Research Archives - Cold Spring Harbor Laboratory

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One experiment: Observing cancer’s progress in a mouse prostate

March 14, 2019

Using a technique originally designed for mapping brains, two CSHL labs have worked together to image cancer progression in a mouse prostate.

New cell subtypes classified in mouse brain

March 12, 2019

To map a brain, an intuitive system for classifying neuron types is necessary. Now, a promising approach reveals new cell subtypes in the mouse brain.

Genetic ‘usual suspects’ identified in researchers’ new list

March 4, 2019

An exhaustive ranked list of “usual suspect” genes involved in disease may prove invaluable for future research and drug discovery.

Chandelier neuron requires ‘Velcro-like’ molecule to form connections

March 4, 2019

How do brain cells network? Researchers have discovered an essential ingredient that facilitates one type of neuron’s many neighborly connections.

Detailed new primate brain atlas could lead to disease insights

March 1, 2019

An international effort has mapped the marmoset brain at an unprecedented level of detail, which brings us closer to understanding the human brain.

What does sight mean to a cancer researcher?

February 26, 2019

Postdoc Leah Banks discusses vision’s role in cancer research, and how nearly losing her sight gave her a new perspective on her work.

How does math help us understand the brain?

January 31, 2019

An exploration of how computational neuroscientist Tatiana Engel uses math to understand how the brain makes decisions.

Targeting ‘hidden pocket’ for treatment of stroke and seizure

January 18, 2019

Researchers have identified a hidden molecular “pocket” in a special neuron receptor, which could lead to better treatments for stroke and seizures.

The year of CRISPR

December 26, 2018

A look at the various labs across CSHL that utilize CRISPR in their research, and the groundbreaking discoveries they help uncover.

How much are we learning? Natural selection is science’s best critic

December 17, 2018

Researchers determine that natural selection and our evolutionary history may be the best guides for future research.

Taking uncertainty out of cancer prognosis

December 11, 2018

CSHL Fellow Jason Sheltzer has analyzed nearly 20,000 cancer patient histories and genetic data to take the guesswork out of prognosis.

How the brain hears and fears

December 5, 2018

Researchers are studying how the brain reacts to sounds that it associates with fear, and how easy it is for the brain to learn and unlearn.

Inconspicuous protein key to deadly blood cancer

November 29, 2018

Associate Professor Chris Vakoc and his team find that an aggressive type of leukemia is heavily-dependent on a common protein.

Pancreatic cancer’s addiction could be its end

November 13, 2018

Researchers may have found a link between improper protein production and the spread of pancreatic cancer.

From many mice, unexpected genius

October 31, 2018

Researchers find that some individual mice are smarter than their fellow rodents, which can provide insights into decision-making.