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Alternative pathway of microRNA generation is uncovered

Alternative pathway of microRNA generation is uncovered

4/28/2010

A unique class of proteins called Argonautes help microRNAs control gene expression in organisms ranging from bacteria all the way up to humans. Read the story »

CSHL scientists discover how a tumor suppressor gene induces cellular senescence and staves off cancer

4/13/2010

The tumor suppressor Retinoblastoma represses DNA replication genes during senescence. Read the story »

CSHL neuroscientists reverse Alzheimer’s-like memory loss by targeting signaling protein in fruitflies

3/29/2010

B-amyloid peptides are known to alter a slew of cellular signaling proteins such as PI3 kinase. Read the story »

Single gene dramatically boosts yield and sweetness in tomato hybrids, joint CSHL-Israeli study reports

3/29/2010

Scientists find the first example of a single gene that causes hybrid vigor. Read the story »

CSHL-Mexican team coaxes sexually reproducing plant to brink of asexual reproduction

3/7/2010

Argonaute 9 inhibits asexual reproduction, apparently by silencing transposons. Read the story »

populations of neurons in the antennal lobe of the fly

CSHL neuroscientist discovers protein that regulates forgetting of short-term memories

2/18/2010

Fruit fly experiments show inhibiting and elevating Rac activity slows and speeds erasure. Read the story »

expression patterns of pyruvate kinase M1/M2 isoforms

CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth

1/22/2010

Altered metabolism in cancer cells is most critically mediated by a protein called PK-M2. Read the story »

Joubert Syndrome 2 (JBTS2) in Ashkenazi Jews

Genetic cause of devastating disorder is rapidly discovered by CSHL scientists using next-gen sequencing

1/13/2010

The mutated gene, which causes Joubert Syndrome, is carried by 1 in 92 Ashkenazi Jews Read the story »

CSHL scientists uncover role of protein critical for activating DNA replication

1/7/2010

An inhibitory activity within the Mcm4 NSD is responsible for the dependency of cells on DDK for viability. Read the story »

CSHL study shows that protein linked to leukemia “bookmarks” highly active genes during cell division

1/5/2010

Each cell inherits genes from its parent as well as epigenetic information—what amounts to an instruction manual that specifies which genes Read the story »

Mystery solved: Facial cancer decimating Tasmanian devils likely began in cells protecting nerve fibers

12/31/2009

CSHL-led research uncovers diagnostic marker and blazes trail toward treatments. Read the story »

One experiment: The auditory cortex responding to sound

12/1/2009

Anthony Zador and colleagues solve the mystery of how the brain understands sound by tagging neuronal groups. Read the story »

Reference genome of maize, America’s most important crop, is published by team co-led by CSHL scientists

11/19/2009

Complex sequence and "HapMap" shed light on maize's "wonderful diversity" could help future efforts to adapt the plant to a warming climate. Read the story »

CSHL team solves molecular structure of NMDA receptor subunit that could be target for drugs against neurological diseases

11/13/2009

A domain of the NR2B subunit of the NMDA receptor is mapped in exquisite detail. Read the story »

CSHL study shows that malignant tumors can be shut down after all

11/9/2009

Aggressive tumors lacking p53 protein stop dead in their tracks when p53’s sister protein—TAp63—steps in. Read the story »

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Alternative pathway of microRNA generation is uncovered

Alternative pathway of microRNA generation is uncovered

CSHL scientists discover how a tumor suppressor gene induces cellular senescence and staves off cancer

CSHL neuroscientists reverse Alzheimer’s-like memory loss by targeting signaling protein in fruitflies

Single gene dramatically boosts yield and sweetness in tomato hybrids, joint CSHL-Israeli study reports

CSHL-Mexican team coaxes sexually reproducing plant to brink of asexual reproduction

CSHL neuroscientist discovers protein that regulates forgetting of short-term memories

CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth

Genetic cause of devastating disorder is rapidly discovered by CSHL scientists using next-gen sequencing

CSHL scientists uncover role of protein critical for activating DNA replication

CSHL study shows that protein linked to leukemia “bookmarks” highly active genes during cell division

Mystery solved: Facial cancer decimating Tasmanian devils likely began in cells protecting nerve fibers

One experiment: The auditory cortex responding to sound

Reference genome of maize, America’s most important crop, is published by team co-led by CSHL scientists

CSHL team solves molecular structure of NMDA receptor subunit that could be target for drugs against neurological diseases

CSHL study shows that malignant tumors can be shut down after all

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