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Cold Spring Harbor Laboratory announces exclusive license with plant breeding start-up Inari

April 16, 2019

Research News

CSHL announced a licensing agreement with partner Inari, a company that is advancing plant breeding by tapping nature’s genetic diversity.…

Rob Martienssen wins Martin Gibbs Medal for plant research

April 15, 2019

Institutional News

CSHL Professor Rob Martienssen wins the 2019 Martin Gibbs Medal for his contributions to plant biology.…

To protect stem cells, plants have diverse genetic backup plans

April 15, 2019

Research News

Experts discover how an essential genetic circuit found in all flowering plants, regardless of species, is protected in startlingly different ways.…

NIH grant awarded for interneuron research

April 4, 2019

Institutional News

CSHL postdoc Maggie Crow will use her NIH grant to pursue the quantification and analysis of specific types of neurons in the brain.…

President Bruce Stillman wins prestigious Gairdner Award

April 2, 2019

Institutional News

Dr. Bruce Stillman, President & CEO of CSHL, has been awarded the 2019 Canada Gairdner International Award for his work on eukaryotic DNA replication.…

Crop yield in maize influenced by unexpected gene ‘moonlighting’

April 1, 2019

Research News

Yield of the maize plant is tied to activity of a gene called RAMOSA3, but new evidence suggests the gene performs other unexpected functions…

Hannah Meyer joins CSHL Quantitative Biology faculty

March 26, 2019

Institutional News

Hannah Meyer is the newest Quantitative Biology Fellow at CSHL, studying how our immune system learns to identify and fight pathogens.…

CSHL President elected as AACR Academy Fellow

March 25, 2019

Institutional News

CSHL President and CEO Dr. Bruce Stillman has been elected to the AACR Academy as part of the 2019 Fellows class. …

Banbury meeting addresses neurotechnology concerns

March 13, 2019

Institutional News

A white paper written after an important Banbury Center meeting discusses the lack of oversight in direct-to-consumer neurotechnologies.…

New cell subtypes classified in mouse brain

March 12, 2019

Research News

To map a brain, an intuitive system for classifying neuron types is necessary. Now, a promising approach reveals new cell subtypes in the mouse brain.…

Adrian Krainer wins RNA Society’s Lifetime Achievement Award

March 8, 2019

Institutional News

Professor Adrian Krainer was awarded the RNA Society’s Lifetime Achievement Award for his life-saving research.…

Congressman Suozzi congratulates CSHL Partner for the Future

March 7, 2019

Education News

Partner for the Future Pragati Muthukumar received a special commendation from Congressman Tom Suozzi.…

Genetic ‘usual suspects’ identified in researchers’ new list

March 4, 2019

Research News

An exhaustive ranked list of “usual suspect” genes involved in disease may prove invaluable for future research and drug discovery.…

Chandelier neuron requires ‘Velcro-like’ molecule to form connections

March 4, 2019

Research News

How do brain cells network? Researchers have discovered an essential ingredient that facilitates one type of neuron’s many neighborly connections.…

Detailed new primate brain atlas could lead to disease insights

March 1, 2019

Research News

An international effort has mapped the marmoset brain at an unprecedented level of detail, which brings us closer to understanding the human brain.…

David McCandlish named Sloan Research Fellow

February 19, 2019

Institutional News

Assistant Professor David McCandlish has been named a 2019 Sloan Research Fellow for his promising work in the field of quantitative biology.…

bioRxiv surpasses one million monthly downloads

February 11, 2019

Institutional News

A recent study illustrates the success of bioRxiv, CSHL’s biology preprint server.…

Christina Renna Foundation gives $35k for pediatric cancer research

February 7, 2019

Institutional News

The Christina Renna Foundation donated $35,000 to CSHL for continued work on Sarcoma Research Project and research into RMS.…

CSHL Scientific Advisory Council member wins Vilcek Prize

February 7, 2019

Institutional News

Dr. Angelika Amon, a member of the CSHL Scientific Advisory Council, wins the Vilcek Foundation Prize for her important work in cell biology.…

CSHL Fellow Jason Sheltzer wins innovation award

January 25, 2019

Institutional News

CSHL Fellow Jason Sheltzer wins the Damon Runyon-Rachleff Innovation Award for his work on cancer.…

CSHL Scientific Advisory Council member wins NAS honor

January 25, 2019

Institutional News

Dr. Eve Marder of the CSHL Scientific Advisory Council wins the National Academy of Sciences Award in the Neurosciences.…

CSHL donates sheets to veterans in need

January 24, 2019

Institutional News

CSHL donated 75 bags of sheets to the United Veterans Beacon House, with the aid of the Lindenhurst Rotary Club and the Christina Renna Foundation.…

Targeting ‘hidden pocket’ for treatment of stroke and seizure

January 18, 2019

Research News

Researchers have identified a hidden molecular “pocket” in a special neuron receptor, which could lead to better treatments for stroke and seizures.…

Austin’s Purpose donates $10k to neuroscience research

January 18, 2019

Institutional News

Epilepsy research-supporting organization Austin’s Purpose makes a donation to continue key neuroscience research in Professor Hiro Furukawa’s lab.…

Statement by Cold Spring Harbor Laboratory addressing remarks by Dr. James D. Watson in “American Masters: Decoding Watson”

January 11, 2019

Institutional News

Statement by Cold Spring Harbor Laboratory addressing remarks by Dr. James D. Watson in “American Masters: Decoding Watson.”…

How much are we learning? Natural selection is science’s best critic

December 17, 2018

Research News

Researchers determine that natural selection and our evolutionary history may be the best guides for future research.…

