Cold Spring Harbor, NY --
Cold Spring Harbor Laboratory (CSHL) has announced a research collaboration with Pfizer Inc. to develop a next-generation human short hairpin RNA (shRNA) library which could be used to silence gene expression via the process of RNA interference (RNAi) and identify new therapeutic targets in cancer.
“CSHL is pleased to partner with Pfizer to create a shRNA technology platform that could speed the validation of drug targets and open doors to new therapeutic options in a range of cancers,” said CSHL President Bruce Stillman, Ph.D. The CSHL-Pfizer agreement will bring the Laboratory’s academic researchers together with Pfizer’s scientists in both the technology development and training environments.
“Pfizer is pleased to be involved in this partnership, which will marry cutting-edge shRNA technologies with our efforts in cancer genetics and complex tumor models toward the singular goal of identifying and validating novel targets for cancer therapeutics,” said Bob Abraham, Pfizer’s Oncology Chief Scientific Officer
CSHL is the birthplace of the first-generation shRNA library developed by HHMI Investigator and CSHL Professor Greg Hannon. Dr. Hannon has pioneered the use of RNAi techniques to study mammalian genes, including development of comprehensive collections of synthetic shRNAs that can be used to specifically silence the expression of most human, mouse, and rat genes. These materials are available to the academic community. About Cold Spring Harbor Laboratory
Founded in 1890, Cold Spring Harbor Laboratory (CSHL) has shaped contemporary biomedical research and education with programs in cancer, neuroscience, plant biology and quantitative biology. CSHL is ranked number one in the world by Thomson Reuters for impact of its research in molecular biology and genetics. The Laboratory has been home to eight Nobel Prize winners. Today, CSHL's multidisciplinary scientific community is more than 360 scientists strong and its Meetings & Courses program hosts more than 12,500 scientists from around the world each year to its Long Island campus and its China center. Tens of thousands more benefit from the research, reviews, and ideas published in journals and books distributed internationally by CSHL Press. The Laboratory's education arm also includes a graduate school and programs for undergraduates as well as middle and high school students and teachers. CSHL is a private, not-for-profit institution on the north shore of Long Island. For more information, visit www.cshl.edu