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GABA signaling prunes back copious ‘provisional’ synapses during neural circuit assembly

GABA signaling prunes back copious ‘provisional’ synapses during neural circuit assembly

1/3/2012

Researchers discover the process of pruning incompatible preliminary synaptic connections. Read the story »

Study uncovers a molecular “maturation clock” that modulates branching architecture in tomato plants

12/22/2011

The secret to pushing tomato plants to produce more fruit might not lie in an extra dose of Miracle-Gro Read the story »

First comprehensive DNA study of mast cell leukemia uncovers clues that could improve therapy

12/16/2011

Sequencing a cancer patient’s “exome” reveals mutations critical for improving diagnostic power and targeted therapy. Read the story »

New York Plant Genomics Consortium maps evolutionary relationships, gene functions for 150 species

12/16/2011

The New York Plant Genomics Consortium have developed a genome “tree of life” that is largest yet for seed plants. Read the story »

Unexpected signaling role for foul-smelling hydrogen sulfide in cell response to protein misfolding

12/13/2011

Hydrogen sulfide plays an important role in the regulation of a signaling pathway implicated in biological malfunctions linked to Alzheimer’s. Read the story »

CSHL team solves a protein complex’s molecular structure to explain its role in gene silencing

11/14/2011

Researchers discover new details of how the RNA-Induced Initiation of Transcriptional gene Silencing (RITS) complex contributes to gene silencing Read the story »

Study reveals details of alternative splicing circuitry that promotes cancer’s Warburg effect

11/2/2011

Dr. Krainer and his team discovered details of the molecular events that trigger the production of the enzyme that drives the Warburg effect. Read the story »

X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus

10/19/2011

OPHN1 is found to be essential for mGluR-dependent longterm depression at synapses. Read the story »

Study reveals new role for RNA interference during chromosomal replication

10/17/2011

A new study in Nature by CSHL Professor Rob Martienssen and his group describes a new role for RNAi during chromosomal replication, one that allows th Read the story »

Study shows how “bookmarking” genes before cell division accelerates their subsequent reactivation

10/11/2011

Researchers discover how "bookmarking" a gene pre-split accelerates its reactivation after the division. Read the story »

Antisense therapy delivers long-term correction of severe spinal muscular atrophy in mice

10/5/2011

Researchers report surprising results that suggest that spinal muscular atrophy might not exclusively affect the motor neurons in the spinal cord. Read the story »

CSHL team finds evidence for the genetic basis of autism

10/3/2011

Scientists find evidence that inheriting fewer copies of these genes leads to features resembling those used to diagnose children with autism. Read the story »

Nicholas Tonks Chasm of Doom active site

Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity

9/29/2011

Novel drugs find ways around obstacles of the pathway within cells that regulates the response to insulin. Read the story »

Research reveals how dynamic changes in methylation can determine cell fate

9/26/2011

Scientists have uncovered intriguing new evidence helping to explain one of the ways in which a stem cell’s fate can be determined. Read the story »

One experiment: Pinpointing inhibitory neurons across the mouse brain

9/21/2011

Huang lab studies GABA neurons, which inhibit brain signals. to better understand their mechanisms and how they can be used for treatment purposes. Read the story »

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GABA signaling prunes back copious ‘provisional’ synapses during neural circuit assembly

GABA signaling prunes back copious ‘provisional’ synapses during neural circuit assembly

Study uncovers a molecular “maturation clock” that modulates branching architecture in tomato plants

First comprehensive DNA study of mast cell leukemia uncovers clues that could improve therapy

New York Plant Genomics Consortium maps evolutionary relationships, gene functions for 150 species

Unexpected signaling role for foul-smelling hydrogen sulfide in cell response to protein misfolding

CSHL team solves a protein complex’s molecular structure to explain its role in gene silencing

Study reveals details of alternative splicing circuitry that promotes cancer’s Warburg effect

X-linked mental retardation protein is found to mediate synaptic plasticity in hippocampus

Study reveals new role for RNA interference during chromosomal replication

Study shows how “bookmarking” genes before cell division accelerates their subsequent reactivation

Antisense therapy delivers long-term correction of severe spinal muscular atrophy in mice

CSHL team finds evidence for the genetic basis of autism

Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity

Research reveals how dynamic changes in methylation can determine cell fate

One experiment: Pinpointing inhibitory neurons across the mouse brain

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