Taking uncertainty out of cancer prognosis

December 11, 2018

Research News

CSHL Fellow Jason Sheltzer has analyzed nearly 20,000 cancer patient histories and genetic data to take the guesswork out of prognosis.…

National Academy of Inventors Fellow, Adrian Krainer

December 11, 2018

Institutional News

Professor Adrian Krainer has been named a NAI 2018 Fellow for his work on the first FDA-approved treatment for spinal muscular atrophy.…

Marilyn Simons elected Cold Spring Harbor Laboratory chair

December 7, 2018

Institutional News

Dr. Marilyn Simons becomes the chair of the CSHL Board of Trustees, new officers are elected, and three new trustees join the board.…

Breakthrough Prize laureates meet at CSHL

December 6, 2018

Institutional News

Breakthrough Prize winner Adrian Krainer & C. Frank Bennett reunite for the first time since their award ceremony at CSHL to discuss further project.…

Molly Hammell wins CZI award for ALS study

December 5, 2018

Institutional News

Associate Professor Molly Hammell wins award for proposed study to find transposable elements that are implicated in ALS.…

How the brain hears and fears

December 5, 2018

Research News

Researchers are studying how the brain reacts to sounds that it associates with fear, and how easy it is for the brain to learn and unlearn.…

Inconspicuous protein key to deadly blood cancer

November 29, 2018

Research News

Associate Professor Chris Vakoc and his team find that an aggressive type of leukemia is heavily-dependent on a common protein.…

AAAS names two CSHL faculty as 2018 Fellows

November 27, 2018

Institutional News

David Jackson and Jan A. Witkowski were both named 2018 AAAS Fellows for their work in the fields of agriculture and biology.…

Pancreatic cancer’s addiction could be its end

November 13, 2018

Research News

Researchers may have found a link between improper protein production and the spread of pancreatic cancer.…

13th Double Helix Medals dinner raises over $4 million

November 8, 2018

Institutional News

Dr. Priscilla Chan, Mark Zuckerberg, and Dr. Larry Norton were honored for their contributions to basic research at the Double Helix Medals dinner.…

A great place to work!

November 1, 2018

Institutional News

CSHL is named a 2018 Top Long Island Workplace by Newsday through the use of employee surveys.…

From many mice, unexpected genius

October 31, 2018

Research News

Researchers find that some individual mice are smarter than their fellow rodents, which can provide insights into decision-making.…

Thanks, National Grid Foundation for hands-on science!

October 29, 2018

Education News

The DNA Learning Center has completed the National Grid Advanced Genetics Program (NGAGP) in the Central Islip school district.…

Turning cells against pancreatic cancer

October 26, 2018

Research News

Researchers have found a way to turn cancer-supporting cells into cells that restrict the cancerous growth in the pancreas.…

New regulators of nitrogen use in plants identified

October 24, 2018

Research News

A team of CSHL plant biologists identify gene regulators that may help plants utilize nitrogen better and prevent excess nitrogen in soil.…

The big problem of small data: A new approach

October 18, 2018

Research News

You’ve heard of “big data” but what about small? Researches have crafted a modern approach that could solve a decades-old problem in statistics.…

Breakthrough Prize to CSHL professor for SMA research

October 17, 2018

Research News

Professor Adrian Krainer has received a Breakthrough Prize in Life Sciences for his work on the first FDA-approved treatment of SMA.…

Cancer research from a different perspective

October 3, 2018

Research News

CSHL Assistant Professor Tobias Janowitz discusses his patient-centric approach to studying cancer…

What’s that smell? Neuroscientists are figuring it out

October 2, 2018

Research News

Neuroscientists Florin Albeanu and Alexei Koulakov win the NIH Director’s Transformative Research Award for their project on the olfactory system…

CRISPR could bring groundcherries to market

October 1, 2018

Research News

CSHL Professor Zachary Lippman uses CRISPR to make the groundcherry more suitable for large-scale farming…

Computational neuroscientist wins BRAIN grant

September 27, 2018

Institutional News

Assistant Professor Tatiana Engel earns grant to build tools that will help build better models of the brain…

CSHL podcast wins prestigious PR News award

September 27, 2018

Institutional News

CSHL’s Base Pairs podcast wins the Platinum PR Award for Best Podcast from PR News…

How a sleeping cancer awakens and metastasizes

September 27, 2018

Research News

Chronic inflammation can reawaken dormant cancer cells and spur metastasis. It may be preventable…

Future scientists take to the bench

September 20, 2018

Education News

The latest class of the Partners for the Future program visit the Lab and meet their mentors as they get to work…

Path to cancer in the brain set by protein CHD5

September 14, 2018

Research News

Researchers find that protein keeps neural stem cells from activating too soon and hindering brain development…

Predicting how splicing errors impact disease risk

August 30, 2018

Research News

New research helps correlate genetic mutations with errors in RNA splicing that can cause serious illness…

CSHL team wins scientific case competition

August 27, 2018

Institutional News

Five CSHL postdocs and graduate students won first place at the fifth annual Tufts New England Case Competition (TUNECC).…

CSHL helps ring opening bell at Nasdaq

August 21, 2018

Institutional News

CSHL Professor Adrian Krainer and his team join the Spinal Muscular Atrophy (SMA) Foundation in ringing the Nasdaq opening bell…

Undergrad symposium highlights lessons in the lab

August 20, 2018

Education Research News

The 2018 Undergraduate Research Program class presents their projects after working for ten weeks in various labs across campus.…

Dr. Zador wins Transformative Investigator award

August 8, 2018

Institutional News

CSHL professor Anthony Zador wins Gill Symposium prize for his innovative work on MAPseq…

