The immune system, unleashed
Feature
Research
Cancer immunotherapy has a long and storied history, one that begins with a young woman suffering from a pain in her hand...
Newsstand Menu
Features
Search Stories
Nature’s masterpiece: the brain
Feature
Institutional
A message from President and CEO Dr. Bruce Stillman from the Spring 2018 Harbor Transcript on the innovative research happening at CSHL...
Bringing immune cells back into the cancer fight
Feature
Research
Doug Fearon used a mouse model to discover how pancreatic cancer hides from the immune system...
Portrait of a Neuroscience Powerhouse
Feature
Research
A relatively small neuroscience group at CSHL is having an outsized impact on a dynamic and highly competitive field...
Research profile: Robert Maki
Feature
Research
Straddling CSHL and Northwell Health gives Dr. Maki the perspective he needs to bring cancer research closer to the practice of treating patients...
The course to science stardom
Feature
Education
At least 10 CSHL Courses alumni have gone on to win a Nobel Prize, while others have become leaders of major scientific institutions...
One experiment: Twice the tomatoes
Feature
Research
Zachary Lippman’s team found a way to boost tomato yield by digging into the plant’s genome and fine-tuning its branching patterns....
The cancer answer that wasn’t
Feature
Research
We look at the "reproducibility crisis" in science, with a cancer researcher discovering something he didn't expect while experimenting with MELK...
One experiment: When cancer is hiding in plain sight
Feature
Research
Douglas Fearon's team is figuring out how to get immune cells to recognize—and kill—pancreatic cancer cells...
A lesson in class
Feature
Research
In this episode of Base Pairs, we discuss how genetic information is changing how we define important categories....
Research profile: Leemor Joshua-Tor
Feature
Research
A CSHL faculty member since 1995, a professor since 2005, Joshua-Tor is among the most distinguished members of the Laboratory community....
Next-gen cancer test
Feature
Research
Knowing that cancers become lethal when they spread, investigators at Cold Spring Harbor Laboratory seek a way of detecting tumors much earlier ...
One experiment: A beautiful brain, neuron by neuron
Feature
Research
Associate Professor Pavel Osten and colleagues discovered using their qBrain method is discerned by probing hidden relations among the dots....
Double Helix Medals dinner
Feature
Institutional
The 2017 Double Helix Medals were presented to Tom Brokaw and Helen Ann and Charles Dolan....
Big decisions
Feature
Research
David Micklos of the DNA Learning Center, and Miriam Rich, a research scholar, talk about the big issues of eugenics....
One experiment: Bacteria-trapping DNA webs are repurposed by cancer cells
Feature
Research
Associate Professor Mikala Egeblad discovers that neutrophil extracellular traps (NETs) help cancer by creating holes in the tissue....
Good genes, bad science
Feature
Research
On this episode, Base Pairs looks into the eugenics movement, including the record kept in CSHL....
Do neuroscientists need to switch gears to understand how brains make choices?
Feature
Research
Associate Professor Anne Churchland, co-founder the IBL along with Professor Tony Zador, explains how it could help solve a problem in neuroscience....
What Silicon Valley and biology research share
Feature
Research
Further discussion with Associate Professor Gurinder "Mickey" Atwal about the need for more math and physics in biology....
Biology, behind the screens
Feature
Research
Associate Professor Gurinder "Mickey" Atwal talks about the essential mystery at the center of quantitative biology....
Tomato baby and its family
Feature
Research
This episode of Base Pairs talks to Associate Professor Zachary Lippman about all the weird mutations that naturally occur in plants....
CRISPR vs. climate change
Feature
Research
This episode of Base Pairs looks at the issues climate change may bring to agriculture and how CRISPR can help overcome them....
Redefining biologists, redefining genes
Feature
Research
Drs. Molly Hammell and Thomas Gingeras talk about redefining what a biologist is and what genes are....
Dark matter of the genome, part 2
Feature
Research
This episode of Base Pairs deals with the myth of "junk DNA" and why scientists are interested in non-coding portions of the genome....
Dark matter of the genome, part 1
Feature
Research
This episode of Base Pairs digs into "dark matter" a type of genetic information that could help scientists better understand diseases like...
Molecules and a mission
Feature
Research
A special bonus episode of Base Pairs offering an explanation of why the name "Base Pairs" was chosen...
The brain atlas
Feature
Research
This episode of BasePairs looks at the problems of neuropsychiatric drug discovery, and the method by which they may soon be resolved....
One experiment: A drug for SMA visibly repairs defective cells
Feature
Research
Professor Adrian Krainer develops a treatment for spinal muscular atrophy, the leading genetic cause of infant death....
When antioxidants are pro-cancer
Feature
Research
For Pancreatic Cancer Awareness Month, Base Pairs looks at the science of antioxidants and cancer....
“Sink or swim”
Feature
Research
This episode of Base Pairs follows Professor Adrian Krainer and his experience as the first CSHL fellow....
The people problem
Feature
Research
This episode of Base Pairs looks at the rising population, plant biology, and the future of food....
Non-modern family
Feature
Education Research
This episode on Base Pairs explores how genetic information to better understand human history....
Corn controversy
Feature
Research
This episode of Base Pairs covers the contentious genetics and history of America’s corn production....
One experiment: How the breast “remembers” a first pregnancy
Feature
Research
Professor Greg Hannon and his team, including Assistant Professor Camila dos Santos, learn more about breast cells and tissue....
From phages to faces
Feature
Research
In the pilot episode of Base Pairs, two stories of DNA research that show how far the field has come...
One experiment: Cellular highways carry anti-cancer cargoes
Feature
Research
The gene called PTEN is one of the most important of the body’s natural tumor suppressors....
One experiment: McClintock’s historic discovery
Feature
Research
Four decades after this photo was taken, a Nobel Prize was awarded to McClintock, acknowledging her discovery that genetic material is not fixed...
One experiment: Sometimes our cells express only one gene copy. Why?
Feature
Research
Professor David L. Spector and team discover some monoallelically expressed genes encoded extra RNA, even though they are missing their other gene....
