin

January 11th, 2016

Blog
History Institutional

In celebration of scientist Milislav Demerec, a look at how he discovered a strain of Penicillium that more effectively produced pencillin....

Clark Gillies Foundation gives $50,000 for sarcoma research at CSHL

Clark Gillies Foundation gives $50,000 for sarcoma research at CSHL

December 30th, 2015

News
Giving

The Clark Gillies Foundation presented $50,000 to Cold Spring Harbor Laboratory (CSHL) in support of the Sarcoma Research Project...

Unusual drug target and drug generate exciting preclinical results in mouse models of metastatic breast cancer

Unusual drug target and drug generate exciting preclinical results in mouse models of metastatic breast cancer

December 22nd, 2015

News
Research

Researchers publish preclinical data suggesting the promise of a novel drug directed against a novel target n malignant mammary tumors....

5th Graders spend a day as young scientists

5th Graders spend a day as young scientists

December 16th, 2015

Blog
Education

Students from the West Side Elementary School learn about the history and workings of Cold Spring Harbor Laboratory....

New method prevents cells from prematurely halting protein production in certain genetic illnesses

New method prevents cells from prematurely halting protein production in certain genetic illnesses

December 14th, 2015

News
Research

Research team succeeds in paradoxically inhibiting a process cells have evolved to prevent imperfect proteins from being synthesized...

Saving our food supply with alumna Michelle Cilia

Saving our food supply with alumna Michelle Cilia

December 11th, 2015

News
WSBS

Dr. Michelle Cilia has made it her mission to understand the bacteria and viruses that strike plants—and how to stop them...

DNA Justice—How the courtroom can learn from science

DNA Justice—How the courtroom can learn from science

December 7th, 2015

Blog
History

The case of Marvin Lamont Anderson, who was exonerated through the use of DNA evidence....

Discovery of a new X-linked intellectual disability syndrome is aided by web communication tools

Discovery of a new X-linked intellectual disability syndrome is aided by web communication tools

December 3rd, 2015

News
Research

A geneticist uses social media and online tools to help confirm, document and describe in precise clinical detail a new genetic syndrome in young ...

First direct evidence for synaptic plasticity in fruit fly brain

First direct evidence for synaptic plasticity in fruit fly brain

December 2nd, 2015

News
Research

Researchers have for the first time observed direct evidence of synaptic plasticity in fruit flies while they learn....

CSHL neuroscientist Anthony Zador is named a “Top 100 Global Thinker” of 2015

CSHL neuroscientist Anthony Zador is named a “Top 100 Global Thinker” of 2015

December 1st, 2015

News
Institutional

Anthony Zador was selected by the editors of the prestigious journal Foreign Policy as one of the Top 100 Leading Global Thinkers of 2015....

Unassuming “Swiss Army knife”-like protein proves lynchpin in a new cancer drug’s therapeutic action

Unassuming “Swiss Army knife”-like protein proves lynchpin in a new cancer drug’s therapeutic action

November 30th, 2015

News
Research

Researchers report a surprising mechanism through which an important new candidate drug against leukemia exerts its therapeutic effect....

High School students support pancreatic cancer research in a big way

High School students support pancreatic cancer research in a big way

November 25th, 2015

Blog
Research

Local high school students raise over $3,500 for pancreatic cancer research during the Long Island Pancreatic Cancer Research Walk....

Masthead Cove Yacht Club raises over $7000 for CSHL cancer research at annual race

Masthead Cove Yacht Club raises over $7000 for CSHL cancer research at annual race

November 25th, 2015

News
Giving Institutional

Members of the Masthead Cove Yacht Club (MCYC) raised $7,124 from their annual Masthead Race....

Movember: Fighting for health in the Lab and the gym

Movember: Fighting for health in the Lab and the gym

November 20th, 2015

Blog
Research

Dawid Nowak discusses the difficulties and challenges involved in understanding pancreatic cancer....

Regeneron’s Dr. George D. Yancopoulos Elected to Cold Spring Harbor Laboratory Board of Trustees

Regeneron’s Dr. George D. Yancopoulos Elected to Cold Spring Harbor Laboratory Board of Trustees

November 20th, 2015


Institutional

Cold Spring Harbor Laboratory announced the election of George D. Yancopoulos, M.D., Ph.D to its Board of Trustees....

Addition of sugars plays a key developmental role in distantly related plants

Addition of sugars plays a key developmental role in distantly related plants

November 19th, 2015

News
Research

Researchers found deleting the genes for enzymes in two plants widely separated in evolutionary time resulted in similar defects....

Breast cancer survivors show Camila dos Santos what’s important about her research

Breast cancer survivors show Camila dos Santos what’s important about her research

November 17th, 2015

Blog
Research

Camila dos Santos talks about what she has learned by talking with breast cancer survivors....

10th Double Helix Medals Dinner raises record $4.5 million for biomedical research at Cold Spring Harbor Laboratory

10th Double Helix Medals Dinner raises record $4.5 million for biomedical research at Cold Spring Harbor Laboratory

November 10th, 2015

News
Giving Institutional

The 10th Double Helix Medals dinner honored Katie Couric, Anne Wojcicki and David Botstein, champions of research to benefit mankind....

Student wins 1st Breakthrough Junior Challenge prize and his school gets a new state-of-the-art science lab designed by CSHL

Student wins 1st Breakthrough Junior Challenge prize and his school gets a new state-of-the-art science lab designed by CSHL

November 9th, 2015

News
Education

High school senior Ryan Chester was awarded the first-ever Breakthrough Junior Challenge prize....

Finding huge promise in a single cell with student Robert Aboukhalil

Finding huge promise in a single cell with student Robert Aboukhalil

November 2nd, 2015

News
WSBS

Robert Aboukhalil use his skills as a computational biologist to make single-cell genomic data easy for scientists and clinicians to access and use....

Breaking down breast cancer at CSHL

Breaking down breast cancer at CSHL

October 30th, 2015

Blog
Research

A look at how several researchers at CSHL contribute to the field of breast cancer research....

Who (else) was at Banbury in 1989 setting the stage for the Human Genome Project?

Who (else) was at Banbury in 1989 setting the stage for the Human Genome Project?

October 27th, 2015

Blog
Education History

A historical look back at the 1989 meeting at the Banbury Center which sparked the idea of the Human Genome Project....

Long Island man continues the fight against breast cancer in memory of his fiancé

Long Island man continues the fight against breast cancer in memory of his fiancé

October 20th, 2015

News
Giving

Michael Maringo established the Carissa Maringo Fund to support breast cancer research at Cold Spring Harbor Laboratory...

Rhabdomyosarcoma (RMS) research bolstered by $50,000 gift from Friends of TJ

Rhabdomyosarcoma (RMS) research bolstered by $50,000 gift from Friends of TJ

October 20th, 2015

News
Giving Institutional

The Friends of TJ Foundation presented a check for $50,000 to CSHL Associate Professor Chris Vakoc...