Seeding citizen science with DNA barcoding

July 18, 2018

Education News

Teachers trained in DNA barcoding can mentor students as they become citizen scientists investigating what interests them most…

Massive genome havoc in breast cancer is revealed

July 12, 2018

Research News

Researchers have made a highly detailed map of 20,000 structural variations in a cancer cell’s genome…

CSHL Fellow Semir Beyaz wins three awards

July 11, 2018

Institutional News

Semir Beyaz has won three awards for his research on the impact of dietary choices on the body’s immunity against cancer…

Nicholas Tonks wins prestigious ASBMB award

July 3, 2018

Institutional News

Professor Nicholas Tonks wins Earl and Thressa Stadtman Distinguished Scientist Award from the American Society for Biochemistry and Molecular Biology…

CSHL spinoff wins investment prize

June 29, 2018

Research News

CSHL spinoff company MapNeuro Inc., which uses tech developed in Zador lab, wins 2018 Seed Capital Prize from Alexandria LaunchLabs…

Progress toward improved Wilson’s disease drug

June 27, 2018

Research News

Encouraging early results in a potential new treatment for Wilson's disease…

Researchers discover new type of lung cancer

June 25, 2018

Research News

Researchers have discovered a new form of lung cancer.…

Postdoc wins Indian National Science Academy prize

June 25, 2018

Institutional News

Dhananjay Huilgol, a postdoc in Professor Joshua Huang’s lab, wins one of India’s highest honors for young investigators…

Nation’s cancer centers endorse HPV vaccination

June 8, 2018

Research News

Dr. Stillman and Dr. Tuveson joined with the leaders of other institutions nationwide in endorsing a statement regarding the HPV vaccine…

Alexander Dobin dives into genomic data

June 8, 2018

Research News

Alexander Dobin joins the faculty as its newest assistant professor, working on the computational side of genomics research…

Suffrage Science award to Mikala Egeblad

June 8, 2018

Institutional News

Egeblad and 10 other female scientists from around the world were presented with heirloom jewelry at the Suffrage Science awards ceremony…

A better way to trace neuronal pathways

June 6, 2018

Research News

Researchers have improved a key method used to map circuits in the brain…

Microbial masterpieces win ASM Agar Art Contest

June 4, 2018

Education News

Science-inspired artworks created at CSHL’s DNA Learning Center win in the 2018 American Society for Microbiology Agar Art Contest…

Organoid profiling personalizes treatments for pancreatic cancer

May 31, 2018

Research News

Pancreatic organoids grown from patients' tumors make precision medicine possible…

Prof. Zachary Lippman named Blavatnik Award finalist

May 30, 2018

Institutional News

Professor Zachary Lippman was chosen as a Finalist in Life Sciences for the 2018 Blavatnik National Awards…

Scientists show how brain circuit generates anxiety

May 29, 2018

Research News

Researchers have identified a circuit in the brain that drives anxiety…

CSHL’s Zachary Lippman named HHMI Investigator

May 23, 2018

Institutional News

CSHL Professor Zach Lippman is selected as an HHMI investigator, in recognition of his innovative work in the field of plant genetics…

Pershing Square Sohn prize to Camila dos Santos

May 22, 2018

Institutional News

Assistant Professor Camila dos Santos, Ph.D., has been awarded the Pershing Square Sohn Prize for Young Investigators in Cancer Research.…

How pancreatic cancer spreads after surgery

May 17, 2018

Research News

Researchers have solved a mystery about how pancreatic cancer spreads…

High schoolers reveal fraudulent herbal medicines

May 14, 2018

Education News

Some herbal products are not what they claim to be. These high school students and their mentor used DNA to investigate…

How key brain receptor works in hostile conditions

May 9, 2018

Research News

A structural variation enables a key brain receptor to function in a hostile environment…

Cold Spring Harbor Laboratory celebrates its 15th commencement

May 1, 2018

Education News

Five students from the Watson School of Biological Sciences graduate, with special keynote speeches from Drs. David and Leon Botstein…

Therapeutic RNA corrects splicing defect that causes familial dysautonomia

April 30, 2018

Research News

A team provides proof of concept for an RNA drug correcting an error in RNA splicing that causes familial dysautonomia (FD)…

Watson School 2018 Ph.D.s

April 27, 2018

Education News

CSHL celebrates its 15th commencement, with five promising Ph.D. students graduating and honorary degrees presented to David and Leon Botstein…

David Tuveson elected to the AACR Board of Directors

April 13, 2018

Institutional Research News

CSHL Professor David Tuveson was elected to the Board of Directors of the American Association for Cancer Research for the 2018 - 2021 term…

Newly identified genetic mutation results in intellectual disability and developmental delay

April 12, 2018

Research News

Scientists have identified a new illness caused by a genetic mutation that gives rise to a wide range of symptoms including intellectual disability…

CSHL’s Base Pairs is a finalist for the 2018 Webby Awards

April 6, 2018

Institutional News

CSHL's podcast Base Pairs was nominated for a prestigious Webby award for best Science and Education podcast…

Andrew Whiteley appointed VP of Business Development and Technology Transfer at CSHL

April 3, 2018

Institutional News

Life science business leader Andrew Whiteley becomes the Vice President of CSHL's Business Development and Technology Transfer department.…

Study reveals a way to make prostate cancer cells run out of energy and die

April 3, 2018

Research News

In lethal prostate cancer, the gene PTEN is often missing. In such cases, one effective treatment may be to administer drugs that inhibit mitochondria…

