14th annual Double Helix Medals dinner raises over $4 million
News
CSHL’s 2019 Double Helix Medals dinner honored the contributions of Dr. Nancy Wexler and Boomer Esiason.
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Scientists take action to prevent sexual harassment and bias
News
Scientists gathered at Banbury Center last year to discuss ways to prevent gender bias and sexual harassment in science.
High school senior wins big in Breakthrough Junior Challenge
News
Winning the 2019 Breakthrough Junior Challenge, student Jeffery Chen earned his high school a $100,000 science lab designed by the DNA Learning Center.
Historic lab at CSHL transformed for future cancer research
News
NY Governor Andrew Cuomo cut the ribbon for CSHL’s renovated Demerec lab space, marking the beginning of a new chapter for the historied building.
CSHL named Top Long Island Workplace for second year
News
CSHL is named a Top Long Island Workplace by Newsday for the second year in a row.
Researchers double sorghum grain number to improve food supply
News
A set of hormone-controlling genes may be the key to doubling grain number in sorghum plants.
CSHL postdocs receive NARSAD Young Investigator Grants
News
Two CSHL neuroscience postdocs conducting neurobiological and psychiatric research received the 2019 NARSAD Young Investigators grant.
The important role of an Uplands Farm cat
Blog
Cats, Uplands Farm’s smallest employees, have always played a big role in plant care and seed guarding.
Nobel laureate William Kaelin draws a crowd
Blog
Nobel laureate and cancer researcher William Kaelin holds a seminar on his award-winning research at CSHL.
Seeking better treatment for ALS, Lou Gehrig’s disease
News
Researchers found that ‘jumping genes’ were de-silenced in post-mortem tissue samples of ALS patients.
Historic building—groundbreaking science
Feature
The Demerec building has been monumental in scientific history. Now, a $75 million renovation of this celebrated labspace will define CSHL’s future.
One experiment: The shape of norovirus
Feature
Scientists at CSHL examine the structure of a norovirus under the cryo-electron microscope.
Adrian Krainer elected to National Academy of Medicine
News
Professor Adrian Krainer joins the National Academy of Medicine in honor of his groundbreaking work on SMA.
BARseq builds a better brain map
News
Created by CSHL neuroscientists, BARseq is capable of mapping connections within a brain at single-neuron resolution while tracing their gene expression.
Effective vaccines for Lyme disease are needed
News
A new report reiterates the need to stop Lyme disease and defines a strategy for developing effective vaccines against it.
New brain research could change how concussions are treated
News
Blood vessel damage seems to be more widespread than nerve damage in patients with traumatic brain injuries.
Adrian Krainer wins Zülch Prize for lifesaving SMA Treatment
News
Professor Adrian Krainer is awarded the K-J. Zülch Prize for the development and testing of a first-of-its-kind treatment for spinal muscular atrophy.
How Henri Termeer built a biotech giant
News
In a new biography out from CSHL Press, John Hawkins documents Henri Termeer’s legacy in biotechnology.
Mutant cells team up to make an even deadlier blood cancer
News
Two very different mutations have been identified as unexpected partners-in-crime for causing the deadly blood cancer acute myeloid leukemia.
Transparent review in preprints
News
Transparent Review in Preprints (TRiP) enables journals and peer review services to post peer reviews of manuscripts on CSHL’s preprint server bioRxiv.
How to build more trust in science
News
Some of the world’s leading custodians of scientific research integrity met at CSHL’s Banbury Center to find out new ways to build trust in science.
Coffee day quiz
Quiz
Did you know that caffeine is a drug? On international coffee day, explore the chemistry of the infamous drink with our short science quiz.
Discovery could improve MDS cancer treatment
News
Researchers have discovered a promising new target for treating myelodysplastic syndrome (MDS), a common and lethal blood cancer.
Zachary Lippman named 2019 MacArthur Fellow
News
Cold Spring Harbor Laboratory Professor and HHMI Investigator Zachary Lippman has been named a 2019 MacArthur Fellow.
Mice, like humans, fidget when deep in thought
News
Mice seemed to fidget while making decisions, prompting neuroscientists to think more about the connection between movement and cognition.
Peter Koo wants to understand how machines learn biology
News
Dr. Peter Koo joins the CSHL faculty as an assistant professor. His focus is on exploring how artificial intelligence integrates with biology and genomics.
