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The Rich Past & Present of RNA Splicing Research at CSHL

NA splicing-or more precisely, the phenomenon that genes are interrupted-was discovered at CSHL by Rich Roberts, Tom Broker, Louise Chow, and Richard Gelinas in 1977 and was discovered independantly at MIT by former CSHL scientist Phil Sharp and his colleagues. Rich and Phil shared the Nobel Prize in 1993 for these discoveries.

In 1981, Adrian Krainer came to CSHL to pursue RNA splicing studies he had begun as a graduate student at Harvard. By then, Rich was focused on other research, but was an excellent mentor for Adrian to have around as he established his own RNA splicing research. In addition to Adrian, four other CSHL scientists-David Helfman, Nouria Hernandez, David Spector, and Rui-ming Xu-currently study or have studied particular aspects of RNA splicing.


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