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Research reveals “exquisite selectivity” of neuronal wiring in the cerebral cortex

8/21/2017

Inhibitory chandelier cells receive and transmit information from different ensembles of excitatory cells in their cortical neighborhood. Read the story »

Biology, behind the screens

8/15/2017

Associate Professor Gurinder "Mickey" Atwal talks about the essential mystery at the center of quantitative biology. Read the story »

Structural view suggests RNAi machinery multiplies its efficiency in repressing gene expression

8/3/2017

Leemor Joshua-Tor publishes atomic-resolution pictures and an analysis of RNAi machinery Read the story »

Long-sought mechanism of metastasis is discovered in pancreatic cancer

7/27/2017

An epigenetic factor reprograms gene enhancers, enabling cancer cells to “remember” an earlier developmental state and causing metastasis. Read the story »

Team traces masculinization in mice to estrogen receptor in inhibitory neurons

7/20/2017

CSHL researchers discover when ERα receptors are deleted in the brains of male mice, they do not exhibit typical "masculine" behaviors during puberty. Read the story »

Library of CRISPR targeting sequences increases power and accuracy of the gene-editing method

7/20/2017

New library of RNA sequences that can be used by researchers to direct the CRISPR-cas9 complex to cut DNA with unprecedented precision. Read the story »

Tomato baby and its family

7/14/2017

This episode of Base Pairs talks to Associate Professor Zachary Lippman about all the weird mutations that naturally occur in plants. Read the story »

Freeze-frames of enzymes in action have implications for a new cancer treatment concept

7/3/2017

TUTase enzymes interact with let-7, a regulator of development; targeting them could help control certain cancers. Read the story »

Newly identified small RNA fragments defend the genome when it’s ‘naked’

6/29/2017

Fragments snipped from tRNAs protect embryonic stem cells while they’re being epigenetically reprogrammed. Read the story »

New statistical method finds shared ancestral gene variants involved in autism’s cause

6/21/2017

Researchers find children with autism are genetically more like other autistic children than their unaffected siblings. Read the story »

CRISPR vs. climate change

6/15/2017

This episode of Base Pairs looks at the issues climate change may bring to agriculture and how CRISPR can help overcome them. Read the story »

Detailed new ‘reference’ genome for maize shows the plant has deep resources for continued adaptation

6/12/2017

A new, much more detailed reference genome for maize, or corn, as it is called in the U.S., provides new insight into the crop. Read the story »

A protein that stem cells require could be a target in killing breast cancer cells

6/1/2017

Cancer cells, like stem cells, have the ability to multiply indefinitely but epigenetic factor BPTF may be a shared weakness. Read the story »

Fine-tuning dosage of mutant genes unleashes long-trapped yield potential in tomato plants

5/18/2017

Understanding gene interactions can enable breeders to break existing productivity barriers in agriculture. Read the story »

Redefining biologists, redefining genes

5/16/2017

Drs. Molly Hammell and Thomas Gingeras talk about redefining what a biologist is and what genes are. Read the story »

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Research reveals “exquisite selectivity” of neuronal wiring in the cerebral cortex

Research reveals “exquisite selectivity” of neuronal wiring in the cerebral cortex

Biology, behind the screens

Structural view suggests RNAi machinery multiplies its efficiency in repressing gene expression

Long-sought mechanism of metastasis is discovered in pancreatic cancer

Team traces masculinization in mice to estrogen receptor in inhibitory neurons

Library of CRISPR targeting sequences increases power and accuracy of the gene-editing method

Tomato baby and its family

Freeze-frames of enzymes in action have implications for a new cancer treatment concept

Newly identified small RNA fragments defend the genome when it’s ‘naked’

New statistical method finds shared ancestral gene variants involved in autism’s cause

CRISPR vs. climate change

Detailed new ‘reference’ genome for maize shows the plant has deep resources for continued adaptation

A protein that stem cells require could be a target in killing breast cancer cells

Fine-tuning dosage of mutant genes unleashes long-trapped yield potential in tomato plants

Redefining biologists, redefining genes

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