CSHL Stories and Media archive for Tag: depression

Deciphering brain diseases with click chemistry

2/18/2025

Cold Spring Harbor Laboratory Professors John Moses and Hiro Furukawa speak at the CSHL Association’s 2025 Annual Meeting. Watch the video »

Ketamine: From club drug to antidepressant?

2/14/2025

CSHL Professor Hiro Furukawa proves the existence of a mysterious brain receptor known as GluN1-2B-2D and shows how it may interact with ketamine. Read the story »

This protein does “The Twist”

7/31/2024

CSHL Professor Hiro Furukawa has figured out how the NMDAR performs a key step in the brain’s cognitive dance. Read the story »

At the Lab Episode 2: Molecular puppetry

4/9/2024

CSHL neuroscientist Hiro Furukawa shows us a part of the brain that actually works like a puppet master. What could this mean for mental health? Listen to the podcast »

Mapping brain disorder therapeutics at work

7/29/2022

Dive into the 3D atomic structure of the NMDA receptor, important in several brain disorders, and see how it interacts with drugs that inhibit it. Watch the video »

Picky proteins: A new angle for brain disorder therapeutics

5/20/2022

Researchers have designed an antibody that may help treat brain disorders. See how it prevents neurons from malfunctioning. Watch the video »

Reward and punishment take similar paths in the mouse brain

9/15/2020

One brain structure is involved with both positive and negative reinforcement types of learning. Read the story »

Brain receptor pulls open electrical gate like a puppet master

6/30/2020

When stimulated by a neurotransmitter or drug, the NMDA receptor pulls open an ion gate that allows ions to flow. Read the story »

New look at odd holes involved in taste, Alzheimer’s, asthma

1/27/2020

Large holes in our cells have been implicated in depression, Alzehimer’s disease, asthma, and even taste. Now, we know what two of these pores look like. Read the story »

How the brain balances pleasure and pain

12/31/2019

The brain balances signals that either excite or inhibit neurons and influence the motivation of an animal to seek a reward or avoid punishment. Read the story »

Interview with a neuroscientist

5/31/2019

CSHL Professor Bo Li’s lab studies the biology behind mental disorders. Learn more about how Li’s work is changing the way we think about mental health. Read the story »

Brain, interrupted

Let us pick your brain with some neuroscience trivia. Take the quiz »

How the brain hears and fears

12/5/2018

Researchers are studying how the brain reacts to sounds that it associates with fear, and how easy it is for the brain to learn and unlearn. Read the story »

How key brain receptor works in hostile conditions

5/9/2018

A structural variation enables a key brain receptor to function in a hostile environment Read the story »

Portrait of a Neuroscience Powerhouse

4/27/2018

A relatively small neuroscience group at CSHL is having an outsized impact on a dynamic and highly competitive field Read the story »