Reward and punishment take similar paths in the mouse brain 9/15/2020 One brain structure is involved with both positive and negative reinforcement types of learning. Read the story »
Brain receptor pulls open electrical gate like a puppet master 6/30/2020 When stimulated by a neurotransmitter or drug, the NMDA receptor pulls open an ion gate that allows ions to flow. Read the story »
New look at odd holes involved in taste, Alzheimer’s, asthma 1/27/2020 Large holes in our cells have been implicated in depression, Alzehimer’s disease, asthma, and even taste. Now, we know what two of these pores look like. Read the story »
How the brain balances pleasure and pain 12/31/2019 The brain balances signals that either excite or inhibit neurons and influence the motivation of an animal to seek a reward or avoid punishment. Read the story »
Interview with a neuroscientist 5/31/2019 CSHL Professor Bo Li’s lab studies the biology behind mental disorders. Learn more about how Li’s work is changing the way we think about mental health. Read the story »
How the brain hears and fears 12/5/2018 Researchers are studying how the brain reacts to sounds that it associates with fear, and how easy it is for the brain to learn and unlearn. Read the story »
How key brain receptor works in hostile conditions 5/9/2018 A structural variation enables a key brain receptor to function in a hostile environment Read the story »
Portrait of a Neuroscience Powerhouse 4/27/2018 A relatively small neuroscience group at CSHL is having an outsized impact on a dynamic and highly competitive field Read the story »
Detailed images of NMDA receptor show how zinc and a potential drug affect its function 12/1/2016 Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia. Read the story »
Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly 9/21/2016 Researchers have uncovered a neural circuit that processes evaluations and have succeeded in identifying its sources. Read the story »
Dealing with stress—to cope or to quit? 5/27/2014 Researchers identify neurons that determine whether an individual will be depressed or resilient Read the story »
Team demonstrates power of precision medicine in successful treatment of patient with disabling OCD 10/3/2013 Psychiatrist, geneticist, neurosurgeon & genome sequencers generate data on one patient, with powerful implications for care and counseling. Read the story »
X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus 10/19/2011 OPHN1 is found to be essential for mGluR-dependent longterm depression at synapses. Read the story »
New approaches to treatment of depression and bipolar disorder (Part 4 of 4) 6/29/2011 "New Approaches to Treatment of Depression and Bipolar Disorder" presented by Dr. Husseini Manji and Dr. Fritz Henn. Watch the video »