How the brain balances pleasure and pain
The brain balances signals that either excite or inhibit neurons and influence the motivation of an animal to seek a reward or avoid punishment. Read the story »
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Finally, machine learning interprets gene regulation clearly
Machine learning and a new kind of easily-interpretable artificial neural network is helping scientists make sense of crucial gene regulation. Read the story »
A new tomato ideal for urban gardens and even outer space
Researchers used CRISPR gene editing to optimize tomatoes for urban agriculture, preparing them for the city rooftops and possibly space missions. Read the story »
Mikala Egeblad wins Marks Foundation ASPIRE Award
Associate Professor Mikala Egeblad received the ASPIRE award to fund research understanding the relationship between stress and metastasis. Read the story »
Shifting the balance of growth vs. defense boosts crop yield
Researchers found that a specific gene in maize balances both growth of the plant and its immunity. Read the story »
Saket Navlakha taps the power of biology and computers
Associate Professor Saket Navlakha is bringing ideas about “algorithms in nature” to the Simons Center for Quantitative Biology. Read the story »
Ann Lin named in Forbes 30 Under 30 list for 2020
Ann Lin, a former intern in CSHL Fellow Jason Sheltzer’s lab, has been named a top entrepreneur on the Forbes 30 Under 30 list. Read the story »
DNA Learning Center takes New York
DNA Learning Center is expanding its educational reach into the greater New York area through the opening of two new centers. Read the story »
A new DNA Learning Center at Regeneron
Regeneron Pharmaceuticals and CSHL partner to open a new DNA Learning Center in Sleepy Hollow, NY. Read the story »
CSHL investigators rank among world’s most highly cited
Seven researchers affiliated with CSHL are among the scientists producing the top 1 percent of the most highly-cited research in the world. Read the story »
Researchers identify gene behind spread of deadly breast cancer
Jackson Laboratory and Cold Spring Harbor Laboratory researchers uncovered novel targets for therapies related to deadly triple negative breast cancers. Read the story »
The Lab partners with award-winning magazine
Nautilus, an award-winning science magazine, has partnered with CSHL to bring the story of the lab’s scientists and research to a brand-new audience. Read the story »
CSHL wins TD Ready Challenge grant for organoid facility
CSHL is one of the recipients of the TD Ready Challenge grant to help support the upcoming organoid facility. Read the story »
New trustees bolster CSHL board
Cold Spring Harbor Laboratory welcomes three new members to its Board of Trustees. Read the story »
Adrian Krainer wins 2019 Peter Speiser Award
Professor Adrian Krainer was awarded the Peter Speiser Award for advances in the pharmaceutical sciences. Read the story »
Nicholas Tonks named 2019 AAAS Fellow
CSHL Professor Nicholas Tonks is being honored as a 2019 AAAS Fellow for his work on signal transduction and the discovery of PTP. Read the story »
Milestone reached in new leukemia drug
Salt-Inducible Kinase 3 (SIK3) could be a good therapeutic candidate for treating MLL translocation positive subtype of leukemia. Read the story »
The difference between an expert’s brain and a novice’s
Researchers use computational models to observe how changing neural activity can help mice learn new tasks and make better decisions. Read the story »
Vakoc wins Paul Marks Prize for cancer research
Professor Chris Vakoc was awarded The Paul Marks Prize for Cancer Research for his ongoing contributions to the understanding of cancer. Read the story »
14th annual Double Helix Medals dinner raises over $4 million
CSHL’s 2019 Double Helix Medals dinner honored the contributions of Dr. Nancy Wexler and Boomer Esiason. Read the story »
Scientists take action to prevent sexual harassment and bias
Scientists gathered at Banbury Center last year to discuss ways to prevent gender bias and sexual harassment in science. Read the story »
High school senior wins big in Breakthrough Junior Challenge
Winning the 2019 Breakthrough Junior Challenge, student Jeffery Chen earned his high school a $100,000 science lab designed by the DNA Learning Center. Read the story »