Ride For Life gives $300,000 for ALS research at Cold Spring Harbor Laboratory (CSHL)

Ride For Life gives $300,000 for ALS research at Cold Spring Harbor Laboratory (CSHL)

October 20th, 2015

News
Giving Institutional

ALS Ride For Life this month presented $300,000 to CSHL Assistant Professor Molly Hammell and Associate Professor Josh Dubnau...

Introducing the mighty Panoramix – defender of genomes!

Introducing the mighty Panoramix – defender of genomes!

October 15th, 2015

News
Research

Scientists have identified a protein the Piwi system uses to guide a cell's gene-silencing machinery to the right spots in the genome....

Breast Cancer Awareness Month: Mary-Claire King’s trailblazing research

Breast Cancer Awareness Month: Mary-Claire King’s trailblazing research

October 8th, 2015

Blog
Research

A look at the career of Mary-Claire King a geneticist who worked on the causes of breast cancer....

Approach or buzz off: brain cells in fruit fly hold secret to individual odor preferences

Approach or buzz off: brain cells in fruit fly hold secret to individual odor preferences

October 6th, 2015

News
Research

Scientists have discovered the point at which incoming sensory information begins to transform into a neural signal that instructs a fly's response....

CSHL Fellow wins 2015 NIH Early Independence Award for cancer research

CSHL Fellow wins 2015 NIH Early Independence Award for cancer research

October 6th, 2015

News
Research

CSHL Lab Fellow Jason Sheltzer won the 2015 Early Independence Award from the National Institutes of Health High Risk, High Reward Research Program...

The Human Genome Project opened a new era of science

The Human Genome Project opened a new era of science

October 2nd, 2015

Blog
Education History

A look back at the start of the Human Genome Project and CSHL's James Watson's role in it....

Research connects specific variations in RNA splicing with breast cancer causation

Research connects specific variations in RNA splicing with breast cancer causation

October 1st, 2015

News
Research

Researchers have identified cellular changes that may play a role in converting normal breast cells into tumors....

14th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory

14th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory

September 30th, 2015

News
Giving Institutional

Cold Spring Harbor Laboratory (CSHL) held the 14th annual Women's Partnership for Science luncheon....

Genetic analysis supports prediction that spontaneous rare mutations cause half of autism

Genetic analysis supports prediction that spontaneous rare mutations cause half of autism

September 22nd, 2015


Research

Scientists find evidence suggesting that devastating “ultra-rare” mutations play a causal role in roughly half of all autism spectrum disorders....

Scientists sequence genome of worm that can regrow body parts, seek stem cell insights

Scientists sequence genome of worm that can regrow body parts, seek stem cell insights

September 21st, 2015

News
Research

Worm’s genome could lead to better understanding of its regenerative prowess and advance stem cell biology....

Research bench to writing desk with alum Darren Burgess

Research bench to writing desk with alum Darren Burgess

September 17th, 2015

News
WSBS

A look at the career of an editor at a prestigious scientific journal....

What’s behind million-dollar crop failures in oil palm? Would you believe bad karma?

What’s behind million-dollar crop failures in oil palm? Would you believe bad karma?

September 9th, 2015


Research

A way to prevent damaged plantlets from being grown, to boost yield and reduce tropical land pressure....

Dr. Evelyn Witkin, ‘golden age’ Cold Spring Harbor geneticist, wins Lasker at age 94

Dr. Evelyn Witkin, ‘golden age’ Cold Spring Harbor geneticist, wins Lasker at age 94

September 8th, 2015

News
Institutional

Dr. Evelyn Witkin was honored at age 94 with a Lasker Award for achievement in Basic Science...

Mathematical ‘Gingko trees’ reveal mutations in single cells that characterize diseases

Mathematical ‘Gingko trees’ reveal mutations in single cells that characterize diseases

September 4th, 2015

News
Research

Online app could help clinicians choose the best treatments by comparing genetic fingerprints of individual cells...

Scientific inspiration with third-year student Annabel Romero Hernandez

Scientific inspiration with third-year student Annabel Romero Hernandez

September 1st, 2015

News
WSBS

Graduate student Annabel Romero Hernandez spent 244 days portraying the world around her on a very small scale....

Stand Up for Suzanne to hold fundraiser in support of breast cancer research at CSHL

Stand Up for Suzanne to hold fundraiser in support of breast cancer research at CSHL

September 1st, 2015

News
Giving

Stand Up for Suzanne to hold fundraiser in support of breast cancer research at CSHL...

12th annual LI2DAY Walk raises over $400,000

12th annual LI2DAY Walk raises over $400,000

September 1st, 2015

News
Institutional

The $19,000 donation received by CSHL will support breast cancer research in the laboratory of Professor Alea Mills....

CSHL’s 22nd annual golf tournament raises $230,000 for research and education

CSHL’s 22nd annual golf tournament raises $230,000 for research and education

August 27th, 2015

News
Giving

184 golfers took to the greens at Piping Rock Club for Cold Spring Harbor Laboratory's 22nd annual golf tournament...

Surprised? Cholinergic neurons send brain-wide broadcasts enabling us to learn from the unexpected

Surprised? Cholinergic neurons send brain-wide broadcasts enabling us to learn from the unexpected

August 25th, 2015

News
Research

Researchers find dedicated neurons that rapidly informing multiple subregions in the brain of any surprising rewards or punishments....

Matriculation 2015

Matriculation 2015

August 17th, 2015

News
WSBS

August 17, 2015, marks matriculation at the Watson School....

Continuing Professional Education course to be held at CSHL on 10/6/15

Continuing Professional Education course to be held at CSHL on 10/6/15

August 12th, 2015

News
Giving

2 credit continuing education class for accountants on Estate Planning will be held at Cold Spring Harbor Laboratory on 10/6/15....

Swim Across America fundraiser supports lung cancer research at CSHL

Swim Across America fundraiser supports lung cancer research at CSHL

August 12th, 2015

News
Giving

Swim Across America held its annual "Cove to Sound" swim at Morgan's Park in Glen Cove, NY on August 8, 2015...

Third-year student Abram Handly Santana explores the pancreatic tumor microenvironment

Third-year student Abram Handly Santana explores the pancreatic tumor microenvironment

August 1st, 2015

News
WSBS

Abram Handly Santana wants to understand how the tumor microenvironment contributes to pancreas cancer...

In mice, an experimental drug treatment for Rett syndrome suggests the disorder is reversible

In mice, an experimental drug treatment for Rett syndrome suggests the disorder is reversible

July 27th, 2015

News
Research

A team at Cold Spring Harbor Laboratory find a new approach for treating Rett syndrome, a devastating autism spectrum disorder...

Joni Gladowsky Breast Cancer Foundation donates $80,000 to Cold Spring Harbor Laboratory

Joni Gladowsky Breast Cancer Foundation donates $80,000 to Cold Spring Harbor Laboratory

July 24th, 2015

News
Giving

These proceeds will support breast cancer research in the laboratory of CSHL Professor Nicholas Tonks....

