Inside Jones Laboratory
Blog
Jones is CSHL’s oldest building. Since 1893, its exterior has remained virtually unchanged. Inside is a different story. Read the story »
Blog
Jones is CSHL’s oldest building. Since 1893, its exterior has remained virtually unchanged. Inside is a different story. Read the story »
Feature
That’s not the Starship Enterprise burning up in space. It’s an up-close look at precancerous pancreatic lesions and the mucus they produce. Read the story »
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CSHL played a lead role in mapping the first plant genome. Today, that breakthrough fuels a whole new understanding of life on Earth. Read the story »
News
CSHL researchers have developed a new data-driven approach that cancer centers may use to expand patient recruitment efforts. Read the story »
CSHL research has yielded insights into a number of women’s health topics, from menopause to breast cancer. Take this quiz to see how far we’ve come. Take the quiz »
News
A partnership between CSHL and the Penny’s Flight Foundation aims to find a cure for NF1, the world’s most common single-gene neurological disorder. Read the story »
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CSHL Postdoctoral Fellow Simón(e) Sun has co-authored an article titled “Rigorous Science Demands Support of Transgender Scientists.” Read the story »
What is CSHL’s John Moses doing with that glowing liquid? Watch our expert chemist get a reaction from the crowd at Industry bar in Huntington, NY. Watch the video »
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March 26: CSHL neuroscientist Arkarup Banerjee discusses “Mysteries of Language & Communication” at a special screening of sci-fi blockbuster Arrival. Read the story »
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CSHL’s Camila dos Santos and Jessica Tollkuhn offer empowering insights into breast cancer prevention, pregnancy, menopause, and hormone therapy. Read the story »
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CSHL’s Justin Kinney and Spinraza inventor Adrian Krainer tested the newly approved SMA treatment, risdiplam, and another RNA therapeutic, branaplam. Read the story »
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CSHL plant biologists have stumbled on a peculiar case involving a gene that’s key for controlling growth in tomatoes and other crops. Read the story »
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Mucus is not just snot. CSHL scientists have discovered some pancreatic cancer cells depend on it. The finding may open a new therapeutic avenue. Read the story »
This question lies at the heart of a new interdisciplinary collaboration between CSHL’s Camila dos Santos and Peter Koo. Watch the video »
News
CSHL researchers have discovered a new link between chronic stress and cancer metastasis, providing a possible path forward for new treatments. Read the story »
Blog
It’s not a sea creature. It’s in your brain. For over 20 years, this sculpture has inspired cutting-edge neuroscience research at CSHL. Read the story »
News
A tiny protein sequence with the potential to unlock new therapies against autoimmune diseases has been hiding in plain sight— until now. Read the story »
CSHL’s series of fun, interactive science talks returns to Industry bar in Huntington, NY, with a demonstration of today’s DNA sequencing technology. Watch the video »
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CSHL researchers have found that EN-1, a protein involved in neurodevelopment, can help pancreatic cancer spread throughout the body. Read the story »
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The CSHL DNA Learning Center’s LEGO DNA sequencer makes learning about the genome fun and easy for students of all ages, even kindergarteners. Read the story »
Feature
Former CSHL Fellow Carol Greider’s Nobel-winning research has led to new cancer treatments. Now, it’s helping us unravel the mysteries of aging. Read the story »
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The Christina Renna Foundation’s generous gift supports Professor Christopher Vakoc’s pioneering sarcoma research. Read the story »
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Griffin Hon, a senior at Syosset High School, studied bowel disease alongside CSHL Assistant Professor Semir Beyaz using single-cell sequencing. Read the story »
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Researchers at the CSHL Cancer Center study the links between disease and nutrition in hopes of uncovering new treatment and prevention strategies. Read the story »
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How does the brain govern communication? It’s all about timing. CSHL investigates with the help of a “musical” mouse from Costa Rica. Read the story »
Want to know the secret to a long life? So do CSHL scientists. Take this short quiz to see what they’ve found out about aging and longevity. Take the quiz »
Blog
There’s been a surge of bald eagle sightings on campus. CSHL’s Vlad Drozdoff brings us an amazing close-up look at these birds in action. Read the story »
News
CSHL's Corina Amor Vegas discovers that CAR T cells can act as a “living” drug, causing young mice to age more slowly and old mice to rejuvenate. Read the story »
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Everyone is “wired” differently. CSHL Associate Professor Jessica Tollkuhn maps the genes sex hormones use to shape developing brains. Read the story »
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One cancer gene, one cancer genome, two Cold Spring Harbor Laboratory discoveries that helped shape the face of modern cancer medicine. Read the story »
After a four-year hiatus, Cocktails & Chromosomes returned in 2023. Relive the past year’s best moments and see what’s in store for 2024. Watch the video »
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How Cold Spring Harbor Laboratory’s research on penicillin in the 1940s helped the U.S. win World War II and changed medicine forever. Read the story »
