CSHL Professor Thomas Gingeras is a member of an international consortium that has spent 4 years annotatiing the genomes of two model organisms, C. elegans, a roundowrm, and Drosophila melanogaster, the common fruit fly. The project, called modENCODE, for Model organism Encyclopedia of DNA Elements, seeks to compile comprehensive data sets across a developmental time course and in multiple cell lines, in each of the model organisms. In a paper published Dec. 23rd in Science, Gingeras and colleagues report on "Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE." With the work that stands behind this paper, the annotated portion of the Drosophila genome has now tripled, revealing a functional regulatory network in stunning detail. Thomas Gingeras describes the work in this podcast, recorded Dec. 23, 2010 with Peter Tarr, a science writer at CSHL.
Read about Thomas Gingeras' genome studies in the Harbor Transcript:
The gene redefined