Painting a colorful path of support for autism research

Painting a colorful path of support for autism research

July 22nd, 2015

Blog
Education Giving

Stephanie de Lesseps organizes a color run that earned $10,000 for autism research at CSHL....

Luis A. Mejia, Ph.D., is named 2015 Arnold O. Beckman Postdoctoral Fellow

Luis A. Mejia, Ph.D., is named 2015 Arnold O. Beckman Postdoctoral Fellow

July 22nd, 2015

News
Institutional

Mejia will receive funding for at least two years from the Foundation, works in the laboratory of Dr. Bo Li...

Alumna Elizabeth Murchison follows the evolutionary path of contagious cancer

Alumna Elizabeth Murchison follows the evolutionary path of contagious cancer

July 15th, 2015

News
WSBS

Watson School of Biological Science ‘07 alumna Dr. Elizabeth Murchison studies cancers in domestic dogs, soft-shell clams and Tasmanian devils...

The biggest beast in the Big Data forest? One field’s astonishing growth is, well, ‘genomical’!

The biggest beast in the Big Data forest? One field’s astonishing growth is, well, ‘genomical’!

July 6th, 2015

News
Research

Scientists work to figure out how to capture, store, process and interpret all that genome-encoded biological information....

Alumna Monica Dus discovers the cookie-brain connection

Alumna Monica Dus discovers the cookie-brain connection

July 1st, 2015

News
WSBS

A look at alumna Dr. Monica Dus....

Revised view of brain circuit reveals how we avoid being overwhelmed by powerful odors

Revised view of brain circuit reveals how we avoid being overwhelmed by powerful odors

July 1st, 2015


Research

Researchers discover neural circuit in the mouse olfactory bulb that shows how our mammalian cousins adjust to intense odors....

July 7, 1890 – Official start of first course at the Laboratory

July 7, 1890 – Official start of first course at the Laboratory

June 29th, 2015

News
Institutional

July 7 marks the first day of the first course given at The Brooklyn Institute's Laboratory of Biological Research at Cold Spring Harbor Laboratory. ...

Lending a shore to fellow LI researchers

Lending a shore to fellow LI researchers

June 23rd, 2015

Blog
Research

Long Island University - Post and Adelphi University researchers team up with CSHL to study the Asian shorecrab....

Third-year student Tyler Garvin brings together engineering and medicine to help save lives

Third-year student Tyler Garvin brings together engineering and medicine to help save lives

June 22nd, 2015

News
WSBS

Student researches non-coding mutations responsible for changes in human gene expression....

Joni Gladowsky Breast Cancer Foundation donates $20,000 to CSHL

Joni Gladowsky Breast Cancer Foundation donates $20,000 to CSHL

June 18th, 2015

News
Giving

The event was held at Syosset-Woodbury Community Park and included a Junior Outdoor Hockey Game, an Adult Outdoor Hockey Game and 2 Family Open Skates...

<em>From the Laboratory of Barbara McClintock</em>–Nobel tools inspire award-winning art

From the Laboratory of Barbara McClintock–Nobel tools inspire award-winning art

June 16th, 2015

Blog
History Institutional

Celebrating Barbara McClintock's birthday with a painting by Elizabeth Turnbull inspired by the Nobel laureate....

125th Anniversary Open House draws hundreds to explore Cold Spring Harbor Laboratory

125th Anniversary Open House draws hundreds to explore Cold Spring Harbor Laboratory

June 10th, 2015

News
Institutional

Over 600 people converged on CSHL this past Saturday for the Laboratory’s 125th Anniversary Open House....

Alumnus Niraj Tolia works toward a modern malaria vaccine

Alumnus Niraj Tolia works toward a modern malaria vaccine

June 8th, 2015

News
WSBS

Alumnus receives five-year Investigators in the Pathogenesis of Infectious Disease Burroughs Wellcome Fund grant to fight malaria...

An immune system marker for therapy-resistant prostate cancer

An immune system marker for therapy-resistant prostate cancer

June 4th, 2015

News
Research

Research shows how signaling by an immune system component appears to play an important role in driving particularly aggressive prostate cancer...

Neuroscientists discover how feedback from the cortex helps mammals make fine distinctions about odors

Neuroscientists discover how feedback from the cortex helps mammals make fine distinctions about odors

June 4th, 2015


Research

Researchers study the feedback loop of the olfactory bulb sends output to and receives feedback from multiple parts of the brain...

Pershing Square Foundation establishes $10 million endowment to support CSHL life science research

Pershing Square Foundation establishes $10 million endowment to support CSHL life science research

June 1st, 2015

News
Giving Institutional

The uniquely structured grant reflects a commitment by The Pershing Square Foundation to support exceptional leadership and innovative organizations....

“Science is our candle in the dark”

“Science is our candle in the dark”

May 29th, 2015

Blog
Education WSBS

The remarks of Jack Walleshauser at the 2015 Watson School of Biological Sciences graduation....

Tumor surroundings are shown to affect progression of different cancer subtypes

Tumor surroundings are shown to affect progression of different cancer subtypes

May 27th, 2015

News
Research

Researchers discover that cancer progress differently based on characteristics of the tumor microenvironment....

Scientists pinpoint genes that make stem cells in plants, revealing origin of beefsteak tomatoes

Scientists pinpoint genes that make stem cells in plants, revealing origin of beefsteak tomatoes

May 25th, 2015


Research

Researchers identified a set of genes that control stem cell production in tomato, which affects its size....

Dr. Marja Timmermans, plant geneticist, begins Alexander von Humboldt Professorship in Germany

Dr. Marja Timmermans, plant geneticist, begins Alexander von Humboldt Professorship in Germany

May 21st, 2015

News
Institutional

Timmermans was one of five foreign researchers awarded an Alexander von Humboldt Professorship ...

Scientists discover how a promising anti-leukemia drug harms cancer cells

Scientists discover how a promising anti-leukemia drug harms cancer cells

May 14th, 2015

News
Research

Inhibiting a protein called BRD4 critical to the survival of acute myeloid leukemia (AML) cells has shown to be an effective therapeutic strategy....

Drs. Kepecs and Li honored with 2015 NARSAD Independent Investigator grant awards

Drs. Kepecs and Li honored with 2015 NARSAD Independent Investigator grant awards

May 12th, 2015

News
Research

Dr. Kepecs and Dr. Li received two-year grants to fund their important research....

Using CRISPR, biologists find a way to comprehensively identify anti-cancer drug targets

Using CRISPR, biologists find a way to comprehensively identify anti-cancer drug targets

May 11th, 2015

News
Research

Researchers use CRISPR to find binding pockets inside cancer cells, that when blocked, prevent the cells from proliferating and cause them to die....