Historic lab at CSHL transformed for future cancer research
NY Governor Andrew Cuomo cut the ribbon for CSHL’s renovated Demerec lab space, marking the beginning of a new chapter for the historied building. Read the story »
CSHL named Top Long Island Workplace for second year
CSHL is named a Top Long Island Workplace by Newsday for the second year in a row. Read the story »
Researchers double sorghum grain number to improve food supply
A set of hormone-controlling genes may be the key to doubling grain number in sorghum plants. Read the story »
CSHL postdocs receive NARSAD Young Investigator Grants
Two CSHL neuroscience postdocs conducting neurobiological and psychiatric research received the 2019 NARSAD Young Investigators grant. Read the story »
Seeking better treatment for ALS, Lou Gehrig’s disease
Researchers found that ‘jumping genes’ were de-silenced in post-mortem tissue samples of ALS patients. Read the story »
Adrian Krainer elected to National Academy of Medicine
Professor Adrian Krainer joins the National Academy of Medicine in honor of his groundbreaking work on SMA. Read the story »
BARseq builds a better brain map
Created by CSHL neuroscientists, BARseq is capable of mapping connections within a brain at single-neuron resolution while tracing their gene expression. Read the story »
Effective vaccines for Lyme disease are needed
A new report reiterates the need to stop Lyme disease and defines a strategy for developing effective vaccines against it. Read the story »
New brain research could change how concussions are treated
Blood vessel damage seems to be more widespread than nerve damage in patients with traumatic brain injuries. Read the story »
Adrian Krainer wins Zülch Prize for lifesaving SMA Treatment
Professor Adrian Krainer is awarded the K-J. Zülch Prize for the development and testing of a first-of-its-kind treatment for spinal muscular atrophy. Read the story »
How Henri Termeer built a biotech giant
In a new biography out from CSHL Press, John Hawkins documents Henri Termeer’s legacy in biotechnology. Read the story »
Mutant cells team up to make an even deadlier blood cancer
Two very different mutations have been identified as unexpected partners-in-crime for causing the deadly blood cancer acute myeloid leukemia. Read the story »
Transparent review in preprints
Transparent Review in Preprints (TRiP) enables journals and peer review services to post peer reviews of manuscripts on CSHL’s preprint server bioRxiv. Read the story »
How to build more trust in science
Some of the world’s leading custodians of scientific research integrity met at CSHL’s Banbury Center to find out new ways to build trust in science. Read the story »
Discovery could improve MDS cancer treatment
Researchers have discovered a promising new target for treating myelodysplastic syndrome (MDS), a common and lethal blood cancer. Read the story »
Zachary Lippman named 2019 MacArthur Fellow
Cold Spring Harbor Laboratory Professor and HHMI Investigator Zachary Lippman has been named a 2019 MacArthur Fellow. Read the story »
Mice, like humans, fidget when deep in thought
Mice seemed to fidget while making decisions, prompting neuroscientists to think more about the connection between movement and cognition. Read the story »
Peter Koo wants to understand how machines learn biology
Dr. Peter Koo joins the CSHL faculty as an assistant professor. His focus is on exploring how artificial intelligence integrates with biology and genomics. Read the story »
The next agricultural revolution is here
After reviewing decades of plant research, scientists suggest that with past lessons and modern tools, the next agricultural revolution is at hand. Read the story »
Cancer drugs don’t always work as intended, researchers warn
Ten experimental cancer drugs kill tumors in ways that are entirely different than how clinicians thought they did, revealing important insights. Read the story »
Overcoming resistance in pancreatic cancer
Controlling pancreatic tumor proliferation by targeting malignancy-specific resistance pathways in response to AKT and MAPK blockade. Read the story »
Remembering David Koch
CSHL Board of Trustees, faculty and administration mourn the passing of David H. Koch, a supporter of cancer researcher. Read the story »
Are smart robots a threat?
