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Description
The Microarray
Shared Resource provides Cancer Center members with access to
state-of-the-art microarray platform technologies such as expression
arrays, and several other molecular techniques that have become
available over the last several years. Libraries for gene targeting
experiments in mice or functional inactivation by RNAi are stored
and distributed by this Shared Resource. All services are LIMS
supported for sample tracking and quality assurance. |
Services
Microarray chips: |
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The
facility prints microarrays for expression analysis using the
Compugen Human 19K, and Mouse 22K oligonucleotide libraries. |
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The Microarray
Shared Resource provides access to Affymetrix Genechips,
and is now a member of the Affymetrix Core Lab Program. |
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Custom
microarraying is also available for any user-provided samples
including, Oligonucleotides, PCR Products, Living Arrays, Proteins
and Antibodies. |
| Array
services: |
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Complete
labeling and hybridization services are available with RNA
samples submitted by users. |
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Training
is offered for all steps of the microarray experimental process
for users interested in carrying out their own experiments. |
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Users can
attend the Hotelling Service, a comprehensive workshop service
from experimental design through to data management and publishing. |
| Array
Bioinformatics: |
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Data
analysis and gene annotation services, training and assistance
are provided for both Affymetrix and printed array platforms. |
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Data
warehousing, and some data analysis, are available through
a secure web based server, using the BioArray Software Environment
(BASE) Relational Database. |
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Training and support are also available for GCOS, MAS 5.0,
Spotfire, S-plus, Bio-conductor and associated R Based Tools. |
| Maintenance
and distribution of libraries: |
Libraries
for gene targeting experiments in mice or functional inactivation
by RNAi are stored and distributed internally by this Shared
Resource. |
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Mouse
Gene Targeting Library |
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RNAi library |
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