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CSHL Stories and Media archive for Tag: Alzheimer’s

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A new look at brain function and psychiatric disorders

11/2/2022

CSHL scientists’ new 3D models of NMDA brain receptor variants could lead to better treatments for schizophrenia, stroke, depression, and Alzheimer’s. Read the story »

Mapping brain disorder therapeutics at work

7/29/2022

Dive into the 3D atomic structure of the NMDA receptor, important in several brain disorders, and see how it interacts with drugs that inhibit it. Watch the video »

Mapping out new routes to treat brain disorders

6/10/2022

CSHL scientists explore new angles to improve brain disorder therapies with 3D maps of the NMDA receptor, a key player in Alzheimer's and epilepsy. Read the story »

Picky proteins: A new angle for brain disorder therapeutics

5/20/2022

Researchers have designed an antibody that may help treat brain disorders. See how it prevents neurons from malfunctioning. Watch the video »

Brain receptor pulls open electrical gate like a puppet master

6/30/2020

When stimulated by a neurotransmitter or drug, the NMDA receptor pulls open an ion gate that allows ions to flow. Read the story »

3D image of CALHM (calcium homeostasis modulators) pore

New look at odd holes involved in taste, Alzheimer’s, asthma

1/27/2020

Large holes in our cells have been implicated in depression, Alzehimer’s disease, asthma, and even taste. Now, we know what two of these pores look like. Read the story »

New tool for investigating brain cells, Parkinson’s, & more

1/22/2020

Researchers have created a new chemical tool for revealing how specific types of brain cell receptors function in the brain. Watch the video »

New tool for investigating brain cells, Parkinson’s, & more

1/22/2020

Researchers have crafted a compound for targeting specific brain cell receptors, creating new opportunities to study the brain and Parkinson’s disease. Read the story »

The non-human living inside of you

1/9/2020

A large part of human DNA doesn’t aid the normal workings of the body. This “junk DNA” contains ancient viruses that may spur diseases like ALS. Read the story »

How key brain receptor works in hostile conditions

5/9/2018

A structural variation enables a key brain receptor to function in a hostile environment Read the story »

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

12/1/2016

Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia. Read the story »

GluN1a/GluN2B NMDA receptors calcium-binding

Unprecedented detail of intact neuronal receptor offers blueprint for drug developers

5/29/2014

NMDA receptor malfunction is implicated in Alzheimer’s, Parkinson’s, depression, schizophrenia, autism, and stroke Read the story »

Israel and Lavine select CSHL to announce initiative to make NY center of Alzheimer’s research

6/20/2013

Congressman Israel and Assemblyman Lavine select Cold Spring Harbor Laboratory to announce initiative to make NY the center of Alzheimer's research Read the story »

One experiment: Capturing a drug in its binding pocket

6/1/2013

Erkan Karakas, a post-doc in Hiro Furukawa's lab, finds an elusive binding pocket that could help in the treatment of neurodegenerative diseases. Read the story »

Scientists reverse Alzheimer’s-like memory loss in animal models by blocking EGFR signaling

9/24/2012

EGFR inhibitors used to fight cancer show surprising efficacy in fly, mouse models of beta amyloid-associated memory loss Read the story »

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CSHL Stories and Media archive for Tag: Alzheimer’s

Filter by tag

A new look at brain function and psychiatric disorders

Mapping brain disorder therapeutics at work

Mapping out new routes to treat brain disorders

Picky proteins: A new angle for brain disorder therapeutics

Brain receptor pulls open electrical gate like a puppet master

New look at odd holes involved in taste, Alzheimer’s, asthma

New tool for investigating brain cells, Parkinson’s, & more

New tool for investigating brain cells, Parkinson’s, & more

The non-human living inside of you

How key brain receptor works in hostile conditions

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

Unprecedented detail of intact neuronal receptor offers blueprint for drug developers

Israel and Lavine select CSHL to announce initiative to make NY center of Alzheimer’s research

One experiment: Capturing a drug in its binding pocket

Scientists reverse Alzheimer’s-like memory loss in animal models by blocking EGFR signaling

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