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CSHL Stories and Media archive for Tag: RNA therapeutics

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photo of breast cancer tumor cross section

Can cancer be treated by changing its cells?

4/11/2022

Tumors grow when cells lose their biological identity. A promising therapeutic might restore their sense of self. Read the story »

image of a mouse liver tissue with cancer tumor

Cutting off liver cancer’s nutrient supply chain

2/3/2022

CSHL researchers developed a way to interfere with the energy pathway that allows liver cancer to grow and spread. Read the story »

Editing RNA to fix protein problems in cystic fibrosis

1/27/2022

CSHL researchers found a new way to address a previously untreatable class of mutations in the cystic fibrosis gene. Read the story »

illustration of a single strand ribonucleic acid

The rise of RNA therapeutics

10/14/2021

RNA has been making waves as a new approach to prevent or treat diseases, including COVID-19 and spinal muscular atrophy. Read the story »

photo of Maria Luisa Pineda working in a lab

Envisagenics and Biogen partner for RNA splicing research

6/9/2021

CSHL spin-out company Envisagenics teams up with Biogen to advance research in RNA-based therapeutics for central nervous system diseases. Read the story »

image of cancer cell movement and metastases

Regulatory RNAs promote breast cancer metastasis

12/22/2020

A gene-regulating bit of RNA promotes breast cancer metastasis. Agents that destroy that RNA provide hope for a new drug. Read the story »

photo of Adrian Krainer and Mohammad Alinoor Rahman observing results

Mutation’s role in blood cancers revealed by ideal team-up

1/31/2020

Researchers from CSHL and MSKCC have determined how a mutation implicated in many blood cancers reduces the proteins that make healthy blood cells. Read the story »

graphic of title card from Mutations in Blood Cancers video

Mutation’s role in blood cancers revealed by ideal collaboration

1/31/2020

Researchers from CSHL and MSKCC have determined how a mutation implicated in many blood cancers reduces the proteins that make healthy blood cells. Watch the video »

Andrea Schorn zooms in on small RNAs in the cell

4/29/2019

Dr. Andrea Schorn joins CSHL faculty as research assistant professor. Her focus is exploring transposable elements in the genome of mammalian cells. Read the story »

A promising new strategy to combat familial dysautonomia

5/17/2018

Scientists determine how to correct the error in RNA splicing that causes familial dysautonomia, a rare inherited neurodegenerative disorder. Watch the video »

Therapeutic RNA corrects splicing defect that causes familial dysautonomia

4/30/2018

A team provides proof of concept for an RNA drug correcting an error in RNA splicing that causes familial dysautonomia (FD) Read the story »

New method identifies splicing biomarkers for liver cancer

3/2/2018

Researchers have developed a method for identifying splicing-based biomarkers for liver cancer Read the story »

FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL

12/24/2016

Nusinersen (Spinraza) will be used to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA). Read the story »

One experiment: A drug for SMA visibly repairs defective cells

12/1/2016

Professor Adrian Krainer develops a treatment for spinal muscular atrophy, the leading genetic cause of infant death. Read the story »

Non-coding portions of genome are found to play role in cancer

9/27/2016

CSHL scientists test an antisense method of targeting long noncoding RNAs overexpressed in breast cancers. Read the story »

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