CSHL Stories and Media archive for Tag: structural biology

DNA replication: A game of precision

4/25/2021

A highly choreographed complex of molecules is vital to starting and synchronizing DNA replication during cell division. Read the story »

How to tame a restless genome

4/8/2021

CSHL researchers found a mechanism to keep otherwise mobile genetic elements in place in the genome. Read the story »

How human cells coordinate the start of DNA replication

3/23/2021

Researchers discover how human cells regulate DNA replication, an important part of cell division, in time and space. Read the story »

Joshua-Tor wins Biophysical Society honor

11/16/2020

CSHL Professor and HHMI Investigator Leemor Joshua-Tor was named a 2021 Fellow of the Biophysical Society for her work on RNAi and DNA replication. Read the story »

The “ORC” twists, pinches, and dances around DNA

9/16/2020

The Origin Recognition Complex (ORC) is a key piece of cellular machinery, fundamental to life, yet so far mysterious. Watch the video »

Replicating a genome starts with a twist, a pinch, and a bit of a dance

9/16/2020

Researchers have their first high resolution look at how “ORC,” a human protein complex essential to life, moves. Read the story »

What do these scientist moms do? Ask their kids.

5/8/2020

We asked the children of three scientists to describe their mother’s work. See what they had to say. Read the story »

Images of ‘invisible’ holes on cells may jumpstart research

3/3/2020

Cellular pores, once impossible to see, have been imaged for the first time. This sets the stage for new discoveries about blood pressure and pain. Read the story »

Cracking the case of the norovirus

2/6/2020

A pervasive virus has evaded vaccine developers for decades. By getting a clear look at its protective shell, they may finally know how to defeat it. Read the story »

New look at odd holes involved in taste, Alzheimer’s, asthma

1/27/2020

Large holes in our cells have been implicated in depression, Alzehimer’s disease, asthma, and even taste. Now, we know what two of these pores look like. Read the story »

One experiment: The shape of norovirus

10/25/2019

Scientists at CSHL examine the structure of a norovirus under the cryo-electron microscope. Read the story »

Quiz gone viral

Since the Hershey and Chase experiment, scientists have expanded their understanding of viruses. Measure your viral knowledge with our science quiz! Take the quiz »

Cryo-EM illuminates intricate designs of noroviruses

6/11/2019

Researchers reconstruct four different strains of the food-poisoning causing norovirus using the groundbreaking cryo-electron microscope. Read the story »

Norovirus structures could help develop treatments for food poisoning

6/11/2019

Researchers at CSHL used cryo-EM to reconstruct the structures of four different strains of human noroviruses, which cause food poisoning. Read the story »

How key brain receptor works in hostile conditions

5/9/2018

A structural variation enables a key brain receptor to function in a hostile environment Read the story »