Never before have the pioneers of the science of retroviruses, the discoverers of human retroviruses, the developers of HIV/AIDS therapeutics, and key figures in important research findings come together to discuss the history and future of the field. Together, this interdisciplinary group will review the key scientific, epidemiological, and clinical discoveries that created this field, delve into the present science of HIV/AIDS, and discuss and debate the paths to the future control of this global pandemic, which, tragically, has persisted for more than 35 years.