Regulatory RNAs promote breast cancer metastasis 12/22/2020 A gene-regulating bit of RNA promotes breast cancer metastasis. Agents that destroy that RNA provide hope for a new drug. Read the story »
Mutation’s role in blood cancers revealed by ideal team-up 1/31/2020 Researchers from CSHL and MSKCC have determined how a mutation implicated in many blood cancers reduces the proteins that make healthy blood cells. Read the story »
Mutation’s role in blood cancers revealed by ideal collaboration 1/31/2020 Researchers from CSHL and MSKCC have determined how a mutation implicated in many blood cancers reduces the proteins that make healthy blood cells. Watch the video »
Andrea Schorn zooms in on small RNAs in the cell 4/29/2019 Dr. Andrea Schorn joins CSHL faculty as research assistant professor. Her focus is exploring transposable elements in the genome of mammalian cells. Read the story »
A promising new strategy to combat familial dysautonomia 5/17/2018 Scientists determine how to correct the error in RNA splicing that causes familial dysautonomia, a rare inherited neurodegenerative disorder. Watch the video »
Therapeutic RNA corrects splicing defect that causes familial dysautonomia 4/30/2018 A team provides proof of concept for an RNA drug correcting an error in RNA splicing that causes familial dysautonomia (FD) Read the story »
New method identifies splicing biomarkers for liver cancer 3/2/2018 Researchers have developed a method for identifying splicing-based biomarkers for liver cancer Read the story »
FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL 12/24/2016 Nusinersen (Spinraza) will be used to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA). Read the story »
One experiment: A drug for SMA visibly repairs defective cells 12/1/2016 Professor Adrian Krainer develops a treatment for spinal muscular atrophy, the leading genetic cause of infant death. Read the story »
Non-coding portions of genome are found to play role in cancer 9/27/2016 CSHL scientists test an antisense method of targeting long noncoding RNAs overexpressed in breast cancers. Read the story »
Adrian Krainer of Cold Spring Harbor Laboratory elected to American Academy of Arts and Sciences 4/20/2016 Adrian Krainer was elected to the American Academy of Arts and Sciences. Read the story »
Unusual drug target and drug generate exciting preclinical results in mouse models of metastatic breast cancer 12/22/2015 Researchers publish preclinical data suggesting the promise of a novel drug directed against a novel target n malignant mammary tumors. Read the story »
Team uses antisense technology that exploits gene splicing mechanism to kill cancer cells 11/3/2012 Researchers find method to target the cancer cell's metabolic process to destroy it. Read the story »
CSHL-led team introduces new method to closely model diseases caused by splicing defects 8/15/2012 Researchers find novel method of making animal models for human genetic disease research. Read the story »
CSHL announces collaboration to speed development of new cancer therapies 6/13/2012 Short hairpin RNA collection applied to advanced mouse models aims to accelerate drug target validation. Read the story »