Revolutionary brain-mapping technique provides new blueprint for cortical connections

March 28, 2018

Research News

Researchers used MAPseq, a revolutionary brain mapping method, to make a discovery that will force neuroscientists to rethink how areas of the cortex …

Evans Foundation MDS Young Investigator Award to Lingbo Zhang

March 28, 2018

Research News

CSHL Fellow Lingbo Zhang received a Young Investigator Award from the Edward P. Evans Foundation…

Unique communication strategy discovered in pathway controlling plant growth

March 22, 2018

Research News

Scientists have identified a receptor on plant stem cells that can issue different instructions about how the plant will grow.…

Ratner and Weisbrod join Cold Spring Harbor Laboratory Board of Trustees

March 15, 2018

Institutional News

Bruce Ratner and Stuart Weisbrod were elected to the Cold Spring Harbor Laboratory Board of Trustees…

CRISPR-based system identifies important new drug targets in a deadly leukemia

March 8, 2018

Research News

CRISPR was used to find 2 new druggable targets in a deadly leukemia…

New method identifies splicing biomarkers for liver cancer

March 2, 2018

Research News

Researchers have developed a method for identifying splicing-based biomarkers for liver cancer…

New CSHL Fellow studies nexus of diet, metabolism, and cancer

March 1, 2018

Research News

CSHL Fellow Semir Beyaz works on the effects of what we eat and how it affect the incidence of colorectal cancers.…

The secret to tripling the number of grains in sorghum and perhaps other staple crops

February 26, 2018

Research News

A simple genetic modification can triple grain production in sorghum, a drought-tolerant plant that is an important source of food and animal feed.…

Science self-corrects: cancer gene does not pass reproducibility test

February 13, 2018

Research News

CSHL Fellow Jason Sheltzer and his research team use CRISPR to discover that MELK is not actually involved in cancer.…

Autism genetics study calls attention to impaired motor skills, general cognitive impairment

February 7, 2018

Research News

New research on the genetic causes of autism calls attention to diminished motor skills and suggests the importance of broad cognitive impairment…

PLOS and CSHL enter agreement to enable preprint posting on bioRxiv

February 6, 2018

Institutional News

The Public Library of Science (PLOS) will now be automatically posting papers submitted to its journal on bioRxiv, CSHL's preprint server…

Dr. Leemor Joshua-Tor honored with Mildred Cohn Award from ASBMB

February 2, 2018

Institutional News

Professor Leemor Joshua-Tor receives the American Society for Biochemistry and Molecular Biology’s 2018 Mildred Cohn Award in Biological Chemistry.…

More rice, please: 13 rice genomes reveal ways to keep up with ever-growing population

February 1, 2018

Research News

Rice provides 20% of calories consumed. As the population grows toward 9 billion and the climate shifts, we'll need to grow more rice in more places.…

At CSHL, Congressman Suozzi celebrates scientific achievements of local HS students

January 29, 2018

Education News

Congressman Suozzi hosts congratulatory event at CSHL for high school science competition winners, including two Partners for the Future participants…

Evolving sets of gene regulators explain some of our differences from other primates

January 29, 2018

Research News

What makes us different from our primate relatives? Gene regulation is one important evolutionary factor…

New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes

January 26, 2018

Research News

CSHL scientists have designed software that enables biologists to determine with unprecedented accuracy how much protein a given cell is making…

Christina Renna Foundation raises $30,000 for continuing pediatric cancer research at CSHL

January 22, 2018

Institutional News

The Christina Renna Foundation donates over $30,000 for rhabdomyosarcoma research, and honors Associate Professor Chris Vakoc with its research award…

CSHL’s Rob Martienssen honored with prestigious Barbara McClintock Prize

January 19, 2018

Institutional News

Plant geneticist Rob Martienssen awarded prestigious McClintock Prize…

Counting chromosomes: Plant scientists solve a century-old mystery about reproduction

January 18, 2018

Research News

Geneticists have solved a century-old mystery by discovering a remarkable mechanism that enables plants to count their chromosomes…

YouTube videos earned her school a new lab from CSHL. Here’s how.

January 10, 2018

Education News

Student wins back-to-back prizes from Silicon Valley. One such prize, a lab designed by CSHL’s DNA Learning Center, was awarded to her high school.…

Molecular decoy helps researchers halt and reverse acute leukemia in mice

January 8, 2018

Research News

By throwing a molecular wrench into the gears of a machine that sets genes into motion, researchers were able to get leukemias to 'melt away.'…

A Cure Within documents the human stories behind cancer immunotherapy

December 28, 2017

Institutional News

Immunotherapy as a cancer treatment may be cutting-edge, but it has a history. It’s the result of years of work by many dedicated researchers, some…

CSHL’s Bo Li receives BRAIN Initiative funding

December 28, 2017

Research News

CSHL Professor Bo Li and two collaborators at Oregon Health & Science University (OHSU) have been awarded a new grant under the BRAIN Initiative…

David Spector is named ASCB Fellow

December 11, 2017

Institutional News

David L. Spector was named a fellow of The American Society for Cell Biology…

Dr. Anne Churchland honored with Marshall Award for promoting women in science

December 11, 2017

Institutional News

Associate Professor Anne Churchland was honored with The Louise Hanson Marshall Special Recognition Award…

Next Generation Lyme disease tests found efficacious and ready for clinical arena

December 7, 2017

Research News

Experts find that current protocols for Lyme disease lacks the accuracy and sensitivity that next-generation testing can provide.…

New method to determine before surgery which prostate tumors pose a lethal threat

