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CSHL Stories and Media archive for Tag: alzheimers

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Brain receptor pulls open electrical gate like a puppet master

6/30/2020

When stimulated by a neurotransmitter or drug, the NMDA receptor pulls open an ion gate that allows ions to flow. Read the story »

3D image of CALHM (calcium homeostasis modulators) pore

New look at odd holes involved in taste, Alzheimer’s, asthma

1/27/2020

Large holes in our cells have been implicated in depression, Alzehimer’s disease, asthma, and even taste. Now, we know what two of these pores look like. Read the story »

New tool for investigating brain cells, Parkinson’s, & more

1/22/2020

Researchers have created a new chemical tool for revealing how specific types of brain cell receptors function in the brain. Watch the video »

New tool for investigating brain cells, Parkinson’s, & more

1/22/2020

Researchers have crafted a compound for targeting specific brain cell receptors, creating new opportunities to study the brain and Parkinson’s disease. Read the story »

The non-human living inside of you

1/9/2020

A large part of human DNA doesn’t aid the normal workings of the body. This “junk DNA” contains ancient viruses that may spur diseases like ALS. Read the story »

How key brain receptor works in hostile conditions

5/9/2018

A structural variation enables a key brain receptor to function in a hostile environment Read the story »

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

12/1/2016

Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia. Read the story »

GluN1a/GluN2B NMDA receptors calcium-binding

Unprecedented detail of intact neuronal receptor offers blueprint for drug developers

5/29/2014

NMDA receptor malfunction is implicated in Alzheimer’s, Parkinson’s, depression, schizophrenia, autism, and stroke Read the story »

Israel and Lavine select CSHL to announce initiative to make NY center of Alzheimer’s research

6/20/2013

Congressman Israel and Assemblyman Lavine select Cold Spring Harbor Laboratory to announce initiative to make NY the center of Alzheimer's research Read the story »

One experiment: Capturing a drug in its binding pocket

6/1/2013

Erkan Karakas, a post-doc in Hiro Furukawa's lab, finds an elusive binding pocket that could help in the treatment of neurodegenerative diseases. Read the story »

Scientists reverse Alzheimer’s-like memory loss in animal models by blocking EGFR signaling

9/24/2012

EGFR inhibitors used to fight cancer show surprising efficacy in fly, mouse models of beta amyloid-associated memory loss Read the story »

Storm of ‘awakened’ transposons may cause brain-cell pathologies in ALS, other illnesses

9/4/2012

A team of neuroscientists and informatics experts at CSHL reports important progress today in an effort to understand the relationship between transpo Read the story »

Unexpected signaling role for foul-smelling hydrogen sulfide in cell response to protein misfolding

12/13/2011

Hydrogen sulfide plays an important role in the regulation of a signaling pathway implicated in biological malfunctions linked to Alzheimer’s. Read the story »

Alzheimer’s disease: A CSHL study cited as a key advance

5/4/2011

CSHL's Yi Zhong explores a specific peptide in the brain, which could be a viable target for therapeutic intervention for alzheimer's disease. Read the story »

CSHL scientists identify elusive neuronal targets of deep brain stimulation

12/15/2010

Study might provide new clues to designing better treatments for depression and other neuropsychiatric disorders Read the story »

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CSHL Stories and Media archive for Tag: alzheimers

Filter by tag

Brain receptor pulls open electrical gate like a puppet master

New look at odd holes involved in taste, Alzheimer’s, asthma

New tool for investigating brain cells, Parkinson’s, & more

New tool for investigating brain cells, Parkinson’s, & more

The non-human living inside of you

How key brain receptor works in hostile conditions

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

Unprecedented detail of intact neuronal receptor offers blueprint for drug developers

Israel and Lavine select CSHL to announce initiative to make NY center of Alzheimer’s research

One experiment: Capturing a drug in its binding pocket

Scientists reverse Alzheimer’s-like memory loss in animal models by blocking EGFR signaling

Storm of ‘awakened’ transposons may cause brain-cell pathologies in ALS, other illnesses

Unexpected signaling role for foul-smelling hydrogen sulfide in cell response to protein misfolding

Alzheimer’s disease: A CSHL study cited as a key advance

CSHL scientists identify elusive neuronal targets of deep brain stimulation

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