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Enzyme PHLPP2 could be a viable drug target for treating prostate cancer

May 15, 2019

Researchers have identified an enzyme called Phlpp2 as an attractive drug target for treating prostate cancer.

One experiment: Observing cancer’s progress in a mouse prostate

March 14, 2019

Using a technique originally designed for mapping brains, two CSHL labs have worked together to image cancer progression in a mouse prostate.

Study reveals a way to make prostate cancer cells run out of energy and die

April 3, 2018

In lethal prostate cancer, the gene PTEN is often missing. In such cases, one effective treatment may be to administer drugs that inhibit mitochondria

Researchers identify “Achilles’ heel” of PTEN that helps drive prostate cancer progression

February 13, 2017

Researchers at CSHL have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it.

No (real) moustache required to join the “Movember” party

November 15, 2016

Members of Trotman don fake moustaches in order to raise money for prostate cancer research during Movember.

Movember: Fighting for health in the Lab and the gym

November 20, 2015

Dawid Nowak discusses the difficulties and challenges involved in understanding pancreatic cancer.

Third-year student Abram Handly Santana explores the pancreatic tumor microenvironment

August 1, 2015

Abram Handly Santana wants to understand how the tumor microenvironment contributes to pancreas cancer.

An immune system marker for therapy-resistant prostate cancer

June 4, 2015

Research shows how signaling by an immune system component appears to play an important role in driving particularly aggressive prostate cancer

Pershing Square Foundation establishes $10 million endowment to support CSHL life science research

June 1, 2015

The uniquely structured grant reflects a commitment by The Pershing Square Foundation to support exceptional leadership and innovative organizations.

Study revises standard theory of how PTEN, a critical tumor suppressor, shuts off growth signals

April 9, 2015

Scientists discover new evidence explaining precisely how the protein encoded by PTEN (called PTEN) works

One experiment: Cellular highways carry anti-cancer cargoes

April 9, 2015

The gene called PTEN is one of the most important of the body’s natural tumor suppressors.

A novel biomarker for mutant p53 could help pathologists assessing tumors during surgery

January 5, 2015

New discovery may make it easy for cancer surgeons to determine if a patient has a potentially lethal mutation.

Lloyd Trotman receives Pershing Square Sohn Prize for Cancer Research

May 5, 2014

Associate Professor Award encourages young investigators to take risks in search of a cure

Scientists develop powerful new animal model for metastatic prostate cancer

January 24, 2014

The new model, known as RapidCaP, reveals a cancer-gene ‘switch’ that drives metastasis

Long Island’s largest car show supports prostate cancer research at Cold Spring Harbor Laboratory

August 1, 2012

Of the 250,000 American men who will be diagnosed with prostate cancer this year, about 1% will develop lethal, metastatic disease.

CSHL Story archive for Tag: Lloyd Trotman