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A recent workshop at the CSHL Library & Archives shed light on the interwoven histories of the Laboratory, Long Island, NY, and the greater U.S. Read the story »
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The Cold Spring Harbor Laboratory professor and HHMI investigator steps into her new role effective January 2, 2024. Read the story »
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New Cold Spring Harbor Laboratory Director of Research Leemor Joshua-Tor shares her vision for the future of bioscience discovery. Read the story »
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Ten years ago, CSHL launched bioRxiv. Since then, the preprint server and sister site medRxiv have been key in sharing science for the good of society. Read the story »
Blog
When he’s not busy pushing the frontiers of cancer research, CSHL’s Jeremy Borniger turns his attention to the final frontier—space. Read the story »
Ever hear a mouse sing? Now you can. Listen to a pair of mice duets and see how their “songs” are helping scientists figure out how the brain works. Watch the video »
Take this short quiz to see how much you know about the science of social behavior. Take the quiz »
A decade ago, sequencing individual cells was a luxury. Today, it’s critical for biology research. Meet the scientists making it happen at CSHL. Watch the video »
The question is how! Whet your appetite for discovery with this mouthwatering talk on diet and nutrition from CSHL’s Semir Beyaz. Watch the video »
News
Carol Greider’s lab writings offer a firsthand look at her Nobel Prize-winning research—work that continues today in CSHL’s Amor Vegas lab. Read the story »
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A CSHL retreat organized by Charla Lambert offers young researchers the professional communications training missing from most science courses. Read the story »
CSHL Press leaders John Inglis and Richard Sever give us an inside look at the process and possible windows into its future. Watch the video »
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CSHL research brings scientists closer to understanding how pancreatic cancer interacts with our immune system and why immunotherapy hasn’t worked. Read the story »
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The gala honored philanthropists William Ackman & Neri Oxman and 2018 Nobel laureate Jim Allison. Read the story »
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Banbury Center think tank develops new guidelines to make short STEM training effective, inclusive, and sustainable for working professionals. Read the story »
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Fifty years ago, CSHL honored Barbara McClintock by dedicating a building in her name. Today, it is home to four innovative cancer labs. Read the story »
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CSHL’s Foundations for the Future campaign will propel the institution’s bioscience research and education programs to new heights and maximal impact. Read the story »
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Cold Spring Harbor Laboratory’s Advancement team provides an overview of the institution’s newly launched seven-acre expansion project. Read the story »
Mysterious but polite! CSHL’s Arkarup Banerjee breaks down the animals’ call-and-response routine in our latest talk at Industry in Huntington, NY. Watch the video »
News
CSHL Professor Rob Martienssen earned the award for outstanding research contributions to the field of genetics. Read the story »
For the first time, scientists at CSHL have observed gene expression as it occurs throughout an animal. See life take shape in front of your eyes. Watch the video »
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World leaders in cellular reprogramming, differentiating, repair, and regeneration gathered at Cold Spring Harbor Laboratory from October 10-14. Read the story »
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CSHL research suggests certain neurons help us tell apart different smells while others help us learn to distinguish between similar odors. Read the story »
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CSHL Professor Nicholas Tonks’ team has discovered a new way to target PTPRD, an enzyme that may help some breast cancers spread. Read the story »
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The award recognizes his breakthrough sarcoma research. This is the second year in a row that the LI Herald has honored a member of the CSHL faculty. Read the story »
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Zador and collaborators have been awarded over $2 million to fine-tune a new brain mapping technique—one that might help transform the field. Read the story »
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The SRIMS internship program equips Hofstra University medical students with the skills and tools used to conduct translational research. Read the story »
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CSHL scientists have discovered that evolution and genome editing in crops are less predictable than previously thought. Read the story »
Awareness is key to prevention and potential future treatments. Take this quiz to find out about the latest in breast cancer research at CSHL. Take the quiz »
News
Rapid evolution has streamlined bats’ immune systems. This may explain why they’re resistant to cancer and viruses like Ebola or COVID-19. Read the story »
CSHL Associate Professor Camila dos Santos unpacks the science of breast cancer prevention at Industry bar in Huntington, NY. Watch the video »
With a wide swath of the CSHL community in attendance, we got an up-close view of the action. How close? Think “camera on the ref’s head” close. Watch the video »
Teamwork, ingenuity, and perseverance triumph over sinking ships as a record 14 teams take to the waters in the eighth annual Raft Race. Watch the video »
News
New CSHL research on Rett syndrome could also have implications for autism spectrum disorders, dementia, and Alzheimer’s disease. Read the story »
