Ph.D., University of Missouri, Columbia, 2008
|Unlike animals, plants neither have specific organs that see or hear various stimuli, yet, plants are sensitive to their surrounding environment and modify their development according to various external signals. My lab studies how the environment of a plant modulates its growth and development. Understanding environmental control of growth will have far-reaching implications for agriculture, energy production, and many other human activities.|
Plants and animals interact with their environment. Since plants are incapable to move around, they are sensitive to their surrounding environment and modify their development according to external signals. Plants face variability in growth conditions – temperature, light quality and quantity, herbivores, pathogens, water availability etc. Yet, plants respond to these biotic and abiotic factors and survive substantial fluctuations in its environment. Plants also must balance the range of potential threats and benefits confronting it and should make appropriate decisions on resource allocation. Such adaptability is essential for the sessile nature of the plants. The mechanisms that underlie this adaptability likely involve complex signaling to generate the appropriate response. In some adaptive responses, for example, when the plants have to cope with climate change and increased competition for light, there is a decrease in productivity (yield, biomass) as the plant relocates resources to better adapt.
The Pedmale Lab’s research goals seek to determine the mechanisms behind how a plant perceives and successfully adapts to its environment. We also aim to understand how a plant must integrate intrinsic and extrinsic cues and ‘decide’ how best to respond to environmental cues. Understanding how plants deal with, and respond to a multitude of environmental signals could help to develop crops that cope with unfavorable growth conditions without significant changes in yield.
Pedmale, U. V. and Huang, S. S. and Zander, M. and Cole, B. J. and Hetzel, J. and Ljung, K. and Reis, P. A. and Sridevi, P. and Nito, K. and Nery, J. R. and Ecker, J. R. and Chory, J. (2016) Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light. Cell 164(1-2) pp. 233-45.
Kaiserli, E. and Paldi, K. and O'Donnell, L. and Batalov, O. and Pedmale, U. V. and Nusinow, D. A. and Kay, S. A. and Chory, J. (2015) Integration of Light and Photoperiodic Signaling in Transcriptional Nuclear Foci. Dev Cell 35(3) pp. 311-21.
Li, L. and Ljung, K. and Breton, G. and Schmitz, R. J. and Pruneda-Paz, J. and Cowing-Zitron, C. and Cole, B. J. and Ivans, L. J. and Pedmale, U. V. and Jung, H. S. and Ecker, J. R. and Kay, S. A. and Chory, J. (2012) Linking photoreceptor excitation to changes in plant architecture. Genes Dev 26(8) pp. 785-90.
Roberts, D. and Pedmale, U. V. and Morrow, J. and Sachdev, S. and Lechner, E. and Tang, X. and Zheng, N. and Hannink, M. and Genschik, P. and Liscum, E. (2011) Modulation of phototropic responsiveness in Arabidopsis through ubiquitination of phototropin 1 by the CUL3-Ring E3 ubiquitin ligase CRL3(NPH3). Plant Cell 23(10) pp. 3627-40.
Pedmale, U. V. and Celaya, R. B. and Liscum, E. (2010) Phototropism: mechanism and outcomes. Arabidopsis Book 8pp. e0125.Additional materials of the author at
CSHL Institutional Repository