In a Q&A, Neuroscientist Anthony Zador explains how neuroscience can inform machine learning, and why he’s not worried about a robot apocalypse. Read the story »
Understanding the animal brain could help robots wash your dishes
The field of machine learning still has a lot it can glean from neuroscience, especially in how evolution shapes an animal brain. Read the story »
New brain map could improve AI algorithms for machine vision
A revised view of the primate visual system may serve as a future reference for understanding how vision works in humans. Read the story »
CSHL graduate student wins HHMI fellowship
WSBS student David Johnson won a 2019 Gilliam Fellowships for Advanced Study for leadership and diversity in science. Read the story »
Understanding pregnancy’s effects on breast cancer risk
CSHL researchers authored a review in the journal Cell covering the landscape of breast cancer research. Read the story »
Urban Barcode Project showcases student research in biodiversity
The eighth annual Urban Barcode Project Symposium had young scientists measuring the biodiversity of New York City. Read the story »
Quantifying how the brain smells
Neuroscience researchers at CSHL are trying to figure out how the brain processes smells and what features of odors are important in that process. Read the story »
Sheltzer wins Presidential Early Career Award
CSHL Fellow Jason Sheltzer is a recipient of the Presidential Early Career Award for Scientists and Engineers for his work in cancer research. Read the story »
Laura Slatkin elected to CSHL Board of Trustees
Co-founder of NEXT for AUTISM Laura Slatkin joins the Cold Spring Harbor Laboratory Board of Trustees. Read the story »
Cancer cell’s “self eating” tactic may be its weakness
Pancreatic cancer cells are eating their own mitochondria to survive and spread. New research reveals how, hinting at a possible new drug target. Read the story »
CSHL ranked #1 in research output worldwide
The scientific journal Nature named Cold Spring Harbor Laboratory as the top academic research institution in its annual index. Read the story »
Lee awarded Chan Zuckerberg Initiative Human Cell Atlas grant
Assistant Professor Je H. Lee has been named a recipient of one of the Seed Networks for the Human Cell Atlas to study breast tissue. Read the story »
Sugars that coat proteins are a possible drug target for pancreatitis
CA19-9, a complex sugar structure coating proteins, represents a possible drug target for treatment of pancreatitis and prevention of pancreatic cancer. Read the story »
2019 CSHL Open House was a hit!
Over 650 neighbors and science enthusiasts visited the 2019 Open House at CSHL. Read the story »
Special fibroblasts help pancreatic cancer cells evade immune detection
Researchers found a specific type of cancer-associated fibroblast interacts with the immune system to help pancreatic cancer cells stay under the radar. Read the story »
Norovirus structures could help develop treatments for food poisoning
Researchers at CSHL used cryo-EM to reconstruct the structures of four different strains of human noroviruses, which cause food poisoning. Read the story »
Fighting cancer in 3D
David Tuveson, Director of the CSHL Cancer Center, shares insights about his work on organoid technology. Read the story »
New preprint server for the health sciences announced today
CSHL, Yale University, and BMJ launch medRxiv, a free preprint service for the medical and health sciences. Read the story »
Plan Universal calls on funders to encourage preprints
bioRxiv founders propose new plan to encourage organizations to make research readily available via preprint servers. Read the story »
CSHL celebrates 20 years of graduate school at 2019 commencement
The Watson School of Biological Sciences held its 16th commencement, with seven researchers graduating with doctoral degrees. Read the story »
Honorary degrees to former CSHL leaders
From pioneering eukaryotic gene regulation to directing cancer research, here are the alumni being awarded honorary Doctor of Science degrees. Read the story »
Watson School alumni spotlights
This year, Watson School celebrates the 20th anniversary of its first entering class and looks back at some notable alumni from over the years. Read the story »
Watson School 2019 Ph.D.s
Seven students were awarded Ph.D. degrees from Watson School this May. Here, they reflect on their time at the Laboratory as they look to the future. Read the story »
Enzyme PHLPP2 could be a viable drug target for treating prostate cancer
Researchers have identified an enzyme called Phlpp2 as an attractive drug target for treating prostate cancer. Read the story »
Remembering John Cairns, CSHL Director, 1963-1968
CSHL celebrates the achievements of the late Dr. John Cairns, lab director from 1963 to 1968. Read the story »
Andrea Schorn zooms in on small RNAs in the cell