Quiz gone viral
Quiz
Since the Hershey and Chase experiment, scientists have expanded their understanding of viruses. Measure your viral knowledge with our science quiz!
The next agricultural revolution is here
News
After reviewing decades of plant research, scientists suggest that with past lessons and modern tools, the next agricultural revolution is at hand.
The world of Brianna Bibel, The Bumbling Biochemist
Blog
Brianna Bibel, a third-year graduate student at WSBS, is making ripples in the science community through her social media presence.
How one family secured the future of a laboratory
Feature
The Robertson family gifts to CSHL in the early 1970s were of extraordinary importance, for without them the Laboratory might not have survived.
Cancer drugs don’t always work as intended, researchers warn
News
Ten experimental cancer drugs kill tumors in ways that are entirely different than how clinicians thought they did, revealing important insights.
Overcoming resistance in pancreatic cancer
News
Controlling pancreatic tumor proliferation by targeting malignancy-specific resistance pathways in response to AKT and MAPK blockade.
Remembering David Koch
News
CSHL Board of Trustees, faculty and administration mourn the passing of David H. Koch, a supporter of cancer researcher.
Are smart robots a threat?
News
In a Q&A, Neuroscientist Anthony Zador explains how neuroscience can inform machine learning, and why he’s not worried about a robot apocalypse.
Understanding the animal brain could help robots wash your dishes
News
The field of machine learning still has a lot it can glean from neuroscience, especially in how evolution shapes an animal brain.
New brain map could improve AI algorithms for machine vision
News
A revised view of the primate visual system may serve as a future reference for understanding how vision works in humans.
CSHL graduate student wins HHMI fellowship
News
WSBS student David Johnson won a 2019 Gilliam Fellowships for Advanced Study for leadership and diversity in science.
How a lab and its model animals changed science
Feature
The natural history of science at Cold Spring Harbor Laboratory through the lens of animal research.
Understanding pregnancy’s effects on breast cancer risk
News
CSHL researchers authored a review in the journal Cell covering the landscape of breast cancer research.
A survivor’s path to cancer research
Blog
Leukemia survivor and CSHL volunteer Anya Shah talks about her drive to do cancer research and her time in Vakoc lab.
Creature feature quiz
Quiz
Animals have been the muses behind major scientific breakthroughs for ages. See how much you know about the living organisms sharing the Earth with us.
Of mice and model organisms
Feature
An in-depth look at how veterinarians at CSHL help take care of the various organisms that help researchers answer fundamental biological questions.
Urban Barcode Project showcases student research in biodiversity
News
The eighth annual Urban Barcode Project Symposium had young scientists measuring the biodiversity of New York City.
There’s more to smell than meets the nose
Feature
Neuroscience researchers work to figure out our brains process smells, including what features are essential to identifying and separating odors.
Quantifying how the brain smells
News
Neuroscience researchers at CSHL are trying to figure out how the brain processes smells and what features of odors are important in that process.
Sheltzer wins Presidential Early Career Award
News
CSHL Fellow Jason Sheltzer is a recipient of the Presidential Early Career Award for Scientists and Engineers for his work in cancer research.
Laura Slatkin elected to CSHL Board of Trustees
News
Co-founder of NEXT for AUTISM Laura Slatkin joins the Cold Spring Harbor Laboratory Board of Trustees.
Cancer cell’s “self eating” tactic may be its weakness
News
Pancreatic cancer cells are eating their own mitochondria to survive and spread. New research reveals how, hinting at a possible new drug target.
CSHL ranked #1 in research output worldwide
News
The scientific journal Nature named Cold Spring Harbor Laboratory as the top academic research institution in its annual index.
Lee awarded Chan Zuckerberg Initiative Human Cell Atlas grant
News
Assistant Professor Je H. Lee has been named a recipient of one of the Seed Networks for the Human Cell Atlas to study breast tissue.
Sugars that coat proteins are a possible drug target for pancreatitis
News
CA19-9, a complex sugar structure coating proteins, represents a possible drug target for treatment of pancreatitis and prevention of pancreatic cancer.
2019 CSHL Open House was a hit!
News
Over 650 neighbors and science enthusiasts visited the 2019 Open House at CSHL.