December 1, 2017

Research News

The news about prostate cancer can be confusing. It’s the third most common cancer type among Americans…

A transformative partnership

November 22, 2017

Institutional News

New York Governor Andrew M. Cuomo visited Cold Spring Harbor Laboratory to break ground on the new $75 million Center for Therapeutics Research.…

“Hi, my name is Brian”…“and I’m Andrea”

November 22, 2017

Research News

We’re the hosts of Base Pairs, a podcast from Cold Spring Harbor Laboratory that tells stories about the power of genetic information—past, present an…

Hungry for science

November 22, 2017

Institutional News

The 12th annual Women’s Partnership for Science luncheon celebrated honorary director of the CSHL Association Freddie Staller.…

Welcome back, Dr. Myat

November 21, 2017

Education News

Monn Monn Myat, Ph.D., is the new Associate Dean of the Watson School of Biological Sciences.…

Additional brain power

November 21, 2017

Research News

For neuroscientists, the brain presents an almost endless number of mysteries to be solved.…

Toasting serendipity

November 21, 2017

Research News

Four decades ago, scientists made a discovery that “completely transformed all of biology,” according to Nobelist James Watson. …

Light, cryptochromes, action…

November 21, 2017

Research News

Assistant Professor Ullas Pedmale has received the National Institutes of Health "Outstanding Investigator Award."…

Hannon named director of Cancer Research UK Cambridge Institute

November 21, 2017

Education News

Dr. Greg Hannon has been named the new director of the Cancer Research UK Cambridge Institute, effective February 1, 2018.…

12th Double Helix Medals dinner raises $4.5 million for research & education at Cold Spring Harbor Laboratory

November 16, 2017

Institutional News

More than $4.5 million was raised last night at Cold Spring Harbor Laboratory’s (CSHL) 12th Double Helix Medals dinner (DHMD).…

Friends of T.J. present $50,000 gift for ongoing rhabdomyosarcoma research

November 7, 2017

Institutional News

The Friends of T.J. Foundation presented CSHL Associate Professor Chris Vakoc with a check for $50,000 for his ongoing rhabdomysarcoma research…

Fantastic journey: how newborn neurons find their proper place in the brain

November 2, 2017

Research News

Neuroscientists have clarified the mechanism used by newly born neurons in mice to migrate to very specific areas.…

New leadership roles in BRAIN Initiative and International Brain Lab reflect CSHL’s excellence in neuroscience

October 24, 2017

Research News

The BRAIN Initiative Cell Census Network establishes a Center and a Collaboratory for the Mouse Brain Cell Atlas at Cold Spring Harbor Laboratory …

Cryo-EM imaging suggests how the double helix separates during replication

October 23, 2017

Research News

Special cryo-EM imaging helps figure out how the double helix of DNA separates when it replicates…

Research revises our knowledge of how the brain learns to fear

October 23, 2017

Research News

A team at Cold Spring Harbor Laboratory led by Professor Bo Li found evidence indicating the central amygdala is key to to aversive learning.…

Masthead Cove Yacht Club raises over $6000 for CSHL research at annual race

October 18, 2017

Institutional News

Members of the Masthead Cove Yacht Club (MCYC) raised $6,700 from their annual Masthead Race on August 13.…

Governor Cuomo breaks ground on $75 million Cold Spring Harbor Laboratory Center for Therapeutics Research

October 12, 2017

Institutional News

NY Governor Andrew M. Cuomo visited Cold Spring Harbor Laboratory (CSHL) this morning to break ground on the new $75 million Center for Therapeutics.…

First cell-type census of mouse brains: surprises about structure, male-female differences

October 5, 2017

Research News

A multiyear project in the Brain Initiative, qBrain is already revealing the brain as never before.…

16th Women’s Partnership for Science raises over $200,000 for disease research at Cold Spring Harbor Laboratory

September 27, 2017

Institutional News

Cold Spring Harbor Laboratory held the 16th annual Women's Partnership for Science luncheon, a summer staple among New York's female philanthropists.…

Neuron types in the brain are defined by gene activity that shapes their communication patterns

September 21, 2017

Research News

Neurons are defined by determining which cells they connect with and how they communicate across synapses …

Plant geneticists develop a new application of CRISPR to break yield barriers in crops

September 14, 2017

Research News

Mutating regulatory regions varies yield traits the way a dimmer switch controls a light bulb…

Research reveals “exquisite selectivity” of neuronal wiring in the cerebral cortex

August 21, 2017

Research News

Inhibitory chandelier cells receive and transmit information from different ensembles of excitatory cells in their cortical neighborhood …

2nd Annual WiSE Summer Party provides needed networking opportunity

August 18, 2017

Institutional News

CSHL Women in Science and Engineering and the Postdoctoral Liaison Committee co-hosted the 2nd annual Greater NYC WiSE Summer Beach Party…

Structural view suggests RNAi machinery multiplies its efficiency in repressing gene expression

August 3, 2017

Research News

Leemor Joshua-Tor publishes atomic-resolution pictures and an analysis of RNAi machinery…

CSHL’s Kepecs receives BRAIN Initiative grant to develop tools to guide behavioral research

August 1, 2017

Institutional News

Dr. Adam Kepecs receives grant to develop conceptual infrastructure for behavioral neuroscience research…

Long-sought mechanism of metastasis is discovered in pancreatic cancer

July 27, 2017

Research News

An epigenetic factor reprograms gene enhancers, enabling cancer cells to “remember” an earlier developmental state and causing metastasis. …

Team traces masculinization in mice to estrogen receptor in inhibitory neurons

July 20, 2017

Research News

CSHL researchers discover when ERα receptors are deleted in the brains of male mice, they do not exhibit typical "masculine" behaviors during puberty.…

