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Postdoctoral Positions

Why come to CSHL for your Postdoc?

CSHL has long been recognized as a place for nurturing young scientists, with postdoctoral researchers being integral parts of the discovery process. CSHL’s relatively small size—around 55 labs—combined with its collaborative and multidisciplinary research programs creates a unique environment for the next step in your scientific career.

Current Open Postdoc Positions

Breast Cancer researchers at CSHL

Scientific excellence

CSHL is one of the leading biomedical research institutions in the U.S., with research in five main areas: cancer biology, neuroscience, plant biology, quantitative biology, and genomics. In addition, CSHL is an NCI Cancer Center dedicated to studying the fundamental biology of human cancer, and translating these breakthroughs from bench to bedside. Across the entire community at CSHL, there is a distinct spirit of scientific pursuit and interactions, resulting in innovative and productive collaborations.

light-sheet microscopy

Resources

CSHL’s postdocs have access to all the scientific resources available on campus. This includes Core Facilities that feature the latest technology and expertise. These Cores are fast, reliable, and cost-effective, offering in-house support that can be customized and collaborative to spur the development of novel technological applications and creative research.

Career development

Your training as a postdoc at CSHL extends beyond the bench. There is a suite of Career Development offerings, including short courses, workshops, lectures, and seminars that provide opportunities for scientific enrichment and professional development. In addition, there are programs in career exploration and opportunities to develop skills such as leadership, mentoring and communication.

photo of CSHL Meetings & Courses

Extramural meetings & courses

CSHL’s extensive Meetings & Courses Program brings top scientists from around the world to campus to present and discuss the latest research in a wide variety of scientific. This is great opportunity to network and meet with colleagues.

photo of Jones building with meeting participants

A vibrant community

The Laboratory offers a collegial and collaborative work environment as well as a beautiful location just a short train ride from New York City. CSHL has several postdoctoral and student-led groups, including an active Postdoctoral Liaison Committee (PDLC), whose purpose is to represent the interests of and advocate for the CSHL postdoctoral community.

photo of the exterior CSHL Day Care Center building
Image: Jeff Goldberg/ESTO

Onsite child care center

CSHL has an excellent and affordable, licensed, on-site childcare center that serves children from six weeks to six years old.

aerial photo of the Cold Spring Harbor Laboratory campus

Compensation & benefits

CSHL offers an excellent comprehensive benefits program, an onsite Wellness Center, a Fitness Center, subsidized dining experiences and complimentary shuttle service. The CSHL Housing Office can help postdocs find affordable housing, either through a shared-housing program, or through local realtors. In addition, all postdoctoral fellows are eligible for relocation reimbursement and a family allowance. The Postdoctoral Fellows are compensated based on their years of experience. The salaries can be accessed at “Postdoctoral Stipend Schedule.” (PDF)

Postdoctoral Fellow opportunities

Computational Postdoctoral FellowCowley Lab – 03327-R

We are looking for a computational postdoc broadly interested in using machine learning approaches to answer scientific questions about the brain. We focus on designing closed-loop methods for systems neuroscience as well as building explainable computational models of neural responses and behavior. An important component of our work is to build tight-knit collaborations with experimental neuroscientists—collecting data and building models in tandem. A long-term goal is to identify and understand the step-by-step computations in the brain.

Postdoctoral Fellow – Gholami Lab – 00241

A position is available for a postdoctoral researcher with a strong background in cancer biology and immunology. This postdoctoral fellow will be working under the directions of Dr. Gholami (an Associate Professor and surgeon scientist at Northwell Health). The project will be focused on translational research studying the tumor microenvironment of colorectal cancer, with the overall goal of finding novel targeted and immune-augmenting combination therapies. The aims of the Project include developing and testing new treatment strategies, characterizing interactions between tumor and immune microenvironment, and elucidate mechanisms of response/resistance to therapies.

Postdoctoral FellowEgeblad Lab – 00241

A position is available for a postdoctoral researcher with a strong background in cancer biology and immunology. This postdoctoral fellow will be working under the directions of Dr. Gholami (an Associate Professor and surgeon scientist at Northwell Health) within the lab of Mikala Egeblad. The project will be focused on translational research studying the tumor microenvironment of colorectal cancer, with the overall goal of finding novel targeted and immune-augmenting combination therapies. The aims of the Project include developing and testing new treatment strategies, characterizing interactions between tumor and immune microenvironment, and elucidate mechanisms of response/resistance to therapies.

Postdoctoral FellowFurukawa Lab – 03088-R

The Furukawa lab has NIH-funded postdoctoral fellow/associate positions available for scientists interested in solving questions in neurobiology and neuro-cancer-immunology by implementing a dynamic range of techniques including structural biology (cryo-EM, x-ray crystallography, molecular dynamics) together with electrophysiology (patch-clamp, slice physiology, lipid bilayer), protein engineering, chemical biology, mouse model, cellular imaging, and cancer mouse model. underlying cognitive functions.

Postdoctoral FellowJanowitz Lab – 02988-R

The Janowitz Laboratory at CSHL is seeking a highly motivated, creative, and interactive postdoctoral researcher with strong experimental and analytical skills to contribute to research on the connectivity of the host response to cancer. We employ pre-clinical and clinical research to develop and test new treatment strategies and to discover fundamental biological interactions between tumors and host organ systems.