Special fibroblasts help pancreatic cancer cells evade immune detection
News
Researchers found a specific type of cancer-associated fibroblast interacts with the immune system to help pancreatic cancer cells stay under the radar.
Cryo-EM illuminates intricate designs of noroviruses
Feature
Researchers reconstruct four different strains of the food-poisoning causing norovirus using the groundbreaking cryo-electron microscope.
Norovirus structures could help develop treatments for food poisoning
News
Researchers at CSHL used cryo-EM to reconstruct the structures of four different strains of human noroviruses, which cause food poisoning.
Fighting cancer in 3D
News
David Tuveson, Director of the CSHL Cancer Center, shares insights about his work on organoid technology.
New preprint server for the health sciences announced today
News
CSHL, Yale University, and BMJ launch medRxiv, a free preprint service for the medical and health sciences.
Plan Universal calls on funders to encourage preprints
News
bioRxiv founders propose new plan to encourage organizations to make research readily available via preprint servers.
Interview with a neuroscientist
Feature
CSHL Professor Bo Li’s lab studies the biology behind mental disorders. Learn more about how Li’s work is changing the way we think about mental health.
Hitting the high notes at the Lab
Blog
The CSHL choir is a cherished tradition, bringing song to some of the Lab’s most important occasions. Learn more about the history of this storied group.
CSHL celebrates 20 years of graduate school at 2019 commencement
News
The Watson School of Biological Sciences held its 16th commencement, with seven researchers graduating with doctoral degrees.
Leading discovery
Feature
Current discoveries about DNA and human genome position CSHL scientists to make life-changing breakthroughs that will improve the human condition.
Honorary degrees to former CSHL leaders
News
From pioneering eukaryotic gene regulation to directing cancer research, here are the alumni being awarded honorary Doctor of Science degrees.
Watson School alumni spotlights
News
This year, Watson School celebrates the 20th anniversary of its first entering class and looks back at some notable alumni from over the years.
Watson School 2019 Ph.D.s
News
Seven students were awarded Ph.D. degrees from Watson School this May. Here, they reflect on their time at the Laboratory as they look to the future.
An essay from the President: Biology for the planet
Feature
CSHL plant scientists are looking for solutions to the biggest questions in agriculture as environments are reshaped by climate change.
Enzyme PHLPP2 could be a viable drug target for treating prostate cancer
News
Researchers have identified an enzyme called Phlpp2 as an attractive drug target for treating prostate cancer.
Remembering John Cairns, CSHL Director, 1963-1968
News
CSHL celebrates the achievements of the late Dr. John Cairns, lab director from 1963 to 1968.
Profile: Doreen Ware champions the plant genome
Feature
Molecular biologist Doreen Ware uses computer science to parse out the genetic roadmaps of plants.
Cryptic mutation is cautionary tale for crop gene editing
Feature
Unexpected interactions between mutations can be a thorn in the side for plant breeders. Scientists unveil what drove one infamous “cryptic” mutation.
Andrea Schorn zooms in on small RNAs in the cell
News
Dr. Andrea Schorn joins CSHL faculty as research assistant professor. Her focus is exploring transposable elements in the genome of mammalian cells.
DNA and pop culture quiz
Quiz
When artistic expression meets gene expression, how well does art imitate life? Take our five-question science IQ quiz to find out.
Cold Spring Harbor Laboratory announces exclusive license with plant breeding start-up Inari
News
CSHL announced a licensing agreement with partner Inari, a company that is advancing plant breeding by tapping nature’s genetic diversity.
Rob Martienssen wins Martin Gibbs Medal for plant research
News
CSHL Professor Rob Martienssen wins the 2019 Martin Gibbs Medal for his contributions to plant biology.
To protect stem cells, plants have diverse genetic backup plans
News
Experts discover how an essential genetic circuit found in all flowering plants, regardless of species, is protected in startlingly different ways.
NIH grant awarded for interneuron research
News
CSHL postdoc Maggie Crow will use her NIH grant to pursue the quantification and analysis of specific types of neurons in the brain.
President Bruce Stillman wins prestigious Gairdner Award
News
Dr. Bruce Stillman, President & CEO of CSHL, has been awarded the 2019 Canada Gairdner International Award for his work on eukaryotic DNA replication.
