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Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments

1/12/2017

Pre-malignant aneuploid cells grew more slowly and formed smaller tumors than comparable cells with normal chromosome number, CSHL researchers found. Read the story »

Plus-sized fly: a model to understand the mechanisms underlying human obesity

1/10/2017

The fly sheds light on how the brain acts to signal “fullness” and the possibility of conferring resilience against the impact of high-fat diets Read the story »

FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL

12/24/2016

Nusinersen (Spinraza) will be used to treat young children with a severe and potentially fatal illness called spinal muscular atrophy (SMA). Read the story »

The brain atlas

12/14/2016

This episode of BasePairs looks at the problems of neuropsychiatric drug discovery, and the method by which they may soon be resolved. Read the story »

Dr. Robert Maki joins Northwell Health Cancer Institute and CSHL to direct Center for New Cancer Therapies

12/12/2016

Dr. Robert G. Maki an internationally-renowned sarcoma cancer physician and researcher, joins the leadership of the Northwell Health Cancer Institute. Read the story »

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

12/9/2016

Truncated p53 proteins, presumed unimportant, now point to new drug targets for some of "the hardest cancers" Read the story »

Gene editing yields tomatoes that flower and ripen weeks earlier

12/5/2016

Researchers use CRISPR to expand the geographical range of important food crops. Read the story »

One experiment: A drug for SMA visibly repairs defective cells

12/1/2016

Professor Adrian Krainer develops a treatment for spinal muscular atrophy, the leading genetic cause of infant death. Read the story »

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

12/1/2016

Drugs precisely targeting portions of the NMDA receptor may have applications in Alzheimer’s, depression and schizophrenia. Read the story »

When antioxidants are pro-cancer

11/15/2016

For Pancreatic Cancer Awareness Month, Base Pairs looks at the science of antioxidants and cancer. Read the story »

Focus on quiescent cells brings to light the essential role of RNA interference in transcription control

11/9/2016

RNAi and other epigenetic processes induce changes in where and when specific genes are expressed without altering their genetic code. Read the story »

Pancreas and colon tumors reprogram the liver, causing wasting and short-circuiting body’s immune response

11/8/2016

Research reveals a mechanism that causes wasting in cancer and tests a way to reverse it. Read the story »

Gene network controls how many flowers and fruits plants will produce during critical growth window

11/7/2016

Researchers use RNA sequencing to identify a network of genes that work together to determine the duration of a critical window for growth. Read the story »

Our most common infection-fighting white blood cells can be hijacked to support cancer spread

10/19/2016

Neutrophils, the most common type of white blood cell, can be taken over by cancer cells and used as an aid in metastasis. Read the story »

“Sink or swim”

10/15/2016

This episode of Base Pairs follows Professor Adrian Krainer and his experience as the first CSHL fellow. Read the story »

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Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments

Relationship between incorrect chromosome number and cancer is reassessed after surprising experiments

Plus-sized fly: a model to understand the mechanisms underlying human obesity

FDA approval of life-saving SMA drug is hailed by its researcher-inventor at CSHL

The brain atlas

Dr. Robert Maki joins Northwell Health Cancer Institute and CSHL to direct Center for New Cancer Therapies

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

Gene editing yields tomatoes that flower and ripen weeks earlier

One experiment: A drug for SMA visibly repairs defective cells

Detailed images of NMDA receptor show how zinc and a potential drug affect its function

When antioxidants are pro-cancer

Focus on quiescent cells brings to light the essential role of RNA interference in transcription control

Pancreas and colon tumors reprogram the liver, causing wasting and short-circuiting body’s immune response

Gene network controls how many flowers and fruits plants will produce during critical growth window

Our most common infection-fighting white blood cells can be hijacked to support cancer spread

“Sink or swim”

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