Scientists show the mammary gland ‘remembers’ prior pregnancy, spurring milk production

Scientists show the mammary gland ‘remembers’ prior pregnancy, spurring milk production

May 7th, 2015

News
Research

Anecdotal reports of nursing mothers have long suggested that giving milk is a lot easier in second and subsequent pregnancies....

Report shows Cold Spring Harbor Laboratory’s research and education power Long Island, State economies

Report shows Cold Spring Harbor Laboratory’s research and education power Long Island, State economies

May 5th, 2015

News
Institutional

CSHL annually generates $150 million in economic output and accounts for 1,629 jobs and $93 million in earnings; more expected in the future...

WSBS Teaching Award 2015 for Bo Li

WSBS Teaching Award 2015 for Bo Li

April 27th, 2015

News
WSBS

Associate Professor Bo Li wins the Winship Herr Award in 2015....

New signaling pathway discovered in HER2-positive breast cancer, and two potentially powerful drug targets

New signaling pathway discovered in HER2-positive breast cancer, and two potentially powerful drug targets

April 20th, 2015

News
Research

Rsearchers discovered a new pathway, which contains at least two potentially powerful drug targets...

Cold Spring Harbor Laboratory’s 12th commencement ceremony to honor science advocates

Cold Spring Harbor Laboratory’s 12th commencement ceremony to honor science advocates

April 17th, 2015

News
Education WSBS

Charlie Rose, Dr. Hanna Gray, Lord David Sainsbury receive honorary degrees...

Graduation 2015

Graduation 2015

April 17th, 2015

News
WSBS

Sunday, April 19, marks the 12th Watson School commencement, and fittingly, we are awarding twelve Ph.D. degrees....

Cancer researcher Dr. Chris Vakoc to receive AACR’s Outstanding Achievement Award

Cancer researcher Dr. Chris Vakoc to receive AACR’s Outstanding Achievement Award

April 17th, 2015

News
Institutional

Assistant Professor Christopher R. Vakoc, receives the 35th annual AACR Outstanding Achievement in Cancer Research Award...

WSBS Dean Alexander Gann awarded Guggenheim Fellowship in science writing

WSBS Dean Alexander Gann awarded Guggenheim Fellowship in science writing

April 9th, 2015

News
Institutional WSBS

Alexander Gann has been awarded a 2015 Guggenheim Fellowship in science writing....

Study revises standard theory of how PTEN, a critical tumor suppressor, shuts off growth signals

Study revises standard theory of how PTEN, a critical tumor suppressor, shuts off growth signals

April 9th, 2015

News
Research

Scientists discover new evidence explaining precisely how the protein encoded by PTEN (called PTEN) works...

One experiment: Cellular highways carry anti-cancer cargoes

One experiment: Cellular highways carry anti-cancer cargoes

April 9th, 2015

Feature
Research

The gene called PTEN is one of the most important of the body’s natural tumor suppressors....

Thinking about cognition with recent graduate Kristen Delevich

Thinking about cognition with recent graduate Kristen Delevich

April 8th, 2015

News
WSBS

Watson School graduate Kristen Delevich studies how different brain regions communicate with one another ...

Tumor cells that mimic blood vessels could help breast cancer spread to other sites

Tumor cells that mimic blood vessels could help breast cancer spread to other sites

April 8th, 2015

News
Research

“Vascular mimicry” observed in mice could be helping tumors evade anti-angiogenesis drugs...

Scientists discover important communication mechanism between two brain areas implicated in schizophrenia

Scientists discover important communication mechanism between two brain areas implicated in schizophrenia

April 7th, 2015

News
Research

Researchers discover an inhibitory connection between certain brain areas that can control the timing of information flow to the prefrontal cortex ...

Cold Spring Harbor Laboratory thanks Nobelist James Watson for $1 million donation

Cold Spring Harbor Laboratory thanks Nobelist James Watson for $1 million donation

April 6th, 2015

News
Giving Institutional

Dr. Watson donates $1million to the Laboratory in support of biomedical research and education programs....

Cold Spring Harbor Laboratory and North Shore-LIJ announce strategic affiliation to accelerate benefits of cancer research to patients

Cold Spring Harbor Laboratory and North Shore-LIJ announce strategic affiliation to accelerate benefits of cancer research to patients

April 2nd, 2015

News
Institutional

Cold Spring Harbor Laboratory and the North Shore-LIJ Health System announced a strategic affiliation....

Swartz Centers Dedication

Swartz Centers Dedication

April 1st, 2015

News
Giving

An official recognition of Jerome Swartz for his 25+ years of friendship and generous support of Cold Spring Harbor Laboratory neuroscience programs ...

Local business raises over $10,000 for Cold Spring Harbor Laboratory breast cancer research

Local business raises over $10,000 for Cold Spring Harbor Laboratory breast cancer research

March 31st, 2015

News
Giving Institutional

Aboff’s presented a check this month for $10,107 to Cold Spring Harbor Laboratory for breast cancer research....

Cold Spring Harbor Laboratory engages Hairpin Technologies Inc. to license its short hairpin RNA (shRNA) technology

Cold Spring Harbor Laboratory engages Hairpin Technologies Inc. to license its short hairpin RNA (shRNA) technology

March 31st, 2015

News
Institutional

Cold Spring Harbor Laboratory engaged Hairpin Technologies Inc. to expand the commercial distribution and research use of short hairpin RNA....

When thinking about numbers, people estimate a range rather than a single value

When thinking about numbers, people estimate a range rather than a single value

March 30th, 2015

News
Research

Representing numbers as a range of possible values allows people to utilize multiple streams of information, leading to improved decisions...

A unique partnership

A unique partnership

March 24th, 2015

Blog
Education Research

The story of a high school student working with Michael Schatz to create an app that analyzes DNA....

Cold Spring Harbor Laboratory and GSK to develop diabetes and obesity therapeutic

Cold Spring Harbor Laboratory and GSK to develop diabetes and obesity therapeutic

March 23rd, 2015

News
Institutional Research

CSHL announced a collaboration with GSK to develop a treatment for obesity and type 2 diabetes....

Long Island Ph.D. student wins 2015 Harold M. Weintraub award

Long Island Ph.D. student wins 2015 Harold M. Weintraub award

March 11th, 2015

News
Institutional WSBS

Ian Peikon is the 4th Cold Spring Harbor Laboratory graduate student to win the Harold M. Weintraub award...

LI pharma executive joins Cold Spring Harbor Laboratory as General Counsel

LI pharma executive joins Cold Spring Harbor Laboratory as General Counsel

March 10th, 2015

News
Institutional

Charles S. Ryan joins CSHL as the Laboratory’s new General Counsel...

Cancer metabolism and country music with first-year student Jackie Giovanniello

Cancer metabolism and country music with first-year student Jackie Giovanniello

March 9th, 2015

News
WSBS

Student Jackie Giovanniello works to develop better treatment options for patients....

Twin copies of a gene pair up in embryonic stem cells at a critical moment in their differentiation

Twin copies of a gene pair up in embryonic stem cells at a critical moment in their differentiation

March 5th, 2015

News
Research

Team finds that both copies of the Oct4 gene come together just as embryonic stem cells begin to develop into tissue-specific cell types...