Crop yield in maize influenced by unexpected gene ‘moonlighting’
News
Yield of the maize plant is tied to activity of a gene called RAMOSA3, but new evidence suggests the gene performs other unexpected functions
Hannah Meyer joins CSHL Quantitative Biology faculty
News
Hannah Meyer is the newest Quantitative Biology Fellow at CSHL, studying how our immune system learns to identify and fight pathogens.
CSHL President elected as AACR Academy Fellow
News
CSHL President and CEO Dr. Bruce Stillman has been elected to the AACR Academy as part of the 2019 Fellows class.
One experiment: Observing cancer’s progress in a mouse prostate
Feature
Using a technique originally designed for mapping brains, two CSHL labs have worked together to image cancer progression in a mouse prostate.
Banbury meeting addresses neurotechnology concerns
News
A white paper written after an important Banbury Center meeting discusses the lack of oversight in direct-to-consumer neurotechnologies.
New cell subtypes classified in mouse brain
News
To map a brain, an intuitive system for classifying neuron types is necessary. Now, a promising approach reveals new cell subtypes in the mouse brain.
Adrian Krainer wins RNA Society’s Lifetime Achievement Award
News
Professor Adrian Krainer was awarded the RNA Society’s Lifetime Achievement Award for his life-saving research.
Congressman Suozzi congratulates CSHL Partner for the Future
News
Partner for the Future Pragati Muthukumar received a special commendation from Congressman Tom Suozzi.
Genetic ‘usual suspects’ identified in researchers’ new list
News
An exhaustive ranked list of “usual suspect” genes involved in disease may prove invaluable for future research and drug discovery.
Chandelier neuron requires ‘Velcro-like’ molecule to form connections
News
How do brain cells network? Researchers have discovered an essential ingredient that facilitates one type of neuron’s many neighborly connections.
Detailed new primate brain atlas could lead to disease insights
News
An international effort has mapped the marmoset brain at an unprecedented level of detail, which brings us closer to understanding the human brain.
Science is a lesson in ‘eye-opening’ for students and teachers
Blog
WSBS graduate student Bruno Gegenhuber embraced teaching at the DNA Learning Center as a learning experience in itself.
What does sight mean to a cancer researcher?
Blog
Postdoc Leah Banks discusses vision’s role in cancer research, and how nearly losing her sight gave her a new perspective on her work.
David McCandlish named Sloan Research Fellow
News
Assistant Professor David McCandlish has been named a 2019 Sloan Research Fellow for his promising work in the field of quantitative biology.
bioRxiv surpasses one million monthly downloads
News
A recent study illustrates the success of bioRxiv, CSHL’s biology preprint server.
Christina Renna Foundation gives $35k for pediatric cancer research
News
The Christina Renna Foundation donated $35,000 to CSHL for continued work on Sarcoma Research Project and research into RMS.
CSHL Scientific Advisory Council member wins Vilcek Prize
News
Dr. Angelika Amon, a member of the CSHL Scientific Advisory Council, wins the Vilcek Foundation Prize for her important work in cell biology.
How does math help us understand the brain?
Feature
An exploration of how computational neuroscientist Tatiana Engel uses math to understand how the brain makes decisions.
CSHL Fellow Jason Sheltzer wins innovation award
News
CSHL Fellow Jason Sheltzer wins the Damon Runyon-Rachleff Innovation Award for his work on cancer.
CSHL Scientific Advisory Council member wins NAS honor
News
Dr. Eve Marder of the CSHL Scientific Advisory Council wins the National Academy of Sciences Award in the Neurosciences.
CSHL donates sheets to veterans in need
News
CSHL donated 75 bags of sheets to the United Veterans Beacon House, with the aid of the Lindenhurst Rotary Club and the Christina Renna Foundation.
Targeting ‘hidden pocket’ for treatment of stroke and seizure
News
Researchers have identified a hidden molecular “pocket” in a special neuron receptor, which could lead to better treatments for stroke and seizures.
Austin’s Purpose donates $10k to neuroscience research
News
Epilepsy research-supporting organization Austin’s Purpose makes a donation to continue key neuroscience research in Professor Hiro Furukawa’s lab.
