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CSHL team identifies enzyme that is an important regulator of aggressive breast cancer development

6/30/2011

Researchers at Cold Spring Harbor Laboratory (CSHL) have identified an enzyme, PTPN23, that appears to be a significant regulator of breast cancer. Read the story »

CSHL structural biologists reveal novel drug binding site in NMDA receptor subunit

6/16/2011

Researchers create detailed blueprint of the allosteric site where phenylethanolamines bind to the receptor for future neurological treatments Read the story »

One experiment: A cellular battleground in lung cancer

6/11/2011

The lab of Assistant Professor Raffaella Sordella works on why certain tumors resistant to targeted therapy and what mechanisms lead to metastasis. Read the story »

Autism study validates importance of spontaneous causal mutations and sheds new light on gender skew

6/8/2011

A clinically extensive study of 1000 families with one autistic child and one unaffected sibling has validated a controversial theory. Read the story »

Study identifies stem cell-related changes that may contribute to age-related cognitive decline

5/5/2011

Age-related drop in new neurons may be due to “single use” or “disposable” nature of adult stem cells in the brain. Read the story »

CSHL structural biologists reveal molecular architecture of key NMDA receptor subunit

4/26/2011

Structure of GluN2D subunit when docked with certain neurotransmitters helps explain the receptor's slow deactivation. Read the story »

CSHL team perfects non-lethal way of switching off essential genes in mice

4/13/2011

CSHL researchers have developed a new, scalable approach based on RNA interference (RNAi) technology to temporarily turn off any essential gene. Read the story »

Researchers identify therapeutic target for liver cancer and a predictive biomarker of response

3/14/2011

The research points to a clear strategy for identifying the subset of liver cancer patients who might benefit from treatment with a therapeutic monocl Read the story »

With new method, CSHL team is able to infer how tumors evolve and spread

3/11/2011

Researchers find that cancerous tumors evolve in short, sudden bursts, rather than gradually. Read the story »

New method powerfully boosts efficiency of RNA interference (RNAi) in shutting down genes

2/24/2011

CSHL-led team finds an accurate, scalable way to identify potent RNAi triggers for biological studies and for RNA therapeutics. Read the story »

Video: CSHL Professor Fritz Henn discusses the challenge of tracing depression’s circuitry

2/24/2011

CSHL Professor Fritz Henn, M.D., Ph.D., discusses in the accompanying video interview the challenge of finding the mechanisms underlying depression. Read the story »

Neuroscientists find overlooked brain area is an important locus of depression

2/24/2011

The lateral habenula is hyperactive in rat models of human depression Read the story »

Study finds a stem cell origin of skin cancer and the genetic lesions that promote its malignancy

2/4/2011

Researchers have identified the genetic lesions occurring within these cells that spur them on to malignancy. Read the story »

CSHL is part of international team that sequences the ‘chocolate’ genome

1/14/2011

Researchers succeeded in producing a draft genome of a cacao tree variety whose beans yield the world’s finest chocolate. Read the story »

Podcast: CSHL Prof. Thomas Gingeras on new findings about the fly genome and why they are important

12/23/2010

New findings about the fly genome and why they are important Read the story »

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CSHL team identifies enzyme that is an important regulator of aggressive breast cancer development

CSHL team identifies enzyme that is an important regulator of aggressive breast cancer development

CSHL structural biologists reveal novel drug binding site in NMDA receptor subunit

One experiment: A cellular battleground in lung cancer

Autism study validates importance of spontaneous causal mutations and sheds new light on gender skew

Study identifies stem cell-related changes that may contribute to age-related cognitive decline

CSHL structural biologists reveal molecular architecture of key NMDA receptor subunit

CSHL team perfects non-lethal way of switching off essential genes in mice

Researchers identify therapeutic target for liver cancer and a predictive biomarker of response

With new method, CSHL team is able to infer how tumors evolve and spread

New method powerfully boosts efficiency of RNA interference (RNAi) in shutting down genes

Video: CSHL Professor Fritz Henn discusses the challenge of tracing depression’s circuitry

Neuroscientists find overlooked brain area is an important locus of depression

Study finds a stem cell origin of skin cancer and the genetic lesions that promote its malignancy

CSHL is part of international team that sequences the ‘chocolate’ genome

Podcast: CSHL Prof. Thomas Gingeras on new findings about the fly genome and why they are important

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