22nd Annual Golf Tournament to be held June 16

22nd Annual Golf Tournament to be held June 16

March 2nd, 2015

News
Giving

Cold Spring Harbor Laboratory honors Trudy and Tom Calabrese and celebrates its 22nd Annual Golf Tournament at Piping Rock Club...

Mind-readers: scientists crack a piece of the neural code for learning and memory

Mind-readers: scientists crack a piece of the neural code for learning and memory

March 2nd, 2015


Research

Postmortem brain slices can be “read” to determine how a mouse was trained to behave in response to specific sounds ...

Join CSHL’s TEAM and raise money for breast cancer research

Join CSHL’s TEAM and raise money for breast cancer research

February 25th, 2015


Giving

Join CSHL's TEAM and raise money for breast cancer research...

Stand Up for Suzanne holds breast cancer fundraiser for CSHL

Stand Up for Suzanne holds breast cancer fundraiser for CSHL

February 23rd, 2015

News
Giving

Stand Up for Suzanne held its 2nd annual fundraiser at The Milleridge Cottage....

CSHL quantitative biologist Michael Schatz awarded 2015 Sloan Foundation Research Fellowship

CSHL quantitative biologist Michael Schatz awarded 2015 Sloan Foundation Research Fellowship

February 20th, 2015

News
Research

Associate Professor Michael Schatz receives a 2015 Alfred P. Sloan Foundation Research Fellowship...

Joni Gladowsky Breast Cancer Foundation donates $60,000 to CSHL

Joni Gladowsky Breast Cancer Foundation donates $60,000 to CSHL

February 11th, 2015

News
Giving

Cold Spring Harbor Laboratory is the proud recipient of proceeds from the Joni Gladowsky Breast Cancer Foundation's Tenth Annual Golf Outing...

Making decisions with fourth-year student Kachi Odoemene

Making decisions with fourth-year student Kachi Odoemene

February 9th, 2015

News
WSBS

Student Kachi Odoemene works on studying repression of neuronal activity and contributes to decision-making...

Girls who code (at Cold Spring Harbor)

Girls who code (at Cold Spring Harbor)

February 3rd, 2015

Blog
Education WSBS

Cold Spring Harbor Laboratory joins with Girls Who Code to empower girls into a future in STEM and technology....

In a role reversal, RNAs proofread themselves

In a role reversal, RNAs proofread themselves

January 29th, 2015

News
Research

Molecular photographs of an enzyme bound to RNA reveal a new, inherent quality control mechanism...

Christina Renna Foundation Raises $30,000 for pediatric cancer research at CSHL

Christina Renna Foundation Raises $30,000 for pediatric cancer research at CSHL

January 26th, 2015

News
Giving Institutional

The Christina Renna Foundation presented $30,000 to Cold Spring Harbor Laboratory (CSHL) at their 8th annual Angel's Wish Gala...

Harnessing data from Nature’s great evolutionary experiment

Harnessing data from Nature’s great evolutionary experiment

January 21st, 2015

News
Research

Scientists develop a computational method to estimate the importance of each letter in the human genome...

Fighting pediatric cancer

Fighting pediatric cancer

January 20th, 2015

Blog
Research

A discussion on the mission of Christina Renna Foundation and its fight against pediatric cancers....

A new brain circuit that controls fear is identified

A new brain circuit that controls fear is identified

January 19th, 2015

News
Research

Researchers discover a pathway in that mouse brain that regulates fear memory and behavior ...

3D culture system for pancreatic cancer has potential to change therapeutic approaches

3D culture system for pancreatic cancer has potential to change therapeutic approaches

January 15th, 2015

News
Research

Organoid technology with human tissue provides a model for full progression of the disease...

Mechanistic insights into spinal muscular atrophy suggest new paths for treatment

Mechanistic insights into spinal muscular atrophy suggest new paths for treatment

January 12th, 2015

News
Research

Researchers find that in mouse models of the disease subcutaneous drug administration is sufficient to treat SMA ...

New research on what the nose ‘knows’ reveals an unexpected simplicity

New research on what the nose ‘knows’ reveals an unexpected simplicity

January 11th, 2015


Research

In rats, olfactory bulb neurons use simple ‘linear summation’ to make sense of fluctuating odor inputs from the surrounding environment...

A novel biomarker for mutant p53 could help pathologists assessing tumors during surgery

A novel biomarker for mutant p53 could help pathologists assessing tumors during surgery

January 5th, 2015

News
Research

New discovery may make it easy for cancer surgeons to determine if a patient has a potentially lethal mutation....

Imaging method linking brainwide cell activation & behavior shows what it means for mice to have sex in mind

Imaging method linking brainwide cell activation & behavior shows what it means for mice to have sex in mind

January 5th, 2015

News
Research

Automated method detects activity of neurons during specific behaviors, brainwide, at cellular resolution...

Manhasset Women’s Coalition Against Breast Cancer raises $100,000 to support breast cancer research at CSHL

Manhasset Women’s Coalition Against Breast Cancer raises $100,000 to support breast cancer research at CSHL

December 30th, 2014

News
Giving Institutional

Manhasset Women’s Coalition Against Breast Cancer raises $100,000 to support breast cancer research...

Pink Ribbon Bagels bring nearly $8,500 for breast cancer research at CSHL

Pink Ribbon Bagels bring nearly $8,500 for breast cancer research at CSHL

December 29th, 2014

News
Giving Institutional

The Breast Cancer Research Program as among the beneficiaries of this year's annual Pink Ribbon Bagel campaign....

Neuronal circuits filter out distractions in the brain

Neuronal circuits filter out distractions in the brain

December 15th, 2014

News
Research

Scientists identify a neural pathway that controls attention, with implications for psychiatric disorders ...

Three new trustees elected to Cold Spring Harbor Laboratory Board

Three new trustees elected to Cold Spring Harbor Laboratory Board

December 11th, 2014

News
Institutional

The Board of Directors of Cold Spring Harbor Laboratory (CSHL) elected three new trustees at its November 2014 meeting....

RNA and U with fifth-year student Jack Walleshauser

RNA and U with fifth-year student Jack Walleshauser

December 10th, 2014

News
WSBS

Jack Walleshauser wins the student poster prize at the 2014 in-house symposium....

CSHL team finds a way to make shRNA gene knockdown more effective

CSHL team finds a way to make shRNA gene knockdown more effective

December 5th, 2014

News
Research

Scientists devised a powerful algorithm that improves the effectiveness of research technology harnessing RNA interference ...

Variation in expression of thousands of genes is kept under tight constraint in mice and humans, in all cells and tissues

Variation in expression of thousands of genes is kept under tight constraint in mice and humans, in all cells and tissues

November 19th, 2014


Research

Researchers have identified some 6600 genes whose level of expression varies within a comparatively restricted range in humans and mice...