Statement by Cold Spring Harbor Laboratory addressing remarks by Dr. James D. Watson in “American Masters: Decoding Watson”
News
Statement by Cold Spring Harbor Laboratory addressing remarks by Dr. James D. Watson in “American Masters: Decoding Watson.”
The year of CRISPR
Feature
A look at the various labs across CSHL that utilize CRISPR in their research, and the groundbreaking discoveries they help uncover.
How much are we learning? Natural selection is science’s best critic
News
Researchers determine that natural selection and our evolutionary history may be the best guides for future research.
Taking uncertainty out of cancer prognosis
News
CSHL Fellow Jason Sheltzer has analyzed nearly 20,000 cancer patient histories and genetic data to take the guesswork out of prognosis.
National Academy of Inventors Fellow, Adrian Krainer
News
Professor Adrian Krainer has been named a NAI 2018 Fellow for his work on the first FDA-approved treatment for spinal muscular atrophy.
Big bold dreamers
Feature
Dreamers drive discoveries. CSHL honors its many scientists making big impacts in their respective fields.
Marilyn Simons elected Cold Spring Harbor Laboratory chair
News
Dr. Marilyn Simons becomes the chair of the CSHL Board of Trustees, new officers are elected, and three new trustees join the board.
Breakthrough Prize laureates meet at CSHL
News
Breakthrough Prize winner Adrian Krainer & C. Frank Bennett reunite for the first time since their award ceremony at CSHL to discuss further project.
Molly Hammell wins CZI award for ALS study
News
Associate Professor Molly Hammell wins award for proposed study to find transposable elements that are implicated in ALS.
How the brain hears and fears
News
Researchers are studying how the brain reacts to sounds that it associates with fear, and how easy it is for the brain to learn and unlearn.
Inconspicuous protein key to deadly blood cancer
News
Associate Professor Chris Vakoc and his team find that an aggressive type of leukemia is heavily-dependent on a common protein.
AAAS names two CSHL faculty as 2018 Fellows
News
David Jackson and Jan A. Witkowski were both named 2018 AAAS Fellows for their work in the fields of agriculture and biology.
Pancreatic cancer’s addiction could be its end
News
Researchers may have found a link between improper protein production and the spread of pancreatic cancer.
13th Double Helix Medals dinner raises over $4 million
News
Dr. Priscilla Chan, Mark Zuckerberg, and Dr. Larry Norton were honored for their contributions to basic research at the Double Helix Medals dinner.
A great place to work!
News
CSHL is named a 2018 Top Long Island Workplace by Newsday through the use of employee surveys.
From many mice, unexpected genius
News
Researchers find that some individual mice are smarter than their fellow rodents, which can provide insights into decision-making.
Thanks, National Grid Foundation for hands-on science!
News
The DNA Learning Center has completed the National Grid Advanced Genetics Program (NGAGP) in the Central Islip school district.
Turning cells against pancreatic cancer
News
Researchers have found a way to turn cancer-supporting cells into cells that restrict the cancerous growth in the pancreas.
New regulators of nitrogen use in plants identified
News
A team of CSHL plant biologists identify gene regulators that may help plants utilize nitrogen better and prevent excess nitrogen in soil.
The big problem of small data: A new approach
News
You’ve heard of “big data” but what about small? Researches have crafted a modern approach that could solve a decades-old problem in statistics.
Breakthrough Prize to CSHL professor for SMA research
News
Professor Adrian Krainer has received a Breakthrough Prize in Life Sciences for his work on the first FDA-approved treatment of SMA.
Cancer research from a different perspective
News
CSHL Assistant Professor Tobias Janowitz discusses his patient-centric approach to studying cancer
What’s that smell? Neuroscientists are figuring it out
News
Neuroscientists Florin Albeanu and Alexei Koulakov win the NIH Director’s Transformative Research Award for their project on the olfactory system.