Library of CRISPR targeting sequences increases power and accuracy of the gene-editing method

July 20, 2017

Research News

New library of RNA sequences that can be used by researchers to direct the CRISPR-cas9 complex to cut DNA with unprecedented precision.…

Freeze-frames of enzymes in action have implications for a new cancer treatment concept

July 3, 2017

Research News

TUTase enzymes interact with let-7, a regulator of development; targeting them could help control certain cancers.…

Newly identified small RNA fragments defend the genome when it’s ‘naked’

June 29, 2017

Research News

Fragments snipped from tRNAs protect embryonic stem cells while they’re being epigenetically reprogrammed.…

Over $300,000 raised for research and education at 24th annual golf outing

June 26, 2017

Institutional News

Over 180 golfers took to the greens at Piping Rock Club at Cold Spring Harbor Laboratory’s 24th annual golf tournament.…

Latest advances in malaria research in free eBook by Cold Spring Harbor Laboratory Press

June 26, 2017

Institutional News

J.C. Flowers Foundation grant gives practitioners in malaria-endemic areas access to a critical resource…

New statistical method finds shared ancestral gene variants involved in autism’s cause

June 21, 2017

Research News

Researchers find children with autism are genetically more like other autistic children than their unaffected siblings.…

Open House brings 500+ new friends to Cold Spring Harbor Laboratory campus

June 13, 2017

Education Institutional News

Cold Spring Harbor Laboratory (CSHL) welcomed 500+ new friends on June 10, 2017 to share the thrill of scientific discovery.…

Detailed new ‘reference’ genome for maize shows the plant has deep resources for continued adaptation

June 12, 2017

Research News

A new, much more detailed reference genome for maize, or corn, as it is called in the U.S., provides new insight into the crop.…

A protein that stem cells require could be a target in killing breast cancer cells

June 1, 2017

Research News

Cancer cells, like stem cells, have the ability to multiply indefinitely but epigenetic factor BPTF may be a shared weakness.…

Fine-tuning dosage of mutant genes unleashes long-trapped yield potential in tomato plants

May 18, 2017

Research News

Understanding gene interactions can enable breeders to break existing productivity barriers in agriculture.…

CSHL to lead international team developing next-generation organoid cancer research

May 11, 2017

Research News

Cold Spring Harbor Laboratory (CSHL) has been awarded a research subcontract by Leidos Biomedical Research to lead a Cancer Model Development Center (CMDC) for pancreatic, breast, colorectal, lung, liver and other upper-gastrointestinal cancers.…

Nobel laureate Dr. Carol Greider gives keynote at Cold Spring Harbor Laboratory graduation

May 8, 2017

Education News

Eight new Ph.D.s join 90 alumni who have earned a degree from the Watson School of Biological Sciences in the 18 years since its accreditation.…

Newly discovered mutations impair key cell pathways in pancreatic cancer

May 8, 2017

Research News

Researchers have found important new clues to the development of pancreatic cancer.…

Pershing Square Sohn cancer research prize awarded to CSHL’s Dr. Mikala Egeblad

May 8, 2017

Research News

Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad, Ph.D., has been awarded the Pershing Square Sohn Prize.…

CSHL’s Dr. Leemor Joshua-Tor is elected to The National Academy of Sciences

May 2, 2017

Research News

Professor Leemor Joshua-Tor has been elected to The National Academy of Sciences (NAS).…

Cold Spring Harbor Laboratory to boost sharing of global scientific research in collaboration with the Chan Zuckerberg Initiative

April 26, 2017

Institutional Research News

To accelerate the pace of scientific discovery, the bioRxiv preprint service will advance free distribution of research manuscript drafts.…

CSHL’s Dr. Leemor Joshua-Tor Elected to American Academy of Arts and Sciences

April 14, 2017

Research News

Professor Leemor Joshua-Tor is among 228 newly elected members of The American Academy of Arts and Sciences…

New research explains why even targeted therapies eventually fail in lung cancer

March 29, 2017

Research News

Dr. Sordella and her team propose a novel theory of how some cancers circumvent the killing power of targeted therapies.…

Research suggests a possible role for a storm of ‘jumping genes’ in ALS

March 27, 2017

Research News

New research demonstrates that some transposons are no longer effectively inhibited, resulting in a storm of jumping genes, leading to DNA damage.…

Trinity College President Joins Board of Cold Spring Harbor Laboratory

March 21, 2017

Institutional News

Dr. Joanne Berger-Sweeney, president of Trinity College, was elected to the CSHL Board of Trustees.…

Protein complex that takes first steps in human DNA replication dance is captured at high atomic resolution

March 16, 2017

Research News

Human ORC complex captured in action in x-ray crystallography and cryo-EM…

Dopamine neurons factor ambiguity into predictions that enable us to “win big and win often”

March 9, 2017

Research News

Researchers describe how dopamine-releasing neurons weigh the ambiguity of sensory information, indicating that neurons are highly sophisticated.…

The Children’s Heart Foundation awards $50,000 to CSHL researcher

February 28, 2017

Institutional News

The New York Chapter of The Children’s Heart Foundation (CHF) presented Dr. Michael Ronemus of Cold Spring Harbor Laboratory (CSHL) a $50,000 grant.…

Discovery of distinct cell subtypes around tumors helps explain why pancreatic cancer is so hard to treat

February 23, 2017

Research News

Researchers finds that stroma,“wound”-like tissue that surrounds the tumors, helps explain why pancreatic cancer is so resistant to treatment.…

