In 2021, Cold Spring Harbor Laboratory (CSHL) received Charity Navigator’s highest possible 4-star rating for the twentieth time. This coveted designation indicates that the Laboratory adheres to best practices, executes its mission in a financially efficient way, exceeds industry standards, and outperforms most charities in its area of work. Charity Navigator’s 4-star rating demonstrates to the public that CSHL is a trustworthy steward of its funds, providing excellent transparency and governance practices.