CRISPR could bring groundcherries to market
News
CSHL Professor Zachary Lippman uses CRISPR to make the groundcherry more suitable for large-scale farming
Computational neuroscientist wins BRAIN grant
News
Assistant Professor Tatiana Engel earns grant to build tools that will help build better models of the brain
CSHL podcast wins prestigious PR News award
News
CSHL’s Base Pairs podcast wins the Platinum PR Award for Best Podcast from PR News
How a sleeping cancer awakens and metastasizes
News
Chronic inflammation can reawaken dormant cancer cells and spur metastasis. It may be preventable
Future scientists take to the bench
News
The latest class of the Partners for the Future program visit the Lab and meet their mentors as they get to work
Genomes, justice, and the journey here
Feature
CSHL Professor W. Richard McCombie discusses genomic privacy and sequencing technology in this episode of Base Pairs.
Path to cancer in the brain set by protein CHD5
News
Researchers find that protein keeps neural stem cells from activating too soon and hindering brain development
From workshops to lab work—right next door
Blog
College student James Korossy’s journey from taking workshops at the DNA Learning Center to working at the bench in CSHL Fellow Lingbo Zhang’s lab.
Predicting how splicing errors impact disease risk
News
New research helps correlate genetic mutations with errors in RNA splicing that can cause serious illness
CSHL team wins scientific case competition
News
Five CSHL postdocs and graduate students won first place at the fifth annual Tufts New England Case Competition (TUNECC).
CSHL helps ring opening bell at Nasdaq
News
CSHL Professor Adrian Krainer and his team join the Spinal Muscular Atrophy (SMA) Foundation in ringing the Nasdaq opening bell
Undergrad symposium highlights lessons in the lab
News
The 2018 Undergraduate Research Program class presents their projects after working for ten weeks in various labs across campus.
The miracle of brain development
Feature
In a series of 8 stunning images, CSHL scientists enable us to share the miracle of a brain as it self-assembles
One experiment: Building a brain
Feature
A genetic program precisely guides development of a part of the brain
Dr. Zador wins Transformative Investigator award
News
CSHL professor Anthony Zador wins Gill Symposium prize for his innovative work on MAPseq
Seeding citizen science with DNA barcoding
News
Teachers trained in DNA barcoding can mentor students as they become citizen scientists investigating what interests them most.
Big plans for a tiny plant
Feature
On this episode of Base Pairs, Rob Martienssen discusses how duckweed could be the next biofuel and help combat climate change
Massive genome havoc in breast cancer is revealed
News
Researchers have made a highly detailed map of 20,000 structural variations in a cancer cell’s genome
CSHL Fellow Semir Beyaz wins three awards
News
Semir Beyaz has won three awards for his research on the impact of dietary choices on the body’s immunity against cancer
Nicholas Tonks wins prestigious ASBMB award
News
Professor Nicholas Tonks wins Earl and Thressa Stadtman Distinguished Scientist Award from the American Society for Biochemistry and Molecular Biology
CSHL spinoff wins investment prize
News
CSHL spinoff company MapNeuro Inc., which uses tech developed in Zador lab, wins 2018 Seed Capital Prize from Alexandria LaunchLabs
Progress toward improved Wilson’s disease drug
News
Encouraging early results in a potential new treatment for Wilson's disease.
Researchers discover new type of lung cancer
News
Researchers have discovered a new form of lung cancer.
Postdoc wins Indian National Science Academy prize
News
Dhananjay Huilgol, a postdoc in Professor Joshua Huang’s lab, wins one of India’s highest honors for young investigators
Being a scientist means being part of a team
Blog
High school senior Jerinna Solages learns what it’s really like to do scientific research in CSHL’s Partners for the Future program.
The case for open and inclusive science
Feature
America must continue to a place where the most talented people in the world want to live, study and work.
Nation’s cancer centers endorse HPV vaccination
News
Dr. Stillman and Dr. Tuveson joined with the leaders of other institutions nationwide in endorsing a statement regarding the HPV vaccine
Alexander Dobin dives into genomic data
News
Alexander Dobin joins the faculty as its newest assistant professor, working on the computational side of genomics research
Suffrage Science award to Mikala Egeblad
News
Egeblad and 10 other female scientists from around the world were presented with heirloom jewelry at the Suffrage Science awards ceremony.
A better way to trace neuronal pathways
News
Researchers have improved a key method used to map circuits in the brain
Microbial masterpieces win ASM Agar Art Contest
News
Science-inspired artworks created at CSHL’s DNA Learning Center win in the 2018 American Society for Microbiology Agar Art Contest
Organoid profiling personalizes treatments for pancreatic cancer
News
Pancreatic organoids grown from patients' tumors make precision medicine possible
A science writer’s quest to understand heredity
Blog
LabDish spoke with science writer Carl Zimmer about what he learned about heredity as he zig-zagged through CSHL while writing his new book.