Researchers identify “Achilles’ heel” of PTEN that helps drive prostate cancer progression

February 13, 2017

Research News

Researchers at CSHL have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it.…

CSHL statement regarding Executive Order on border security and immigration

February 1, 2017

Institutional News

CSHL statement regarding Executive Order on border security and immigration…

In mouse model of Rett syndrome, research reveals how adult learning is impaired in females

January 18, 2017

Research News

Researchers found that the failure of the Mecp2 gene, which leads to Rett syndrome, has biological consequences later in life.…

Cancer research biobank formed by Northwell Health and Indivumed will enhance CSHL-Northwell alliance

January 17, 2017

Institutional News

Northwell Health and Indivumed collaborate to greatly expand cancer biobanking activities within Northwell Health to develop medical approaches.…

Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments

January 12, 2017

Research News

Pre-malignant aneuploid cells grew more slowly and formed smaller tumors than comparable cells with normal chromosome number, CSHL researchers found.…

CSHL joins NCI-designated cancer centers in endorsing updated HPV vaccination recommendations

January 11, 2017

Institutional News

Dr. Stillman and Dr. Tuveson joined with the leaders of other institutions nationwide in endorsing a statement regarding the HPV vaccine.…

Plus-sized fly: a model to understand the mechanisms underlying human obesity

January 10, 2017

Research News

The fly sheds light on how the brain acts to signal “fullness” and the possibility of conferring resilience against the impact of high-fat diets…

FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL

December 24, 2016

Research News

Nusinersen (Spinraza) will be used to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA).…

Dr. Robert Maki joins Northwell Health Cancer Institute and CSHL to direct Center for New Cancer Therapies

December 12, 2016

Research News

Dr. Robert G. Maki an internationally-renowned sarcoma cancer physician and researcher, joins the leadership of the Northwell Health Cancer Institute.…

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

December 9, 2016

Research News

Truncated p53 proteins, presumed unimportant, now point to new drug targets for some of "the hardest cancers"…

Gene editing yields tomatoes that flower and ripen weeks earlier

December 5, 2016

Research News

Researchers use CRISPR to expand the geographical range of important food crops.…

11th Double Helix Medals raises $4.3 million for biomedical research and education at Cold Spring Harbor Laboratory

December 2, 2016

Institutional News

More than $4.3 million was raised last night at Cold Spring Harbor Laboratory’s 11th Double Helix Medals dinner, honoring Alan Alda and P. Roy Vagelos…

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

December 1, 2016

Research News

Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia.…

Dr. David Tuveson named Director, NCI-Designated Cancer Center at Cold Spring Harbor Laboratory

November 29, 2016

Institutional News

Dr. David Tuveson, M.D., Ph.D., succeeds Dr. Bruce Stillman as Director of the Cold Spring Harbor Laboratory (CSHL) Cancer Center.…

Focus on quiescent cells brings to light the essential role of RNA interference in transcription control

November 9, 2016

Research News

RNAi and other epigenetic processes induce changes in where and when specific genes are expressed without altering their genetic code.…

Pancreas and colon tumors reprogram the liver, causing wasting and short-circuiting body’s immune response

November 8, 2016

Research News

Research reveals a mechanism that causes wasting in cancer and tests a way to reverse it.…

Gene network controls how many flowers and fruits plants will produce during critical growth window

November 7, 2016

Research News

Researchers use RNA sequencing to identify a network of genes that work together to determine the duration of a critical window for growth.…

Our most common infection-fighting white blood cells can be hijacked to support cancer spread

October 19, 2016

Research News

Neutrophils, the most common type of white blood cell, can be taken over by cancer cells and used as an aid in metastasis.…

Masthead Cove Yacht Club raises over $7000 for CSHL research at annual race

October 19, 2016

Institutional News

Members of the Masthead Cove Yacht Club (MCYC) raised $7,007 from their annual Masthead Race on August 14, 2016.…

Non-coding portions of genome are found to play role in cancer

September 27, 2016

Research News

CSHL scientists test an antisense method of targeting long noncoding RNAs overexpressed in breast cancers.…

Was it better or worse than you expected? Your basal ganglia know – so you can act accordingly

September 21, 2016

Research News

Researchers have uncovered a neural circuit that processes evaluations and have succeeded in identifying its sources.…

Innovative tools will shed clarifying light on inhibitory neurons

September 21, 2016

Research News

Researchers at Cold Spring Harbor Laboratory created a set of tools that combine genetic markers and virus particles to target GABA cell types.…

15th Women’s Partnership for Science luncheon features Lasker Prize winner Evelyn Witkin

September 21, 2016

Institutional News

15th Annual Women's Partnership raises over $200,000 for disease research at Cold Spring Harbor Laboratory…

Preprint server bioRxiv receives additional major funding

August 26, 2016

Institutional News

Increased support will fuel continued growth and technical development of the increasingly prominent biomedical preprint service.…

Revolutionary method to map the brain at single-neuron resolution is successfully demonstrated

August 19, 2016

Research News

MAPseq can trace the long-range projections of large numbers of individual neurons from a specific region to wherever they lead in the brain.…

Candidate drug for spinal muscular atrophy, with roots in CSHL research, passes major hurdle

August 4, 2016

Research News

Biotechnology firms Biogen and Ionis Pharmaceuticals cut short a phase-3 clinical trial for the investigational drug nusinersen as it met endpoint.…

Novel drug therapy kills pancreatic cancer cells by reducing levels of antioxidants

July 28, 2016

Research News

Researchers demonstrate that in the specific context of pancreatic cells leading to cancer, raisin antioxidant levels should not be raised.…