Joint Postdoctoral FellowBorniger Lab, Janowitz Lab, Lukey Lab – 03167-R

Together, the Borniger, Lukey, and Janowitz laboratory at Cold Spring Harbor Laboratory (CSHL) offer a unique opportunity for a highly motivated and creative postdoctoral researcher, with strong experimental and analytical skills, to investigate the reciprocal interaction of sleep and cancer progression. You will become part of a multidisciplinary team of basic researchers and clinicians studying tumor-host interactions, using integrative techniques from neuroscience, endocrinology, metabolomics, and immunology to dissect the mechanisms connecting sleep disruption with aberrant metabolic and immune responses during cancer progression.

Postdoctoral FellowJoshua-Tor lab – 03123-R

We are currently seeking innovative, inventive, and self-driven Postdoctoral Associates within the lab of Dr. Leemor Joshua-Tor at Cold Spring Harbor Laboratory. The Joshua-Tor lab studies the structure and mechanism of gene silencing pathways as well as DNA replication. To get a complete understanding of how these processes, the team employs structural, biochemical, biophysical and molecular biology approaches to study how key proteins work at the molecular level. More information can be found on their website.

Computational Postdoctoral FellowKoulakov Lab – 03057-R

Cold Spring Harbor Laboratory is looking for outstanding candidates to fill postdoctoral positions in theoretical neuroscience. The position is open under specific projects as well as general research involving the application of methods from theoretical physics, mathematics, and machine learning with the goal to understand the brain function.

Postdoctoral FellowshipsZhang Lab – 03248-R

Dr. Lingbo Zhang’s Laboratory at Cold Spring Harbor Laboratory (CSHL) is part of a $75 million Center for Therapeutics Research at CSHL. There are multiple fully funded postdoctoral fellowships available in the Zhang Laboratory to investigate roles of nervous system activities and micronutrients in regulating hematologic cancers and to develop novel therapeutic strategies for these diseases.

Postdoctoral FellowMartienssen Lab – 03249-R

The Martienssen laboratory at Cold Spring Harbor has an opening for a postdoctoral fellow to study the mechanisms of epigenetic inheritance in fission yeast and mammalian cells, recently funded by the National Institutes of Health. RNA interference impacts inheritance and genome stability by silencing of repeats, as well as by non-canonical means, and successful applicants will explore the role of epigenetic modifications, phase separation and transcription-replication conflict in different developmental and cell cycle contexts. State-of-the art equipment and facilities are available both within the lab and in outstanding shared facilities.

Computational Post DocMcCandlish Lab – 02798-R & 02802-R

Research in the McCandlish laboratory is focused on the analysis of high-throughput mutagenesis data, with the goal of accurately predicting the phenotypic, health, and evolutionary consequences of both single and multiple mutations in protein coding and regulatory sequences.  The group has a particular emphasis on understanding complex genetic interactions and the structure of the genotype-phenotype map.

Computational Post DocSiepel Lab – 02744-R

A postdoctoral position in COMPUTATIONAL GENOMICS is available in Dr. Adam Siepel’s research group at the Simons Center for Quantitative Biology (SCQB), Cold Spring Harbor Laboratory.

The Siepel Group specializes in the development of probabilistic models and algorithms for inference, machine-learning methods, and applications in large-scale genomic data analysis. Of particular interest is research relevant to existing NIH-supported projects in:

  1. EVOLUTIONARY GENOMICS of humans and other mammals, including inference of ancestral recombination graphs, detection of selective sweeps, comparative genomics of bats, inference of distributions of fitness effects and quantification of genetic load from linked deleterious alleles; and
  2. TRANSCRIPTIONAL REGULATION in mammals, including quantification of initiation and pause-release rates from nascent RNA sequencing data, characterization of elongation rates, and evolutionary analysis of transcriptional regulation across primates and other mammals.

Postdoctoral FellowVan Aelst Lab – 02796-R

The main focus of research will be to study the roles of genes associated with human diseases in the development and function of neural circuits, using molecular, genetic and viral engineering, optogenetics, imaging, electrophysiology, and behavior analysis.

Postdoctoral FellowWigler Lab – 02822-R

The Wigler and Levy research group are seeking a Computational Post Doc that will have a key role in a multi-disciplinary team of wet-bench and computational researchers working to revolutionize cancer detection and treatment by developing novel genomic technologies. We are re-envisioning the tools of genetics research by coupling innovation at the bench with novel computational methods. We have developed methods for inexpensive copy number (SMASH), generating long reads from short-read sequencers (muSeq), encapsulation of cells in acrylamide gel (BAG-seq), sensitive detection of cancer genomes (MASQ), and most recently mutational sequencing for short tandem repeats (muSTR). Applicants may review our most recent publications at http://wigserv2.cshl.edu/doku.php?id=publications.

Postdoctoral FellowYeh Lab – 02869-R

The Yeh Laboratory at CSHL Cancer Center is seeking for a qualified postdoctoral fellow passionate about biotherapeutics discovery and engineering. The Yeh Lab is a highly-collaborative environment with state-of-the-art facilities and expertise in biotherapeutics engineering and chemical biology.

Postdoctoral Fellow – International Brain LaboratoryZador Lab – 03269-R

The Zador lab has an opening for a postdoctoral fellow in neuroscience who will be part of the International Brain Laboratory (IBL). The IBL is a large-scale international collaboration in brain research, which combines the efforts of approximately 50 scientists in 22 laboratories toward understanding the brain-wide basis of a mouse visual decision-making task. The overall goal of this postdoc’s project will be to relate single neuron connectivity, gene expression and neural activity in the context of in the context of the IBL behavior, to better understand the contributions of different neuronal types to the IBL task. Specifically, the project will involve combining electrophysiological and imaging approaches (widefield and two-photon, including a mesoscope) with new approaches for high-throughput circuit/genomic approaches (including BARseq and MAPseq) developed in the Zador lab.