Prof. Zachary Lippman named Blavatnik Award finalist
News
Professor Zachary Lippman was chosen as a Finalist in Life Sciences for the 2018 Blavatnik National Awards
Scientists show how brain circuit generates anxiety
News
Researchers have identified a circuit in the brain that drives anxiety
CSHL’s Zachary Lippman named HHMI Investigator
News
CSHL Professor Zach Lippman is selected as an HHMI investigator, in recognition of his innovative work in the field of plant genetics
Pershing Square Sohn prize to Camila dos Santos
News
Assistant Professor Camila dos Santos, Ph.D., has been awarded the Pershing Square Sohn Prize for Young Investigators in Cancer Research.
How do plants know when to flower?
Blog
Colorful flowers are a sure sign of spring. But how do flowering plants know that it is time to bloom?
How pancreatic cancer spreads after surgery
News
Researchers have solved a mystery about how pancreatic cancer spreads
The immune system, unleashed
Feature
Cancer immunotherapy has a long and storied history, one that begins with a young woman suffering from a pain in her hand
High schoolers reveal fraudulent herbal medicines
News
Some herbal products are not what they claim to be. These high school students and their mentor used DNA to investigate
Nature’s masterpiece: the brain
Feature
A message from President and CEO Dr. Bruce Stillman from the Spring 2018 Harbor Transcript on the innovative research happening at CSHL
How key brain receptor works in hostile conditions
News
A structural variation enables a key brain receptor to function in a hostile environment
Bringing immune cells back into the cancer fight
Feature
Doug Fearon used a mouse model to discover how pancreatic cancer hides from the immune system.
Cold Spring Harbor Laboratory celebrates its 15th commencement
News
Five students from the Watson School of Biological Sciences graduate, with special keynote speeches from Drs. David and Leon Botstein
Therapeutic RNA corrects splicing defect that causes familial dysautonomia
News
A team provides proof of concept for an RNA drug correcting an error in RNA splicing that causes familial dysautonomia (FD)
Portrait of a Neuroscience Powerhouse
Feature
A relatively small neuroscience group at CSHL is having an outsized impact on a dynamic and highly competitive field
Watson School 2018 Ph.D.s
News
CSHL celebrates its 15th commencement, with five promising Ph.D. students graduating and honorary degrees presented to David and Leon Botstein
David Tuveson elected to the AACR Board of Directors
News
CSHL Professor David Tuveson was elected to the Board of Directors of the American Association for Cancer Research for the 2018 - 2021 term
Newly identified genetic mutation results in intellectual disability and developmental delay
News
Scientists have identified a new illness caused by a genetic mutation that gives rise to a wide range of symptoms including intellectual disability
CSHL’s Base Pairs is a finalist for the 2018 Webby Awards
News
CSHL's podcast Base Pairs was nominated for a prestigious Webby award for best Science and Education podcast
Andrew Whiteley appointed VP of Business Development and Technology Transfer at CSHL
News
Life science business leader Andrew Whiteley becomes the Vice President of CSHL's Business Development and Technology Transfer department.
Study reveals a way to make prostate cancer cells run out of energy and die
News
In lethal prostate cancer, the gene PTEN is often missing. In such cases, one effective treatment may be to administer drugs that inhibit mitochondria
Research profile: Robert Maki
Feature
Straddling CSHL and Northwell Health gives Dr. Maki the perspective he needs to bring cancer research closer to the practice of treating patients
The course to science stardom
Feature
At least 10 CSHL Courses alumni have gone on to win a Nobel Prize, while others have become leaders of major scientific institutions
Revolutionary brain-mapping technique provides new blueprint for cortical connections
News
Researchers used MAPseq, a revolutionary brain mapping method, to make a discovery that will force neuroscientists to rethink how areas of the cortex
Evans Foundation MDS Young Investigator Award to Lingbo Zhang
News
CSHL Fellow Lingbo Zhang received a Young Investigator Award from the Edward P. Evans Foundation.