New investigators join CSHL

New investigators join CSHL

November 14th, 2014

Blog
Research

An interview with newly hired investigators Scott Lyons and Lingbo Zhang....

Double Helix gala raises record $4 million for biomedical research at Cold Spring Harbor Laboratory

Double Helix gala raises record $4 million for biomedical research at Cold Spring Harbor Laboratory

November 13th, 2014

News
Giving Institutional

More than $4 million was raised the evening of November 12 for Cold Spring Harbor Laboratory’s (CSHL) research and education programs....

New junior faculty join CSHL

New junior faculty join CSHL

November 12th, 2014

Blog
Research

Interviews with new junior faculty members Jessica Tollkuhn and Je Lee...

New senior faculty join CSHL

New senior faculty join CSHL

November 10th, 2014

Blog
Research

Interviews with new faculty Adam Siepel and Douglas Fearon....

Re-learning how to read a genome

Re-learning how to read a genome

November 10th, 2014


Research

Study suggests a unified model for how DNA is read, offering insight into how genes evolve...

Some neurons can multitask, raising questions about the importance of specialization

Some neurons can multitask, raising questions about the importance of specialization

November 10th, 2014


Research

New findings challenge assumptions about how information is encoded in the brain...

Mapping the brain with recent graduate Ian Peikon

Mapping the brain with recent graduate Ian Peikon

November 5th, 2014

News
Education WSBS

Ian Peikon, inventor of DIATROL, looks to map all the connections between all of the neurons in the entire brain....

Getting more out of Nature: genetic toolkit finds new maximum for crop yields

Getting more out of Nature: genetic toolkit finds new maximum for crop yields

November 2nd, 2014


Research

An array of gene variants provides “breakthrough benefits” in tomato yield for breeders; other crops next...

Election Day: making medical research a priority

Election Day: making medical research a priority

October 30th, 2014

Blog
Institutional

CSHL partnered Research!America in a bipartisan effort to find out where political candidates stand on research funding....

Cold Spring Harbor Laboratory faces off against a rare cancer with launch of Sarcoma Research Project

Cold Spring Harbor Laboratory faces off against a rare cancer with launch of Sarcoma Research Project

October 30th, 2014

News
Giving Institutional

CSHL is launching a highly targeted effort to combat a rare and deadly type of sarcoma called rhabdomyosarcoma....

Missing sponge gene is found at ‘ghost’ site, proving our oldest common ancestor was more complex than believed

Missing sponge gene is found at ‘ghost’ site, proving our oldest common ancestor was more complex than believed

October 30th, 2014


Research

The last common ancestor of all animals, some 600 million years old, was not as primitive as most experts have assumed....

New study casts sharpest light yet on genetic mysteries of autism

New study casts sharpest light yet on genetic mysteries of autism

October 29th, 2014


Research

Our picture of how genetic errors contribute to autism has just gotten sharper....

Experts convene at CSHL to scrutinize, assess low-dose CT screening for lung cancer

Experts convene at CSHL to scrutinize, assess low-dose CT screening for lung cancer

October 17th, 2014


Research

Nearly two dozen physicians and researchers took a close scientific view of lung cancer progression for diagnostic purposes....

How a molecular Superman protects the genome from damage

How a molecular Superman protects the genome from damage

October 16th, 2014


Research

Scientists find a new role for RNAi protein Dicer in preventing collisions during DNA replication....

In a battle of brains, bigger isn’t always better

In a battle of brains, bigger isn’t always better

October 9th, 2014


Research

Scientists are surprised to find that rats and mice perform similarly in cognitive tests....

Universe to smelliverse with second-year student Daniel Kepple

Universe to smelliverse with second-year student Daniel Kepple

October 8th, 2014

News
WSBS

Daniel Kepple hopes to figure out the chemical and neuronal rules that determine what something smells like...

Rally for medical research Capitol Hill Day

Rally for medical research Capitol Hill Day

September 30th, 2014

Blog
Research

Cristina Aguirre-Chen, Ph.D., a postdoc in Assistant Professor Chris Hammell’s lab discusses her experience at the Rally for Medical Research....

4 CSHL scientists will contribute to President’s BRAIN Initiative under new NIH grants

4 CSHL scientists will contribute to President’s BRAIN Initiative under new NIH grants

September 30th, 2014

News
Research

Four scientists at Cold Spring Harbor Laboratory (CSHL) will perform research in President Obama’s BRAIN Initiative under two new CSHL grants...

Masthead Cove Yacht Club raises $9,500 for CSHL cancer research at annual race

Masthead Cove Yacht Club raises $9,500 for CSHL cancer research at annual race

September 24th, 2014

News
Giving Institutional

The proceeds were donated to support cancer research conducted by CSHL Professor Nicholas Tonks. ...

13th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory

13th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory

September 19th, 2014

News
Giving Institutional

CSHL neuroscientist Dr. Anne Churchland delivers keynote on decision-making ...

Gambling with confidence: Are you sure about that?

Gambling with confidence: Are you sure about that?

September 18th, 2014


Research

Scientists uncover the neural basis of confidence in the rat brain...

Scientists looking across human, fly and worm genomes find shared biology

Scientists looking across human, fly and worm genomes find shared biology

September 8th, 2014


Research

Researchers found that human, fly, and worm genomes have a number of key genomic processes in common, reflecting their shared ancestry....

Welcome to the Watson School

Welcome to the Watson School

September 2nd, 2014

Blog
Education WSBS

A graduate student from the Watson School of Biological Sciences talks about the school's history and programs....

11th annual LI2DAY Walk raises over $525,000 for breast cancer

11th annual LI2DAY Walk raises over $525,000 for breast cancer

August 29th, 2014

News
Giving Institutional

Cold Spring Harbor Laboratory and 17 other breast cancer beneficiary groups received over $525,000 in funding for breast cancer research....

New understanding of a mechanism by which cells try to arrest oncogene action

New understanding of a mechanism by which cells try to arrest oncogene action

August 28th, 2014


Research

What happens inside cells when they detect the activation of a cancer-inducing gene? ...

Matriculation 2014

Matriculation 2014

August 27th, 2014

News
WSBS

A look at the class matriculating in 2014....

CSHL’s Florin Albeanu, Partha Mitra awarded NSF ‘Early Concept’ grants for neuroscience

CSHL’s Florin Albeanu, Partha Mitra awarded NSF ‘Early Concept’ grants for neuroscience

August 18th, 2014


Institutional

Award supports exploratory research with potential for transformative insights – part of BRAIN Initiative...

A shift in the code: new method reveals hidden genetic landscape

A shift in the code: new method reveals hidden genetic landscape

August 18th, 2014

News
Research

Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD...

More than just X and Y: a new genetic basis for sex determination

More than just X and Y: a new genetic basis for sex determination

August 18th, 2014


Research

Researchers identify microRNAs that differentiate male and female fruit flies...