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The CSHL School of Biological Sciences invites undergrads to visit campus and learn about opportunities for researchers at various career stages. Read the story »
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The husband-and-wife duo of Ukrainian pianists Anna and Dmitri Shelest will give a one-hour performance on Friday, October 6. Read the story »
Making sure chromosomes get passed down correctly is hard work. Watch, through fluorescent and cryogenic lenses, how two proteins make it happen. Watch the video »
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New National Institutes of Health initiative aims to generate an atlas of brain connections, offering new insights into neurological disorders. Read the story »
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The National Science Foundation-funded Arecibo C3 project aims to make Puerto Rico a global hub of STEM education and research. Read the story »
Pull up a stool to watch CSHL Associate Professor Ullas Pedmale speak about plants and climate change at Industry bar in Huntington, NY. Watch the video »
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The Howard Hughes Medical Institute will provide Sun, a postdoc in the Tollkuhn lab at CSHL, up to $1.5 million over a period of up to eight years. Read the story »
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The new initiative, led by CSHL Professor David Tuveson, seeks to unite the nation’s NCI-designated cancer centers to help save more patients’ lives. Read the story »
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CSHL Assistant Professor Peter Westcott may have discovered why immunotherapy often fails in certain colon cancer treatments. Read the story »
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Despite early controversy, gene-editing technology has led to major breakthroughs in biological research at CSHL and beyond. Read the story »
Fruit flies use their wings to generate “music” to attract mates. Watch the male try to woo potential partners with a little liquid courage. Watch the video »
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The American Society for Biochemistry and Molecular Biology honored CSHL President & CEO Bruce Stillman for outstanding achievement in basic research. Read the story »
Three CSHL Courses teams and a few sharks compete amid the hot August sun for glory and bragging rights. Watch the video »
News
Observing gene expression in real time, CSHL scientists identified four molecules the C. elegans worm relies on to set the tempo of its development. Read the story »
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New collaboration between CSHL’s DNA Learning Center and Oxford Nanopore Technologies puts DNA sequencing in the palms of students’ hands. Read the story »
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“Every successful medicine has its origin story,” says CSHL’s Christopher Vakoc. “And research like this is the soil from which new drugs are born.” Read the story »
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Thirty years ago, CSHL’s Rob Martienssen discovered plant gene DDM1. Now, he’s identified just how the DDM1 protein helps control inheritance. Read the story »
CSHL Assistant Professor Andrea Schorn takes us into her lab for a behind-the-scenes look at the parts of our genome that aren’t quite human. Watch the video »
Feature
Half the human genome isn’t quite human. CSHL’s Andrea Schorn gives us the inside scoop on how our DNA turned ancient viruses into essential allies. Read the story »
Since 1987, the charity swim has raised over $100 million for cancer research. Here, CSHL Assistant Professor Semir Beyaz voices his support. Watch the video »
News
One of the most famous experiments conducted at CSHL relied on the same state-of-the-art equipment found in kitchens across the U.S. in 1952—a Waring blender. Read the story »
High-tech experiments by CSHL Postdoctoral Researcher Asad Lakhani and colleagues allow us to see early 20th-century hypotheses in a whole new light. Watch the video »
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ReDACT, a new genome-editing technique invented at Cold Spring Harbor Laboratory, could bring cancer research full circle. Read the story »
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Local educators learn the ropes of genetics and bioinformatics research so they can bring it back to their students and the public. Read the story »
In the best way possible! CSHL Professor David Jackson talked about corn genetics. Plus, we gave away tickets to Tony Award-winning musical Shucked. Watch the video »
Feature
A new partnership between CSHL and one of the world’s leading biotech investors could streamline this process and help change society for the better. Read the story »
It’s not something out of science-fiction. It’s a real biomedical breakthrough. This video, with organoid expert Dr. James Wells, shows how it works. Watch the video »
News
CSHL’s 32nd Volleyball League season sees eight teams battling for the coveted Tiernan Cup and a year’s worth of bragging rights. Read the story »
An intimate discussion with the 2022 Nobel laureate courtesy of our friends at the Cold Spring Harbor Laboratory Association. Watch the video »
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Cold Spring Harbor Laboratory’s Single-Cell Analysis course teaches students the subtle art of deconstructing the human body one cell at a time. Read the story »
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CSHL and Massachusetts General Hospital researchers uncover how metastatic breast cancer slips past the immune system’s defenses in mice. Read the story »
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After nearly 40 years, CSHL remains the spot to learn the latest and hottest trends in fruit fly neuroscience. Read the story »
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Week-long program immerses girls and nonbinary students entering sixth and seventh grade in the fascinating and inspiring world of biology research. Read the story »