One experiment: Twice the tomatoes
Feature
Zachary Lippman’s team found a way to boost tomato yield by digging into the plant’s genome and fine-tuning its branching patterns.
Unique communication strategy discovered in pathway controlling plant growth
News
Scientists have identified a receptor on plant stem cells that can issue different instructions about how the plant will grow.
The cancer answer that wasn’t
Feature
We look at the "reproducibility crisis" in science, with a cancer researcher discovering something he didn't expect while experimenting with MELK
Ratner and Weisbrod join Cold Spring Harbor Laboratory Board of Trustees
News
Bruce Ratner and Stuart Weisbrod were elected to the Cold Spring Harbor Laboratory Board of Trustees
CRISPR-based system identifies important new drug targets in a deadly leukemia
News
CRISPR was used to find 2 new druggable targets in a deadly leukemia
Kids today are doing what forensics experts couldn’t just 25 years ago
Blog
An 11-year-old student uses DNA testing to try to solve a 5,000-year-old murder mystery at CSHL’s DNA Learning Center.
New method identifies splicing biomarkers for liver cancer
News
Researchers have developed a method for identifying splicing-based biomarkers for liver cancer
New CSHL Fellow studies nexus of diet, metabolism, and cancer
News
CSHL Fellow Semir Beyaz works on the effects of what we eat and how it affect the incidence of colorectal cancers.
One experiment: When cancer is hiding in plain sight
Feature
Douglas Fearon's team is figuring out how to get immune cells to recognize—and kill—pancreatic cancer cells
The secret to tripling the number of grains in sorghum and perhaps other staple crops
News
A simple genetic modification can triple grain production in sorghum, a drought-tolerant plant that is an important source of food and animal feed.
Science self-corrects: cancer gene does not pass reproducibility test
News
CSHL Fellow Jason Sheltzer and his research team use CRISPR to discover that MELK is not actually involved in cancer.
Autism genetics study calls attention to impaired motor skills, general cognitive impairment
News
New research on the genetic causes of autism calls attention to diminished motor skills and suggests the importance of broad cognitive impairment
PLOS and CSHL enter agreement to enable preprint posting on bioRxiv
News
The Public Library of Science (PLOS) will now be automatically posting papers submitted to its journal on bioRxiv, CSHL's preprint server
Welcome to the real world of science, I’ll be your guide
Blog
Jackie Novatt was determined to show the people on her campus tours how science really works—and landed her dream job in the process.
Dr. Leemor Joshua-Tor honored with Mildred Cohn Award from ASBMB
News
Professor Leemor Joshua-Tor receives the American Society for Biochemistry and Molecular Biology’s 2018 Mildred Cohn Award in Biological Chemistry.
More rice, please: 13 rice genomes reveal ways to keep up with ever-growing population
News
Rice provides 20% of calories consumed. As the population grows toward 9 billion and the climate shifts, we'll need to grow more rice in more places.
At CSHL, Congressman Suozzi celebrates scientific achievements of local HS students
News
Congressman Suozzi hosts congratulatory event at CSHL for high school science competition winners, including two Partners for the Future participants.
Evolving sets of gene regulators explain some of our differences from other primates
News
What makes us different from our primate relatives? Gene regulation is one important evolutionary factor
New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes
News
CSHL scientists have designed software that enables biologists to determine with unprecedented accuracy how much protein a given cell is making.
45 years later, a scientist realizes he’s a star
Blog
David Haas was stunned to learn the impact of work he abandoned decades ago. He took a CSHL course to see it for himself.
Christina Renna Foundation raises $30,000 for continuing pediatric cancer research at CSHL
News
The Christina Renna Foundation donates over $30,000 for rhabdomyosarcoma research, and honors Associate Professor Chris Vakoc with its research award
CSHL’s Rob Martienssen honored with prestigious Barbara McClintock Prize
News
Plant geneticist Rob Martienssen awarded prestigious McClintock Prize.
Counting chromosomes: Plant scientists solve a century-old mystery about reproduction
News
Geneticists have solved a century-old mystery by discovering a remarkable mechanism that enables plants to count their chromosomes
Turning off the immune system is hard. Turning it on against cancer is easier.
Blog
How Professor Doug Fearon’s experiences with autoimmune disease patients contributed to the discovery of a new potential immunotherapy for cancer.
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