To divide or not: a cellular feedback loop that enables new cells to make a fateful decision

July 21, 2016

Research News

Team explains a key mechanism to prevent aberrant cell proliferation…

Discovery of new ovarian cancer signaling hub points to target for limiting metastasis

July 10, 2016

Research News

A team of researchers at Cold Spring Harbor Laboratory discovers new insights into signaling events that underlie metastasis in ovarian cancer cells.…

Academic-industry collaboration generates elegant way of pinpointing how a new drug exerts beneficial effects

July 5, 2016

Research News

Researchers identify a new drug target in leukemia and creation of a candidate drug that hits the target.…

Basic research needs your support

June 30, 2016

Research News

CSHL partners with Research!America to find out where political candidates stand on support for basic research.…

Cancer researcher Camila dos Santos of CSHL is named a Rita Allen Foundation Scholar

June 29, 2016

Institutional News

Assistant Professor Camila dos Santos of Cold Spring Harbor Laboratory (CSHL) has been selected as one of seven 2016 Rita Allen Foundation Scholars. …

“Amazing protein diversity” is discovered in the maize plant

June 24, 2016

Research News

The genome of the corn plant “is a lot more exciting” than scientists have previously believed.…

Pew Trusts name CSHL’s Daniel Rodríguez-Leal a Latin American Fellow in Biomedical Sciences

June 9, 2016

Institutional News

Daniel Rodríguez-Leal, Ph.D., a postdoctoral investigator was selected for the Pew Latin American Fellows in the Biomedical Sciences…

Pershing Square Sohn Cancer Research Alliance awards prize to CSHL’s Christopher Vakoc

May 27, 2016

Institutional News

Associate Professor Christopher Vakoc of Cold Spring Harbor Laboratory is among seven winners of the third annual Pershing Square Sohn Prize…

ALS Ride for Life comes to Cold Spring Harbor Laboratory

May 23, 2016

Institutional News

CSHL gathered to welcome Chris Pendergast and his ALS Ride for Life team to campus on Monday, May 16.…

Discovery of new stem cell pathway indicates route to much higher yields in maize, staple crops

May 16, 2016

Research News

Researchers discover a new regulatory pathway that channels signals emanating from a plant's extremities to the stem cell niche.…

Our brain uses statistics to calculate confidence, make decisions

May 4, 2016

Research News

The brain produces feelings of confidence that inform decisions the same way statistics pulls patterns out of noisy data.…

Cold Spring Harbor Laboratory confers 90th Ph.D.

May 2, 2016

Education News

On May 1, proud friends and family mingled with distinguished scientists at the 13th commencement ceremony of the Watson School of Biological Sciences…

First structural views of the NMDA receptor in action will aid drug development

May 2, 2016

Research News

Structural biologists obtained snapshots of the activation of an important type of brain-cell receptor.…

Cold Spring Harbor Laboratory launches $75 million Center for Therapeutics Research to develop new drugs

April 22, 2016

Institutional News

CSHL announced the Center for Therapeutics Research project, applying biomedical expertise towards advancing therapeutics for genetic diseases.…

Adrian Krainer of Cold Spring Harbor Laboratory elected to American Academy of Arts and Sciences

April 20, 2016

Institutional News

Adrian Krainer was elected to the American Academy of Arts and Sciences.…

Executive in Residence to mentor scientific entrepreneurs at Cold Spring Harbor Laboratory

April 15, 2016

Institutional News

Andrew Whiteley joined the Cold Spring Harbor Laboratory Office of Technology Transfer as the first Executive in Residence.…

CSHL scientists Bo Li and Je Lee win HFSP Research Grant awards

April 12, 2016

Research News

Associate Professor Bo Li and Assistant Professor Je Lee, are among 25 teams that have won Human Frontier Science Program Research Program Grants…

U.S. Patent Office denies all 4 petitions filed by Benitec Biopharma against CSHL’s shRNA patents

April 6, 2016

Institutional News

U.S. Patent & Trademark Office has denied all 4 petitions filed by Benitec Biopharma Ltd seeking to invalidate CSHL's patents directed to shRNA.…

Neanderthals mated with modern humans much earlier than previously thought, study finds

February 12, 2016

Research News

Using several different methods of DNA analysis, an international research team has found what they consider to be strong evidence of interbreeding.…

Ancient gene network helps plants adapt to their environments

February 9, 2016

Research News

Reseachers discovered the purpose of a tool present in both mosses and flowering plants, organisms whose common ancestor dates back 450 million years.…

A consortium to map the brain is launched

February 2, 2016

Research News

The Wyss Institute for Biologically Inspired Engineering announced a cross-institutional consortium to map the brain's neural circuits.…

Christina Renna Foundation Raises $35,000 for pediatric cancer research at CSHL

January 29, 2016

Institutional News

The Christina Renna Foundation presented $35,000 to Cold Spring Harbor Laboratory (CSHL) at its 9th annual Angel's Wish Gala.…

CSHL joins nation’s cancer centers in endorsement of HPV vaccination for cancer prevention

January 27, 2016

Institutional News

Cold Spring Harbor Laboratory joined 68 other top cancer centers in issuing a statement urging increased HPV vaccination for the prevention of cancer…

The iPlant Collaborative is now called CyVerse

January 15, 2016

Institutional News

The enhanced NSF project will now provide data management and computation across scientific disciplines…

bioRxiv preprints can now be submitted directly to leading research journals

January 15, 2016

Research News

Cold Spring Harbor Laboratory announced that authors of manuscripts posted on its preprint server can now submit papers directly to leading journals.…

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