Knowing what to keep and what to trash: how an enzyme distinguishes cellular messages

Knowing what to keep and what to trash: how an enzyme distinguishes cellular messages

August 3rd, 2014


Research

Molecular structure reveals how a protein reads RNAs to preserve stem cell identity ...

CSHL quantitative biologist Michael Schatz wins prestigious NSF Early CAREER Award

CSHL quantitative biologist Michael Schatz wins prestigious NSF Early CAREER Award

July 29th, 2014

News
Institutional Research

The National Science Foundation (NSF) has selected Assistant Professor Michael Schatz, Ph.D to receive its prestigious CAREER Award....

Research may explain how the body’s foremost anti-cancer ‘guardian’ protein learned to switch sides

Research may explain how the body’s foremost anti-cancer ‘guardian’ protein learned to switch sides

July 29th, 2014


Research

Researchers have discovered a new function of the body’s most important tumor-suppressing protein....

“When I grow up…”

“When I grow up…”

July 24th, 2014

Blog
Education

Today, scientists at Cold Spring Harbor Laboratory are working with the community to make sure that kids are exposed to research at a young age...

In development, it’s all about the timing

In development, it’s all about the timing

July 17th, 2014


Research

Closely related organisms share most of their genes, but these similarities belie major differences in behavior, intelligence, and physical appearance...

Scientists propose how antioxidants can accelerate cancers and why they don’t protect against them

Scientists propose how antioxidants can accelerate cancers and why they don’t protect against them

July 10th, 2014


Research

In several trials, antioxidant supplementation has been linked with increased rates of certain cancers....

A summer splicing with first-year student Lital Chartarifsky

A summer splicing with first-year student Lital Chartarifsky

July 9th, 2014

News
WSBS

Lital Chartarifsky, a former URP, and her journey to neuroscience research....

21st annual golf tournament raises over $270,000 for research and education at CSHL

21st annual golf tournament raises over $270,000 for research and education at CSHL

July 9th, 2014

News
Giving Institutional

Laboratory Trustee Ed Travaglianti honored for longstanding service at annual golf outing....

CSHL receives $50 million to establish Simons Center for Quantitative Biology

CSHL receives $50 million to establish Simons Center for Quantitative Biology

July 7th, 2014

News
Institutional

CSHL announced a $50 million gift from Jim and Marilyn Simons to establish the Simons Center for Quantitative Biology....

CSHL’s Dr. Molly Hammell named 2014 Rita Allen Foundation Scholar

CSHL’s Dr. Molly Hammell named 2014 Rita Allen Foundation Scholar

July 1st, 2014

News
Institutional

Dr. Hammell wins an award for young investigators for innovative biomedical research...

CSHL’s Anne Churchland named Pew Scholar and Klingenstein-Simons Fellow

CSHL’s Anne Churchland named Pew Scholar and Klingenstein-Simons Fellow

June 24th, 2014

News
Research

Dr. Churchland receives award that honors excellence in neuroscience and biomedical research ...

Neuroscientists explain how mutated X-linked mental retardation protein impairs neuronal function

Neuroscientists explain how mutated X-linked mental retardation protein impairs neuronal function

June 24th, 2014


Research

There are new clues about malfunctions in brain cells that contribute to intellectual disability and possibly other developmental brain disorders. ...

Big Data meets DNA

Big Data meets DNA

June 17th, 2014

Blog
Research

Postdoctoral researcher Michael Hübner discusses how big data is being used in genomics and disease research....

CSHL breast cancer researcher Mikala Egeblad wins DoD Era of Hope Scholar Award

CSHL breast cancer researcher Mikala Egeblad wins DoD Era of Hope Scholar Award

June 12th, 2014

News
Institutional Research

Dr. Egeblad receives a multi-year, $2.5 million Department of Defense grant to advance cutting-edge breast cancer research   ...

High school students learn the fascinating story of Henrietta Lacks

High school students learn the fascinating story of Henrietta Lacks

June 5th, 2014

Blog
Education

CSHL Director of Research Professor David Spector discusses his visit to the Horace Mann School....

Cold Spring Harbor Laboratory announces settlement in patent malpractice case against Ropes & Gray

Cold Spring Harbor Laboratory announces settlement in patent malpractice case against Ropes & Gray

June 2nd, 2014


Institutional

CSHL ramps up licensing of its short-hairpin RNA technology already used widely in cancer research and drug development...

One experiment: Sometimes our cells express only one gene copy. Why?

One experiment: Sometimes our cells express only one gene copy. Why?

June 1st, 2014

Feature
Research

Professor David L. Spector and team discover some monoallelically expressed genes encoded extra RNA, even though they are missing their other gene....

Unprecedented detail of intact neuronal receptor offers blueprint for drug developers

Unprecedented detail of intact neuronal receptor offers blueprint for drug developers

May 29th, 2014

News
Research

NMDA receptor malfunction is implicated in Alzheimer’s, Parkinson’s, depression, schizophrenia, autism, and stroke...

Dealing with stress—to cope or to quit?

Dealing with stress—to cope or to quit?

May 27th, 2014

News
Research

Researchers identify neurons that determine whether an individual will be depressed or resilient ...

Searching for cancer cures with first-year student Georgi Yordanov

Searching for cancer cures with first-year student Georgi Yordanov

May 21st, 2014

News
WSBS

Student Georgi Yordanov looks to study how cancer cells communicate with the normal cells surrounding them in a tumor....

Putting together the genome with first-year student Maria Nattestad

Putting together the genome with first-year student Maria Nattestad

May 21st, 2014

News
WSBS

Student Maria Nattestad looks to develop a fast and accurate way of putting short DNA sequences back together into the long, linear sequences...

Watson School Graduation 2014

Watson School Graduation 2014

May 21st, 2014

News
WSBS

11 students graduate from the Watson School of Biological Sciences...

Team reports validation of potentially powerful new way to treat HER2-positive breast cancer

Team reports validation of potentially powerful new way to treat HER2-positive breast cancer

May 21st, 2014


Research

Researchers report a discovery that they hope will lead to the development of a powerful new way of treating an aggressive form of breast cancer....

A bad neighborhood for cancer

A bad neighborhood for cancer

May 14th, 2014

Blog
Research

Miriam Fein, a graduate student working in Egeblad lab, ...

Male infertility: it’s all about the package

Male infertility: it’s all about the package

May 13th, 2014


Research

Scientists find a protein that controls DNA organization during sperm development ...

Dr. David Spector, CSHL Professor, is elected to European Molecular Biology Organization

Dr. David Spector, CSHL Professor, is elected to European Molecular Biology Organization

May 7th, 2014


Institutional

European Molecular Biology Organization, has elected CSHL Professor David L. Spector, Ph.D., to its ranks....

Watson School of Biological Sciences celebrates 15th year, confers Ph.D.s on 11th graduating class

Watson School of Biological Sciences celebrates 15th year, confers Ph.D.s on 11th graduating class

May 7th, 2014

News
Institutional WSBS

Watson School celebrates its 15th classes graduation, and Dr. Richard Burgess is awarded an honorary degree ...

