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Bioinformatics

The Laboratory's bioinformatics program-the use of computers to analyze, store, and distribute scientific data, a kind of scientific information technology-has continued to evolve. Bioinformatics scientist Michael Zhang has been at CSHL since 1991 and studies DNA sequence pattern recognition. Recently, he was joined by three new computational biologists: Andy Neuwald, Andy Reiner, and Lincoln Stein. Andy Neuwald brings expertise in understanding the relationship between protein sequence and structure. Andy Reiner studies mechanisms for data storage and management, and Lincoln Stein is an expert in genome research and sequencing. In addition to their own research, all are providing valuable contributions to Dick McCombie's DNA sequencing efforts. Tom Marr, a member of the Laboratory's bioinformatics team since 1989, spent 1997 in transition between the Laboratory and Genomica Corporation in Boulder, Colorado. Tom is still involved in research projects here at Cold Spring Harbor, but he is now president and C.E.O. of Genomica.

The goal of the Laboratory's bioinformatics program is to develop and use computerized methods to study biology. As genomic research advances, so too does the need for efficient analysis, reliable storage, and accessibility of data. Genome scientists make up one of the most open group of research scientists today, posting programs and results on searchable Internet sites as soon as they are assembled. The bioinformatics group at the Laboratory will continue to work on original research and development projects and to collaborate with other Cold Spring Harbor scientists on a wide range of projects.


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