Detailed images of NMDA receptor show how zinc and a potential drug affect its function 12/1/2016 Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia. Read the story »
Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly 9/21/2016 Researchers have uncovered a neural circuit that processes evaluations and have succeeded in identifying its sources. Read the story »
Innovative tools will shed clarifying light on inhibitory neurons 9/21/2016 Researchers at Cold Spring Harbor Laboratory created a set of tools that combine genetic markers and virus particles to target GABA cell types. Read the story »
Our brain uses statistics to calculate confidence, make decisions 5/4/2016 The brain produces feelings of confidence that inform decisions the same way statistics pulls patterns out of noisy data. Read the story »
First structural views of the NMDA receptor in action will aid drug development 5/2/2016 Structural biologists obtained snapshots of the activation of an important type of brain-cell receptor. Read the story »
CSHL scientists Bo Li and Je Lee win HFSP Research Grant awards 4/12/2016 Associate Professor Bo Li and Assistant Professor Je Lee, are among 25 teams that have won Human Frontier Science Program Research Program Grants Read the story »
Discovery of a new X-linked intellectual disability syndrome is aided by web communication tools 12/3/2015 A geneticist uses social media and online tools to help confirm, document and describe in precise clinical detail a new genetic syndrome in young Read the story »
Surprised? Cholinergic neurons send brain-wide broadcasts enabling us to learn from the unexpected 8/25/2015 Researchers find dedicated neurons that rapidly informing multiple subregions in the brain of any surprising rewards or punishments. Read the story »
Drs. Kepecs and Li honored with 2015 NARSAD Independent Investigator grant awards 5/12/2015 Dr. Kepecs and Dr. Li received two-year grants to fund their important research. Read the story »
Scientists discover important communication mechanism between two brain areas implicated in schizophrenia 4/7/2015 Researchers discover an inhibitory connection between certain brain areas that can control the timing of information flow to the prefrontal cortex Read the story »
A new brain circuit that controls fear is identified 1/19/2015 Researchers discover a pathway in that mouse brain that regulates fear memory and behavior Read the story »
Imaging method linking brainwide cell activation & behavior shows what it means for mice to have sex in mind 1/5/2015 Automated method detects activity of neurons during specific behaviors, brainwide, at cellular resolution Read the story »
Neuronal circuits filter out distractions in the brain 12/15/2014 Scientists identify a neural pathway that controls attention, with implications for psychiatric disorders Read the story »
4 CSHL scientists will contribute to President’s BRAIN Initiative under new NIH grants 9/30/2014 Four scientists at Cold Spring Harbor Laboratory (CSHL) will perform research in President Obama’s BRAIN Initiative under two new CSHL grants Read the story »
A shift in the code: New method reveals hidden genetic landscape 8/18/2014 Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD Read the story »