Dr. Andrea Schorn joins CSHL faculty as research assistant professor. Her focus is exploring transposable elements in the genome of mammalian cells. Read the story »
Cold Spring Harbor Laboratory announces exclusive license with plant breeding start-up Inari
CSHL announced a licensing agreement with partner Inari, a company that is advancing plant breeding by tapping nature’s genetic diversity. Read the story »
Rob Martienssen wins Martin Gibbs Medal for plant research
CSHL Professor Rob Martienssen wins the 2019 Martin Gibbs Medal for his contributions to plant biology. Read the story »
To protect stem cells, plants have diverse genetic backup plans
Experts discover how an essential genetic circuit found in all flowering plants, regardless of species, is protected in startlingly different ways. Read the story »
NIH grant awarded for interneuron research
CSHL postdoc Maggie Crow will use her NIH grant to pursue the quantification and analysis of specific types of neurons in the brain. Read the story »
President Bruce Stillman wins prestigious Gairdner Award
Dr. Bruce Stillman, President & CEO of CSHL, has been awarded the 2019 Canada Gairdner International Award for his work on eukaryotic DNA replication. Read the story »
Crop yield in maize influenced by unexpected gene ‘moonlighting’
Yield of the maize plant is tied to activity of a gene called RAMOSA3, but new evidence suggests the gene performs other unexpected functions Read the story »
Hannah Meyer joins CSHL Quantitative Biology faculty
Hannah Meyer is the newest Quantitative Biology Fellow at CSHL, studying how our immune system learns to identify and fight pathogens. Read the story »
CSHL President elected as AACR Academy Fellow
CSHL President and CEO Dr. Bruce Stillman has been elected to the AACR Academy as part of the 2019 Fellows class. Read the story »
Banbury meeting addresses neurotechnology concerns
A white paper written after an important Banbury Center meeting discusses the lack of oversight in direct-to-consumer neurotechnologies. Read the story »
New cell subtypes classified in mouse brain
To map a brain, an intuitive system for classifying neuron types is necessary. Now, a promising approach reveals new cell subtypes in the mouse brain. Read the story »
Adrian Krainer wins RNA Society’s Lifetime Achievement Award
Professor Adrian Krainer was awarded the RNA Society’s Lifetime Achievement Award for his life-saving research. Read the story »
Congressman Suozzi congratulates CSHL Partner for the Future
Partner for the Future Pragati Muthukumar received a special commendation from Congressman Tom Suozzi. Read the story »
Genetic ‘usual suspects’ identified in researchers’ new list
An exhaustive ranked list of “usual suspect” genes involved in disease may prove invaluable for future research and drug discovery. Read the story »
Chandelier neuron requires ‘Velcro-like’ molecule to form connections
How do brain cells network? Researchers have discovered an essential ingredient that facilitates one type of neuron’s many neighborly connections. Read the story »
Detailed new primate brain atlas could lead to disease insights
An international effort has mapped the marmoset brain at an unprecedented level of detail, which brings us closer to understanding the human brain. Read the story »
David McCandlish named Sloan Research Fellow
Assistant Professor David McCandlish has been named a 2019 Sloan Research Fellow for his promising work in the field of quantitative biology. Read the story »
bioRxiv surpasses one million monthly downloads
A recent study illustrates the success of bioRxiv, CSHL’s biology preprint server. Read the story »
Christina Renna Foundation gives $35k for pediatric cancer research
The Christina Renna Foundation donated $35,000 to CSHL for continued work on Sarcoma Research Project and research into RMS. Read the story »
CSHL Scientific Advisory Council member wins Vilcek Prize
Dr. Angelika Amon, a member of the CSHL Scientific Advisory Council, wins the Vilcek Foundation Prize for her important work in cell biology. Read the story »
CSHL Fellow Jason Sheltzer wins innovation award
CSHL Fellow Jason Sheltzer wins the Damon Runyon-Rachleff Innovation Award for his work on cancer. Read the story »
CSHL Scientific Advisory Council member wins NAS honor
Dr. Eve Marder of the CSHL Scientific Advisory Council wins the National Academy of Sciences Award in the Neurosciences. Read the story »
CSHL donates sheets to veterans in need
CSHL donated 75 bags of sheets to the United Veterans Beacon House, with the aid of the Lindenhurst Rotary Club and the Christina Renna Foundation. Read the story »
Targeting ‘hidden pocket’ for treatment of stroke and seizure
Researchers have identified a hidden molecular “pocket” in a special neuron receptor, which could lead to better treatments for stroke and seizures. Read the story »
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