Lloyd Trotman receives Pershing Square Sohn Prize for Cancer Research

Lloyd Trotman receives Pershing Square Sohn Prize for Cancer Research

May 5th, 2014


Institutional

Associate Professor Award encourages young investigators to take risks in search of a cure...

Finding the genes that underlie autism

Finding the genes that underlie autism

April 30th, 2014

Blog
Research

Research Assistant Professor Mike Ronemus talks about the importance of understanding the genetics of autism....

Research sees overlap in altered genes found in schizophrenia, autism and intellectual disability

Research sees overlap in altered genes found in schizophrenia, autism and intellectual disability

April 28th, 2014

News
Research

New evidence supports theory that some cases of schizophrenia and autism have malfunctions in some of the same genes are contributing to pathology....

CSHL’s Dr. David Spector is elected to the American Academy of Arts and Sciences

CSHL’s Dr. David Spector is elected to the American Academy of Arts and Sciences

April 25th, 2014

News
Institutional Research

Professor David L. Spector, Ph.D. has been elected to the American Academy of Arts and Sciences....

Dr. Bruce Stillman, CSHL President, wins 2014 Herbert Tabor Research Award

Dr. Bruce Stillman, CSHL President, wins 2014 Herbert Tabor Research Award

April 17th, 2014

News
Institutional

Dr. Bruce Stillman, President of Cold Spring Harbor Laboratory (CSHL), is the 2014 winner of the Herbert Tabor Research Award....

An interview with cancer’s ‘biographer’

An interview with cancer’s ‘biographer’

April 14th, 2014

Blog
Research

An interview with The Emperor of Maladies author Siddartha Mukherjee...

National Science Foundation-sponsored CureNet and CSHL team to improve undergrad research in biology

National Science Foundation-sponsored CureNet and CSHL team to improve undergrad research in biology

March 28th, 2014

News
Education

More than 100 faculty and administrators meet to discuss how to involve more undergraduate students in science research....

Don Monti Memorial Research Foundation gives $500,000 for cancer research at CSHL

Don Monti Memorial Research Foundation gives $500,000 for cancer research at CSHL

March 28th, 2014

News
Giving Institutional

President of the Don Monti Memorial Research Foundation presented Cold Spring Harbor Laboratory with a donation of $500,000....

Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood

Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood

March 27th, 2014


Research

New research indicates a link between certain kinds of early stress and dysfunction in the neuroendocrine system....

For neurons in the brain, identity can be used to predict location

For neurons in the brain, identity can be used to predict location

March 24th, 2014


Research

A new mathematical model uses gene expression data to predict where neurons are located throughout the brain...

Newly identified small-RNA pathway defends genome against the enemy within

Newly identified small-RNA pathway defends genome against the enemy within

March 16th, 2014


Research

microRNAs are found to target ‘jumping genes’ in reproductive cells, protecting against genomic damage...

Celebrating Brain Awareness Week with DNALC’s <em>3D Brain</em>–revolutionizing education in the classroom and the doctor’s office

Celebrating Brain Awareness Week with DNALC’s 3D Brain–revolutionizing education in the classroom and the doctor’s office

March 14th, 2014

Blog
Education Research

The 3D Brain app is an interactive, three-dimensional model of the human brain...

Unravelling a mystery in the ‘histone code’ shows how gene activity is inherited

Unravelling a mystery in the ‘histone code’ shows how gene activity is inherited

March 13th, 2014


Research

Why is histone H3.3 associated with active genes, but histone H3.1 is not?...

What makes a great scientist tick?

What makes a great scientist tick?

March 4th, 2014

Blog
Education Research

Cold Spring Harbor High School student Skyler Palatnick interviews David L. Spector on his career as a cancer researcher....

Ohr Pharmaceutical and CSHL Announce Joint Venture to Develop Trodusquemine and Related Analogs

Ohr Pharmaceutical and CSHL Announce Joint Venture to Develop Trodusquemine and Related Analogs

March 3rd, 2014

News
Institutional

Ohr Pharmaceutical and CSHL announce a new joint venture to develop trodusquemine and related analogs....

CSHL lung cancer researcher receives $70,000 from Swim Across America-Nassau Suffolk

CSHL lung cancer researcher receives $70,000 from Swim Across America-Nassau Suffolk

March 3rd, 2014

News
Giving Institutional

Swim Across America (SAA) Nassau Suffolk Committee distributed the net proceeds of its 2013 Swims to six Long Island and metro area beneficiaries....

Research reveals first glimpse of a brain circuit that helps experience to shape perception

Research reveals first glimpse of a brain circuit that helps experience to shape perception

March 2nd, 2014


Research

For the first time, scientists monitor inhibitory neurons that link sense of smell with memory and cognition in mice...

Nobelist James Watson proposes an unconventional view of type 2 diabetes causation

Nobelist James Watson proposes an unconventional view of type 2 diabetes causation

February 27th, 2014


Research

A new hypothesis of type 2 diabetes causation published in the British medical journal The Lancet...

Like mom or like dad? Some cells randomly express one parent’s version of a gene over the other

Like mom or like dad? Some cells randomly express one parent’s version of a gene over the other

February 24th, 2014


Research

Team finds that some cells activate only one of their two gene copies during development, altering protein yields and raising new questions...

Researchers propose new way to make sense of ‘Big Data’

Researchers propose new way to make sense of ‘Big Data’

February 15th, 2014

News
Research

New application of a classic concept challenges the latest statistical tools....

Scientists discover a new pathway for fear deep within the brain

Scientists discover a new pathway for fear deep within the brain

February 12th, 2014

News
Research

‘Far-reaching’ neurons connect the amygdala with fear response center to control behavior...

Scientists develop powerful new animal model for metastatic prostate cancer

Scientists develop powerful new animal model for metastatic prostate cancer

January 24th, 2014


Research

The new model, known as RapidCaP, reveals a cancer-gene ‘switch’ that drives metastasis ...

Unprecedented structural insights reveal how NMDA receptors can be blocked, to limit neurotoxicity

Unprecedented structural insights reveal how NMDA receptors can be blocked, to limit neurotoxicity

January 22nd, 2014


Research

Structural biologists have obtained important scientific results likely to advance efforts to develop new drugs targeting NMDA receptors in the brain...

Overexpression of splicing protein involved in skin repair causes early changes seen in skin cancer

Overexpression of splicing protein involved in skin repair causes early changes seen in skin cancer

January 19th, 2014


Research

A protein normally involved in healing wounds and maintaining homeostasis in skin tissue is a promoter of invasive and metastatic skin cancers....

Scientists discover two proteins that control chandelier cell architecture

Scientists discover two proteins that control chandelier cell architecture

January 16th, 2014


Research

Chandelier cells, a group of powerful inhibitory neurons, are important in epilepsy and schizophrenia ...