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The DNA Learning Center’s STARS camp offers a two-week research experience for young scientists from underrepresented communities. Read the story »
CSHL NeuroAI Scholar Kyle Daruwalla speaks to a standing-room-only crowd about AI’s energy efficiency problem. Watch the video »
News
CSHL captures never-before-seen images of the human CALHM1 channel, a mysterious cellular passageway that may be connected to Alzheimer’s disease. Read the story »
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CSHL Diversity, Equity, & Inclusion Officer Charla Lambert joins a multidisciplinary team focused on ‘redefining who a scientist could and should be.’ Read the story »
Test your knowledge of how diet and nutrition affect health and disease with this short quiz. Take the quiz »
News
The CSHL neuroscientist will receive $300,000 over three years to study singing mice. Their “songs” could help explain how the brain drives speech. Read the story »
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The initiative offers research, education, and professional development opportunities for scholars from groups that are underrepresented in science. Read the story »
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Scientists have long wondered how common steroids work and why cancer immunotherapy fails in certain patients. The answers may be one and the same. Read the story »
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The event, serving up stimulating science talks over delicious drinks, heads to Industry bar in Huntington, New York. First on tap for June 29 is AI. Read the story »
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Krainer was recognized for his pioneering research on spinal muscular atrophy and RNA therapeutics. Read the story »
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The highly prestigious award will support Zhang’s research on the role of nutrients and other environmental factors in blood cancer development. Read the story »
Take a virtual tour of CSHL’s new state-of-the-art growth chambers with plant biologist Ullas Pedmale. Watch the video »
News
CSHL researchers find that pairing keto with a prescription steroid may offer a potential treatment for pancreatic and colorectal cancer. Read the story »
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Futter is the president emerita of the American Museum of Natural History and a leading voice in education and nonprofit initiatives. Read the story »
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State-of-the-art plant growth chambers at CSHL allow scientists to mimic the effects of climate change on crops around the world. Read the story »
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Life on Earth depends on phosphorus to give DNA structure. Soon, biology’s chosen chemical could make for new cancer treatments and green materials. Read the story »
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Scientists have unknowingly encountered mysterious noise while using AI to decipher our genetic code. CSHL has found a way to cut through the fog. Read the story »
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Before it can change the world, AI must learn to walk. To help get it there, Professor Anthony Zador has proposed a new ‘embodied’ Turing test. Read the story »
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This Special Annual Report edition of CSHL’s magazine provides a look back at some of the Laboratory’s biggest stories from 2022. Read the story »
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CSHL President & CEO Bruce Stillman sees the Laboratory as a global hub for scientific expertise and a powerful launchpad for early-career scientists. Read the story »
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The conversation around autism has evolved over the past two decades. So has CSHL research. This retrospective shows how we’ve helped move the needle. Read the story »
CSHL scientists have studied the genetics of autism across hundreds of family trees. This animated video shows what they’ve found. Watch the video »
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CSHL study of more than 6,000 volunteer families overturns a long-held assumption about the genetic origins of autism spectrum disorder. Read the story »
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With access to premier technology and expertise, CSHL primes early-career scientists for breakthrough studies of autism spectrum disorder. Read the story »
Different structures and artworks around campus hint at a history of groundbreaking molecular science. Take the quiz »
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June 3: The Cinema Arts Centre in Huntington, NY presents a screening of sci-fi romance Her with a talk on AI by CSHL neuroscientist Anthony Zador. Read the story »
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Friends, family, and faculty applauded 11 Ph.D. recipients at the CSHL School of Biological Sciences’ 2023 commencement. Read the story »
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Cheadle was selected for his leadership in neuroscience research and advancing diversity, equity, and inclusion in science. Read the story »
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The School of Biological Sciences awarded 11 Ph.D. degrees this year. Here, the graduates reflect on their time and experiences at CSHL. Read the story »
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The CSHL School of Biological Sciences awarded honorary degrees to author Stephen S. Hall and educator Nouria Hernandez. Read the story »
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This basic rule of thumb is helping CSHL’s quantitative biologists train AI to get a better read of the human genome. Read the story »
In this video, CSHL Assistant Professor Semir Beyaz shows how what you eat continues to influence your health long after you’ve digested it. Watch the video »
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CSHL researchers have found that high levels of a protein called SRSF1 can cause pancreatitis and jumpstart tumor development. Read the story »
