depression Archives - Cold Spring Harbor Laboratory

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How the brain hears and fears

December 5, 2018

Researchers are studying how the brain reacts to sounds that it associates with fear, and how easy it is for the brain to learn and unlearn.

How key brain receptor works in hostile conditions

May 9, 2018

A structural variation enables a key brain receptor to function in a hostile environment

Portrait of a Neuroscience Powerhouse

April 27, 2018

A relatively small neuroscience group at CSHL is having an outsized impact on a dynamic and highly competitive field

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

December 1, 2016

Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia.

Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly

September 21, 2016

Researchers have uncovered a neural circuit that processes evaluations and have succeeded in identifying its sources.

Dealing with stress—to cope or to quit?

May 27, 2014

Researchers identify neurons that determine whether an individual will be depressed or resilient

Team demonstrates power of precision medicine in successful treatment of patient with disabling OCD

October 3, 2013

Psychiatrist, geneticist, neurosurgeon & genome sequencers generate data on one patient, with powerful implications for care and counseling.

X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus

October 19, 2011

OPHN1 is found to be essential for mGluR-dependent longterm depression at synapses.

Video: CSHL Professor Fritz Henn discusses the challenge of tracing depression’s circuitry

February 24, 2011

CSHL Professor Fritz Henn, M.D., Ph.D., discusses in the accompanying video interview the challenge of finding the mechanisms underlying depression.

Neuroscientists find overlooked brain area is an important locus of depression

February 24, 2011

The lateral habenula is hyperactive in rat models of human depression

CSHL scientists identify elusive neuronal targets of deep brain stimulation

December 15, 2010

Study might provide new clues to designing better treatments for depression and other neuropsychiatric disorders

One experiment: Watching deep brain stimulation spur neuronal birth