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CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth

expression patterns of pyruvate kinase M1/M2 isoforms

CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth

1/22/2010

Altered metabolism in cancer cells is most critically mediated by a protein called PK-M2. Read the story »

Joubert Syndrome 2 (JBTS2) in Ashkenazi Jews

Genetic cause of devastating disorder is rapidly discovered by CSHL scientists using next-gen sequencing

1/13/2010

The mutated gene, which causes Joubert Syndrome, is carried by 1 in 92 Ashkenazi Jews Read the story »

CSHL scientists uncover role of protein critical for activating DNA replication

1/7/2010

An inhibitory activity within the Mcm4 NSD is responsible for the dependency of cells on DDK for viability. Read the story »

CSHL study shows that protein linked to leukemia “bookmarks” highly active genes during cell division

1/5/2010

Each cell inherits genes from its parent as well as epigenetic information—what amounts to an instruction manual that specifies which genes Read the story »

Mystery solved: Facial cancer decimating Tasmanian devils likely began in cells protecting nerve fibers

12/31/2009

CSHL-led research uncovers diagnostic marker and blazes trail toward treatments. Read the story »

One experiment: The auditory cortex responding to sound

12/1/2009

Anthony Zador and colleagues solve the mystery of how the brain understands sound by tagging neuronal groups. Read the story »

Reference genome of maize, America’s most important crop, is published by team co-led by CSHL scientists

11/19/2009

Complex sequence and "HapMap" shed light on maize's "wonderful diversity" could help future efforts to adapt the plant to a warming climate. Read the story »

CSHL team solves molecular structure of NMDA receptor subunit that could be target for drugs against neurological diseases

11/13/2009

A domain of the NR2B subunit of the NMDA receptor is mapped in exquisite detail. Read the story »

CSHL study shows that malignant tumors can be shut down after all

11/9/2009

Aggressive tumors lacking p53 protein stop dead in their tracks when p53’s sister protein—TAp63—steps in. Read the story »

Researchers identify drug candidate for treating spinal muscular atrophy

11/4/2009

A chemical cousin of the common antibiotic tetracycline might be useful in treating spinal muscular atrophy (SMA) Read the story »

CSHL-led team discovers rare mutation dramatically increasing schizophrenia risk

10/26/2009

Gene copy number variations of the same region, 16p11.2, are already linked to autism. Read the story »

Using RNAi-based technique, CSHL scientists find new tumor suppressor genes in lymphoma

10/9/2009

Discovery reveals gene activity networks that let tumors thrive and suggests new modes of therapy. Read the story »

CSHL scientists identify protein that enhances long-term memory by controlling rest periods

10/1/2009

Discovery could lead to treatments for learning and memory deficits, particularly Noonan’s syndrome Read the story »

CSHL scientists develop new method to detect copy number variants using DNA sequencing technologies

8/25/2009

The new technique can detect key genetic variations overlooked by current methods. Read the story »

Short- and long-term memories depend on the same gene, acting in different neuronal circuits, CSHL study finds

8/14/2009

Activity of the rutabaga gene determines much of a fruit fly’s ability to learn and remember Read the story »

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CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth

CSHL study identifies potential way to reverse cancer cell metabolism and tumor growth

Genetic cause of devastating disorder is rapidly discovered by CSHL scientists using next-gen sequencing

CSHL scientists uncover role of protein critical for activating DNA replication

CSHL study shows that protein linked to leukemia “bookmarks” highly active genes during cell division

Mystery solved: Facial cancer decimating Tasmanian devils likely began in cells protecting nerve fibers

One experiment: The auditory cortex responding to sound

Reference genome of maize, America’s most important crop, is published by team co-led by CSHL scientists

CSHL team solves molecular structure of NMDA receptor subunit that could be target for drugs against neurological diseases

CSHL study shows that malignant tumors can be shut down after all

Researchers identify drug candidate for treating spinal muscular atrophy

CSHL-led team discovers rare mutation dramatically increasing schizophrenia risk

Using RNAi-based technique, CSHL scientists find new tumor suppressor genes in lymphoma

CSHL scientists identify protein that enhances long-term memory by controlling rest periods

CSHL scientists develop new method to detect copy number variants using DNA sequencing technologies

Short- and long-term memories depend on the same gene, acting in different neuronal circuits, CSHL study finds

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