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The award will support Tollkuhn’s research on the role of sex hormones in brain development, behavior, and diseases like Alzheimer’s and Parkinson’s. Read the story »
April is National Autism Awareness Month. Test your knowledge of autism spectrum disorders with this short quiz. Take the quiz »
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CSHL hosts the first-ever Science Forward symposium, a two-day event for early-career researchers from historically marginalized groups. Read the story »
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He helped pioneer the field. It changed medicine. Now, he joins a group of renowned scientists and physicians aiming to take it to the next level. Read the story »
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CSHL Professor Adrian Krainer, the man behind the “miracle drug” known as Spinraza®, has found a way to fight a deadly pediatric brain cancer in mice. Read the story »
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The same genes can cause different subtypes of tumors. Now, CSHL can recreate them in the lab. The approach could lead to new cancer treatments. Read the story »
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CSHL neuroscientists discover that certain neurons in the brain’s central amygdala are key to helping us learn about threats and rewards. Read the story »
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CSHL researchers have created a powerful new molecule that combats antibiotic-resistant superbugs. Read the story »
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A new algorithm created by CSHL researchers can help predict the health effects of millions of genetic variants found within a single person’s genome. Read the story »
Watch as the famed Italian actress chats with neuroscientist Helen Hou about Charles Darwin, women in STEM, stage fright, and much more. Watch the video »
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This Malaysian jungle plant produces a chemical with remarkable anticancer properties. Now, CSHL scientists can synthesize that chemical in the lab. Read the story »
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This spring, CSHL will introduce an app-connected, wheelchair-accessible trolley bus at its campus in Cold Spring Harbor, New York. Read the story »
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Explore the history of CSHL’s Meetings & Courses programs, along with their legacy of pioneering research and science education, from 1890 to today. Read the story »
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Perennials may hold the key to sustainable farming. CSHL scientists are decoding the genes that let these plants withstand the test of time. Read the story »
Step inside the lab of CSHL Associate Professor Jeremy C. Borniger, where he and his team are rewiring the nervous system to combat cancer cells. Watch the video »
Feature
Imagine an electronic device that can eliminate tumors. In our exclusive interview, Jeremy Borniger offers an inside look at this exciting new field. Read the story »
This weekend, the worlds of art and science are one at CSHL as Rossellini presents her new play, Darwin’s Smile. Get your sneak peek here. Watch the video »
Take this 8-bit trip along the brain’s olfactory circuits to see what happens up there when you smell something. Watch the video »
News
A shape-shifter with a protruding arm and an appetite for unwanted RNA! CSHL biochemists identify the hidden talents of a mysterious molecule. Read the story »
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Elementary, middle, and high school students on break can get real-life lab experience through a new series of science workshops at the DNALC. Read the story »
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The Cold Spring Harbor Laboratory School of Biological Sciences is now accredited by the New England Commission of Higher Education. Read the story »
The relationship between a mother and child is special. This video shows how moms’ brains are wired to reward motherly care. Watch the video »
Think you’re plugged into the latest artificial intelligence advancements? Test your tech knowledge with this quiz on AI and computational biology. Take the quiz »
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The generous gift supports CSHL’s Sarcoma Research Project and Professor Christopher Vakoc’s ongoing rhabdomyosarcoma research. Read the story »
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CSHL Partners for the Future student Sean Krivitsky is a semifinalist in one the nation's most prestigious high school science competitions. Read the story »
Test your knowledge of evolution with this quiz, inspired by the March 2023 performances of Isabella Rossellini’s play, Darwin’s Smile, at CSHL. Take the quiz »
Take an up-close look at what CSHL Professor Zachary Lippman describes as “one of the coolest evolutionary novelties to emerge in plants.” Watch the video »
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CSHL scientists have discovered that shutting down the ETV6 protein in Ewing sarcoma cells can dramatically slow their growth. Read the story »
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The DNALC Saturday DNA! sessions offer fun, interactive science workshops for students curious about genetics and how it affects everyday life. Read the story »
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Deerfield commits up to $130 million over 10 years to support drug development efforts. Read the story »
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Moms know best, but how do they learn it? A new study offers insights into the mental reward system that nurtures maternal instinct. Read the story »
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The money will help the Laboratory purchase new supercomputers and artificial intelligence equipment used in cancer research. Read the story »
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